Molecular and Cellular Therapeutics

Organization profile

Organization profile

A unit of the Academic Health Center, Molecular and Cellular Therapeutics offers state-of-the-art GMP/GTP compliant, full-service development and manufacturing of cell- and tissue-based products, monoclonal antibodies and other therapeutic proteins, as well as active pharmaceutical ingredients, for use in Phase I, II or III clinical trials.  Our fully-staffed technical and quality personnel with over 70 years of combined cell-based products experience, through product development and technical expertise, as well as medical and regulatory support, work to compress development timelines and translate research into medicine.

Fingerprint Dive into the research topics where Molecular and Cellular Therapeutics is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Fetal Blood Medicine & Life Sciences
Cord Blood Stem Cell Transplantation Medicine & Life Sciences
Cell- and Tissue-Based Therapy Medicine & Life Sciences
Graft vs Host Disease Medicine & Life Sciences
Blood Preservation Medicine & Life Sciences
Cryopreservation Medicine & Life Sciences
Regulatory T-Lymphocytes Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences

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Profiles

No photo of Diane M Kadidlo

Diane M Kadidlo

Person: Research Support

19992018

Research Output 1999 2017

17 Citations (Scopus)

Optimization of cGMP purification and expansion of umbilical cord blood–derived T-regulatory cells in support of first-in-human clinical trials

McKenna, D. H., Sumstad, D., Kadidlo, D. M., Batdorf, B., Lord, C. J., Merkel, S. C., Koellner, C. M., Curtsinger, J. M., June, C. H., Riley, J. L., Levine, B. L., Miller, J. S., Brunstein, C. G., Wagner, J. E., Blazar, B. R. & Hippen, K. L., Feb 1 2017, In : Cytotherapy. 19, 2, p. 250-262 13 p.

Research output: Contribution to journalArticle

Umbilical Cord
Regulatory T-Lymphocytes
Fetal Blood
Clinical Trials
Graft vs Host Disease
23 Citations (Scopus)

Clinical mesenchymal stromal cell products undergo functional changes in response to freezing

Pollock, K., Sumstad, D., Kadidlo, D., McKenna, D. H. & Hubel, A., Jan 1 2015, In : Cytotherapy. 17, 1, p. 38-45 8 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Freezing
Phenotype
Cell Aging
Cryopreservation
30 Citations (Scopus)

Autologous stem cell transplant recipients tolerate haploidentical related-donor natural killer cell-enriched infusions

Klingemann, H., Grodman, C., Cutler, E., Duque, M., Kadidlo, D. M., Klein, A. K., Sprague, K. A., Miller, K. B., Comenzo, R. L., Kewalramani, T., Yu, N., Van Etten, R. A. & McKenna, D. H., Feb 1 2013, In : Transfusion. 53, 2, p. 412-418 7 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Natural Killer Cells
Stem Cells
Tissue Donors
Transplants