Research Output 1973 2019

1994
21 Citations (Scopus)

Utilization of the resolved l-isomer of 2-amino-6-phosphonohexanoic acid (l-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons

Schulte, M. K., Roon, R. J., Chalmers, D. J., Sunter, D. C. & Koerner, J. F., Jun 27 1994, In : Brain Research. 649, 1-2, p. 203-207 5 p.

Research output: Contribution to journalArticle

Quisqualic Acid
Pyramidal Cells
N-Methylaspartate
Organophosphonates
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
1993
19 Citations (Scopus)

Quisqualic acid induced sensitization and the active uptake of l-quisqualic acid by hippocampal slices

Schulte, M. K., Roon, R. J. & Koerner, J. F., Mar 5 1993, In : Brain Research. 605, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Quisqualic Acid
Pyramidal Cells
o-Phthalaldehyde
1992
27 Citations (Scopus)

Quisqualic Acid Analogues: Synthesis of β-Heterocyclic 2-Aminopropanoic Acid Derivatives and Their Activity at a Novel Quisqualate-Sensitized Site

Subasinghe, N., Schulte, M., Roon, R. J., Koerner, J. F. & Johnson, R. L., Nov 1 1992, In : Journal of Medicinal Chemistry. 35, 24, p. 4602-4607 6 p.

Research output: Contribution to journalArticle

Quisqualic Acid
Acids
Inhibitory Concentration 50
Pyramidal Cells
Succinimides
1991
298 Citations (Scopus)

Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle

Ohlendieck, K., Ervasti, J. M., Matsumura, K., Kahl, S. D., Leveille, C. J. & Campbell, K. P., Jan 1 1991, In : Neuron. 7, 3, p. 499-508 10 p.

Research output: Contribution to journalArticle

Utrophin
Neuromuscular Junction
Skeletal Muscle
Dystrophin
Inbred mdx Mouse
13 Citations (Scopus)

Ryanodine receptor in different malignant hyperthermia-susceptible porcine muscles

Ervasti, J. M., Strand, M. A., Hanson, T. P., Mickelson, J. R. & Louis, C. F., Feb 20 1991, In : American Journal of Physiology - Cell Physiology. 260, 1 29-1

Research output: Contribution to journalArticle

Malignant Hyperthermia
Ryanodine Receptor Calcium Release Channel
Sarcoplasmic Reticulum
Muscle
Ryanodine
1990
26 Citations (Scopus)

Expression of mammalian liver glycolytic/ gluconeogenic enzymes in Escherichia coli: Recovery of active enzyme is strain and temperature dependent

Lin, K., Kurland, I., Xu, L. Z., Lange, A. J., Pilkis, J., El-Maghrabi, M. R. & Pilkis, S. J., Jan 1 1990, In : Protein Expression and Purification. 1, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

Escherichia coli
Temperature
Liver
Enzymes
Fructose-Bisphosphatase
17 Citations (Scopus)

Sequence of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase

Lange, A. J. & Pilkis, S. J., Jun 25 1990, In : Nucleic acids research. 18, 12, 1 p.

Research output: Contribution to journalComment/debate

Nucleic Acid Sequence Homology
Molecular Sequence Data
Nucleic acid sequences
Phosphofructokinase-2
Multienzyme Complexes
38 Citations (Scopus)

Synthesis of Acyclic and Dehydroaspartic Acid Analogues of Ac-Asp-Glu-OH and Their Inhibition of Rat Brain N-Acetylated α-Linked Acidic Dipeptidase (NAALA Dipeptidase)

Subasinghe, N., Schulte, M., Chan, M. Y. M., Roon, R. J., Koerner, J. F. & Johnson, R. L., Jan 1 1990, In : Journal of Medicinal Chemistry. 33, 10, p. 2734-2744 11 p.

Research output: Contribution to journalArticle

aspartylglutamate
Acyclic Acids
aspartyl-aspartic acid
glutamyl-glutamic acid
Brain
1989
23 Citations (Scopus)

Altered transverse tubule dihydropyridine receptor binding in malignant hyperthermia

Ervasti, J. M., Claessens, M. T., Mickelson, J. R. & Louis, C. F., Jan 1 1989, In : Journal of Biological Chemistry. 264, 5, p. 2711-2717 7 p.

Research output: Contribution to journalArticle

Nitrendipine
Malignant Hyperthermia
L-Type Calcium Channels
Muscle
Proteins
6 Citations (Scopus)

An electron paramagnetic resonance study of skeletal muscle membrane fluidity in malignant hyperthermia

Ervasti, J. M., Mickelson, J. R., Lewis, S. M., Thomas, D. D. & Louis, C. F., Nov 17 1989, In : BBA - Biomembranes. 986, 1, p. 70-74 5 p.

Research output: Contribution to journalArticle

Malignant Hyperthermia
Membrane Fluidity
Fluidity
Electron Spin Resonance Spectroscopy
Paramagnetic resonance
6 Citations (Scopus)

High-Affinity Transport of L-Glutamine by a Plasma Membrane Preparation from Rat Brain

Roon, R. J., Shofner, S. A. & Koerner, J. F., Jan 1 1989, In : Biochemistry. 28, 20, p. 8083-8087 5 p.

Research output: Contribution to journalArticle

Cell membranes
Glutamine
Rats
Brain
Cell Membrane
12 Citations (Scopus)

Sequence of the 5′-flanking region of the rat 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase gene: Regulation by glucocorticoids

Lange, A. J., Kummel, L., El-Maghrabi, M. R., Tauler, A., Colosia, A., Marker, A. & Pilkis, S. J., Jul 31 1989, In : Biochemical and Biophysical Research Communications. 162, 2, p. 753-760 8 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
5' Flanking Region
Gene expression
Glucocorticoids
Muscle
11 Citations (Scopus)

Transverse tubule calcium regulation in malignant hyperthermia

Ervasti, J. M., Mickelson, J. R. & Louis, C. F., Jan 1 1989, In : Archives of Biochemistry and Biophysics. 269, 2, p. 497-506 10 p.

Research output: Contribution to journalArticle

Malignant Hyperthermia
Calcium
Muscle
Permeability
Skeletal Muscle
1988
34 Citations (Scopus)

Asparaginase II of Saccharomyces cerevisiae. Characterization of the ASP3 gene

Kim, K. W., Kamerud, J. Q., Livingston, D. M. & Roon, R. J., Jan 1 1988, In : Journal of Biological Chemistry. 263, 24, p. 11948-11953 6 p.

Research output: Contribution to journalArticle

Asparaginase
Yeast
Saccharomyces cerevisiae
Genes
Nitrogen
1986
4 Citations (Scopus)

Asparaginase II of Saccharomyces cerevisiae: Selection of four mutations that cause derepressed enzyme synthesis

Kamerud, J. Q. & Roon, R. J., Jan 1 1986, In : Journal of bacteriology. 165, 1, p. 293-296 4 p.

Research output: Contribution to journalArticle

Asparaginase
Saccharomyces cerevisiae
Mutation
Enzymes
Nitrogen
1984

A laboratory course in clinical biochemistry for first year medical students

Van Pilsum, J. F. & Roon, R. J., Jan 1 1984, In : Federation Proceedings. 43, 6

Research output: Contribution to journalArticle

Medical Students
Biochemistry
2 Citations (Scopus)

Asparaginase II of Saccharomyces cerevisiae: Positive selection of two mutations that prevent enzyme synthesis

Kim, K. W. & Roon, R. J., Jan 1 1984, In : Journal of Bacteriology. 157, 3, p. 958-961 4 p.

Research output: Contribution to journalArticle

Asparaginase
Saccharomyces cerevisiae
Mutation
Enzymes
D-Aspartic Acid

Secretion of asparaginase II by yeast spheroplasts

Kyu Won Kim, W. K., Kamerud, J. & Roon, R. J., Jan 1 1984, In : Federation Proceedings. 43, 6

Research output: Contribution to journalArticle

Spheroplasts
Asparaginase
Yeasts
1983
3 Citations (Scopus)

Asparaginase II of Saccharomyces cerevisiae: Comparison of Enzyme Stability in Vivo and in Vitro

Kim, K. W. & Roon, R. J., Jan 1 1983, In : Biochemistry. 22, 11, p. 2704-2707 4 p.

Research output: Contribution to journalArticle

Enzyme Stability
Asparaginase
Yeast
Saccharomyces cerevisiae
Enzymes

The experimental use of cooperative learning groups in a biochemistry laboratory course for first-year medical students

Roon, R. J., Van Pilsum, J. F., Harris, I., Rosenberg, P., Johnson, R., Liaw, C. & Rosenthal, L., Jan 1 1983, In : Biochemical Education. 11, 1, p. 12-15 4 p.

Research output: Contribution to journalArticle

Biochemistry
Students
1982
12 Citations (Scopus)

Derepression of asparaginase II during exponential growth of Saccharomyces cerevisiae on ammonium ion

Roon, R. J., Murdoch, M., Kunze, B. & Dunlop, P. C., Jan 1 1982, In : Archives of Biochemistry and Biophysics. 219, 1, p. 101-109 9 p.

Research output: Contribution to journalArticle

Asparaginase
Asparagine
Glutamine
Ammonium Compounds
Yeast
8 Citations (Scopus)

Nitrogen catabolite repression in a glutamate auxotroph of Saccharomyces cerevisiae

Kang, L., Keeler, M. L., Dunlop, P. C. & Roon, R. J., Jan 1 1982, In : Journal of Bacteriology. 151, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Enzyme Repression
Glutamates
Catabolite Repression
Ketoglutaric Acids
Asparaginase

Transport and metabolic effect of α-aminoisobutyric acid in Saccharomyces cerevisiae

Kim, K. W. & Roon, R. J., Jan 1 1982, In : Federation Proceedings. 41, 4

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
2-aminoisobutyric acid
8 Citations (Scopus)

Transport and metabolic effects of α-aminoisobutyric acid in saccharomyces cerevisiae

Kim, K. W. & Roon, R. J., Nov 24 1982, In : BBA - General Subjects. 719, 2, p. 356-362 7 p.

Research output: Contribution to journalArticle

Aminoisobutyric Acids
Yeast
Saccharomyces cerevisiae
Nitrogen
Asparaginase
1980
122 Citations (Scopus)

Neutropenia and impaired neutrophil migration in type IB glycogen storage disease

Beaudet, A. L., Anderson, D. C., Michels, V. V., Arion, W. J. & Lange, A. J., Jan 1 1980, In : The Journal of pediatrics. 97, 6, p. 906-910 5 p.

Research output: Contribution to journalArticle

Neutropenia
Neutrophils
Glucose-6-Phosphate
Cell Movement
Bone Marrow
19 Citations (Scopus)

Nitrogen catabolite repression of asparaginase II in Saccharomyces cerevisiae

Dunlop, P. C., Meyer, G. M. & Roon, R. J., Jan 1 1980, In : Journal of bacteriology. 143, 1, p. 422-426 5 p.

Research output: Contribution to journalArticle

Enzyme Repression
Catabolite Repression
Asparaginase
Ammonium Sulfate
Saccharomyces cerevisiae
17 Citations (Scopus)

Reactions of asparaginase II of Saccharomyces cerevisiae. A mechanistic analysis of hydrolysis and hydroxylaminolysis

Dunlop, P. C., Meyer, G. M. & Roon, R. J., Jan 1 1980, In : Journal of Biological Chemistry. 255, 4, p. 1542-1546 5 p.

Research output: Contribution to journalArticle

Hydroxylamines
pH
Asparaginase
Substrate Specificity
Yeast
5 Citations (Scopus)

Transport and metabolism of N-δ-chloroacetyl-l-ornithine by Saccharomyces cerevisiae

Larimore, F. S., Kuisk, I., Korkowski, P. M. & Roon, R. J., Jan 1 1980, In : Archives of Biochemistry and Biophysics. 204, 1, p. 234-240 7 p.

Research output: Contribution to journalArticle

Ornithine
Metabolism
Yeast
Saccharomyces cerevisiae
Amino Acid Transport Systems
1979

Transport and metabolism of N-δ-chloroacetyl-L-ornithine by Saccharomyces cerevisiae

Larimore, F. S. & Roon, R. J., Jan 1 1979, In : Federation Proceedings. 38, 3 I

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
N-delta-chloroacetyl-L-ornithine
1978
13 Citations (Scopus)

Characterization of a Dio-9-resistant strain of Saccharomyces cerevisiae

Roon, R. J., Larimore, F. S., Meyer, G. M. & Kreisle, R. A., Jan 15 1978, In : Archives of Biochemistry and Biophysics. 185, 1, p. 142-150 9 p.

Research output: Contribution to journalArticle

Yeast
Saccharomyces cerevisiae
Adenosine Triphosphatases
Protons
Yeasts
48 Citations (Scopus)

Characterization of two forms of asparaginase in Saccharomyces cerevisiae

Dunlop, P. C., Meyer, G. M., Ban, D. & Roon, R. J., Jan 1 1978, In : Journal of Biological Chemistry. 253, 4, p. 1297-1304 8 p.

Research output: Contribution to journalArticle

Asparaginase
Substrate Specificity
Thermodynamics
Yeast
Isoenzymes
8 Citations (Scopus)

Possible Site-Specific Reagent for the General Amino Acid Transport System of Saccharomyces cerevisiae

Larimore, F. S. & Roon, R. J., Jan 1 1978, In : Biochemistry. 17, 3, p. 431-436 6 p.

Research output: Contribution to journalArticle

Amino Acid Transport Systems
Ornithine
Yeast
Saccharomyces cerevisiae
Tryptophan
1977
14 Citations (Scopus)

Evidence for a common component in kinetically distinct transport systems of Saccharomyces cerevisiae

Roon, R. J., Meyer, G. M. & Larimore, F. S., Jan 1 1977, In : MGG Molecular & General Genetics. 158, 2, p. 185-191 7 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Amino Acid Transport Systems
Ionophores
Ammonia
Adenosine Triphosphatases
41 Citations (Scopus)

Negative interactions between amino acid and methylamine/ammonia transport systems of Saccharomyces cerevisiae

Roon, R. J., Levy, J. S. & Larimore, F., Dec 1 1977, In : Journal of Biological Chemistry. 252, 11, p. 3599-3604 6 p.

Research output: Contribution to journalArticle

Ammonia
Yeast
Saccharomyces cerevisiae
Amino Acids
Active Biological Transport
1976
69 Citations (Scopus)
Glucosephosphates
pH
Drug Stability
Glucose-6-Phosphatase
Glucose-6-Phosphate
7 Citations (Scopus)

The intracellular location of hepatic fructose 1,6-biphosphate aldolase

Arion, W. J. & Lange, A. J., Feb 9 1976, In : Biochemical and Biophysical Research Communications. 68, 3, p. 770-775 6 p.

Research output: Contribution to journalArticle

Fructose-Bisphosphate Aldolase
Fructose
Endoplasmic Reticulum
Liver
Dilution
9 Citations (Scopus)

Utilization of D asparagine by Saccharomyces cerevisiae

Dunlop, P. C., Roon, R. J. & Even, H. L., Dec 1 1976, In : Journal of Bacteriology. 125, 3, p. 999-1004 6 p.

Research output: Contribution to journalArticle

Asparagine
Asparaginase
Saccharomyces cerevisiae
Nitrogen
varespladib methyl
1975
36 Citations (Scopus)

Inhibition of amino acid transport by ammonium ion in Saccharomyces cerevisiae

Roon, R. J., Larimore, F. & Levy, J. S., Dec 1 1975, In : Journal of Bacteriology. 124, 1, p. 325-331 7 p.

Research output: Contribution to journalArticle

Ion Transport
Ammonium Sulfate
Ammonium Compounds
Saccharomyces cerevisiae
Cycloheximide
34 Citations (Scopus)

L Asparaginase of Saccharomyces cerevisiae: an extracellular enzyme

Dunlop, P. C. & Roon, R. J., Dec 1 1975, In : Journal of bacteriology. 122, 3, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

Hydroxymercuribenzoates
Species Specificity
Asparaginase
Stereoisomerism
Cell-Free System
80 Citations (Scopus)

Methylamine and ammonia transport in Saccharomyces cerevisiae

Roon, R. J., Even, H. L., Dunlop, P. & Larimore, F. L., Dec 1 1975, In : Journal of bacteriology. 122, 2, p. 502-503 2 p.

Research output: Contribution to journalArticle

Carbon Radioisotopes
Methylamines
Active Biological Transport
Cycloheximide
Ammonia
1974
54 Citations (Scopus)

Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide dependent enzyme from Saccharomyces cerevisiae

Roon, R. J., Even, H. L. & Larimore, F., Dec 1 1974, In : Journal of bacteriology. 118, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Glutamate Synthase
Glutamate Dehydrogenase
Glutamine
NAD
Glutamate Synthase (NADH)
1973
18 Citations (Scopus)
Methylamines
Glutamates
Asparaginase
Glutamate Dehydrogenase
Cell-Free System