20082019

Research output per year

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Research Output

2019

Methods for thermal denaturation studies of nucleic acids in complex with fluorogenic dyes

Aufdembrink, L. M., Hoog, T. G., Pawlak, M. R., Bachan, B. F., Heili, J. M. & Engelhart, A. E., 2019, Methods in Enzymology. Hargrove, A. E. (ed.). Academic Press Inc., p. 23-43 21 p. (Methods in Enzymology; vol. 623).

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Catalysis of Template-Directed Nonenzymatic RNA Copying by Iron(II)

Jin, L., Engelhart, A. E., Zhang, W., Adamala, K. & Szostak, J. W., Nov 7 2018, In : Journal of the American Chemical Society. 140, 44, p. 15016-15021 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Real-Time Visualization of in Vitro Transcription of a Fluorescent RNA Aptamer: An Experiment for the Upper-Division Undergraduate or First-Year Graduate Laboratory

Heili, J. M., Gomez-Garcia, J., Gaut, N. J., Cash, B. W., Aufdembrink, L. M., Heffron, B. A., Shirley, J. D., Carlson, E. E., Adamala, K. P. & Engelhart, A. E., Oct 9 2018, In : Journal of Chemical Education. 95, 10, p. 1867-1871 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2017
3 Scopus citations
2016

Collaboration between primitive cell membranes and soluble catalysts

Adamala, K. P., Engelhart, A. E. & Szostak, J. W., Mar 21 2016, In : Nature communications. 7, 11041.

Research output: Contribution to journalArticle

24 Scopus citations
2015

Construction of a liposome dialyzer for the preparation of high-value, small-volume liposome formulations

Adamala, K., Engelhart, A. E., Kamat, N. P., Jin, L. & Szostak, J. W., Jun 30 2015, In : Nature Protocols. 10, 6, p. 927-938 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Generation of functional RNAs from inactive oligonucleotide complexes by non-enzymatic primer extension

Adamala, K., Engelhart, A. E. & Szostak, J. W., Jan 14 2015, In : Journal of the American Chemical Society. 137, 1, p. 483-489 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Ester formation and hydrolysis during wet-dry cycles: Generation of far-from-equilibrium polymers in a model prebiotic reaction

Mamajanov, I., Macdonald, P. J., Ying, J., Duncanson, D. M., Dowdy, G. R., Walker, C. A., Engelhart, A. E., Fernández, F. M., Grover, M. A., Hud, N. V. & Schork, F. J., Feb 25 2014, In : Macromolecules. 47, 4, p. 1334-1343 10 p.

Research output: Contribution to journalArticle

40 Scopus citations

Structural insights into the effects of 2′-5′ linkages on the RNA duplex

Sheng, J., Li, L., Engelhart, A. E., Gan, J., Wang, J. & Szostak, J. W., Feb 25 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 8, p. 3050-3055 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
2013

Functional RNAs exhibit tolerance for non-heritable 2′-5′ versus 3′-5′ backbone heterogeneity

Engelhart, A. E., Powner, M. W. & Szostak, J. W., Mar 24 2013, In : Nature Chemistry. 5, 5, p. 390-394 5 p.

Research output: Contribution to journalArticle

61 Scopus citations
2012

Nonenzymatic Ligation of DNA with a Reversible Step and a Final Linkage that Can Be Used in PCR

Engelhart, A. E., Cafferty, B. J., Okafor, C. D., Chen, M. C., Williams, L. D., Lynn, D. G. & Hud, N. V., May 1 2012, In : ChemBioChem. 13, 8, p. 1121-1124 4 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

DNA and RNA in anhydrous media: Duplex, triplex, and G-quadruplex secondary structures in a deep eutectic solvent

Mamajanov, I., Engelhart, A. E., Bean, H. D. & Hud, N. V., Aug 23 2010, In : Angewandte Chemie - International Edition. 49, 36, p. 6310-6314 5 p.

Research output: Contribution to journalArticle

116 Scopus citations

Intercalation as a means to suppress cyclization and promote polymerization of base-pairing oligonucleotides in a prebiotic world

Horowitz, E. D., Engelhart, A. E., Chen, M. C., Quarles, K. A., Smith, M. W., Lynn, D. G. & Hud, N. V., Mar 23 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 12, p. 5288-5293 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
2009

Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites

Tsai, A. G., Engelhart, A. E., Hatmal, M. M., Houston, S. I., Hud, N. V., Haworth, I. S. & Lieber, M. R., Mar 13 2009, In : Journal of Biological Chemistry. 284, 11, p. 7157-7164 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
16 Scopus citations
2008

Submicromolar, selective G-quadruplex ligands from one pot: Thermodynamic and structural studies of human telomeric DNA binding by azacyanines

Çetinkol, Ö. P., Engelhart, A. E., Nanjunda, R. K., Wilson, W. D. & Hud, N. V., Aug 12 2008, In : ChemBioChem. 9, 12, p. 1889-1892 4 p.

Research output: Contribution to journalArticle

18 Scopus citations