Keyphrases
Pulmonary Artery Smooth muscle Cells (PASMCs)
85%
Pulmonary Arterial Hypertension
83%
Pulmonary Hypertension
71%
Ca2+
28%
Idiopathic Pulmonary Arterial Hypertension
27%
Pulmonary Vascular
22%
Pulmonary Artery Smooth muscle Cell Proliferation
22%
Smooth muscle Cells
22%
Therapeutic Target
21%
Experimental Pulmonary Hypertension
20%
Pulmonary Microvascular Endothelial Cells (PMVECs)
20%
Pulmonary Vascular Disease
19%
Vascular Remodeling
19%
Mechanosensitive Channel
18%
Piezo1
18%
Pulmonary Vascular Remodeling
18%
Stromal Interaction Molecule 1 (STIM1)
16%
Alveolar Hypoxia
15%
Pulmonary Artery Pressure
15%
Pathogenic Role
14%
Endothelial-to-mesenchymal Transition (EndMT)
13%
Hypoxia
13%
Mouse Lung
13%
Ca2+ Signaling
13%
Mouse Model
12%
Right Ventricle
12%
Pulmonary Vasoconstriction
11%
Lung
11%
Functional Role
10%
Severe Pulmonary Hypertension
10%
Calcium-sensing Receptor (CaSR)
10%
Pulmonary Vascular Resistance
10%
Platelet-derived Growth factor-BB (PDGF-BB)
10%
Voltage-gated K+ Channels
10%
TRPC6
10%
Vasoconstriction
10%
Jagged1
9%
Hypoxia-inducible factor-1α (HIF-1α)
9%
Pathogenic Mechanism
9%
Hypoxia Response
9%
Idiopathic PAH
9%
Acute Hypoxia
9%
Hematocrit
9%
Hypoxia-inducible Factor 2
9%
CALHM1
9%
Transient Receptor Potential Vanilloid 1 Channel
9%
Calcium Homeostasis
9%
Inter-individual Variation
9%
Comorbidity
9%
Vascular Reactivity
9%
Medicine and Dentistry
Pulmonary Hypertension
66%
Calcium Ion
34%
Pulmonary Artery Smooth Muscle Cell
32%
Cell Proliferation
26%
Vascular Remodeling
22%
Upregulation
22%
Smooth Muscle Cell
18%
Arterial Smooth Muscle Cell
18%
Endothelial Cell
16%
Pulmonary Artery
16%
Experimental Pulmonary Hypertension
14%
Calcium Signaling
10%
Vanilloid Receptor 1
10%
Platelet Derived Growth Factor
9%
Pulmonary Vascular Disease
9%
Endothelial Dysfunction
9%
Cardiac Catheterization
9%
Platelet Derived Growth Factor Receptor
9%
Smooth Muscle
9%
Hypoxic Pulmonary Vasoconstriction
9%
Stromal Interaction Molecule 2
9%
Calcium Homeostasis
9%
Polycyclic Aromatic Hydrocarbon
9%
Capsaicin
9%
Mechanistic Target of Rapamycin
6%
Vascular Disease
6%
Disease
6%
Lung Vascular Resistance
6%
down Regulation
5%
Ex Vivo
5%
Small Interfering RNA
5%
Lung Vasoconstriction
5%
Vasoconstriction
5%
Pharmacology, Toxicology and Pharmaceutical Science
Pulmonary Hypertension
100%
Calcium Ion
53%
Vascular Remodeling
27%
Mouse
24%
Pulmonary Vascular Disease
19%
Potassium Channel
18%
Hypoxia
16%
Experimental Pulmonary Hypertension
16%
Stromal Interaction Molecule 2
13%
Mouse Model
11%
Calcium Sensing Receptor
10%
Vanilloid Receptor 1
10%
Protein P53
9%
Hypoxic Lung Vasoconstriction
9%
Endothelial Dysfunction
9%
Capsaicin
9%
Polycyclic Aromatic Hydrocarbon
9%
Halofuginone
9%
microRNA
9%
microRNA 29b
8%
Disease
8%
Potassium Ion
7%
Hypoxia-Induced Pulmonary Hypertension
7%
Mammalian Target of Rapamycin
6%
Vascular Disease
6%
Calcium Channel
5%
Heart Right Ventricle Failure
5%
