Projects per year
Organization profile
Organization profile
The N. Bud Grossman Center for Memory Research and Care is a tripartite endeavor encompassing basic, translational, and clinical research on memory disorders. Our goal is to relieve the suffering caused by Alzheimer's disease. We are working towards safe and affordable prevention strategies and comprehensive care and support for people with memory problems and their families. In order to achieve this goal, we have brought together scientists, physicians and health care workers.We are one of four centers within the Institute for Translational Neuroscience (ITN), administered within the Medical School which is a division of the Academic Health Center at the University of Minnesota. The center members are drawn from the Departments of Neurology, Neuroscience, and Psychiatry. Our center has strong ties to the Minneapolis Veterans Affairs Health System, Geriatric Research, Education and Clinical Center (VA GRECC) where some faculty have joint appointments and some of our research is performed.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Profiles
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Peng Liu
- Neurology - Assistant Professor
- N. Bud Grossman Center for Memory Research and Care
Person: Faculty
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Structure and toxicity of a specific tau oligomer related to dementia
Liu, P. (PI), Ashe, K. H. (CoI) & Liao, D. (CoI)
8/1/24 → 7/31/27
Project: Research project
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Characterization of ApoE4 Induced Phospholipid Dysregulation in AD Pathogenesis
Cai, D. (PI)
NIH NAT'L INSTITUTE ON AGING (NIA)
4/1/24 → 3/31/26
Project: Research project
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Prodrugs of potent and selective protease inhibitors as tauopathy therapeutics
Ashe, K. H. (PI), Walters, M. A. (CoI) & Wong, H. L. (CoI)
MYRIEL, INC., NATIONAL INSTITUTES OF HEALTH (NIH)
9/20/23 → 8/31/25
Project: Research project
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Aβ∗56 is a stable oligomer that impairs memory function in mice
Liu, P., Lapcinski, I. P., Hlynialuk, C. J. W., Steuer, E. L., Loude, T. J., Shapiro, S. L., Kemper, L. J. & Ashe, K. H., Mar 15 2024, In: iScience. 27, 3, 109239.Research output: Contribution to journal › Article › peer-review
Open Access -
Repurposing non-pharmacological interventions for Alzheimer's disease through link prediction on biomedical literature
Xiao, Y., Hou, Y., Zhou, H., Diallo, G., Fiszman, M., Wolfson, J., Zhou, L., Kilicoglu, H., Chen, Y., Su, C., Xu, H., Mantyh, W. G. & Zhang, R., Dec 2024, In: Scientific reports. 14, 1, 8693.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Retraction Note: A specific amyloid-β protein assembly in the brain impairs memory (Nature, (2006), 440, 7082, (352-357), 10.1038/nature04533)
Lesné, S., Koh, M. T., Kotilinek, L., Kayed, R., Glabe, C. G., Yang, A., Gallagher, M. & Ashe, K. H., Jul 4 2024, In: Nature. 631, 8019, p. 240 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations