Research Output 1988 2019

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Review article
2018
15 Citations (Scopus)

APOBEC Enzymes as Targets for Virus and Cancer Therapy

Olson, M. E., Harris, R. & Harki, D. A., Jan 18 2018, In : Cell Chemical Biology. 25, 1, p. 36-49 14 p.

Research output: Contribution to journalReview article

Viruses
Mutagenesis
Uracil
Genes
Cytosine
7 Citations (Scopus)

Calprotectin and the Initiation and Progression of Head and Neck Cancer

Argyris, P., Slama, Z. M., Ross, K. F., Khammanivong, A. & Herzberg, M. C., Jun 1 2018, In : Journal of dental research. 97, 6, p. 674-682 9 p.

Research output: Contribution to journalReview article

Open Access
Leukocyte L1 Antigen Complex
Head and Neck Neoplasms
Neoplasms
Carcinogenesis
Neck
16 Citations (Scopus)

Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

Venkatesan, S., Rosenthal, R., Kanu, N., McGranahan, N., Bartek, J., Quezada, S. A., Hare, J., Harris, R. & Swanton, C., Mar 1 2018, In : Annals of Oncology. 29, 3, p. 563-572 10 p.

Research output: Contribution to journalReview article

Drug Resistance
Mutagenesis
HIV
Virology
Neoplasms
2016
11 Citations (Scopus)

Evolutionary Paradigms from Ancient and Ongoing Conflicts between the Lentiviral Vif Protein and Mammalian APOBEC3 Enzymes

Harris, R. & Anderson, B. D., Dec 1 2016, In : PLoS Pathogens. 12, 12, e1005958.

Research output: Contribution to journalReview article

2015
85 Citations (Scopus)

Altered calcium signaling in cancer cells

Stewart, T. A., Yapa, K. T. D. S. & Monteith, G. R., Oct 10 2015, In : Biochimica et Biophysica Acta - Biomembranes. 1848, 10, p. 2502-2511 10 p.

Research output: Contribution to journalReview article

Calcium Signaling
Cells
Calcium
Neoplasms
Membrane Transport Proteins
2014
140 Citations (Scopus)

Targeting EMT in cancer: Opportunities for pharmacological intervention

Davis, F. M., Stewart, T. A., Thompson, E. W. & Monteith, G. R., Jan 1 2014, In : Trends in Pharmacological Sciences. 35, 9, p. 479-488 10 p.

Research output: Contribution to journalReview article

Epithelial-Mesenchymal Transition
Cells
Pharmacology
Stem cells
Tumors
2010
140 Citations (Scopus)

Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: Implications for therapeutics

Albin, J. S. & Harris, R., Feb 1 2010, In : Expert reviews in molecular medicine. 12, e4.

Research output: Contribution to journalReview article

Virion
HIV-1
Proteins
Cytidine Deaminase
Virus Diseases
2009
18 Citations (Scopus)

Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS

Hultquist, J. F. & Harris, R., Dec 1 2009, In : Future Virology. 4, 6, p. 605-619 15 p.

Research output: Contribution to journalReview article

Mutation Rate
HIV-1
Acquired Immunodeficiency Syndrome
HIV
vif Gene Products
2006
26 Citations (Scopus)

Evaluation of molecular models for the affinity maturation of antibodies: Roles of cytosine deamination by AID and DNA repair

Samaranayake, M., Bujnicki, J. M., Carpenter, M. A. & Bhagwat, A. S., Feb 1 2006, In : Chemical Reviews. 106, 2, p. 700-719 20 p.

Research output: Contribution to journalReview article

Cytosine
Repair
Antibodies
DNA
Mutagenesis
43 Citations (Scopus)

Human APOBEC3 proteins, retrovirus restriction and HIV drug resistance

Haché, G., Mansky, L. M. & Harris, R., Jul 1 2006, In : AIDS Reviews. 8, 3, p. 148-157 10 p.

Research output: Contribution to journalReview article

Retroviridae
Drug Resistance
HIV
Retroviridae Infections
Deamination
2004
428 Citations (Scopus)

Retroviral restriction by APOBEC proteins

Harris, R. & Liddament, M. T., Nov 1 2004, In : Nature Reviews Immunology. 4, 11, p. 868-877 10 p.

Research output: Contribution to journalReview article

Vertebrates
Retroviridae Proteins
Immunoglobulin Genes
Proteins
Cytosine
1998
20 Citations (Scopus)

DNA transfer from Agrobacterium to plant cells in crown gall tumor disease.

Das, A., Jan 1 1998, In : Sub-Cellular Biochemistry. 29, p. 343-363 21 p.

Research output: Contribution to journalReview article

Bacterial DNA
Tumors
DNA
Plant Cells