Research Output 1992 2019

2018

Increasing Cas9-mediated homology-directed repair efficiency through covalent tethering of DNA repair template

Aird, E. J., Lovendahl, K. N., St Martin, A., Harris, R. & Gordon, W. R., 2018, In : Communications Biology- Nature. 1, 54.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
Ribonucleoproteins
DNA Repair
Genome

Involvement of the VGF-derived peptide TLQP-62 in nerve injury-induced hypersensitivity and spinal neuroplasticity

Skorput, A. G. J., Zhang, X., Waataja, J. J., Peterson, C. D., Riedl, M. S., Kitto, K. F., Truong, H., Huffman, C., Salton, S. R., Fairbanks, C. A., Honda, C. N. & Vulchanova, L., Sep 1 2018, In : Pain. 159, 9, p. 1802-1813 12 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Hypersensitivity
Neuralgia
Peptides
Spinal Cord
2 Citations (Scopus)

Microtubule-Actomyosin Mechanical Cooperation during Contact Guidance Sensing

Tabdanov, E. D., Puram, V., Zhovmer, A. & Provenzano, P., Oct 9 2018, In : Cell reports. 25, 2, p. 328-338.e6

Research output: Contribution to journalArticle

Actomyosin
Microtubules
Tumors
Cells
Stiffness
21 Citations (Scopus)

Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling

Verma, M., Asakura, Y., Murakonda, B. S. R., Pengo, T., Latroche, C., Chazaud, B., McLoon, L. K. & Asakura, A., Oct 4 2018, In : Cell Stem Cell. 23, 4, p. 530-543.e9

Research output: Contribution to journalArticle

Muscle Cells
Vascular Endothelial Growth Factor A
Blood Vessels
Endothelial Cells
Muscles
10 Citations (Scopus)

Nano-engineered mesenchymal stem cells increase therapeutic efficacy of anticancer drug through true active tumor targeting

Layek, B., Sadhukha, T., Panyam, J. & Prabha, S., Jun 1 2018, In : Molecular Cancer Therapeutics. 17, 6, p. 1196-1206 11 p.

Research output: Contribution to journalArticle

Open Access
Mesenchymal Stromal Cells
Paclitaxel
Pharmaceutical Preparations
Neoplasms
Nanoparticles
27 Citations (Scopus)

Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy

Kim, H., Niu, L., Larson, P., Kucaba, T. A., Murphy, K. A., James, B. R., Ferguson, D. M., Griffith, T. S. & Panyam, J., May 1 2018, In : Biomaterials. 164, p. 38-53 16 p.

Research output: Contribution to journalArticle

T-cells
Immunotherapy
Nanoparticles
Vaccines
Tumors

Principles of computer numerical control applied to small research animal surgical procedures

Rynes, M., Ghanbari, L., Hu, J. J., Schulman, D. S., Johnson, G., Laroque, M. & Bangalore Kodandaramaiah, S., Jan 1 2018.

Research output: Contribution to conferencePaper

Animals
Tissue
Milling machines
Drilling
Machining

Robotic platform for the delivery of gene products into single cells in organotypic slices of the developing mouse brain

Shull, G., Haffner, C., Huttner, W., Taverna, E. & Bangalore Kodandaramaiah, S., Jan 1 2018.

Research output: Contribution to conferencePaper

Brain
Robotics
Genes
Dyes
Computer vision
1 Citation (Scopus)

Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury

Patil, N., Truong, V., Holmberg, M. H., Lavoie, N. S., McCoy, M. R., Dutton, J. R., Holmberg, E. G. & Parr, A. M., Aug 1 2018, In : Journal of neurotrauma. 35, 15, p. 1745-1754 10 p.

Research output: Contribution to journalArticle

Open Access
Rose Bengal
Spinal Cord Injuries
Neuroglia
Cicatrix
Safety
21 Citations (Scopus)

Self-Assembling Protein Scaffold System for Easy in Vitro Coimmobilization of Biocatalytic Cascade Enzymes

Zhang, G., Quin, M. B. & Schmidt-Dannert, C., Jun 1 2018, In : ACS Catalysis. 8, 6, p. 5611-5620 10 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Scaffolds
Enzymes
Proteins
Enzyme immobilization
Open Access
rho-Associated Kinases
Albuminuria
Morphogenesis
Allografts
Fibrosis
1 Citation (Scopus)

Transcriptomal signatures of vaccine adjuvants and accessory immunostimulation of sentinel cells by toll-like receptor 2/6 agonists

Salyer, A. C. D. & David, S. A., Jul 3 2018, In : Human Vaccines and Immunotherapeutics. 14, 7, p. 1686-1696 11 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 6
Toll-Like Receptor 2
Immunization
Vaccines
Fibroblasts
2017
4 Citations (Scopus)

Adsorption and Biodegradation of Aromatic Chemicals by Bacteria Encapsulated in a Hydrophobic Silica Gel

Sakkos, J. K., Mutlu, B. R., Wackett, L. P. & Aksan, A., Aug 16 2017, In : ACS Applied Materials and Interfaces. 9, 32, p. 26848-26858 11 p.

Research output: Contribution to journalArticle

Silica Gel
Silica gel
Biodegradation
Silicon Dioxide
Bacteria
19 Citations (Scopus)

An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition

Forcade, E., Paz, K., Flynn, R., Griesenauer, B., Amet, T., Li, W., Liu, L., Bakoyannis, G., Jiang, D., Chu, H. W., Lobera, M., Yang, J., Wilkes, D. S., Du, J., Gartlan, K., Hill, G. R., MacDonald, K. P., Espada, E. L., Blanco, P., Serody, J. S. & 7 others, Koreth, J., Cutler, C. S., Antin, J. H., Soiffer, R. J., Ritz, J., Paczesny, S. & Blazar, B. R., Jun 15 2017, In : JCI Insight. 2, 12

Research output: Contribution to journalArticle

Open Access
T-Lymphocyte Subsets
Graft vs Host Disease
Pharmacology
T-Lymphocytes
Interleukin-17
7 Citations (Scopus)

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors

Lo, C. H., Vunnam, N., Lewis, A. K., Chiu, T. L., Brummel, B. E., Schaaf, T. M., Grant, B. D., Bawaskar, P., Thomas, D. D. & Sachs, J. N., Sep 1 2017, In : SLAS Discovery. 22, 8, p. 950-961 12 p.

Research output: Contribution to journalArticle

Open Access
Tumor Necrosis Factor Receptors
Screening
triclabendazole
Throughput
Ligands
16 Citations (Scopus)
Open Access
Axonal Transport
Secretory Vesicles
Phosphoric Monoester Hydrolases
Phosphotransferases
Transcription Factor AP-1
50 Citations (Scopus)

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism

Sathyanarayan, A., Mashek, M. T. & Mashek, D., Apr 4 2017, In : Cell reports. 19, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Sirtuin 1
Autophagy
Lipase
Lipids
Liver
26 Citations (Scopus)

Gold Nanorod Induced Warming of Embryos from the Cryogenic State Enhances Viability

Khosla, K., Wang, Y., Hagedorn, M., Qin, Z. & Bischof, J. C., Aug 22 2017, In : ACS Nano. 11, 8, p. 7869-7878 10 p.

Research output: Contribution to journalArticle

embryos
Nanorods
viability
Gold
Cryogenics
15 Citations (Scopus)

High-Throughput spectral and lifetime-based FRET screening in living cells to identify small-molecule effectors of SERCA

Schaaf, T. M., Peterson, K. C., Grant, B. D., Bawaskar, P., Yuen, S., Li, J., Muretta, J. M., Gillispie, G. D. & Thomas, D. D., Jan 1 2017, In : SLAS Discovery. 22, 3, p. 262-273 12 p.

Research output: Contribution to journalArticle

Fluorescence Resonance Energy Transfer
Calcium-Transporting ATPases
Endoplasmic Reticulum
Screening
Cells
10 Citations (Scopus)

Imaging Tunneling Membrane Tubes Elucidates Cell Communication in Tumors

Thayanithy, V., Desir, S., Gholami, S., Romin, Y., Fujisawa, S., Manova-Todorova, K., Steer, C. J., Subramanian, S., Fong, Y. & Moore, M. A. S., Oct 1 2017, In : Trends in Cancer. 3, 10, p. 678-685 8 p.

Research output: Contribution to journalReview article

Nanotubes
Cell Communication
Membranes
Neoplasms
Microscopy
6 Citations (Scopus)
Open Access
Metabotropic Glutamate Receptors
Opioid Receptors
Estrogen Receptors
Proestrus
Diestrus
9 Citations (Scopus)

Priming GPCR signaling through the synergistic effect of two G proteins

Gupte, T., Malik, R. U., Sommese, R. F., Ritt, M. & Sivaramakrishnan, S., Apr 4 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 14, p. 3756-3761 6 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptors
GTP-Binding Proteins
Adrenergic Receptors
Gq-G11 GTP-Binding Protein alpha Subunits
Allosteric Site
2 Citations (Scopus)

Role of clathrin in dense core vesicle biogenesis

Sahu, B. S., Manna, P. T., Edgar, J. R., Antrobus, R., Mahata, S. K., Bartolomucci, A., Borner, G. H. H. & Robinson, M. S., Oct 1 2017, In : Molecular biology of the cell. 28, 20, p. 2676-2685 10 p.

Research output: Contribution to journalArticle

Clathrin
Secretory Vesicles
Proteins
PC12 Cells
Mass Spectrometry
11 Citations (Scopus)

Sequence-Directed Covalent Protein-DNA Linkages in a Single Step Using HUH-Tags

Lovendahl, K. N., Hayward, A. N. & Gordon, W. R., May 24 2017, In : Journal of the American Chemical Society. 139, 20, p. 7030-7035 6 p.

Research output: Contribution to journalArticle

Open Access
DNA
Fusion reactions
Proteins
Endonucleases
Single-Stranded DNA
4 Citations (Scopus)

Stochasticity in the enterococcal sex pheromone response revealed by quantitative analysis of transcription in single cells

Breuer, R. J., Bandyopadhyay, A., O’Brien, S. A., Barnes, A. M. T., Hunter, R. C., Hu, W-S. & Dunny, G. M., Jul 2017, In : PLoS genetics. 13, 7, e1006878.

Research output: Contribution to journalArticle

Open Access
Sex Attractants
sex pheromone
Pheromones
sex pheromones
stochasticity
3 Citations (Scopus)

The role of regulatory domains in maintaining autoinhibition in the multidomain kinase PKCα

Sommese, R., Ritt, M., Swanson, C. J. & Sivaramakrishnan, S., Feb 17 2017, In : Journal of Biological Chemistry. 292, 7, p. 2873-2880 8 p.

Research output: Contribution to journalArticle

Protein Kinase C
Catalytic Domain
Nucleotides
Chemical activation
Membranes
2016
2 Citations (Scopus)
Biofiltration
biofiltration
Biofilms
bait
biofilm
22 Citations (Scopus)

Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation

Vincent, L., Vang, D., Nguyen, J., Benson, B., Lei, J. & Gupta, K., Apr 30 2016, In : Haematologica. 101, 5, p. 566-577 12 p.

Research output: Contribution to journalArticle

Neurogenic Inflammation
Cannabinoid Receptors
Sickle Cell Anemia
Mast Cells
Cannabinoids
4 Citations (Scopus)

Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles

Bian, T., Autry, J. M., Casemore, D., Li, J., Thomas, D. D., He, G. & Xing, C., Dec 9 2016, In : Biochemical and Biophysical Research Communications. 481, 3-4, p. 206-211 6 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum Calcium-Transporting ATPases
Unilamellar Liposomes
Calcium
Molecules
Fusion reactions
28 Citations (Scopus)

Engineering formation of multiple recombinant Eut protein nanocompartments in E. coli

Held, M., Kolb, A., Perdue, S., Hsu, S. Y., Bloch, S. E., Quin, M. B. & Schmidt-Dannert, C., Apr 11 2016, In : Scientific reports. 6, 24359.

Research output: Contribution to journalArticle

Recombinant Proteins
Escherichia coli
Proteins
Enzymes
Ethanolamine
18 Citations (Scopus)

Glycoengineered mesenchymal stem cells as an enabling platform for two-step targeting of solid tumors

Layek, B., Sadhukha, T. & Prabha, S., May 1 2016, In : Biomaterials. 88, p. 97-109 13 p.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Tumors
Neoplasms
Nanoparticles
14 Citations (Scopus)

Heterogeneous Differentiation of Human Mesenchymal Stem Cells in 3D Extracellular Matrix Composites

Jung, J. P., Bache-Wiig, M. K., Provenzano, P. & Ogle, B. M., Jan 1 2016, In : BioResearch Open Access. 5, 1, p. 37-48 12 p.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Extracellular Matrix Proteins
Extracellular Matrix
Collagen Type I
7 Citations (Scopus)

MyTH4-FERM myosins have an ancient and conserved role in filopod formation

Petersen, K. J., Goodson, H. V., Arthur, A. L., Luxton, G. W. G., Houdusse, A., Titus, M. A. & Devreotes, P. N., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8059-E8068

Research output: Contribution to journalArticle

Myosins
Pseudopodia
Amoebozoa
Null Lymphocytes
Amoeba
1 Citation (Scopus)

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

Eckfeldt, C. E., Pomeroy, E. J., Lee, R. D. W., Hazen, K. S., Lee, L. A., Moriarity, B. S. & Largaespada, D. A., Jan 1 2016, In : Oncotarget. 7, 40, p. 65147-65156 10 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Survival
Phosphatidylinositol 3-Kinase
Proto-Oncogenes
Myeloid Cells
62 Citations (Scopus)

The DNA cytosine deaminase APOBEC3H haplotype i likely contributes to breast and lung cancer mutagenesis

Starrett, G. J., Luengas, E. M., McCann, J. L., Ebrahimi, D., Temiz, N. A., Love, R. P., Feng, Y., Adolph, M. B., Chelico, L., Law, E. K., Carpenter, M. A. & Harris, R. S., Sep 21 2016, In : Nature communications. 7, 12918.

Research output: Contribution to journalArticle

Cytosine Deaminase
mutagenesis
Mutagenesis
mutations
breast
2015
11 Citations (Scopus)

The myosin super-relaxed state is disrupted by estradiol deficiency

Colson, B. A., Petersen, K. J., Collins, B. C., Lowe, D. A. & Thomas, D. D., Jan 2 2015, In : Biochemical and Biophysical Research Communications. 456, 1, p. 151-155 5 p.

Research output: Contribution to journalArticle

Myosins
Muscle
Estradiol
Adenosine Triphosphate
Muscles
36 Citations (Scopus)

Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster

Yamanaka, N., Marques, G. & O'Connor, M. B., Nov 5 2015, In : Cell. 163, 4, p. 907-919 13 p.

Research output: Contribution to journalArticle

Steroid hormones
Ecdysone
Drosophila melanogaster
Steroids
Hormones
2014
21 Citations (Scopus)

Encapsulation in nanoparticles improves anti-cancer efficacy of carboplatin

Sadhukha, T. & Prabha, S., Jan 1 2014, In : AAPS PharmSciTech. 15, 4, p. 1029-1038 10 p.

Research output: Contribution to journalArticle

Carboplatin
nanoparticles
encapsulation
Nanoparticles
neoplasms
222 Citations (Scopus)

Intravascular staining for discrimination of vascular and tissue leukocytes

Anderson, K. G., Mayer-Barber, K., Sung, H., Beura, L. K., James, B. R., Taylor, J. J., Qunaj, L., Griffith, T. S., Vezys, V., Barber, D. L. & Masopust, D., Jan 1 2014, In : Nature Protocols. 9, 1, p. 209-222 14 p.

Research output: Contribution to journalArticle

Blood Vessels
Leukocytes
Tissue
Staining and Labeling
Lymphocytic choriomeningitis virus
11 Citations (Scopus)

Morphology, ultrastructure and functional role of antennal sensilla in off-host aggregation by the bed bug, Cimex lectularius

Olson, J. F., Moon, R. D., Kells, S. A. & Mesce, K. A., Mar 1 2014, In : Arthropod Structure and Development. 43, 2, p. 117-122 6 p.

Research output: Contribution to journalArticle

Bedbugs
Cimex lectularius
Cimicidae
Sensilla
functional role
41 Citations (Scopus)

Nano-engineered mesenchymal stem cells as targeted therapeutic carriers

Sadhukha, T., O'Brien, T. D. & Prabha, S., Dec 28 2014, In : Journal of Controlled Release. 196, p. 243-251 9 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Neoplasms
Nanoparticles
Pharmaceutical Preparations
Therapeutics
12 Citations (Scopus)

Quantitative PCR for measuring biomass of decomposer fungi in planta

Song, Z., Vail, A., Sadowsky, M. J. & Schilling, J. S., Feb 1 2014, In : Fungal Ecology. 7, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

Plantae
quantitative polymerase chain reaction
fungus
fungi
biomass
61 Citations (Scopus)

Tumor-stromal cross talk: Direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes

Thayanithy, V., Dickson, E. L., Steer, C. J., Subramanian, S. & Lou, E., Nov 1 2014, In : Translational Research. 164, 5, p. 359-365 7 p.

Research output: Contribution to journalArticle

Nanotubes
MicroRNAs
Tumors
Neoplasms
Cells

Welcome to this microscopy and microanalysis meeting, M & M 2014 in Hartford, Connecticut!

Bell, D., Sanders, M., Picard, Y., Martinez, J., Geitmann, A. & Vicenzi, E., Aug 1 2014, In : Microscopy and Microanalysis. 20, 3, p. xciv

Research output: Contribution to journalEditorial

Microanalysis
microanalysis
Microscopic examination
microscopy
2013
16 Citations (Scopus)

Electrodeposition and characterization of magnetostrictive galfenol (FeGa) thin films for use in microelectromechanical systems

Estrine, E. C., Robbins, W. P., Maqableh, M. M. & Stadler, B. J., May 7 2013, In : Journal of Applied Physics. 113, 17, 17A937.

Research output: Contribution to journalArticle

magnetostriction
electrodeposition
microelectromechanical systems
adhesion
thin films
2012
95 Citations (Scopus)

Engineered protein nano-compartments for targeted enzyme localization

Choudhary, S., Quin, M. B., Sanders, M. A., Johnson, E. T. & Schmidt-Dannert, C., Mar 12 2012, In : PloS one. 7, 3, e33342.

Research output: Contribution to journalArticle

Biocatalysis
Enzymes
enzymes
Salmonella enterica
Proteins
30 Citations (Scopus)

Relay of retrograde synaptogenic signals through axonal transport of BMP receptors

Smith, R. B., Machamer, J. B., Kim, N. C., Hays, T. S. & Marques, G., Aug 15 2012, In : Journal of cell science. 125, 16, p. 3752-3764 13 p.

Research output: Contribution to journalArticle

Bone Morphogenetic Protein Receptors
Bone Morphogenetic Proteins
Axonal Transport
Presynaptic Terminals
Axons
2010
33 Citations (Scopus)

Efficacy of local rifampin/minocycline delivery (AIGIS RX ®) to eliminate biofilm formation on implanted pacing devices in a rabbit model

Hansen, L. K., Berg, K., Johnson, D., Sanders, M. A. & Citron, M., Sep 1 2010, In : International Journal of Artificial Organs. 33, 9, p. 627-635 9 p.

Research output: Contribution to journalArticle

Minocycline
Biofilms
Rifampin
Bacteria
Rabbits
2009
17 Citations (Scopus)

Advanced laboratory techniques for sample processing and immunolabeling using microwave radiation

Ferris, A. M., Giberson, R. T., Sanders, M. A. & Day, J. R., Sep 15 2009, In : Journal of Neuroscience Methods. 182, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

Microwaves
Radiation
Immunohistochemistry
Antibodies
HeLa Cells
37 Citations (Scopus)

Multifunctional prenylated peptides for live cell analysis

Wollack, J. W., Zeliadt, N. A., Mullen, D. G., Amundson, G., Jasberg, S. G., Falkum, S., Wattenberg, E. V., Barany, G. & Distefano, M. D., Jun 3 2009, In : Journal of the American Chemical Society. 131, 21, p. 7293-7303 11 p.

Research output: Contribution to journalArticle

Peptides
Protein Prenylation
Proteins
Cells
Prenylation