Projects per year
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Finished
CD133-Targeted Natural Killer Cell Therapy for Aggressive Prostate Cancer
Moriarity, B. S. (PI)
UNIVERSITY OF WISCONSIN-MADISON, U.S. DEPARTMENT OF DEFENSE
8/1/21 → 7/31/23
Project: Research project
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Severe Combined Immunodeficiency (SCID) Screening and Education
Ebens, C. (PI)
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, US Dept. of Health & Human Services HRSA
8/1/21 → 7/31/23
Project: Research project
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STUDY CHAIR: Pediatric Early Phase Clinical Trial Network (PEP-CTN) Research Base Grant(UM1CA228823)
Weigel, B. J. (PI)
PUBLIC HEALTH INSTITUTE, NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/21 → 7/31/24
Project: Research project
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Multiplex Engineered Human Lymphocytes for Therapeutic Protein Delivery
Webber, B. R. (PI), Moriarity, B. S. (CoI) & Tolar, J. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
7/7/21 → 6/30/23
Project: Research project
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Dose Optimization of Nervonic Acid-a Potential Therapy to Alleviate Disease Progression in Adrenoleukodystrophy
Kartha, R. (PI) & Lund, T. C. (CoI)
NIH NAT'L CTR FOR ADVANCING TRAN SCIENCE
7/1/21 → 5/31/24
Project: Research project
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Gene-edited tumor infiltrating lymphocytes for ovarian cancer immunotherapy
Starr, T. (PI) & Webber, B. R. (CoI)
7/1/21 → 6/30/23
Project: Research project
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CF Center Program Grant
Dunitz, J. M. (PI) & Goldfarb, S. (CoI)
7/1/21 → 6/30/24
Project: Research project
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T memory stem cells from human induced pluripotent stem cells for CAR T therapy
Allred, J. R. (PI)
AMERICAN SOCIETY OF HEMATOLOGY
7/1/21 → 6/30/22
Project: Research project
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Pharmacogenomics Clinical Training Program for Pharmacists in Rural and Underserved Areas in Minnesota
Jacobson, P. A. (PI) & Brown, J. T. (CoI)
6/30/21 → 6/30/24
Project: Research project
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TriKE, Biology, Optimization, Improved Administration, and GMP Manufacturing Support
Miller, J. S. (PI) & Felices, M. (CoI)
6/16/21 → 6/30/23
Project: Research project
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Simultaneous Targeting of Tumor and Stroma Cells to Enhance Solid Tumor CAR-T Cell Therapy
Webber, B. R. (PI)
LUMINARY THERAPEUTICS INC, NATIONAL INSTITUTES OF HEALTH (NIH)
6/1/21 → 7/31/23
Project: Research project
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Nervonic Acid-a Potential Therapy to Alleviate Disease Progression in Adrenoleukodystrophy
Kartha, R. (PI), Cloyd, J. C. (CoI) & Lund, T. C. (CoI)
5/1/21 → 10/31/23
Project: Research project
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Safety and efficacy of Nov340 delivery of SaRNA in treating MPS I disease
Whitley, C. B. (PI), Lund, T. C. (CoI), Orchard, P. J. (CoI) & Ou, L. (CoI)
5/1/21 → 4/29/23
Project: Research project
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Developing Next-Generation Cryopreservation Media for Natural Killer Cell Therapies
Hubel, A. (PI) & Felices, M. (CoI)
THE NATIONAL SCIENCE FOUNDATION
5/1/21 → 12/31/23
Project: Research project
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Brain Organoid-Derived Exosomes for Treatment of Traumatic Brain Injury
O'Brien, T. D. (PI), Crane, A. T. (CoI) & Ramachandran, S. (CoI)
4/23/21 → 6/30/24
Project: Research project
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Generation of human iPSC-derived antigen-presenting cells
Blazar, B. R. (PI)
3/5/21 → 9/30/23
Project: Research project
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Generation of myogenic progenitors from class I/II knockout / IL10-expressing TC1133 iPS cells and in vitro/in vivo characterization
Perlingeiro, R. (PI)
2/1/21 → 1/31/22
Project: Research project
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Testing Selective ROCK2 Inhibitor GB101 in Acute Grave-versus-Host Disease in Mice
Blazar, B. R. (PI)
EQUILIBRE BIOPHARMACEUTICALS CORP
1/28/21 → 12/31/21
Project: Research project
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The Myelin Disorders Biorepository Project and Global Leukodystrophy Initiative Clinical Trials Network
Gupta, A. O. (PI)
THE CHILDREN'S HOSPITAL OF PHILADELPHIA, SHIRE HUMAN GENETIC THERAPIES, INC.
12/1/20 → 12/30/23
Project: Research project
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National Adrenoleukodystrophy (ALD) Registry
Orchard, P. J. (PI) & Gupta, A. O. (CoI)
ASSOC OF PUBLIC HEALTH LABORATORIES, HRSA MATERNAL AND CHILD HEALTH (MCH)
11/26/20 → 8/31/23
Project: Research project
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Next Generation Genome Editing for RDEB
Tolar, J. (PI) & Osborn, M. J. (CoI)
11/18/20 → 11/17/21
Project: Research project
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Optimizing Editing and Delivery for Sickle Cell Disease
Osborn, M. J. (PI)
THE BROAD INSTITUTE, INC., BILL & MELINDA GATES FOUNDATION
10/28/20 → 1/31/23
Project: Research project
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Correction of Fanconi Anemia Mutations using Digital Genome Engineering
Moriarity, B. S. (PI), Wagner, J. E. (CoI) & Webber, B. R. (CoI)
10/1/20 → 3/31/23
Project: Research project
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Transposon Engineered B Cell Therapy for Hunter Syndrome
Belur, L. (PI) & Lund, T. C. (CoI)
IMMUSOFT CORPORATION, NATIONAL INSTITUTES OF HEALTH (NIH)
9/30/20 → 9/29/22
Project: Research project
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Chilled Platelet Study (CHIPS)
Zantek, N. D. (PI) & Steiner, M. E. (CoI)
WASHINGTON UNIVERSITY IN ST. LOUIS, U.S. DEPARTMENT OF DEFENSE
9/25/20 → 6/30/22
Project: Research project
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Chilled Platelet Study (CHIPS)
Cohn, C. S. (PI)
WASHINGTON UNIVERSITY IN ST. LOUIS, U.S. DEPARTMENT OF DEFENSE
9/25/20 → 6/30/22
Project: Research project
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Enhancing the University of Minnesota COVID-19 Registry for Optimal Data Contribution to the NCATS National COVID Cohort Collaborative (N3C) Repository
Johnson, S. (PI), Melton-Meaux, G. B. (CoI), Meyer, T. (CoI) & Weisdorf, D. J. (CoI)
NIH NAT'L CTR FOR ADVANCING TRAN SCIENCE
9/23/20 → 6/30/21
Project: Research project
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Skeletal Muscle Regeneration from Pluripotent Stem Cells
Perlingeiro, R. (PI)
NIH NIAMS NATL INST OF ARTHRIT
9/15/20 → 8/31/22
Project: Research project
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Data on outcomes with allogenic haematopoietic stem cell transplants in Mucopolysaccharidosis type I
Orchard, P. J. (PI), Eisengart, J. (CoI), Lund, T. C. (CoI) & Miller, B. S. (CoI)
9/9/20 → 5/6/22
Project: Research project
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NanoCol: A nanoneedle bandage for topical intracellular COL7A1 gene therapy to accelerate wound healing in recessive dystrophic epidermolysis bullosa.
Tolar, J. (PI)
9/1/20 → 8/31/22
Project: Research project
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Preventing Cognitive decline by Reducing BP Target Trial (PCOT)
Drawz, P. E. (PI) & Melton-Meaux, G. B. (CoI)
UT SOUTHWESTERN MEDICAL CENTER, NATIONAL INSTITUTES OF HEALTH (NIH)
9/1/20 → 5/14/21
Project: Research project
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A Novel Approach Combining Oncolytic Virotherapy and Dual Immune Checkpoint Blockade for Metastatic Osteosarcoma
Modiano, J. (PI), Henson, M. S. (CoI), Kim, J. H. (CoI), Vallera, D. A. (CoI) & Weigel, B. J. (CoI)
9/1/20 → 8/31/24
Project: Research project
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Passive Immunity Trial for Our Nation (PassItOn)
Cohn, C. S. (PI)
VANDERBILT UNIVERSITY MEDICAL CENTER, NIH NAT'L CTR FOR ADVANCING TRAN SCIENCE
8/18/20 → 8/31/21
Project: Research project
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Driving Natural Killer Cell Immunotherapy in the Castration Resistant Prostate Cancer Setting with Novel Tri-Specific Killer Engager Molecules
Felices, M. (PI), Miller, J. S. (CoI), Rao, A. (CoI), Ryan, C. (CoI) & Vallera, D. A. (CoI)
8/1/20 → 7/31/24
Project: Research project
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IL-15 superagonist ALT 803 maintenance therapy to prevent recurrence of advanced stage ovarian cancer
Geller, M. A. (PI) & De For, T. E. (Other Role)
8/1/20 → 7/31/22
Project: Research project
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Intraperitoneal FATE FT516 and Interleukin-2 (IL-2) with Intravenous Enoblituzumab in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Geller, M. A. (PI)
7/20/20 → 8/23/23
Project: Research project
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Chromatin Accessibility and the Convergent Oncogenic Pathways of Angiosarcomas
Kim, J. H. (PI), Moriarity, B. S. (CoI) & Webber, B. R. (CoI)
7/1/20 → 5/13/22
Project: Research project
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Multicomponent solutions for the preservation of cell therapy products
Hubel, A. (PI), Dosa, P. I. (CoI), Dutton, J. R. (CoI), McKenna, D. H. (CoI) & Ogle, B. M. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
7/1/20 → 6/30/24
Project: Research project
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Manipulating the ovarian cancer tumor microenvironment to enhance natural killer (NK) cell killing
Geller, M. A. (PI) & Felices, M. (CoI)
7/1/20 → 6/30/24
Project: Research project
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Development of novel chemokine beacons to drive targeted migration of natural killer cells towards colorectal cancer
Felices, M. (PI), Lou, E. (CoI), Miller, J. S. (CoI) & Wood, D. K. (CoI)
7/1/20 → 6/30/23
Project: Research project
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PACT III Manufacture of MSCs for the STAT trial (COVID)
McKenna, D. H. (PI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
7/1/20 → 12/31/20
Project: Research project
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RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF THE SAFETY, TOLERABILITY, AND EFFICACY OF RV521 IN THE TREATMENT OF ADULT SUBJECTS WHO HAVE UNDERGONE HEMATOPOIETIC CELL TRANSPLANTATION (HCT) WITH A DOCUMENTED UPPER RESPIRATORY TRACTINFECTION (URT)
Young, J.-A. H. (PI)
6/24/20 → 1/31/24
Project: Research project
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Bcl-2 protein Noxa in human T cell metabolism and differentiation
Kelekar, A. (PI), Moriarity, B. S. (CoI), Pennell, C. A. (CoI) & Webber, B. R. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
6/18/20 → 5/31/23
Project: Research project
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A novel autoinflammatory skin disease in a patient with mutations in alpha-T-catenin
Binstadt, B. A. (PI) & Tolar, J. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
6/17/20 → 5/31/23
Project: Research project
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Targeted Clinical Research to Address Select Viral Infections
Young, J.-A. H. (PI)
FRED HUTCHINSON CANCER CENTER, NATIONAL INSTITUTES OF HEALTH (NIH)
6/16/20 → 6/15/23
Project: Research project
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CRISPR/Cas9 Cellular Engineering for the Creation of Coagulation Factor-Based Resuscitation Fluid to Combat Hemorrhage and Coagulopathy
Osborn, M. J. (PI)
THE GENEVA FOUNDATION, U.S. DEPARTMENT OF DEFENSE
6/16/20 → 6/15/23
Project: Research project
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Engineering Cells for Transplant in Pigs
Webber, B. R. (PI) & Moriarity, B. S. (CoI)
5/31/20 → 6/10/22
Project: Research project
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Length of Storage of Red Blood Cell Units as a Risk Factor for Hospital-Acquired Infections
Steiner, M. E. (PI)
MCGILL UNIVERSITY, CANADIAN INSTITUTES OF HEALTH RESEARCH
5/4/20 → 3/31/23
Project: Research project