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Research interests
Miller Lab Consortium. To date, our team has treated more than 400 patients with natural killer cell infusions and over a hundred patients with therapies that activate their own natural killer cells. We've retrospectively analyzed more than 5000 patients and enrolled more than 500 patients in prospective trials.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Phase 1/2 Study of IDP-023 as a Single Agent and in Combination with Antibody Therapies inPatients with Advanced Hematologic Cancers
Merino, A. M. (PI)
7/25/23 → 7/31/33
Project: Research project
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FT576-101: A Phase I Study of FT576 as Monotherapy and in Combination with Daratumumab in Subjects with Relapsed/Refractory Multiple Myeloma 576
Merino, A. M. (PI)
11/15/22 → 11/15/27
Project: Research project
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Understanding and improving responses to adaptive NK cell therapy for leukemia and multiple myeloma
Merino, A. M. (PI)
NIH NATIONAL CANCER INSTITUTE (NCI)
3/5/21 → 2/28/26
Project: Research project
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Enhancing the ability of natural killer cells to kill renal cell carcinoma
Merino, A. M. (PI)
AMERICAN SOCIETY OF CLINICAL ONCOLOGY
7/1/19 → 12/31/20
Project: Research project
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Impact of melphalan day -1 vs day -2 on outcomes after autologous stem cell transplant for multiple myeloma
Merino, A., Shanley, R., Rashid, F., Langer, J., Dolan, M., Tu, S., Jurdi, N. E., Rogosheske, J., Hanna, K., DeFor, T., Janakiram, M. & Weisdorf, D., 2024, In: Frontiers in immunology. 15, 1310752.Research output: Contribution to journal › Article › peer-review
Open Access -
Advances in NK cell therapy for hematologic malignancies: NK source, persistence and tumor targeting.
Merino, A., Maakaron, J. & Bachanova, V., Jul 2023, In: Blood Reviews. 60, 101073.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Cichocki, F., Bjordahl, R., Goodridge, J. P., Mahmood, S., Gaidarova, S., Abujarour, R., Davis, Z. B., Merino, A., Tuininga, K., Wang, H., Kumar, A., Groff, B., Witty, A., Bonello, G., Huffman, J., Dailey, T., Lee, T. T., Malmberg, K. J., Walcheck, B. & Höpken, U. & 3 others, , Dec 2022, In: Nature communications. 13, 1, 7341.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Early Adaptive Natural Killer Cell Expansion Is Associated with Decreased Relapse After Autologous Transplantation for Multiple Myeloma
Merino, A. M., Mehta, R. S., Luo, X., Kim, H., De For, T., Janakiram, M., Cooley, S. A., Wangen, R., Cichocki, F., Weisdorf, D. J., Miller, J. S. & Bachanova, V., Apr 1 2021, In: Transplantation and Cellular Therapy. 27, 4, p. 310.e1-310.e6Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Unraveling exhaustion in adaptive and conventional NK cells
Merino, A. M., Kim, H., Miller, J. S. & Cichocki, F., Oct 1 2020, In: Journal of Leukocyte Biology. 108, 4, p. 1361-1368 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access36 Scopus citations