Organization profile

Organization profile

Microorganisms – bacteria, viruses, fungi – reside in diverse and heavily populated communities on the skin and mucous membranes of animals, including humans. Wherever they are located on or in the body, these microbes maintain intimate and often mutually beneficial relationships between themselves and their animal hosts. The vast community of bacteria residing in the digestive tract can undergo significant changes over the lifespan of food animals and people, and these shifts in population can affect the host’s overall health and development. Drugs, particularly antimicrobial agents, can contribute to these bacterial community shifts. Antimicrobial drugs can promote the growth of food animals, but their widespread use is contributing to increased microbial drug resistance.  Similarly, excessive antibiotic use by people can fight disease, but can also lead to the emergence of drug-resistant microorganisms.   Through genomic analyses and mathematical modeling, faculty in the Microbiome/Antibiotic Resistance research cluster are characterizing the intestinal bacteria, viruses and the small DNA molecules that transfer antibiotic resistance among bacteria in food animals.  They seek to discover how changes in the gut microbial community affect animal growth and well-being.  Their research will contribute to the development of antibiotic alternatives, such as new probiotics, to enhance animal growth and reduce the incidence of antimicrobial drug resistance.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Lawsonia Bacteria Medicine & Life Sciences
Lawsonia intracellularis Agriculture & Biology
Swine Medicine & Life Sciences
Escherichia coli Medicine & Life Sciences
digestive system diseases Agriculture & Biology
swine Agriculture & Biology
Plasmids Medicine & Life Sciences
Virulence Medicine & Life Sciences

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Projects 2004 2021

Research Output 1972 2018

2 Citations
Lawsonia Bacteria
Salmonella enterica
Vaccination
Swine
Clostridium butyricum
12 Citations

Characterization of the cutaneous mycobiota in healthy and allergic cats using next generation sequencing

Meason-Smith, C., Diesel, A., Patterson, A. P., Older, C. E., Johnson, T. J., Mansell, J. M., Suchodolski, J. S. & Rodrigues Hoffmann, A., Feb 1 2017, In : Veterinary Dermatology. 28, 1, p. 71-e17

Research output: Contribution to journalArticle

Cats
skin (animal)
cats
Skin
Dysbiosis
2 Citations

Inactivation of transcriptional regulators during withinhousehold evolution of Escherichia coli

Kisiela, D. I., Radey, M., Paul, S., Porter, S., Polukhina, K., Tchesnokova, V., Shevchenko, S., Chan, D., Aziz, M., Johnson, T. J., Price, L. B., Johnson, J. R. & Sokurenko, E. V., Jul 1 2017, In : Journal of bacteriology. 199, 13, e00036-17.

Research output: Contribution to journalArticle

Escherichia coli
Mutation
Cystitis
Pyelonephritis
Urine