Research Output

2005

DJ-1, a novel regulator of the tumor suppressor PTEN

Kim, R. H., Peters, M., Jang, Y., Shi, W., Pintilie, M., Fletcher, G. C., DeLuca, C., Liepa, J., Zhou, L., Snow, B., Binari, R. C., Manoukian, A. S., Bray, M. R., Liu, F. F., Tsao, M. S. & Mak, T. W., Mar 2005, In : Cancer Cell. 7, 3, p. 263-273 11 p.

Research output: Contribution to journalArticle

423 Scopus citations

Microbial regulation of intestinal radiosensitivity

Crawford, P. A. & Gordon, J. I., Sep 13 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13254-13259 6 p.

Research output: Contribution to journalArticle

116 Scopus citations

Specific ablation of the apoptotic functions of cytochrome c reveals a differential requirement for cytochrome c and Apaf-1 in apoptosis

Hao, Z., Duncan, G. S., Chang, C. C., Elia, A., Fang, M., Wakeham, A., Okada, H., Calzascia, T., Jang, Y., You-Ten, A., Yeh, W. C., Ohashi, P., Wang, X. & Mak, T. W., May 20 2005, In : Cell. 121, 4, p. 579-591 13 p.

Research output: Contribution to journalArticle

209 Scopus citations
2004

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

You, H., Jang, Y. J., You-Ten, A. I., Okada, H., Liepa, J., Wakeham, A., Zaugg, K. & Mak, T. W., Sep 28 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 39, p. 14057-14062 6 p.

Research output: Contribution to journalArticle

99 Scopus citations
2001

Regulation of PTEN transcription by p53

Stambolic, V., MacPherson, D., Sas, D., Lin, Y., Snow, B., Jang, Y., Benchimol, S. & Mak, T. W., Jan 1 2001, In : Molecular Cell. 8, 2, p. 317-325 9 p.

Research output: Contribution to journalArticle

671 Scopus citations

RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons

Enomoto, H., Crawford, P. A., Gorodinsky, A., Heuckeroth, R. O., Johnson, E. M. & Milbrandt, J., Nov 20 2001, In : Development. 128, 20, p. 3963-3974 12 p.

Research output: Contribution to journalArticle

219 Scopus citations

The DEAD box protein DP103 is a regulator of steroidogenic factor-1

Ou, Q., Mouillet, J. F., Yan, X., Dorn, C., Crawford, P. A. & Sadovsky, Y., 2001, In : Molecular Endocrinology. 15, 1, p. 69-79 11 p.

Research output: Contribution to journalArticle

73 Scopus citations
2000

Steroidogenic factor 1 is a monomeric orphan, but does not work alone

Ou, Q., Mouillet, J. F., Yan, X., Dorn, C., Crawford, P. A. & Sadovsky, Y., Jan 1 2000, In : Endocrine Research. 26, 4, p. 1003-1004 2 p.

Research output: Contribution to journalArticle

1999

Activation of luteinizing hormone β gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1

Dorn, C., Ou, Q., Svaren, J., Crawford, P. A. & Sadovsky, Y., May 14 1999, In : Journal of Biological Chemistry. 274, 20, p. 13870-13876 7 p.

Research output: Contribution to journalArticle

145 Scopus citations

Thermodynamics and kinetics of a folded-folded' transition at valine-9 of a GCN4-like leucine zipper

D'Avignon, D. A., Bretthorst, G. L., Holtzer, M. E. & Holtzer, A., 1999, In : Biophysical journal. 76, 5, p. 2752-2759 8 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
1998

Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1

Crawford, P. A., Dorn, C., Sadovsky, Y. & Milbrandt, J., May 1998, In : Molecular and cellular biology. 18, 5, p. 2949-2956 8 p.

Research output: Contribution to journalArticle

275 Scopus citations
1997

Characterization of the promoter of SF-1, an orphan nuclear receptor required for adrenal and gonadal development

Woodson, K. G., Crawford, P. A., Sadovsky, Y. & Milbrandt, J., Jan 1 1997, In : Molecular Endocrinology. 11, 2, p. 117-126 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage

Crawford, P. A., Sadovsky, Y. & Milbrandt, J., Jul 1997, In : Molecular and cellular biology. 17, 7, p. 3997-4006 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

Role of steroidogenic-factor 1 in basal and 3',5'-cyclic adenosine monophosphate-mediated regulation of cytochrome P450 side-chain cleavage enzyme in the mouse

Chau, Y. M., Crawford, P. A., Woodson, K. G., Polish, J. A., Olson, L. M. & Sadovsky, Y., Oct 1 1997, In : Biology of reproduction. 57, 4, p. 765-771 7 p.

Research output: Contribution to journalArticle

58 Scopus citations

The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1

Crawford, P. A., Polish, J. A., Ganpule, G. & Sadovsky, Y., Jan 1 1997, In : Molecular Endocrinology. 11, 11, p. 1626-1635 10 p.

Research output: Contribution to journalArticle

91 Scopus citations
1995

Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice

Crawford, P. A., Sadovsky, Y., Woodson, K., Lee, S. L. & Milbrandt, J., Aug 1995, In : Molecular and cellular biology. 15, 8, p. 4331-4336 6 p.

Research output: Contribution to journalArticle

Open Access
131 Scopus citations

Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids

Sadovsky, Y., Crawford, P. A., Woodson, K. G., Polish, J. A., Clements, M. A., Tourtellotte, L. M., Simburger, K. & Milbrandt, J., Dec 6 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 24, p. 10939-10943 5 p.

Research output: Contribution to journalArticle

357 Scopus citations

Nuclear Magnetic Resonance Studies Demonstrate Differences in the Interaction of Retinoic Acid with Two Highly Homologous Cellular Retinoic Acid Binding Proteins

Norris, A. W., Rong, D., d'Avignon, D. A., Rosenberger, M., Tasaki, K. & Li, E., Nov 1995, In : Biochemistry. 34, 47, p. 15564-15573 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Stability-indicating proton nuclear magnetic resonance spectroscopic method for determination of S-adenosyl-L-methionine in tablets.

Revelle, L. K., d'Avignon, D. A., Reepmeyer, J. C. & Zerfing, R. C., 1995, In : Journal of AOAC International. 78, 2, p. 353-358 6 p.

Research output: Contribution to journalArticle

13 Scopus citations
1992
Open Access
39 Scopus citations
1988

Correlation between the anaesthetic effect of halothane and saturable binding in brain

Evers, A. S., Berkowitz, B. A. & D'Avignon, D. A., 1988, In : Nature. 328, 6126, p. 157-160 4 p.

Research output: Contribution to journalArticle

67 Scopus citations
1981

The 14N and 2H nuclear quadrupole resonance spectra of anthranilic acid

D'Avignon, D. A. & Brown, T. L., 1981, In : Journal of physical chemistry. 85, 26, p. 4073-4079 7 p.

Research output: Contribution to journalArticle

17 Scopus citations