Organization profile

Organization profile

Overview

The University Imaging Centers cover over 11,000 square feet of resources in three primary sites on the University of Minnesota-Twin Cities campuses. Snyder Hall on the St. Paul campus, Jackson Hall on the Minneapolis East Bank campus, and the Cancer and Cardiovascular Research Building located in the Biomedical Discovery District on the East Bank campus. The network of facilities offers instrumentation and support for light and electron microscopy, in-vivo imaging from sub-cellular to whole animal, and image analysis/visualization. The UIC is a Nikon Center of Excellence.

Operating under the direction of Mark Sanders the UIC has six full-time staff members, three part-time as well as multiple undergraduate employees that can assist in experimental design, probe and labeling selection, sample handling, tissue clearing, as well as data analysis and interpretation.

The University Imaging Centers is supported by the College of Biological Sciences and AHC/Medical School and is advised by a 13-member University-wide Advisory Panel.

Optical Systems include:

  • Laser scanning confocal microscopes with multiphoton capabilities (two)
  • Single photon confocal microscopes (six, three with spectral unmixing)
  • Super resolution Structured Illumination Microscopy (SIM)
  • Spinning disk confocal microscope
  • Total Internal Reflection Fluorescence (TIRF) Microscope
  • Fluorescent spectral meso-confocal
  • Automated widefield microscopes
  • High speed ribbon confocal
  • LightSheet

Also available at UIC facilities:

  • Spectral scans
  • Deconvolution
  • High-content widefield and confocal plate imaging
  • FRET (Fluorescence Resonance Energy Transfer)
  • FRAP (Fluorescence Recover After Photobleaching)
  • FLIM (Fluorescence Lifetime Imaging
  • SHG (Second Harmonic Generation) Imaging
  • Multi-channel live cell time-lapse
  • Small animal/bioluminescence / fluorescence (four, on with X-ray)
  • BSL-2 cabinets
  • Phosphor / fluorescence scanners for molecular biology
  • Bioluminescence and fluorescence in-vivo small animal imagers
  • microPET/CT
  • diSPIM light sheet
  • Tissue clearing
  • Large format poster printing
  • 3D printing
  • Brightfield and fluorescence slide scanning.

Fingerprint Dive into the research topics where University Imaging Centers is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Tumors Chemical Compounds
Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Cells Chemical Compounds
Chlamydomonas reinhardtii Medicine & Life Sciences
Mesenchymal Stromal Cells Medicine & Life Sciences
Nanotubes Medicine & Life Sciences
Sterol Esterase Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Profiles

No photo of Mary E Brown

Mary E Brown

Person: Researcher

No photo of Gail Celio

Gail Celio

Person: Research Support

No photo of Nadia M Kane

Nadia M Kane

Person: Research Support

Research Output 1992 2019

2 Citations (Scopus)

An integrated platform for mucin-type O-glycosylation network generation and visualization

Le, T., O’Brien, C., Gupta, U., Sousa, G., Daoutidis, P. & Hu, W-S., Jun 1 2019, In : Biotechnology and bioengineering. 116, 6, p. 1341-1354 14 p.

Research output: Contribution to journalArticle

Glycosylation
Mucins
Polysaccharides
Visualization
Enzymes

A Tissue- and Temporal-Specific Autophagic Switch Controls Drosophila Pre-metamorphic Nutritional Checkpoints

Pan, X., Neufeld, T. P. & O'Connor, M. B., Sep 9 2019, In : Current Biology. 29, 17, p. 2840-2851.e4

Research output: Contribution to journalArticle

Steroid hormones
autophagy
Autophagy
Drosophila
Switches