Therapeutics Discovery and Development Institute

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Prodrugs Medicine & Life Sciences
Assays Chemical Compounds
Polyethylene glycols Chemical Compounds
Gases Chemical Compounds
Opioid Analgesics Medicine & Life Sciences
Telomerase Medicine & Life Sciences
Carboxylic Acids Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences

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Projects 2010 2022

Bile Acids and Salts
Infection
tartaric acid
phenserine

Research Output 1996 2017

3 Citations

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

Dahlin, J. L., Nelson, K. M., Strasser, J. M., Barsyte-Lovejoy, D., Szewczyk, M. M., Organ, S., Cuellar, M., Singh, G., Shrimp, J. H., Nguyen, N., Meier, J. L., Arrowsmith, C. H., Brown, P. J., Baell, J. B. & Walters, M. A. Dec 1 2017 In : Nature Communications. 8, 1, 1527

Research output: Contribution to journalArticle

liabilities
Histone Acetyltransferases
inhibitors
Assays
counters
5 Citations

BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen

Ayoub, A. M., Hawk, L. M. L., Herzig, R. J., Jiang, J., Wisniewski, A. J., Gee, C. T., Zhao, P., Zhu, J. Y., Berndt, N., Offei-Addo, N. K., Scott, T. G., Qi, J., Bradner, J. E., Ward, T. R., Schönbrunn, E., Georg, G. I. & Pomerantz, W. C. K. Jun 22 2017 In : Journal of Medicinal Chemistry. 60, 12, p. 4805-4817 13 p.

Research output: Contribution to journalArticle

Ligands
Fluorescence Polarization
Uracil
Structure-Activity Relationship
Contraception
4 Citations

Curcumin May (Not) Defy Science

Nelson, K. M., Dahlin, J. L., Bisson, J., Graham, J., Pauli, G. F. & Walters, M. A. May 11 2017 In : ACS Medicinal Chemistry Letters. 8, 5, p. 467-470 4 p.

Research output: Contribution to journalLetter

Liquid phase sintering
Curcumin