Research Output 1977 2019

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2019
Telomere Shortening
Ligases
DNA Ligases
Telomere-Binding Proteins
Chromosomes
1 Citation (Scopus)

Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin

Cleal, K., Jones, R. E., Grimstead, J. W., Hendrickson, E. A. & Baird, D. M., May 1 2019, In : Genome Research. 29, 5, p. 737-749 13 p.

Research output: Contribution to journalArticle

Open Access
Telomere
Genome
Genomic Instability
Sequence Analysis
Chromothripsis
2 Citations (Scopus)
DNA Ligases
Chromatids
Telomere
Cell Cycle
Ligases
2018
1 Citation (Scopus)
Polycomb Repressive Complex 2
Histones
Drosophila
Genes
Diptera
2 Citations (Scopus)

CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length

Gu, P., Jia, S., Takasugi, T., Smith, E., Nandakumar, J., Hendrickson, E. A. & Chang, S., Aug 1 2018, In : Aging cell. 17, 4, e12783.

Research output: Contribution to journalArticle

Telomerase
Telomere
Mutation
DNA
Clustered Regularly Interspaced Short Palindromic Repeats
4 Citations (Scopus)
Flap Endonucleases
Genomic Instability
Proliferating Cell Nuclear Antigen
DNA Damage
Hypersensitivity
1 Citation (Scopus)
Single Nucleotide Polymorphism
Enzymes
Genome-Wide Association Study
Juvenile Arthritis
Carrier Proteins
7 Citations (Scopus)

Identification of diverse target RNAs that are functionally regulated by human pumilio proteins

Bohn, J. A., Van Etten, J. L., Schagat, T. L., Bowman, B. M., McEachin, R. C., Freddolino, P. L. & Goldstrohm, A., Jan 1 2018, In : Nucleic acids research. 46, 1, p. 362-386 25 p.

Research output: Contribution to journalArticle

Open Access
RNA
Response Elements
Untranslated RNA
Messenger RNA
RNA-Binding Proteins
2 Citations (Scopus)

PARP1 is required for preserving telomeric integrity but is dispensable for A-NHEJ

Harvey, A., Mielke, N., Grimstead, J. W., Jones, R. E., Nguyen, T., Mueller, M., Baird, D. M. & Hendrickson, E. A., Oct 1 2018, In : Oncotarget. 9, 78, p. 34821-34837 17 p.

Research output: Contribution to journalArticle

Telomere
Breast Neoplasms
Genetic Markers
Ovarian Neoplasms
DNA Damage
Telomere
Plasma Cell Leukemia
Cell Line
Genomic Instability
Telomerase
4 Citations (Scopus)
Ribonucleases
Exoribonucleases
Catalytic Domain
Messenger RNA
nocturnin
2017
5 Citations (Scopus)
Fanconi Anemia
Fanconi Anemia Complementation Group D2 Protein
Chromatin
Fanconi Anemia Complementation Group Proteins
Null Lymphocytes
1 Citation (Scopus)
Virus Integration
Repair
Radiation
Genes
Annealing
20 Citations (Scopus)

Mechanisms of precise genome editing using oligonucleotide donors

Kan, Y., Ruis, B. L., Takasugi, T. & Hendrickson, E. A., Jul 1 2017, In : Genome Research. 27, 7, p. 1099-1111 13 p.

Research output: Contribution to journalArticle

Open Access
Oligonucleotides
Oligodeoxyribonucleotides
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Conversion
Deoxyribonuclease I
11 Citations (Scopus)

Rapid DNA replication origin licensing protects stem cell pluripotency

Matson, J. P., Dumitru, R., Coryell, P., Baxley, R. M., Chen, W., Twaroski, K., Webber, B. R., Tolar, J., Bielinsky, A. K., Purvis, J. E. & Cook, J. G., Nov 17 2017, In : eLife. 6, e30473.

Research output: Contribution to journalArticle

Replication Origin
Licensure
Stem cells
DNA Replication
Stem Cells
2016
44 Citations (Scopus)
Initiator Codon
Poisons
Reading Frames
Proteins
Nucleotides
1 Citation (Scopus)
Ubiquitination
Lysine
Saccharomyces cerevisiae
Proliferating Cell Nuclear Antigen
Machinery
20 Citations (Scopus)

Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells

Alotaibi, M., Sharma, K., Saleh, T., Povirk, L. F., Hendrickson, E. A. & Gewirtz, D. A., Mar 1 2016, In : Radiation Research. 185, 3, p. 229-245 17 p.

Research output: Contribution to journalArticle

DNA Repair-Deficiency Disorders
Autophagy
tumors
deoxyribonucleic acid
recovery
7 Citations (Scopus)

Restoration of ATM expression in DNA-PKcs-deficient cells inhibits signal end joining

Neal, J. A., Xu, Y., Abe, M., Hendrickson, E. A. & Meek, K., Apr 1 2016, In : Journal of Immunology. 196, 7, p. 3032-3042 11 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Catalytic Domain
V(D)J Recombination
Cell Line
Cultured Cells
8 Citations (Scopus)
Minichromosome Maintenance Proteins
M Phase Cell Cycle Checkpoints
Ligases
Methyl Methanesulfonate
Protein Deficiency
2015
1 Citation (Scopus)

Alternative end joining, clonal evolution, and escape from a telomere-driven crisis

Hendrickson, E. A. & Baird, D. M., Jan 2 2015, In : Molecular and Cellular Oncology. 2, 1, e975623.

Research output: Contribution to journalArticle

Clonal Evolution
Telomere
Genomic Instability
Neoplasms
50 Citations (Scopus)

ATRX represses alternative lengthening of telomeres

Napier, C. E., Huschtscha, L. I., Harvey, A., Bower, K., Noble, J. R., Hendrickson, E. A. & Reddel, R. R., Jan 1 2015, In : Oncotarget. 6, 18, p. 16543-16558 16 p.

Research output: Contribution to journalArticle

Telomere Homeostasis
Telomerase
Telomere Shortening
Chromatin Assembly and Disassembly
Homologous Recombination
26 Citations (Scopus)

A versatile reporter system for CRISPR-mediated chromosomal rearrangements

Li, Y., Park, A. I., Mou, H., Colpan, C., Bizhanova, A., Akama-Garren, E., Joshi, N., Hendrickson, E. A., Feldser, D., Yin, H., Anderson, D. G., Jacks, T., Weng, Z. & Xue, W., May 28 2015, In : Genome biology. 16, 1, 111.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
DNA Breaks
Gene Rearrangement
Nucleotides
Liver
20 Citations (Scopus)

Cockayne syndrome group B protein regulates DNA double-strand break repair and checkpoint activation

Batenburg, N. L., Thompson, E. L., Hendrickson, E. A. & Zhu, X. D., May 12 2015, In : EMBO Journal. 34, 10, p. 1399-1416 18 p.

Research output: Contribution to journalArticle

Cockayne Syndrome
Double-Stranded DNA Breaks
Chromatin
Repair
Chemical activation
116 Citations (Scopus)

DNA2 drives processing and restart of reversed replication forks in human cells

Thangavel, S., Berti, M., Levikova, M., Pinto, C., Gomathinayagam, S., Vujanovic, M., Zellweger, R., Moore, H., Lee, E. H., Hendrickson, E. A., Cejka, P., Stewart, S., Lopes, M. & Vindigni, A., Jan 1 2015, In : Journal of Cell Biology. 208, 5, p. 545-562 18 p.

Research output: Contribution to journalArticle

DNA Replication
Homologous Recombination
DNA Damage
Adenosine Triphosphatases
Genome
8 Citations (Scopus)

EIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells

Avdulov, S. V., Herrera, J., Smith, K., Peterson, M., Gomez-Garcia, J. R., Beadnell, T. C., Schwertfeger, K., Benyumov, A., Manivel, J. C., Li, S., Bielinsky, A. K., Yee, D., Bitterman, P. B. & Polunovsky, V. A., Feb 15 2015, In : Cancer Research. 75, 4, p. 687-697 11 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4E
Breast
Stem Cells
DNA Replication
Lactation
33 Citations (Scopus)

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2

Castella, M., Jacquemont, C., Thompson, E. L., Yeo, J. E., Cheung, R. S., Huang, J. W., Sobeck, A., Hendrickson, E. A. & Taniguchi, T., Jan 1 2015, In : PLoS Genetics. 11, 10, e1005563.

Research output: Contribution to journalArticle

Fanconi Anemia
anemia
DNA damage
DNA Damage
DNA
26 Citations (Scopus)
Ligases
DNA Repair
Ligation
DNA
In Vitro Techniques
2014
142 Citations (Scopus)

Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining

Ghezraoui, H., Piganeau, M., Renouf, B., Renaud, J. B., Sallmyr, A., Ruis, B. L., Oh, S., Tomkinson, A. E., Hendrickson, E. A., Giovannangeli, C., Jasin, M. & Brunet, E., Sep 18 2014, In : Molecular Cell. 55, 6, p. 829-842 14 p.

Research output: Contribution to journalArticle

Genetic Translocation
Clustered Regularly Interspaced Short Palindromic Repeats
Neoplasms
Carcinogenesis
Chromosomes
45 Citations (Scopus)

CtIP mediates replication fork recovery in a FANCD2-regulated manner

Yeo, J. E., Lee, E. H., Hendrickson, E. A. & Sobeck, A., Jan 1 2014, In : Human Molecular Genetics. 23, 14, p. 3695-3705 11 p., ddu078.

Research output: Contribution to journalArticle

Fanconi Anemia
Proteins
Recombinational DNA Repair
Fanconi Anemia Complementation Group D2 Protein
DNA Repair-Deficiency Disorders
10 Citations (Scopus)

Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity

Smith, S., Fox, J., Mejia, M., Ruangpradit, W., Saberi, A., Kim, S., Choi, Y., Oh, S., Wang, Y., Choi, K., Li, L., Hendrickson, E. A., Takeda, S., Muller, M. & Myung, K., Jan 23 2014, In : PloS one. 9, 1, e87203.

Research output: Contribution to journalArticle

histone deacetylase
Histone Deacetylase Inhibitors
DNA repair
DNA Repair
Repair
15 Citations (Scopus)
Mutagenesis
Ubiquitination
DNA
Proliferating Cell Nuclear Antigen
Alleles
37 Citations (Scopus)

Preventing over-resection by DNA2 helicase/nuclease suppresses repair defects in Fanconi anemia cells

Karanja, K., Lee, E. H., Hendrickson, E. A. & Campbell, J. L., May 15 2014, In : Cell Cycle. 13, 10, p. 1540-1550 11 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Formaldehyde
Cisplatin
DNA
Ficusin
29 Citations (Scopus)

The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining

Waters, C. A., Strande, N. T., Pryor, J. M., Strom, C. N., Mieczkowski, P., Burkhalter, M. D., Oh, S., Qaqish, B. F., Moore, D. T., Hendrickson, E. A. & Ramsden, D. A., Jul 3 2014, In : Nature Communications. 5, 4286.

Research output: Contribution to journalArticle

Joining
Ligation
bypasses
Chromosome Breakage
Processing
27 Citations (Scopus)
Gene Targeting
gene targeting
somatic cells
targeting
homologous recombination
18 Citations (Scopus)

The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage

Alver, R. C., Zhang, T., Josephrajan, A., Fultz, B. L., Hendrix, C. J., Das-Bradoo, S. & Bielinsky, A. K., Jan 1 2014, In : Nucleic acids research. 42, 13, p. 8389-8404 16 p.

Research output: Contribution to journalArticle

Ultraviolet Rays
DNA Replication
DNA Damage
Minichromosome Maintenance Proteins
Chromosome Breakage
2013
16 Citations (Scopus)
S Phase
DNA Damage
Cell Cycle
DNA
Ubiquitin-Protein Ligases
34 Citations (Scopus)
Telomere
Ligases
Genetic Recombination
Chromosomes
Cell Line
12 Citations (Scopus)
Minichromosome Maintenance Proteins
DNA Replication
proteins
Two-Hybrid System Techniques
Mutation
50 Citations (Scopus)
Aurora Kinases
DNA Damage
Growth
Pharmaceutical Preparations
Neoplasms
2012
32 Citations (Scopus)
DNA-(Apurinic or Apyrimidinic Site) Lyase
Joining
Ligation
Chromosome Breakage
DNA
44 Citations (Scopus)

The HSV-1 Exonuclease, UL12, Stimulates Recombination by a Single Strand Annealing Mechanism

Schumacher, A. J., Mohni, K. N., Kan, Y., Hendrickson, E. A., Stark, J. M. & Weller, S. K., Aug 1 2012, In : PLoS Pathogens. 8, 8, e1002862.

Research output: Contribution to journalArticle

Exonucleases
Human Herpesvirus 1
Genetic Recombination
DNA Replication
Bacteriophage T4
2011
13 Citations (Scopus)
Zinc Fingers
Androgen Receptors
Carrier Proteins
Androgens
Prostatic Neoplasms
2010
14 Citations (Scopus)
Mycobacterium tuberculosis
DNA
Proteins
proteins
Open Reading Frames
154 Citations (Scopus)
Double-Stranded DNA Breaks
somatic cells
repair
DNA
Null Lymphocytes
30 Citations (Scopus)
Mitochondria
Cardiolipins
cardiolipins
mitochondria
cytochrome c
64 Citations (Scopus)
Immune system
Immune System
Phosphotransferases
Neoplasms
Genetic Models
2009
3 Citations (Scopus)

Interferon regulatory factors (IRFs) repress transcription of the chicken ovalbumin gene

Dougherty, D. C., Park, H. M. & Sanders, M. M., Jun 15 2009, In : Gene. 439, 1-2, p. 63-70 8 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factors
Ovalbumin
Chickens
Response Elements
Interferons
99 Citations (Scopus)

Ku86 represses lethal telomere deletion events in human somatic cells

Wang, Y., Ghosh, G. & Hendrickson, E. A., Jul 28 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 30, p. 12430-12435 6 p.

Research output: Contribution to journalArticle

Telomere
Double-Stranded DNA Breaks
Genetic Recombination
Maintenance
Bacteria
17 Citations (Scopus)
zinc finger motif
Adiposity
adiposity
Nutrition
Zinc