Pharmacy Research and Graduate Education

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Muscarinic Receptors Medicine & Life Sciences
N-Methylscopolamine Medicine & Life Sciences
Carbachol Medicine & Life Sciences
Neuroblastoma Medicine & Life Sciences
Cyclic GMP Medicine & Life Sciences
Muscarinic Antagonists Medicine & Life Sciences
Brain Medicine & Life Sciences
Agmatine Medicine & Life Sciences

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No photo of Esam E El-Fakahany
No photo of Carolyn A Fairbanks

Carolyn A Fairbanks


Projects 1982 2023

Research Output 1979 2018

Role of membrane cholesterol in differential sensitivity of muscarinic receptor subtypes to persistently bound xanomeline

Randáková, A., Dolejší, E., Rudajev, V., Zimčík, P., Doležal, V., El-Fakahany, E. E. & Jakubík, J., May 1 2018, In : Neuropharmacology. 133, p. 129-144 16 p.

Research output: Contribution to journalArticle

Muscarinic Receptors
2 Citations

Binding of N-methylscopolamine to the extracellular domain of muscarinic acetylcholine receptors

Jakubík, J., Randáková, A., Zimčík, P., El-Fakahany, E. E. & Doležal, V., Jan 16 2017, In : Scientific reports. 7, 40381.

Research output: Contribution to journalArticle

Muscarinic Receptors
Allosteric Site
Binding Sites
Quinuclidinyl Benzilate
2 Citations

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B. & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In : Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System