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Alessandro Cembran

20022020
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  • 2 Similar Profiles
Photoisomerization Chemical Compounds
Chromophores Chemical Compounds
Rhodopsin Chemical Compounds
Excited states Chemical Compounds
Cyclic AMP-Dependent Protein Kinases Medicine & Life Sciences
Molecular Dynamics Simulation Medicine & Life Sciences
Proteins Chemical Compounds
Potential energy surfaces Chemical Compounds

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Projects 2016 2020

Uncovering the intrinsic factors mediating prion protein toxicity in Drosophila

Fernandez-Funez, P. & Cembran, A.

Winston & Maxine Wallin Neuro Disc Fund

1/1/20 → 12/31/20

Project: Research project

Intrinsic Factor
Drosophila
Prion Proteins

Entropic Springs in Tandem Repeat Proteins

Hinderliter, A. & Cembran, A.

National Science Foundation

8/1/16 → 7/31/20

Project: Research project

tandem repeat sequences
proteins

Research Output 2002 2018

Dynamics of Dystrophin's Actin-Binding Domain

Fealey, M. E., Horn, B., Coffman, C., Miller, R., Lin, A. Y., Thompson, A. R., Schramel, J., Groth, E., Hinderliter, A., Cembran, A. & Thomas, D. D., Aug 7 2018, In : Biophysical journal. 115, 3, p. 445-454 10 p.

Research output: Contribution to journal › Article

Open Access
Dystrophin
Actins
Utrophin
Electrons
Molecular Dynamics Simulation
8 Citations (Scopus)

Tuning Sulfur Oxidation States on Thioether-Bridged Peptide Macrocycles for Modulation of Protein Interactions

Perell, G. T., Staebell, R. L., Hairani, M., Cembran, A. & Pomerantz, W. C. K., Sep 19 2017, In : ChemBioChem. 18, 18, p. 1836-1844 9 p.

Research output: Contribution to journal › Article

Sulfides
Sulfur
Myeloid-Lymphoid Leukemia Protein
Tuning
Modulation
27 Citations (Scopus)

Oxidation increases the strength of the methionine-aromatic interaction

Lewis, A. K., Dunleavy, K. M., Senkow, T. L., Her, C., Horn, B. T., Jersett, M. A., Mahling, R., McCarthy, M. R., Perell, G. T., Valley, C. C., Karim, C. B., Gao, J., Pomerantz, W. C. K., Thomas, D. D., Cembran, A., Hinderliter, A. & Sachs, J. N., Oct 1 2016, In : Nature Chemical Biology. 12, 10, p. 860-866 7 p.

Research output: Contribution to journal › Article

Methionine
Proteins
Databases
Lymphotoxin-alpha
Protein Folding
29 Citations (Scopus)

Dysfunctional conformational dynamics of protein kinase a induced by a lethal mutant of phospholamban hinder phosphorylation

Kim, J., Masterson, L. R., Cembran, A., Verardi, R., Shi, L., Gao, J., Taylor, S. S. & Veglia, G., Mar 24 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 12, p. 3716-3721 6 p.

Research output: Contribution to journal › Article

Protein Kinases
Phosphotransferases
Cyclic AMP-Dependent Protein Kinases
Phosphorylation
Myocardial Contraction
8 Citations (Scopus)

Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution

Desai, B. J., Goto, Y., Cembran, A., Fedorov, A. A., Almo, S. C., Gao, J., Suga, H. & Gerlt, J. A., Oct 21 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 42, p. 15066-15071 6 p.

Research output: Contribution to journal › Article

Carboxy-Lyases
Amides
Hydrogen
Esters
Amber