Therapeutics Discovery and Development Institute

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Neoplasms Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Proteins Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Gases Chemical Compounds
Prodrugs Medicine & Life Sciences
Throughput Chemical Compounds

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Projects 2010 2022

Bile Acids and Salts
Infection
tartaric acid
phenserine

Research Output 1996 2017

1 Citations

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

Dahlin, J. L., Nelson, K. M., Strasser, J. M., Barsyte-Lovejoy, D., Szewczyk, M. M., Organ, S., Cuellar, M., Singh, G., Shrimp, J. H., Nguyen, N., Meier, J. L., Arrowsmith, C. H., Brown, P. J., Baell, J. B. & Walters, M. A. Dec 1 2017 In : Nature Communications. 8, 1, 1527

Research output: Research - peer-reviewArticle

liabilities
inhibitors
counters
interference
Histone Acetyltransferases
1 Citations

BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen

Ayoub, A. M., Hawk, L. M. L., Herzig, R. J., Jiang, J., Wisniewski, A. J., Gee, C. T., Zhao, P., Zhu, J. Y., Berndt, N., Offei-Addo, N. K., Scott, T. G., Qi, J., Bradner, J. E., Ward, T. R., Schönbrunn, E., Georg, G. I. & Pomerantz, W. C. K. Jun 22 2017 In : Journal of Medicinal Chemistry. 60, 12, p. 4805-4817 13 p.

Research output: Research - peer-reviewArticle

Ligands
Fluorescence Polarization
Uracil
Structure-Activity Relationship
Contraception
2 Citations

Curcumin May (Not) Defy Science

Nelson, K. M., Dahlin, J. L., Bisson, J., Graham, J., Pauli, G. F. & Walters, M. A. May 11 2017 In : ACS Medicinal Chemistry Letters. 8, 5, p. 467-470 4 p.

Research output: Research - peer-reviewLetter

Liquid phase sintering
Curcumin