1995 …2021

Research output per year

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Research Output

Action potential duration restitution portraits of mammalian ventricular myocytes: Role of calcium current

Tolkacheva, E. G., Anumonwo, J. M. B. & Jalife, J., Oct 2006, In : Biophysical journal. 91, 7, p. 2735-2745 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Acute cardiovascular and hemodynamic effects of vagus nerve stimulation in conscious hypertensive rats

Annoni, E. M. & Tolkacheva, E. G., Oct 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., p. 3685-3688 4 p. 8513025. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Analysis of the Fenton-Karma model through an approximation by a one-dimensional map

Tolkacheva, E. G., Schaeffer, D. G., Gauthier, D. J. & Mitchell, C. C., Dec 2002, In : Chaos. 12, 4, p. 1034-1042 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

An ionically based mapping model with memory for cardiac restitution

Schaeffer, D. G., Cain, J. W., Gauthier, D. J., Kalb, S. S., Oliver, R. A., Tolkacheva, E. G., Ying, W. & Krassowska, W., Feb 1 2007, In : Bulletin of mathematical biology. 69, 2, p. 459-482 24 p.

Research output: Contribution to journalArticle

21 Scopus citations

A reduced order model for spatiotemporal dynamics and control of cardiac alternans

Zhao, X. & Tolkacheva, E. G., Jan 1 2018, Advances in Control Design Methods; Advances in Nonlinear Control; Advances in Robotics; Assistive and Rehabilitation Robotics; Automotive Dynamics and Emerging Powertrain Technologies; Automotive Systems; Bio Engineering Applications; Bio-Mechatronics and Physical Human Robot Interaction; Biomedical and Neural Systems; Biomedical and Neural Systems Modeling, Diagnostics, and Healthcare. American Society of Mechanical Engineers (ASME), (ASME 2018 Dynamic Systems and Control Conference, DSCC 2018; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia

Cerrone, M., Noujaim, S. F., Tolkacheva, E. G., Talkachou, A., O'Connell, R., Berenfeld, O., Anumonwo, J., Pandit, S. V., Vikstrom, K., Napolitano, C., Priori, S. G. & Jalife, J., Nov 1 2007, In : Circulation research. 101, 10, p. 1039-1048 10 p.

Research output: Contribution to journalArticle

197 Scopus citations

Atrial GIRK channels mediate the effects of vagus nerve stimulation on heart rate dynamics and arrhythmogenesis

Lee, S. W., Anderson, A., Guzman, P. A., Nakano, A., Tolkacheva, E. G. & Wickman, K., Jul 19 2018, In : Frontiers in Physiology. 9, JUL, 943.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Characterizing Spatial Dynamics of Bifurcation to Alternans in Isolated Whole Rabbit Hearts Based on Alternate Pacing

Kulkarni, K., Visweswaran, R., Zhao, X. & Tolkacheva, E. G., Jan 1 2015, In : BioMed Research International. 2015, 170768.

Research output: Contribution to journalArticle

5 Scopus citations

Chronic cyclic vagus nerve stimulation has beneficial electrophysiological effects on healthy hearts in the absence of autonomic imbalance

Lee, S. W., Li, Q., Libbus, I., Xie, X., Kenknight, B. H., Garry, M. G. & Talkachova, A., May 1 2016, In : Physiological Reports. 4, 9, p. 1-8 8 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Chronic low-level vagus nerve stimulation improves long-term survival in salt-sensitive hypertensive rats

Annoni, E. M., Van Helden, D., Guo, Y., Levac, B., Libbus, I., KenKnight, B. H., Osborn, J. W. & Tolkacheva, E. G., Jan 1 2019, In : Frontiers in Physiology. 10, JAN, 25.

Research output: Contribution to journalArticle

Open Access

Computational and Mathematical Methods in Cardiovascular Diseases

Tolkacheva, E. G., Zhao, X., Zlochiver, S. & Mori, Y., Jan 1 2017, In : Computational and mathematical methods in medicine. 2017, 4205735.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Condition for alternans and its control in a two-dimensional mapping model of paced cardiac dynamics

Tolkacheva, E. G., Romeo, M. M., Guerraty, M. & Gauthier, D. J., Mar 2004, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 69, 3, p. 31904 1 p., 031904.

Research output: Contribution to journalArticle

47 Scopus citations

Condition for alternans and stability of the 1: 1 response pattern in a "memory" model of paced cardiac dynamics

Tolkacheva, E. G., Schaeffer, D. G., Gauthier, D. J. & Krassowska, W., Mar 1 2003, In : Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 67, 3, p. 31904 1 p.

Research output: Contribution to journalArticle

86 Scopus citations

Constant DI pacing suppresses cardiac alternans formation in numerical cable models

Zlochiver, S., Johnson, C. & Tolkacheva, E. G., Sep 1 2017, In : Chaos. 27, 9, 093903.

Research output: Contribution to journalArticle

6 Scopus citations

Control of cardiac alternans in a mapping model with memory

Tolkacheva, E. G., Romeo, M. M. & Gauthier, D. J., Jul 15 2004, In : Physica D: Nonlinear Phenomena. 194, 3-4, p. 385-391 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
Open Access

Effect of chirped laser pulse narrowing by reflection from a nonlinear DFB structure

Afanas'ev, A. A., Samson, B. A. & Tolkacheva, E. G., Jan 1998, In : Journal of Modern Optics. 45, 1, p. 91-101 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of space modulation of laser beams in a nonlinear DFB-structure

Afanas'ev, A. A., Dritz, V. V., Samson, B. A. & Tolkacheva, E. G., Jan 1 1996, Technical Digest - European Quantum Electronics Conference. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Expression and relevance of the G protein-gated K+ channel in the mouse ventricle

Anderson, A., Kulkarni, K., Marron Fernandez De Velasco, E., Carlblom, N., Xia, Z., Nakano, A., Martemyanov, K. A., Tolkacheva, E. G. & Wickman, K., Dec 1 2018, In : Scientific reports. 8, 1, 1192.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Feasibility of visualizing higher regions of Shannon entropy in atrial fibrillation patients

Arunachalam, S. P., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Nov 4 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., p. 4499-4502 4 p. 7319394. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Scopus citations

Free fatty acid effects on the atrial myocardium: Membrane ionic currents are remodeled by the disruption of T-tubular architecture

O'Connell, R. P., Musa, H., Gomez, M. S. M., Avula, U. M., Herron, T. J., Kalifa, J., Anumonwo, J. M. B. & Talkachova, A., Aug 14 2015, In : PloS one. 10, 8, e0133052.

Research output: Contribution to journalArticle

15 Scopus citations

Heart rate variability and alternans formation in the heart: The role of feedback in cardiac dynamics

McIntyre, S. D., Kakade, V., Mori, Y. & Tolkacheva, E. G., Jun 7 2014, In : Journal of Theoretical Biology. 350, p. 90-97 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Improved multiscale entropy technique with nearest-neighbor moving-average kernel for nonlinear and nonstationary short-time biomedical signal analysis

Arunachalam, S. P., Kapa, S., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Jan 1 2018, In : Journal of healthcare engineering. 2018, 8632436.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Intelligent fractional-order PID (FOPID) heart rate controller for cardiac pacemaker

Arunachalam, S. P., Kapa, S., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Dec 27 2016, 2016 IEEE Healthcare Innovation Point-of-Care Technologies Conference, HI-POCT 2016. Institute of Electrical and Electronics Engineers Inc., p. 105-108 4 p. 7797708. (2016 IEEE Healthcare Innovation Point-of-Care Technologies Conference, HI-POCT 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations
18 Scopus citations

Intermittent vagal nerve stimulation alters the electrophysiological properties of atrium in the myocardial infarction rat model

Xie, X., Lee, S. W., Johnson, C., Ippolito, J., Kenknight, B. H. & Tolkacheva, E. G., Nov 2 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., Vol. 2014. p. 1575-1578 4 p. 6943904. (2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations
1 Scopus citations
15 Scopus citations

Kir2.3 isoform confers pH sensitivity to heteromeric Kir2.1/Kir2.3 channels in HEK293 cells

Muñoz, V., Vaidyanathan, R., Tolkacheva, E. G., Dhamoon, A. S., Taffet, S. M. & Anumonwo, J. M. B., Apr 1 2007, In : Heart Rhythm. 4, 4, p. 487-496 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Kurtosis as a statistical approach to identify the pivot point of the rotor

Arunachalam, S. P., Annoni, E. M., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., p. 497-500 4 p. 7590748. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2016-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Local onset of voltage and calcium alternans in the heart

McIntyre, S. D., Mori, Y. & Tolkacheva, E. G., Dec 1 2011, ASME 2011 Dynamic Systems and Control Conference and Bath/ASME Symposium on Fluid Power and Motion Control, DSCC 2011. p. 607-610 4 p. (ASME 2011 Dynamic Systems and Control Conference and Bath/ASME Symposium on Fluid Power and Motion Control, DSCC 2011; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mechanisms underlying the antifibrillatory action of hyperkalemia in guinea pig hearts

Pandit, S. V., Warren, M., Mironov, S., Tolkacheva, E. G., Kalifa, J., Berenfeld, O. & Jalife, J., May 19 2010, In : Biophysical journal. 98, 10, p. 2091-2101 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Miniaturized radio frequency telemetric pacemaker with anti-arrhythmic pacing protocol

Kulkarni, K., Tan, S. Y. & Tolkacheva, E. G., Jan 1 2014, In : Journal of Medical Devices, Transactions of the ASME. 8, 2, 020909.

Research output: Contribution to journalArticle

Modified Sequence Method to Assess Baroreflex Sensitivity in Rats

Schultz, J., Annoni, E. M. & Tolkacheva, E. G., Oct 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., p. 2764-2767 4 p. 8512734. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2018-July).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Multiscale frequency technique robustly discriminates normal sinus rhythm and atrial fibrillation on a single lead electrocardiogram

Arunachalam, S. P., Annoni, E. M., Kapa, S., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Jan 1 2017, 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017. International Society of Automation (ISA), (54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017; vol. 2017-March).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Nonlinear dynamics of periodically paced cardiac tissue

Tolkacheva, E. G. & Zhao, X., May 1 2012, In : Nonlinear Dynamics. 68, 3, p. 347-363 17 p.

Research output: Contribution to journalReview article

10 Scopus citations

Novel multiscale frequency approach to identify the pivot point of the rotor

Arunachalam, S. P., Annoni, E. M., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Jun 1 2016, In : Journal of Medical Devices, Transactions of the ASME. 10, 2, 020948.

Research output: Contribution to journalArticle

7 Scopus citations

Novel quantitative analytical approaches for rotor identification and associated implications for mapping

Annoni, E. M., Arunachalam, S. P., Kapa, S., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Feb 2018, In : IEEE Transactions on Biomedical Engineering. 65, 2, p. 273-281 9 p., 8068247.

Research output: Contribution to journalArticle

10 Scopus citations

Optical mapping of electrical heterogeneities in the heart during global ischemia

Matiukas, A., Pertsov, A. M., Kothari, P., Cram, A. & Tolkacheva, E. G., 2009, Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009: Engineering the Future of Biomedicine, EMBC 2009. IEEE Computer Society, p. 6321-6324 4 p. 5333176. (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Scopus citations

Pro-arrhythmic effect of heart rate variability during periodic pacing

Kulkarni, K., Lee, S. W. & Tolkacheva, E. G., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., p. 149-152 4 p. 7590662. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2016-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Rate-dependent propagation of cardiac action potentials in a one-dimensional fiber

Cain, J. W., Tolkacheva, E. G., Schaeffer, D. G. & Gauthier, D. J., Jan 1 2004, In : Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics. 70, 6, 1 p.

Research output: Contribution to journalArticle

16 Scopus citations

Real-Time Closed Loop Diastolic Interval Control Prevents Cardiac Alternans in Isolated Whole Rabbit Hearts

Kulkarni, K., Lee, S. W., Kluck, R. & Tolkacheva, E. G., Apr 1 2018, In : Annals of Biomedical Engineering. 46, 4, p. 555-566 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Real-time feedback based control of cardiac restitution using optical mapping

Kulkarni, K. & Tolkacheva, E. G., Nov 4 2015, 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., p. 5920-5923 4 p. 7319739. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Restitution in mapping models with an arbitrary amount of memory

Kalb, S. S., Tolkacheva, E. G., Schaeffer, D. G., Gauthier, D. J. & Krassowska, W., Jun 2005, In : Chaos. 15, 2, 023701.

Research output: Contribution to journalArticle

23 Scopus citations

Robust discrimination of normal sinus rhythm and atrial fibrillation on ECG using a multiscale frequency technique

Arunachalam, S. P., Annoni, E. M., Kapa, S., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Jan 1 2017, Frontiers in Biomedical Devices, BIOMED - 2017 Design of Medical Devices Conference, DMD 2017. American Society of Mechanical Engineers, (Frontiers in Biomedical Devices, BIOMED - 2017 Design of Medical Devices Conference, DMD 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
3 Scopus citations

Role of conduction velocity restitution and short-term memory in the development of action potential duration alternans in isolated rabbit hearts

Mironov, S., Jalife, J. & Tolkacheva, E. G., Jul 1 2008, In : Circulation. 118, 1, p. 17-25 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Rotor pivot point identification using recurrence period density entropy

Arunachalam, S. P., Kapa, S., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Jan 1 2017, 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017. International Society of Automation (ISA), (54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017; vol. 2017-March).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Rotor pivot point identification with intrinsic mode function complexity index using empirical mode decomposition

Arunachalam, S. P., Mulpuru, S. K., Friedman, P. A. & Tolkacheva, E. G., Jul 8 2016, 2016 IEEE EMBS International Student Conference: Expanding the Boundaries of Biomedical Engineering and Healthcare, ISC 2016 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 7508597. (2016 IEEE EMBS International Student Conference: Expanding the Boundaries of Biomedical Engineering and Healthcare, ISC 2016 - Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Spatial instability of counterpropagating waves in nonlinear distributed feedback structures

Afanas’ev, A. A., Tolkacheva, E. G., Tredicce, J. & Volkov, V. M., Jan 1 1999, In : Physical Review A - Atomic, Molecular, and Optical Physics. 60, 3, p. 2375-2379 5 p.

Research output: Contribution to journalArticle

1 Scopus citations