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2020

CD200 checkpoint reversal: A novel approach to immunotherapy a C

Xiong, Z., Mesias, E. A., Elizabeth Pluhar, G., Rathe, S. K., Largaespada, D. A., Sham, Y. Y., Moertel, C. L. & Olin, M. R., Jan 1 2020, In : Clinical Cancer Research. 26, 1, p. 232-241 10 p.

Research output: Contribution to journalArticle

Open Access

Developmental pathogenicity of 4-repeat human tau is lost with the P301L mutation in genetically matched tau-transgenic mice

Gamache, J. E., Kemper, L., Steuer, E., Leinonen-Wright, K., Choquette, J. M., Hlynialuk, C., Benzow, K., Vossel, K. A., Xia, W., Koob, M. D. & Ashe, K. H., Jan 2 2020, In : Journal of Neuroscience. 40, 1, p. 220-236 17 p.

Research output: Contribution to journalArticle

Dopamine-Evoked Synaptic Regulation in the Nucleus Accumbens Requires Astrocyte Activity

Corkrum, M., Covelo, A., Lines, J., Bellocchio, L., Pisansky, M., Loke, K., Quintana, R., Rothwell, P. E., Lujan, R., Marsicano, G., Martin, E. D., Thomas, M. J., Kofuji, P. & Araque, A., Mar 18 2020, In : Neuron. 105, 6, p. 1036-1047.e5

Research output: Contribution to journalArticle

Evidence for rapid phenotypic and behavioural shifts in a recently established cavefish population

McGaugh, S. E., Weaver, S., Gilbertson, E. N., Garrett, B., Rudeen, M. L., Grieb, S., Roberts, J., Donny, A., Marchetto, P. & Gluesenkamp, A. G., Jan 1 2020, In : Biological Journal of the Linnean Society. 129, 1, p. 143-161 19 p.

Research output: Contribution to journalArticle

1 Scopus citations

Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer

Glumac, P. M., Gallant, J. P., Shapovalova, M., Li, Y., Murugan, P., Gupta, S., Coleman, I. M., Nelson, P. S., Dehm, S. M. & Lebeau, A. M., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1054-1064

Research output: Contribution to journalArticle

Generation of human endothelium in pig embryos deficient in ETV2

Das, S., Koyano-Nakagawa, N., Gafni, O., Maeng, G., Singh, B. N., Rasmussen, T., Pan, X., Choi, K-D., Mickelson, D., Gong, W., Pota, P., Weaver, C. V., Kren, S., Hanna, J. H., Yannopoulos, D., Garry, M. G. & Garry, D. J., Feb 24 2020, In : Nature biotechnology.

Research output: Contribution to journalArticle

Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1

Najt, C. P., Khan, S. A., Heden, T. D., Witthuhn, B. A., Perez, M., Heier, J. L., Mead, L. E., Franklin, M. P., Karanja, K. K., Graham, M. J., Mashek, M. T., Bernlohr, D. A., Parker, L., Chow, L. S. & Mashek, D. G., Feb 20 2020, In : Molecular Cell. 77, 4, p. 810-824.e8

Research output: Contribution to journalArticle

Open Access

Microalgal swimming signatures and neutral lipids production across growth phases

You, J., Mallery, K., Mashek, D. G., Sanders, M., Hong, J. & Hondzo, M., Apr 1 2020, In : Biotechnology and bioengineering. 117, 4, p. 970-980 11 p.

Research output: Contribution to journalArticle

Photodynamic Therapy for the Treatment of Glioblastoma

Cramer, S. W. & Chen, C. C., Jan 21 2020, In : Frontiers in Surgery. 6

Research output: Contribution to journalArticle

Physical-chemical interactions between dental materials surface, salivary pellicle and Streptococcus gordonii

Sang, T., Ye, Z., Fischer, N. G., Skoe, E. P., Echeverría, C., Wu, J. & Aparicio, C., Jun 2020, In : Colloids and Surfaces B: Biointerfaces. 190, 110938.

Research output: Contribution to journalArticle

Polyplexes Are Endocytosed by and Trafficked within Filopodia

Ingle, N. P., Hexum, J. K. & Reineke, T. M., Jan 1 2020, (Accepted/In press) In : Biomacromolecules.

Research output: Contribution to journalArticle

Topoisomerase II SUMOylation activates a metaphase checkpoint via Haspin and Aurora B kinases

Pandey, N., Keifenheim, D., Yoshida, M. M., Hassebroek, V. A., Soroka, C., Azuma, Y. & Clarke, D. J., Jan 6 2020, In : The Journal of cell biology. 219, 1

Research output: Contribution to journalArticle

Open Access
2019

A conserved mechanism of APOBEC3 relocalization by herpesviral ribonucleotide reductase large subunits

Cheng, A. Z., Moraes, S. N., Attarian, C., Yockteng-Melgar, J., Jarvis, M. C., Biolatti, M., Galitska, G., Dell'Oste, V., Frappier, L., Bierle, C. J., Rice, S. A. & Harris, R. S., Dec 1 2019, In : Journal of virology. 9, 23, e01539-19.

Research output: Contribution to journalArticle

1 Scopus citations

An integrated platform for mucin-type O-glycosylation network generation and visualization

Le, T., O’Brien, C., Gupta, U., Sousa, G., Daoutidis, P. & Hu, W-S., Jun 2019, In : Biotechnology and bioengineering. 116, 6, p. 1341-1354 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
1 Scopus citations

Cortex-wide neural interfacing via transparent polymer skulls

Ghanbari, L., Carter, R. E., Rynes, M. L., Dominguez, J., Chen, G., Naik, A., Hu, J., Sagar, M. A. K., Haltom, L., Mossazghi, N., Gray, M. M., West, S. L., Eliceiri, K. W., Ebner, T. J. & Bangalore Kodandaramaiah, S., Dec 1 2019, In : Nature communications. 10, 1, 1500.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Craniobot: A computer numerical controlled robot for cranial microsurgeries

Ghanbari, L., Rynes, M. L., Hu, J., Schulman, D. S., Johnson, G. W., Laroque, M., Shull, G. M. & Bangalore Kodandaramaiah, S., Dec 1 2019, In : Scientific reports. 9, 1, 1023.

Research output: Contribution to journalArticle

3 Scopus citations

CtIP is essential for telomere replication

Stroik, S., Kurtz, K. & Hendrickson, E. A., Sep 26 2019, In : Nucleic acids research. 47, 17, p. 8927-8940 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Dentin Priming with Amphipathic Antimicrobial Peptides

Moussa, D. G., Kirihara, J. A., Ye, Z., Fischer, N. G., Khot, J., Witthuhn, B. A. & Aparicio, C., Sep 1 2019, In : Journal of dental research. 98, 10, p. 1112-1121 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Developing a Protein Scaffolding System for Rapid Enzyme Immobilization and Optimization of Enzyme Functions for Biocatalysis

Zhang, G., Johnston, T., Quin, M. B. & Schmidt-Dannert, C., Aug 16 2019, In : ACS Synthetic Biology. 8, 8, p. 1867-1876 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Development of a Biolabeling System Using Ferromagnetic Nanowires

Zhou, W., Um, J., Zhang, Y., Nelson, A. P., Nemati, Z., Modiano, J., Stadler, B. J. & Franklin, R. R., Jun 2019, In : IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology. 3, 2, p. 134-142 9 p., 8585028.

Research output: Contribution to journalArticle

2 Scopus citations

Development of a cross-reactive monoclonal antibody for detecting the tumor stroma

Hintz, H. M., Cowan, A. E., Shapovalova, M. & LeBeau, A., May 15 2019, In : Bioconjugate Chemistry. 30, 5, p. 1466-1476 11 p.

Research output: Contribution to journalArticle

Discovery of HSPG2 (Perlecan) as a Therapeutic Target in Triple Negative Breast Cancer

Kalscheuer, S., Khanna, V., Kim, H., Li, S., Sachdev, D., DeCarlo, A., Yang, D. & Panyam, J., Dec 1 2019, In : Scientific reports. 9, 1, 12492.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

Saha, A., Taylor, P. A., Lees, C. J., Panoskaltsis-Mortari, A., Osborn, M. J., Feser, C. J., Thangavelu, G., Melchinger, W., Refaeli, Y., Hill, G. R., Munn, D. H., Murphy, W. J., Serody, J. S., Maillard, I., Kreymborg, K., van den Brink, M., Dong, C., Huang, S., Zang, X., Allison, J. P. & 2 others, Zeiser, R. & Blazar, B. R., Jan 1 2019, In : JCI Insight. 4, 19, e127716.

Research output: Contribution to journalArticle

Open Access

Functional analysis and development of a CRISPR/Cas9 allelic series for a CPR5 ortholog necessary for proper growth of soybean trichomes

Campbell, B. W., Hoyle, J. W., Bucciarelli, B., Stec, A. O., Samac, D. A., Parrott, W. A. & Stupar, R. M., Dec 1 2019, In : Scientific reports. 9, 1, 14757.

Research output: Contribution to journalArticle

Open Access

G i/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission

Durkee, C. A., Covelo, A., Lines, J., Kofuji, P., Aguilar, J. & Araque, A., Jun 2019, In : Glia. 67, 6, p. 1076-1093 18 p.

Research output: Contribution to journalArticle

7 Scopus citations

Glycopolycation-DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution

Phillips, H. R., Tolstyka, Z. P., Hall, B. C., Hexum, J. K., Hackett, P. B. & Reineke, T. M., Apr 8 2019, In : Biomacromolecules. 20, 4, p. 1530-1544 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Imaging the distribution of iron oxide nanoparticles in hypothermic perfused tissues

Ring, H. L., Gao, Z., Sharma, A., Han, Z., Lee, C., Brockbank, K. G. M., Greene, E. D., Helke, K. L., Chen, Z., Campbell, L. H., Weegman, B., Davis, M., Taylor, M., Giwa, S., Fahy, G. M., Wowk, B., Pagotan, R., Bischof, J. C. & Garwood, M., Jan 1 2019, (Accepted/In press) In : Magnetic resonance in medicine. 83, 5, p. 1750-1759 10 p.

Research output: Contribution to journalArticle

Improving payload capacity and anti-tumor efficacy of mesenchymal stem cells using tat peptide functionalized polymeric nanoparticles

Moku, G., Layek, B., Trautman, L., Putnam, S., Panyam, J. & Prabha, S., Apr 2019, In : Cancers. 11, 4, 491.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Intercellular transfer of oncogenic KRAS via tunneling nanotubes introduces intracellular mutational heterogeneity in colon cancer cells

Desir, S., Wong, P., Turbyville, T., Chen, D., Shetty, M., Clark, C., Zhai, E., Romin, Y., Manova-Todorova, K., Starr, T., Nissley, D. V., Steer, C. J., Subramanian, S. & Lou, E., Jul 2019, In : Cancers. 11, 7, 892.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Mast cells induce blood brain barrier damage in SCD by causing endoplasmic reticulum stress in the endothelium

Tran, H., Mittal, A., Sagi, V., Luk, K., Nguyen, A., Gupta, M., Nguyen, J., Lamarre, Y., Lei, J., Guedes, A. & Gupta, K., Jan 29 2019, In : Frontiers in Cellular Neuroscience. 13, p. 1-12 12 p., 56.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

MCPH1 is essential for cellular adaptation to the G2-phase decatenation checkpoint

Arroyo, M., Kuriyama, R., Guerrero, I., Keifenheim, D., Cañuelo, A., Calahorra, J., Sánchez, A., Clarke, D. J. & Marchal, J. A., Jul 1 2019, In : FASEB Journal. 33, 7, p. 8363-8374 12 p.

Research output: Contribution to journalArticle

Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density

Csizmar, C. M., Petersburg, J. R., Perry, T. J., Rozumalski, L., Hackel, B. J. & Wagner, C. R., Jan 9 2019, In : Journal of the American Chemical Society. 141, 1, p. 251-261 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Mutation of a Conserved Motif of PP2C.D Phosphatases Confers SAUR Immunity and Constitutive Activity

Wong, J. H., Spartz, A. K., Park, M., Du, M. & Gray, W. M., Sep 1 2019, In : Plant physiology. 181, 1, p. 353-366 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

NanoSIMS imaging reveals metabolic stratification within current-producing biofilms

Chadwick, G. L., Otero, F. J., Gralnick, J. A., Bond, D. R. & Orphan, V. J., Oct 8 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 41, p. 20716-20724 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Novel long-range inhibitory nNOS-expressing hippocampal cells

Wick, Z. C., Tetzlaff, M. R. & Krook-Magnuson, E., Oct 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access

Optimized filopodia formation requires myosin tail domain cooperation

Arthur, A. L., Songster, L. D., Sirkia, H., Bhattacharya, A., Kikuti, C., Borrega, F. P., Houdusse, A. & Titus, M. A., Oct 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22196-22204 9 p.

Research output: Contribution to journalArticle

PEG10 promoter-driven expression of reporter genes enables molecular imaging of lethal prostate cancer

Shapovalova, M., Lee, J. K., Li, Y., Griend, D. J. V., Coleman, I. M., Nelson, P. S., Dehm, S. M. & LeBeau, A. M., Nov 1 2019, In : Cancer Research. 79, 21, p. 5668-5680 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Sleeping beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors

Beckmann, P. J., Larson, J. D., Larsson, A. T., Ostergaard, J. P., Wagner, S., Rahrmann, E. P., Shamsan, G. A., Otto, G. M., Williams, R. L., Wang, J., Lee, C., Tschida, B. R., Das, P., Dubuc, A. M., Moriarity, B. S., Picard, D., Wu, X., Rodriguez, F. J., Rosemarie, Q., Krebs, R. D. & 13 others, Molan, A. M., Demer, A. M., Frees, M. M., Rizzardi, A. E., Schmechel, S. C., Eberhart, C. G., Jenkins, R. B., Wechsler-Reya, R. J., Odde, D. J., Huang, A., Taylor, M. D., Sarver, A. L. & Largaespada, D. A., Mar 1 2019, In : Cancer Research. 79, 5, p. 905-917 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy

Singh, B., Covelo, A., Martell-Martínez, H., Nanclares, C., Sherman, M. A., Okematti, E., Meints, J., Teravskis, P. J., Gallardo, C., Savonenko, A. V., Benneyworth, M. A., Lesne, S. E., Liao, D., Araque, A. & Lee, M. K., Oct 1 2019, In : Acta Neuropathologica. 138, 4, p. 551-574 24 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

The DNA deaminase APOBEC3B interacts with the cell-cycle protein CDK4 and disrupts CDK4-mediated nuclear import of cyclin D1

McCann, J. L., Klein, M. M., Leland, E. M., Law, E. K., Brown, W. L., Salamango, D. J. & Harris, R., Jan 1 2019, In : Journal of Biological Chemistry. 294, 32, p. 12099-12111 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The impact of TCR signal strength on resident memory T cell formation during influenza virus infection

Fiege, J. K., Stone, I. A., Fay, E. J., Markman, M. W., Wijeyesinghe, S., Macchietto, M., Shen, S., Masopust, D. & Langlois, R. A., Aug 15 2019, In : Journal of Immunology. 203, 4, p. 936-945 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

The Role of RNA in HIV-1 Vif-Mediated Degradation of APOBEC3H

Wang, J., Becker, J. T., Shi, K., Lauer, K. V., Salamango, D. J., Aihara, H., Shaban, N. M. & Harris, R. S., Dec 6 2019, In : Journal of Molecular Biology. 431, 24, p. 5019-5031 13 p.

Research output: Contribution to journalArticle