Therapeutics Discovery and Development Institute

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Prodrugs Medicine & Life Sciences
Assays Chemical Compounds
Polyethylene glycols Chemical Compounds
Gases Chemical Compounds
Opioid Analgesics Medicine & Life Sciences
Telomerase Medicine & Life Sciences
Carboxylic Acids Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences

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Projects 2010 2022

Regenerating New Drug Leads for Schistosomasis

Dosa, P. I. & Hawkinson, J.

Medical College of Wisconsin


Project: Research project

Pharmaceutical Preparations
Bile Acids and Salts

Research Output 1996 2017

17 Citations

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

Dahlin, J. L., Nelson, K., Strasser, J. M., Barsyte-Lovejoy, D., Szewczyk, M. M., Organ, S., Cuellar, M. E., Singh, G., Shrimp, J. H., Nguyen, N., Meier, J. L., Arrowsmith, C. H., Brown, P. J., Baell, J. B. & Walters, M. A., Dec 1 2017, In : Nature communications. 8, 1, 1527.

Research output: Contribution to journalArticle

Histone Acetyltransferases
13 Citations

BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen

Ayoub, A. M., Hawk, L. M. L., Herzig, R. J., Jiang, J., Wisniewski, A. J., Gee, C. T., Zhao, P., Zhu, J. Y., Berndt, N., Offei-Addo, N. K., Scott, T. G., Qi, J., Bradner, J. E., Ward, T. R., Schönbrunn, E., Georg, G. I. & Pomerantz, W. C. K., Jun 22 2017, In : Journal of Medicinal Chemistry. 60, 12, p. 4805-4817 13 p.

Research output: Contribution to journalArticle

Fluorescence Polarization
Structure-Activity Relationship
6 Citations

Curcumin May (Not) Defy Science

Nelson, K. M., Dahlin, J. L., Bisson, J., Graham, J., Pauli, G. F. & Walters, M. A., May 11 2017, In : ACS Medicinal Chemistry Letters. 8, 5, p. 467-470 4 p.

Research output: Contribution to journalLetter