Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Steroidogenic Factor 1 Medicine & Life Sciences
Ketone Bodies Medicine & Life Sciences
Liver Medicine & Life Sciences
Glucose Medicine & Life Sciences
Gluconeogenesis Medicine & Life Sciences
Carbohydrate-Restricted Diet Medicine & Life Sciences
glyphosate Medicine & Life Sciences
Ketogenic Diet Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2017 2020

Homeostasis
Carbon

Research Output 1981 2019

Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis

Puchalska, P., Martin, S. E., Huang, X., Lengfeld, J. E., Daniel, B., Graham, M. J., Han, X., Nagy, L., Patti, G. J. & Crawford, P., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 383-398.e7

Research output: Contribution to journalArticle

Hepatocytes
Fibrosis
Macrophages
Coenzyme A-Transferases
Keto Acids

The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense

Horton, J. L., Davidson, M. T., Kurishima, C., Vega, R. B., Powers, J. C., Matsuura, T. R., Petucci, C., Lewandowski, E. D., Crawford, P., Muoio, D. M., Recchia, F. A. & Kelly, D. P., Feb 21 2019, In : JCI insight. 4, 4

Research output: Contribution to journalArticle

Open Access
Physiological Stress
3-Hydroxybutyric Acid
Ketone Bodies
Heart Failure
Ketones
1 Citation (Scopus)

Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates

Hughey, C., Trefts, E., Bracy, D. P., James, F. D., Patrick Donahue, E. & Wasserman, D. H., Jan 1 2018, In : Journal of Biological Chemistry. 293, 30, p. 11944-11954 11 p.

Research output: Contribution to journalArticle

Glycine N-Methyltransferase
Carbon Cycle
Gluconeogenesis
S-Adenosylmethionine
Methionine