Projects per year
Organization profile
Organization profile
A unit of the Academic Health Center, Molecular and Cellular Therapeutics offers state-of-the-art GMP/GTP compliant, full-service development and manufacturing of cell- and tissue-based products, monoclonal antibodies and other therapeutic proteins, as well as active pharmaceutical ingredients, for use in Phase I, II or III clinical trials. Our fully-staffed technical and quality personnel with over 70 years of combined cell-based products experience, through product development and technical expertise, as well as medical and regulatory support, work to compress development timelines and translate research into medicine.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Profiles
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PACT - Preclinical development of PB-drevived iTregs
National Heart, Lung, and Blood Institute
11/1/19 → 3/31/22
Project: Research project
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First-in-human phase 1 trial of induced regulatory T cells for graft-versus-host disease prophylaxis in HLA-matched siblings
MacMillan, M. L., Hippen, K. L., McKenna, D. H., Kadidlo, D. M., Sumstad, D., Defor, T. E., Brunstein, C. G., Holtan, S. G., Miller, J. S., Warlick, E. D., Weisdorf, D. J., Wagner, J. E. & Blazar, B. R., Mar 9 2021, In: Blood Advances. 5, 5, p. 1425-1436 12 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Optimization of cGMP purification and expansion of umbilical cord blood–derived T-regulatory cells in support of first-in-human clinical trials
McKenna, D. H., Sumstad, D., Kadidlo, D. M., Batdorf, B., Lord, C. J., Merkel, S. C., Koellner, C. M., Curtsinger, J. M., June, C. H., Riley, J. L., Levine, B. L., Miller, J. S., Brunstein, C. G., Wagner, J. E., Blazar, B. R. & Hippen, K. L., Feb 1 2017, In: Cytotherapy. 19, 2, p. 250-262 13 p.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations -
Clinical mesenchymal stromal cell products undergo functional changes in response to freezing
Pollock, K., Sumstad, D., Kadidlo, D., McKenna, D. H. & Hubel, A., Jan 1 2015, In: Cytotherapy. 17, 1, p. 38-45 8 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations