Research Output

2020

Antigen discovery unveils resident memory and migratory cell roles in antifungal resistance

Dobson, H. E., Dias, L. D. S., Kohn, E. M., Fites, S., Wiesner, D. L., Dileepan, T., Kujoth, G. C., Abraham, A., Ostroff, G. R., Klein, B. S. & Wüthrich, M., May 1 2020, In : Mucosal Immunology. 13, 3, p. 518-529 12 p.

Research output: Contribution to journalArticle

Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota

Valentini, T. D., Lucas, S. K., Binder, K. A., Cameron, L. C., Motl, J. A., Dunitz, J. M. & Hunter, R. C., Dec 1 2020, In : Nature communications. 11, 1, 2287.

Research output: Contribution to journalArticle

Open Access

Developmental plasticity allows outside-in immune responses by resident memory T cells

Fonseca, R., Beura, L. K., Quarnstrom, C. F., Ghoneim, H. E., Fan, Y., Zebley, C. C., Scott, M. C., Fares-Frederickson, N. J., Wijeyesinghe, S., Thompson, E. A., Borges da Silva, H., Vezys, V., Youngblood, B. & Masopust, D., Apr 1 2020, In : Nature immunology. 21, 4, p. 412-421 10 p.

Research output: Contribution to journalArticle

Development and Validation of a Bordetella pertussis Whole-Genome Screening Strategy

Da Silva Antunes, R., Quiambao, L. G., Sutherland, A., Soldevila, F., Dhanda, S. K., Armstrong, S. K., Brickman, T. J., Merkel, T., Peters, B. & Sette, A., Jan 1 2020, In : Journal of Immunology Research. 2020, 8202067.

Research output: Contribution to journalArticle

Open Access

Disruption of Cross-Feeding Inhibits Pathogen Growth in the Sputa of Patients with Cystic Fibrosis

Flynn, J. M., Cameron, L. C., Wiggen, T. D., Dunitz, J. M., Harcombe, W. R. & Hunter, R. C., Apr 29 2020, In : mSphere. 5, 2

Research output: Contribution to journalArticle

Open Access

Erratum: The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts (Nucleic acids research (2018) 46 5 (2537-2547))

Guo, L., Sharma, S. D., Debes, J. D., Beisang, D., Rattenbacher, B., Louis, I. V. S., Wiesner, D. L., Cameron, C. E. & Bohjanen, P. R., Feb 20 2020, In : Nucleic acids research. 48, 3, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing — Implication for metabolic remodeling

Tateishi, Y., Minato, Y., Baughn, A. D., Ohnishi, H., Nishiyama, A., Ozeki, Y. & Matsumoto, S., Dec 1 2020, In : Scientific reports. 10, 1, 5449.

Research output: Contribution to journalArticle

Open Access

Glucocorticoid receptors are required effectors of TGFβ1-induced p38 MAPK signaling to advanced cancer phenotypes in triple-negative breast cancer

Perez Kerkvliet, C., Dwyer, A. R., Diep, C. H., Oakley, R. H., Liddle, C., Cidlowski, J. A. & Lange, C. A., May 1 2020, In : Breast Cancer Research. 22, 1, 39.

Research output: Contribution to journalArticle

Open Access

Gut dysbiosis during antileukemia chemotherapy versus allogeneic hematopoietic cell transplantation

Rashidi, A., Kaiser, T., Graiziger, C., Holtan, S. G., Rehman, T. U., Weisdorf, D. J., Dunny, G. M., Khoruts, A. & Staley, C., Apr 1 2020, In : Cancer. 126, 7, p. 1434-1447 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Impact of Na-translocating NADH: Quinone oxidoreductase on iron uptake and nqrM expression in Vibrio cholerae

Agarwal, S., Bernt, M., Toulouse, C., Kurz, H., Pfannstiel, J., D’Alvise, P., Hasselmann, M., Block, A. M., Häse, C. C., Fritz, G. & Steuber, J., Feb 1 2020, In : Journal of bacteriology. 202, 3, e00681-19.

Research output: Contribution to journalArticle

Integrating resident memory into T cell differentiation models

Rosato, P. C., Wijeyesinghe, S., Stolley, J. M. & Masopust, D., Apr 2020, In : Current Opinion in Immunology. 63, p. 35-42 8 p.

Research output: Contribution to journalReview article

Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function

Sarhan, D., Wang, J., Arvindam, U. S., Hallstrom, C., Verneris, M. R., Grzywacz, B., Warlick, E., Blazar, B. R. & Miller, J. S., Mar 12 2020, In : JCI Insight. 5, 5, e130155.

Research output: Contribution to journalArticle

Open Access

Neutrophils recirculate through lymph nodes to survey tissues for pathogens

Bogoslowski, A., Wijeyesinghe, S., Lee, W. Y., Chen, C. S., Alanani, S., Jenne, C., Steeber, D. A., Scheiermann, C., Butcher, E. C., Masopust, D. & Kubes, P., May 1 2020, In : Journal of Immunology. 204, 9, p. 2552-2561 10 p.

Research output: Contribution to journalArticle

Parallel genomics uncover novel enterococcal-bacteriophage interactions

Chatterjee, A., Willett, J. L. E., Nguyen, U. T., Monogue, B., Palmer, K. L., Dunny, G. M. & Duerkop, B. A., Mar 1 2020, In : mBio. 11, 2, e03120-19.

Research output: Contribution to journalArticle

Open Access

PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection

Im, S. J., Konieczny, B. T., Hudson, W. H., Masopust, D. & Ahmed, R., Feb 25 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 8, p. 4292-4299 8 p.

Research output: Contribution to journalArticle

PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma

Smeester, B. A., Slipek, N. J., Pomeroy, E. J., Laoharawee, K., Osum, S. H., Larsson, A. T., Williams, K. B., Stratton, N., Yamamoto, K., Peterson, J. J., Rathe, S. K., Mills, L. J., Hudson, W. A., Crosby, M. R., Wang, M., Rahrmann, E. P., Moriarity, B. S. & Largaespada, D. A., Jul 2020, In : Bone. 136, 115353.

Research output: Contribution to journalArticle

Review: Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)

Pastick, K. A., Okafor, E. C., Wang, F., Lofgren, S. M., Skipper, C. P., Nicol, M. R., Pullen, M. F., Rajasingham, R., McDonald, E. G., Lee, T. C., Schwartz, I. S., Kelly, L. E., Lother, S. A., Mitjà, O., Letang, E., Abassi, M. & Boulware, D. R., Mar 16 2020, In : Open Forum Infectious Diseases. 7, 4, ofaa130.

Research output: Contribution to journalReview article

Open Access

Risk factors for neo-osteogenesis in cystic fibrosis and non‒cystic fibrosis chronic rhinosinusitis

Karempelis, P., Karp, E., Rubin, N., Hunter, R., Dunitz, J. & Boyer, H., Apr 1 2020, In : International Forum of Allergy and Rhinology. 10, 4, p. 505-510 6 p.

Research output: Contribution to journalArticle

Single-cell analysis reveals that the enterococcal sex pheromone response results in expression of full-length conjugation operon transcripts in all induced cells

Erickson, R. J. B., Bandyopadhyay, A. A., Barnes, A. M. T., O'Brien, S. A., Hu, W. S. & Dunny, G. M., Mar 1 2020, In : Journal of bacteriology. 202, 8, e00685-19.

Research output: Contribution to journalArticle

The Bewildering Antitubercular Action of Pyrazinamide

Lamont, E. A., Dillon, N. A. & Baughn, A. D., May 20 2020, In : Microbiology and molecular biology reviews : MMBR. 84, 2

Research output: Contribution to journalReview article

The impact of Lactococcus lactis (probiotic nasal rinse) co-culture on growth of patient-derived strains of Pseudomonas aeruginosa

Cho, D. Y., Skinner, D., Lim, D. J., Mclemore, J. G., Koch, C. G., Zhang, S., Swords, W. E., Hunter, R., Crossman, D. K., Crowley, M. R., Grayson, J. W., Rowe, S. M. & Woodworth, B. A., Apr 1 2020, In : International Forum of Allergy and Rhinology. 10, 4, p. 444-449 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Microbiome and Chronic Rhinosinusitis

Cho, D. Y., Hunter, R. C. & Ramakrishnan, V. R., May 2020, In : Immunology and Allergy Clinics of North America. 40, 2, p. 251-263 13 p.

Research output: Contribution to journalReview article

Open Access
2019

A conserved mechanism of APOBEC3 relocalization by herpesviral ribonucleotide reductase large subunits

Cheng, A. Z., Moraes, S. N., Attarian, C., Yockteng-Melgar, J., Jarvis, M. C., Biolatti, M., Galitska, G., Dell'Oste, V., Frappier, L., Bierle, C. J., Rice, S. A. & Harris, R. S., Dec 1 2019, In : Journal of virology. 9, 23, e01539-19.

Research output: Contribution to journalArticle

1 Scopus citations

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

ASTRO-CM Team, Aug 2019, In : The Lancet Infectious Diseases. 19, 8, p. 843-851 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation

McCurtain, J. L., Gilbertsen, A. J., Evert, C., Williams, B. J. & Hunter, R. C., Mar 2019, In : Journal of medical microbiology. 68, 3, p. 446-455 10 p.

Research output: Contribution to journalArticle

Open Access

A new flavor of entry exclusion in ICE elements provides a selective advantage for the element and its host

Dunny, G. M. & Hirt, H., Oct 1 2019, In : Molecular Microbiology. 112, 4, p. 1061-1065 5 p.

Research output: Contribution to journalComment/debate

Open Access

A putative enoyl-CoA hydratase contributes to biofilm formation and the antibiotic tolerance of Achromobacter xylosoxidans

Cameron, L. C., Bonis, B., Phan, C. Q., Kent, L. A., Lee, A. K. & Hunter, R. C., Dec 1 2019, In : NPJ biofilms and microbiomes. 5, 1, 20.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation

Vacchio, M. S., Ciucci, T., Gao, Y., Watanabe, M., Balmaceno-Criss, M., McGinty, M. T., Huang, A., Xiao, Q., McConkey, C., Zhao, Y., Shetty, J., Tran, B., Pepper, M., Vahedi, G., Jenkins, M. K., McGavern, D. B. & Bosselut, R., Sep 17 2019, In : Immunity. 51, 3, p. 465-478.e6

Research output: Contribution to journalArticle

1 Scopus citations

A titanic drug resistance threat in Cryptococcus neoformans

Zafar, H., Altamirano, S., Ballou, E. R. & Nielsen, K., Dec 2019, In : Current Opinion in Microbiology. 52, p. 158-164 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses

Beura, L. K., Fares-Frederickson, N. J., Steinert, E. M., Scott, M. C., Thompson, E. A., Fraser, K. A., Schenkel, J. M., Vezys, V. & Masopust, D., May 1 2019, In : Journal of Experimental Medicine. 216, 5, p. 1214-1229 16 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Chronic stimulation drives human NK cell dysfunction and epigenetic reprograming

Merino, A., Zhang, B., Dougherty, P., Luo, X., Wang, J., Blazar, B. R., Miller, J. S. & Cichocki, F., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3770-3785 16 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Chrysalis: A new method for high-throughput histo-cytometry analysis of images and movies

Kotov, D. I., Pengo, T., Mitchell, J. S., Gastinger, M. J. & Jenkins, M. K., Jan 1 2019, In : Journal of Immunology. 202, 1, p. 300-308 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma

Burrack, A. L., Spartz, E. J., Raynor, J. F., Wang, I., Olson, M. & Stromnes, I. M., Aug 20 2019, In : Cell reports. 28, 8, p. 2140-2155.e6

Research output: Contribution to journalArticle

Open Access

Comprehensive analysis of resistance-nodulation-cell division superfamily (RND) efflux pumps from Serratia marcescens, Db10

Toba, S., Minato, Y., Kondo, Y., Hoshikawa, K., Minagawa, S., Komaki, S., Kumagai, T., Matoba, Y., Morita, D., Ogawa, W., Gotoh, N., Tsuchiya, T. & Kuroda, T., Mar 19 2019, In : Scientific reports. 9, 1, 4854.

Research output: Contribution to journalArticle

Open Access

Cutting edge: T cell–dependent plasmablasts form in the absence of single differentiated CD4 + T cell subsets

Kotov, J. A. & Jenkins, M., Jan 15 2019, In : Journal of Immunology. 202, 2, p. 401-405 5 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Dendritic cell NLRC4 regulates influenza A virus-specific CD4+ T cell responses through FasL expression

Hornick, E. E., Dagvadorj, J., Zacharias, Z. R., Miller, A. M., Langlois, R. A., Chen, P., Legge, K. L., Bishop, G. A., Sutterwala, F. S. & Cassel, S. L., Jan 1 2019, In : Journal of Clinical Investigation. 129, 7, p. 2888-2897 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Differential effects of depleting versus programming tumor-associated macrophages on engineered T cells in pancreatic ductal adenocarcinoma

Stromnes, I. M., Burrack, A. L., Hulbert, A., Bonson, P., Black, C., Brockenbrough, J. S., Raynor, J. F., Spartz, E. J., Pierce, R. H., Greenberg, P. D. & Hingorani, S. R., Jun 2019, In : Cancer Immunology Research. 7, 6, p. 977-989 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Dysbiosis patterns during re-induction/salvage versus induction chemotherapy for acute leukemia

Rashidi, A., Kaiser, T., Shields-Cutler, R. R., Graiziger, C., Holtan, S. G., Rehman, T. U., Wasko, J., Weisdorf, D. J., Dunny, G. M., Khoruts, A. & Staley, C. M., Dec 1 2019, In : Scientific reports. 9, 1, 6083.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Early E. Casseliflavus gut colonization and outcomes of allogeneic hematopoietic cell transplantation

Rashidi, A., Ebadi, M., Shields-Cutler, R. R., Kruziki, K., Manias, D. A., Barnes, A. M. T., DeFor, T. E., Ferrieri, P., Young, J. A. H., Knights, D., Blazar, B. R., Weisdorf, D. J. & Dunny, G. M., Jan 1 2019, In : PloS one. 14, 8, e0220850.

Research output: Contribution to journalArticle

Open Access

Effects of endogenous levels of master regulator PrgX and peptide pheromones on inducibility of conjugation in the enterococcal pCF10 system

Erickson, R. J. B., Manias, D. A., Hu, W. S. & Dunny, G. M., Sep 1 2019, In : Molecular Microbiology. 112, 3, p. 1010-1023 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Engineered small-molecule control of influenza A virus replication

Fay, E. J., Aron, S. L., Stone, I. A., Waring, B. M., Plemper, R. K. & Langlois, R. A., Jan 1 2019, In : Journal of virology. 93, 1, e01677-18.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Enterococcus faecalis enhances expression and activity of the enterohemorrhagic escherichia coli type III secretion system

Cameron, E. A., Sperandio, V. & Dunny, G. M., Nov 1 2019, In : mBio. 10, 6, e02547-19.

Research output: Contribution to journalArticle

Open Access

Erratum: Correction for Keogh et al., "Extracellular Electron Transfer Powers Enterococcus faecalis Biofilm Metabolism" (mBio (2018) 9 2 PII: e01080-19)

Keogh, D., Lam, L. N., Doyle, L. E., Matysik, A., Pavagadhi, S., Umashankar, S., Low, P. M., Dale, J. L., Song, Y., Ng, S. P., Boothroyd, C. B., Dunny, G. M., Swarup, S., Williams, R. B. H., Marsili, E. & Kline, K. A., Jun 18 2019, In : mBio. 10, 3

Research output: Contribution to journalComment/debate

Open Access
Open Access

Generation of 13C-Labeled MUC5AC Mucin Oligosaccharides for Stable Isotope Probing of Host-Associated Microbial Communities

Evert, C., Loesekann, T., Bhat, G., Shajahan, A., Sonon, R., Azadi, P. & Hunter, R. C., Mar 8 2019, In : ACS Infectious Diseases. 5, 3, p. 385-393 9 p.

Research output: Contribution to journalArticle

Genomewide assessment of mycobacterium tuberculosis conditionally essential metabolic pathways

Minato, Y., Gohl, D. M., Thiede, J. M., Chacón, J. M., Harcombe, W. R., Maruyama, F., Baughn, A. D. & Dorrestein, P. C., Jun 25 2019, In : mSystems. 4, 4, e00070-19.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access

HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators

Salamango, D. J., Ikeda, T., Moghadasi, S. A., Wang, J., McCann, J. L., Serebrenik, A. A., Ebrahimi, D., Jarvis, M. C., Brown, W. L. & Harris, R. S., Oct 29 2019, In : Cell reports. 29, 5, p. 1057-1065.e4

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

HIV-Associated cryptococcal meningitis occurring at relatively higher CD4 counts

Tugume, L., Rhein, J., Hullsiek, K. H., Mpoza, E., Kiggundu, R., Ssebambulidde, K., Schutz, C., Taseera, K., Williams, D. A., Abassi, M., Muzoora, C., Musubire, A. K., Meintjes, G., Meya, D. B., Boulware, D. R., Nabeta, H. W., Ndyetukira, J. F., Ahimbisibwe, C., Kugonza, F., Namuju, C. & 28 others, Sadiq, A., Namudde, A., Mwesigye, J., Kandole, T. K., Kwizera, R., Kirumira, P., Okirwoth, M., Akampurira, A., Luggya, T., Kaboggoza, J., Laker, E., Atwine, L., Muganzi, D., Evans, E. E., Bridge, S. C., Velamakanni, S. S., Rajasingham, R., Pastick, K., Stadelman, A., Flynn, A., Fujita, A. W., Mukaremera, L., Lofgren, S. M., Morawski, B. M., Bangdiwala, A., Nielsen, K., Bohjanen, P. R. & Kambugu, A., Feb 23 2019, In : Journal of Infectious Diseases. 219, 6, p. 877-883 7 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations