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Aaron L Sarver

20012024
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Beauty Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Osteosarcoma Medicine & Life Sciences
Insertional Mutagenesis Medicine & Life Sciences
Genes Medicine & Life Sciences
Canidae Medicine & Life Sciences
Genome Medicine & Life Sciences

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Projects 2009 2024

Cancer Center Support Grant

Yee, D., AbuSalah, A. M., Basu, S., Beckman, K. B., Bielinsky, A. K., Cooley, S. A., De For, T. E., Falconer, S. N., Felices, M., Griffin, T. J., Hallstrom, T. C., Hatsukami, D. K., Hendrickson, E. A., Hirsch, B. A., Joseph, A. M., Kirstein, M. N., Konety, B. R., Koopmeiners, J., Kuntz, K. M., Lange, C. A., Largaespada, D. A., Le, C. T., LeBeau, A., Lindgren, B. R., Luo, X., Mc Carthy, J. B., McKenna, D. H., Miller, J. S., Moriarity, B. S., Nelson, H. H., O'Sullivan, G., Ondrey, F. G., Pennell, C. A., Petersen, A. J., Peterson, B. A., Peterson, L. A., Sarver, A. L., Shimizu, Y., Siegfried, J. M., Temiz, N. A., Turesky, R., Vogel, R., Wagner, J. E., Wang, J., Weigel, B. J., Weisdorf, D. J., Woo, J. & Yamamoto, M.

NIH NATIONAL CANCER INSTITUTE (NCI)

2/1/19 → 1/31/24

Project: Research project

Neoplasms

Novel Immunotherapy for Sarcomas using Combination Oncolytic VSV and IL-18 Superkine

Modiano, J., Henson, M. S., Koopmeiners, J., O'Sullivan, G. & Sarver, A. L.

V FOUNDATION FOR CANCER RESEARCH

2/1/19 → 2/1/22

Project: Research project

Interleukin-18
Sarcoma
Immunotherapy

Bioinformatics approaches to solve the "Missing Driver

Sarver, A. L.

NIH NATIONAL CANCER INSTITUTE (NCI)

9/15/16 → 8/31/21

Project: Research project

Bioinformatics
Tumors

Discovery and Pathogenetic Significance of Chromosome Tr

Modiano, J., Kim, J. H. & Sarver, A. L.

NIH NATIONAL CANCER INSTITUTE (NCI)

12/1/15 → 11/30/18

Project: Research project

Chromosome
Translocation

Discovery and pathogenic significance of chromosome tran

Kim, J. H. & Sarver, A. L.

NATL CANINE CANCER FDN

4/15/15 → 10/14/17

Project: Research project

Hemangiosarcoma
Canidae
Chromosomes

Research Output 2001 2019

Identification of Cancer Genes Based on De Novo Transposon Insertion Site Analysis Using RNA and DNA Sequencing

Sarver, A. L., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 73-79 7 p. (Methods in Molecular Biology; vol. 1907).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

RNA Sequence Analysis
Neoplasm Genes
DNA Sequence Analysis
Genome
Beauty

Insertional mutagenesis using the Sleeping Beauty transposon system identifies drivers of erythroleukemia in mice

Loeb, K. R., Hughes, B. T., Fissel, B. M., Osteen, N. J., Knoblaugh, S. E., Grim, J. E., Drury, L. J., Sarver, A. L., Dupuy, A. J. & Clurman, B. E., Dec 1 2019, In : Scientific reports. 9, 1, 5488.

Research output: Contribution to journal › Article

Open Access
Beauty
Cyclin E
Leukemia, Erythroblastic, Acute
Insertional Mutagenesis
Oncogenes
1 Citation (Scopus)

Risk factors for development of Canine and Human Osteosarcoma: A comparative review

Makielski, K. M., Mills, L. J., Sarver, A. L., Henson, M. S., Spector, L. G., Naik, S. & Modiano, J. F., Jun 1 2019, In : Veterinary Sciences. 6, 2, 48.

Research output: Contribution to journal › Review article

Open Access
osteosarcoma
Human Development
Osteosarcoma
Canidae
risk factors

Sleeping beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors

Beckmann, P. J., Larson, J. D., Larsson, A. T., Ostergaard, J. P., Wagner, S., Rahrmann, E. P., Shamsan, G. A., Otto, G. M., Williams, R. L., Wang, J., Lee, C., Tschida, B. R., Das, P., Dubuc, A. M., Moriarity, B. S., Picard, D., Wu, X., Rodriguez, F. J., Rosemarie, Q., Krebs, R. D. & 13 others, Molan, A. M., Demer, A. M., Frees, M. M., Rizzardi, A. E., Schmechel, S. C., Eberhart, C. G., Jenkins, R. B., Wechsler-Reya, R. J., Odde, D. J., Huang, A., Taylor, M. D., Sarver, A. L. & Largaespada, D. A., Mar 1 2019, In : Cancer Research. 79, 5, p. 905-917 13 p.

Research output: Contribution to journal › Article

Beauty
Central Nervous System Neoplasms
Medulloblastoma
Insertional Mutagenesis
Primitive Neuroectodermal Tumors
1 Citation (Scopus)

Treatment combining CD200 immune checkpoint inhibitor and tumor-lysate vaccination after surgery for pet dogs with high-grade glioma

Olin, M. R., Ampudia-Mesias, E., Pennell, C. A., Sarver, A., Chen, C. C., Moertel, C. L., Hunt, M. A. & Pluhar, G. E., Jan 1 2019, In : Cancers. 11, 2, 137.

Research output: Contribution to journal › Article

Open Access
Pets
Glioma
Vaccination
Dogs
Antigen-Presenting Cells