Research Output 1973 2019

2011
132 Citations (Scopus)

Guanylyl cyclase structure, function and regulation

Potter, L. R., Dec 1 2011, In : Cellular Signalling. 23, 12, p. 1921-1926 6 p.

Research output: Contribution to journalReview article

Guanylate Cyclase
Cyclic GMP
Guanylate Cyclase-Activating Proteins
Nitric Oxide
Light Signal Transduction
34 Citations (Scopus)

Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva

Bandhakavi, S., Van Riper, S. K., Tawfik, P. N., Stone, M. D., Haddad, T., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., Mar 4 2011, In : Journal of Proteome Research. 10, 3, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

Pulse time modulation
Saliva
Libraries
Workflow
Proteins
42 Citations (Scopus)

Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response

Ralat, L. A., Guo, Q., Ren, M., Funke, T., Dickey, D. M., Potter, L. R. & Tang, W. J., Feb 11 2011, In : Journal of Biological Chemistry. 286, 6, p. 4670-4679 10 p.

Research output: Contribution to journalArticle

Insulysin
Natriuretic Peptides
Atrial Natriuretic Factor
Cyclic GMP
Cyclic Peptides
29 Citations (Scopus)

Internal deletion compromises the stability of dystrophin

Henderson, D. M., Belanto, J. J., Li, B., Heun-Johnson, H. & Ervasti, J. M., Aug 1 2011, In : Human Molecular Genetics. 20, 15, p. 2955-2963 9 p., ddr199.

Research output: Contribution to journalArticle

Dystrophin
Utrophin
Freezing
Proteins
Duchenne Muscular Dystrophy
32 Citations (Scopus)

Large-scale phosphoproteomics analysis of whole saliva reveals a distinct phosphorylation pattern

Stone, M. D., Chen, X., McGowan, T., Bandhakavi, S., Cheng, B., Rhodus, N. L. & Griffin, T. J., Apr 1 2011, In : Journal of Proteome Research. 10, 4, p. 1728-1736 9 p.

Research output: Contribution to journalArticle

Phosphorylation
Phosphoproteins
Saliva
Salivary Proteins and Peptides
Phosphotransferases
46 Citations (Scopus)

Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-γ activation and function in lipid homeostasis and energy expenditure

Jin, D., Guo, H., Bu, S. Y., Zhang, Y., Hannaford, J., Mashek, D. & Chen, X., Feb 1 2011, In : FASEB Journal. 25, 2, p. 754-764 11 p.

Research output: Contribution to journalArticle

Lipocalins
rosiglitazone
Peroxisome Proliferator-Activated Receptors
Energy Metabolism
Modulators
27 Citations (Scopus)

Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1

Stapleton, C. M., Mashek, D., Wang, S., Nagle, C. A., Cline, G. W., Thuillier, P., Leesnitzer, L. M., Li, L. O., Stimmel, J. B., Shulman, G. I. & Coleman, R. A., May 2 2011, In : PloS one. 6, 4, e18932.

Research output: Contribution to journalArticle

glycerol-3-phosphate acyltransferase
Acyltransferases
Peroxisome Proliferator-Activated Receptors
Chinese hamsters
Cricetulus
114 Citations (Scopus)

Mammalian triacylglycerol metabolism: Synthesis, lipolysis, and signaling

Coleman, R. A. & Mashek, D., Oct 12 2011, In : Chemical Reviews. 111, 10, p. 6359-6386 28 p.

Research output: Contribution to journalReview article

Metabolism
Protein Isoforms
Triglycerides
Fats
Nutrition
164 Citations (Scopus)

Natriuretic peptide metabolism, clearance and degradation

Potter, L. R., Jun 1 2011, In : FEBS Journal. 278, 11, p. 1808-1817 10 p.

Research output: Contribution to journalReview article

Natriuretic Peptides
Metabolism
Degradation
Guanylate Cyclase
Insulysin
26 Citations (Scopus)

ProBNP 1-108 is resistant to degradation and activates guanylyl cyclase-A with reduced potency

Dickey, D. M. & Potter, L. R., Sep 1 2011, In : Clinical chemistry. 57, 9, p. 1272-1278 7 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Degradation
Natriuretic Peptides
Peptide Receptors
atrial natriuretic factor receptor A
18 Citations (Scopus)

Quadriceps myopathy caused by skeletal muscle-specific ablation of βcyto-actin

Prins, K. W., Call, J. A., Lowe, D. A. & Ervasti, J. M., Mar 15 2011, In : Journal of cell science. 124, 6, p. 951-957 7 p.

Research output: Contribution to journalArticle

Muscular Diseases
Dystrophin
Actins
Skeletal Muscle
Spectrin
81 Citations (Scopus)

Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases

Potter, L. R., Jan 1 2011, In : Pharmacology and Therapeutics. 130, 1, p. 71-82 12 p.

Research output: Contribution to journalReview article

Peptide Receptors
Guanylate Cyclase
C-Type Natriuretic Peptide
Therapeutics
Dwarfism
30 Citations (Scopus)

Sample collection and handling considerations for peptidomic studies in whole saliva; implications for biomarker discovery

de Jong, E., Van Riper, S. K., Koopmeiners, J., Carlis, J. V. & Griffin, T. J., Nov 20 2011, In : Clinica Chimica Acta. 412, 23-24, p. 2284-2288 5 p.

Research output: Contribution to journalArticle

Biomarkers
Saliva
Freezing
Peptides
Nutritional Status
10 Citations (Scopus)

Structural and functional properties of the actin gene family

Bunnell, T. M. & Ervasti, J. M., Jan 1 2011, In : Critical Reviews in Eukaryotic Gene Expression. 21, 3, p. 255-266 12 p.

Research output: Contribution to journalArticle

Actins
Protein Isoforms
Genes
Amino Acid Sequence Homology
Animal Models
18 Citations (Scopus)

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice

Call, J. A., Ervasti, J. M. & Lowe, D. A., Jul 1 2011, In : Journal of Applied Physiology. 111, 1, p. 200-205 6 p.

Research output: Contribution to journalArticle

Utrophin
Inbred mdx Mouse
Dystrophin
Knockout Mice
Food
7 Citations (Scopus)

The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B

Robinson, J. W., Lou, X. & Potter, L. R., Sep 1 2011, In : British Journal of Pharmacology. 164, 2 B, p. 499-506 8 p.

Research output: Contribution to journalArticle

Guanylate Cyclase
C-Type Natriuretic Peptide
3T3-L1 Cells
atrial natriuretic factor receptor A
Natriuretic Peptides
320 Citations (Scopus)

The role of lipid droplets in metabolic disease in rodents and humans

Greenberg, A. S., Coleman, R. A., Kraemer, F. B., McManaman, J. L., Obin, M. S., Puri, V., Yan, Q. W., Miyoshi, H. & Mashek, D., Jun 1 2011, In : Journal of Clinical Investigation. 121, 6, p. 2102-2110 9 p.

Research output: Contribution to journalReview article

Metabolic Diseases
Rodentia
Lipids
Cholesterol Esters
Lipid Metabolism
4 Citations (Scopus)

Three-dimensional peptide fractionation for highly sensitive nanoscale LC-based shotgun proteomic analysis of complex protein mixtures

Bandhakavi, S., Markowski, T. W., Xie, H. & Griffin, T. J., Nov 10 2011, Nanoproteomics: Methods and Protocols. Toms, S. & Weil, R. (eds.). p. 47-56 10 p. (Methods in Molecular Biology; vol. 790).

Research output: Chapter in Book/Report/Conference proceedingChapter

Firearms
Complex Mixtures
Proteomics
High Pressure Liquid Chromatography
Peptides
16 Citations (Scopus)

Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice

Baltgalvis, K. A., Jaeger, M. A., Fitzsimons, D. P., Thayer, S. A., Lowe, D. A. & Ervasti, J. M., Oct 13 2011, In : Skeletal Muscle. 1, 1, 32.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Actins
Skeletal Muscle
Calcium
Muscles
115 Citations (Scopus)

β-Actin specifically controls cell growth, migration, and the G-actin pool

Bunnell, T. M., Burbach, B. J., Shimizu, Y. & Ervasti, J. M., Nov 1 2011, In : Molecular biology of the cell. 22, 21, p. 4047-4058 12 p.

Research output: Contribution to journalArticle

Cell Movement
Actins
Growth
Fibroblasts
Knockout Mice
2010
50 Citations (Scopus)
Microbiota
Tandem Mass Spectrometry
Metagenomics
Peptides
Archaea
5 Citations (Scopus)

Arg13 of B-type natriuretic peptide reciprocally modulates binding to guanylyl cyclase but not clearance receptors

Dickey, D. M., Barbieri, K. A., McGuirk, C. M. & Potter, L. R., Jan 1 2010, In : Molecular Pharmacology. 78, 3, p. 431-435 5 p.

Research output: Contribution to journalArticle

Guanylate Cyclase
Brain Natriuretic Peptide
Natriuretic Peptides
Heart Failure
Peptide Receptors
38 Citations (Scopus)

Cyclic AMP controls mTOR through regulation of the dynamic interaction between Rheb and phosphodiesterase 4D

Kim, H. W., Ha, S. H., Lee, M. N., Huston, E., Kim, D-H., Jang, S. K., Suh, P. G., Houslay, M. D. & Ryu, S. H., Nov 1 2010, In : Molecular and cellular biology. 30, 22, p. 5406-5420 15 p.

Research output: Contribution to journalArticle

Type 4 Cyclic Nucleotide Phosphodiesterase
Cyclic AMP
Second Messenger Systems
Transducers
mechanistic target of rapamycin complex 1
44 Citations (Scopus)

Delayed embryonic development and impaired cell growth and survival in Actg1 null mice

Bunnell, T. M. & Ervasti, J. M., Sep 1 2010, In : Cytoskeleton. 67, 9, p. 564-572 9 p.

Research output: Contribution to journalArticle

Embryonic Development
Actins
Cell Survival
Growth
Growth Disorders
42 Citations (Scopus)
Dystrophin
Missense Mutation
Thermodynamics
Actins
Duchenne Muscular Dystrophy
3 Citations (Scopus)

Guanylyl cyclases

Potter, L. R., Dec 1 2010, Handbook of Cell Signaling, 2/e. Elsevier Inc., Vol. 2. p. 1399-1407 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Guanylate Cyclase
Natriuretic Peptides
Amino Acids
Endothelium-Dependent Relaxing Factors
Peptide Receptors
59 Citations (Scopus)

Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways

Bu, S. Y. & Mashek, D., Nov 1 2010, In : Journal of Lipid Research. 51, 11, p. 3270-3280 11 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Fatty Acids
Liver
Fatty Acid Transport Proteins
RNA Interference
18 Citations (Scopus)

Human B-type natriuretic peptide is not degraded by meprin A

Dickey, D. M. & Potter, L. R., Oct 1 2010, In : Biochemical Pharmacology. 80, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

meprin A
Brain Natriuretic Peptide
Rats
Neprilysin
Membranes

Intracellular Fatty Acid Transport, Activation, and Trafficking

Mashek, D., Apr 16 2010, Adipose Tissue in Health and Disease. Wiley-VCH, p. 109-127 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fatty Acid-Binding Proteins
Acyl Coenzyme A
Metabolic Diseases
Metabolism
Fatty Acids
23 Citations (Scopus)

Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor γ activation in mice

Guo, X., Xu, K., Zhang, J., Li, H., Zhang, W., Wang, H., Lange, A. J., Chen, Y. E., Huo, Y. & Wu, C., Jul 30 2010, In : Journal of Biological Chemistry. 285, 31, p. 23711-23720 10 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Peroxisome Proliferator-Activated Receptors
Chemical activation
Adipocytes
Insulin
15 Citations (Scopus)

Iron-sparing response of mycobacterium avium subsp. paratuberculosis is strain dependent

Janagama, H. K., Senthilkumar, Bannantine, J. P., Kugadas, A., Jagtap, P., Higgins, L., Witthuhn, B. A. & Sreevatsan, S., Oct 26 2010, In : BMC microbiology. 10, 268.

Research output: Contribution to journalArticle

Paratuberculosis
Mycobacterium avium
Iron
Metabolic Networks and Pathways
Proteomics
1119 Citations (Scopus)

MTOR regulation of autophagy

Jung, C. H., Ro, S. H., Cao, J., Otto, N. M. & Kim, D-H., Jan 1 2010, In : FEBS Letters. 584, 7, p. 1287-1295 9 p.

Research output: Contribution to journalReview article

Autophagy
Sirolimus
Cell growth
Eukaryotic Cells
Growth

Oligonucleotide microarrays with high discriminating power for the detection of single nucleotide variations in the p53 gene

Hong, B. H., Oh, S. J., Ju, J., Hong, B. J., Jang, D. S., Yun, Y. S., Park, J. W. & Choi, K. Y., Dec 1 2010, In : Molecules and Cells. 30, 6, p. 575-579 5 p.

Research output: Contribution to journalArticle

p53 Genes
Oligonucleotide Array Sequence Analysis
Single Nucleotide Polymorphism
Nucleotides
Fluorescence
22 Citations (Scopus)

Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis

Aipoalani, D. L., O'Callaghan, B. L., Mashek, D., Mariash, C. N. & Towle, H. C., May 1 2010, In : Endocrinology. 151, 5, p. 2071-2077 7 p.

Research output: Contribution to journalArticle

Lipogenesis
Glucose
Liver
Genes
Enzymes
17 Citations (Scopus)

Prolonged atrial natriuretic peptide exposure stimulates guanylyl cyclase-A degradation

Flora, D. R. & Potter, L. R., Jun 1 2010, In : Endocrinology. 151, 6, p. 2769-2776 8 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Down-Regulation
Guanylate Cyclase
Guanylate Cyclase-Coupled Receptors
Hormones
35 Citations (Scopus)

Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response

Bandhakavi, S., Kim, Y-M., Ro, S. H., Xie, H., Onsongo, I. G., Jun, C. B., Kim, D-H. & Griffin, T. J., Feb 1 2010, In : Molecular and Cellular Proteomics. 9, 2, p. 403-414 12 p.

Research output: Contribution to journalArticle

Sirolimus
Proteomics
DNA Damage
DNA
Ataxia Telangiectasia
62 Citations (Scopus)

Quantitative proteomics reveals myosin and actin as promising saliva biomarkers for distinguishing pre-malignant and malignant oral lesions

de Jong, E., Xie, H., Onsongo, I. G., Stone, M. D., Chen, X. B., Kooren, J. A., Refsland, E. W., Griffin, R. J., Ondrey, F. G., Wu, B., Le, C. T., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., Aug 11 2010, In : PloS one. 5, 6, e11148.

Research output: Contribution to journalArticle

Biomarkers
Myosins
myosin
saliva
Saliva
70 Citations (Scopus)

Site mapping and characterization of O-glycan structures on α-dystroglycan isolated from rabbit skeletal muscle

Stalnaker, S. H., Hashmi, S., Lim, J. M., Aoki, K., Porterfield, M., Gutierrez-Sanchez, G., Wheeler, J., Ervasti, J. M., Bergmann, C., Tiemeyer, M. & Wells, L., Aug 6 2010, In : Journal of Biological Chemistry. 285, 32, p. 24882-24891 10 p.

Research output: Contribution to journalArticle

Dystroglycans
Tandem Mass Spectrometry
Glycosylation
Mass spectrometry
Polysaccharides
129 Citations (Scopus)

The actin gene family: Function follows isoform

Perrin, B. J. & Ervasti, J. M., Oct 1 2010, In : Cytoskeleton. 67, 10, p. 630-634 5 p.

Research output: Contribution to journalArticle

Actins
Protein Isoforms
Genes
Mammals
Amino Acid Sequence
2009
112 Citations (Scopus)

A dynamic range compression and three-dimensional peptide fractionation analysis platform expands proteome coverage and the diagnostic potential of whole saliva

Bandhakavi, S., Stone, M. D., Onsongo, I. G., Van Riper, S. K. & Griffin, T. J., Dec 4 2009, In : Journal of Proteome Research. 8, 12, p. 5590-5600 11 p.

Research output: Contribution to journalArticle

Proteome
Fractionation
Saliva
Peptides
Proteins
32 Citations (Scopus)

Biodesign of a renal-protective peptide based on alternative splicing of B-type natriuretic peptide

Pan, S., Chen, H. H., Dickey, D. M., Boerrigter, G., Lee, C., Kleppe, L. S., Hall, J. L., Lerman, A., Redfield, M. M., Potter, L. R., Burnett, J. C. & Simari, R. D., Jul 7 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 27, p. 11282-11287 6 p.

Research output: Contribution to journalArticle

Brain Natriuretic Peptide
Alternative Splicing
Kidney
Peptides
Glomerular Filtration Rate
25 Citations (Scopus)

Context-dependent functional substitution of α-skeletal actin by γ-cytoplasmic actin

Jaeger, M. A., Sonnemann, K. J., Fitzsimons, D. P., Prins, K. W. & Ervasti, J. M., Jul 1 2009, In : FASEB Journal. 23, 7, p. 2205-2214 10 p.

Research output: Contribution to journalArticle

Actins
Substitution reactions
Muscle
Muscles
Transgenic Mice
34 Citations (Scopus)

Dystrophin and utrophin have distinct effects on the structural dynamics of actin

Prochniewicz-Nakayama, E., Henderson, D., Ervasti, J. M. & Thomas, D. D., May 12 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 19, p. 7822-7827 6 p.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Actins
Anisotropy
Muscular Dystrophies
106 Citations (Scopus)

Dystrophin is a microtubule-associated protein

Prins, K. W., Humston, J. L., Mehta, A., Tate, V., Ralston, E. & Ervasti, J. M., Aug 10 2009, In : Journal of Cell Biology. 186, 3, p. 363-369 7 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubule-Associated Proteins
Microtubules
Tubulin
Costameres
63 Citations (Scopus)

Functional substitution by TAT-utrophin in dystrophin-deficient mice

Sonnemann, K. J., Heun-Johnson, H., Turner, A. J., Baltgalvis, K. A., Lowe, D. A. & Ervasti, J. M., May 1 2009, In : PLoS Medicine. 6, 5, e1000083.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Inbred mdx Mouse
Phenotype
Proteins
96 Citations (Scopus)

Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

Mi, N. L., Sang, H. H., Kim, J., Koh, A., Chang, S. L., Jung, H. K., Jeon, H., Kim, D-H., Suh, P. G. & Sung, H. R., Jul 1 2009, In : Molecular and cellular biology. 29, 14, p. 3991-4001 11 p.

Research output: Contribution to journalArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Sirolimus
Glucose
AMP-Activated Protein Kinases
Glyceraldehyde 3-Phosphate
60 Citations (Scopus)

Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor α activity

Sapiro, J. M., Mashek, M. T., Greenberg, A. S. & Mashek, D., Sep 14 2009, In : Journal of Lipid Research. 50, 8, p. 1621-1629 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Hydrolysis
Triglycerides
Liver
Proteins
1 Citation (Scopus)

Natriuretic Peptides

Bryan, P. M. & Potter, L. R., Feb 4 2009, Cardiovascular Hormone Systems. Wiley - VCH Verlag GmbH & CO. KGaA, p. 125-141 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

C-Type Natriuretic Peptide
Natriuretic Peptides
Brain Natriuretic Peptide
Atrial Natriuretic Factor
Heart Failure
83 Citations (Scopus)

Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells

Zhou, H., Shang, L., Li, X., Zhang, X., Gao, G., Guo, C., Chen, B., Liu, Q., Gong, Y. & Shao, C., Oct 15 2009, In : Experimental Cell Research. 315, 17, p. 2953-2962 10 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Catenins
Osteogenesis
Glycogen Synthase Kinase 3
resveratrol
15 Citations (Scopus)

Serum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner

Shang, L., Zhou, H., Xia, Y., Wang, H., Gao, G., Chen, B., Liu, Q., Shao, C. & Gong, Y., Oct 1 2009, In : Journal of Cellular and Molecular Medicine. 13, 10, p. 4176-4184 9 p.

Research output: Contribution to journalArticle

Up-Regulation
Gene Expression
Serum
NAD
Binding Sites