Research Output 1973 2019

2014
60 Citations (Scopus)

β-cell dysfunction due to increased ER stress in a stem cell model of wolfram syndrome

Shang, L., Hua, H., Foo, K., Martinez, H., Watanabe, K., Zimmer, M., Kahler, D. J., Freeby, M., Chung, W., LeDuc, C., Goland, R., Leibel, R. L. & Egli, D., Mar 1 2014, In : Diabetes. 63, 3, p. 923-933 11 p.

Research output: Contribution to journalArticle

Wolfram Syndrome
Endoplasmic Reticulum Stress
Stem Cells
Insulin
Optic Atrophy
2013
17 Citations (Scopus)

Actin Isoforms in Neuronal Development and Function

Cheever, T. R. & Ervasti, J. M., Jan 1 2013, International Review of Cell and Molecular Biology. Elsevier Inc., p. 157-213 57 p. (International Review of Cell and Molecular Biology; vol. 301).

Research output: Chapter in Book/Report/Conference proceedingChapter

Actins
Protein Isoforms
Actin Cytoskeleton
Neurons
Nervous System Diseases
14 Citations (Scopus)

A human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B

Robinson, J. W., Dickey, D. M., Miura, K., Michigami, T., Ozono, K. & Potter, L. R., Oct 1 2013, In : Bone. 56, 2, p. 375-382 8 p.

Research output: Contribution to journalArticle

Guanylate Cyclase
C-Type Natriuretic Peptide
Mutation
Adenosine Triphosphate
Phosphorylation
4 Citations (Scopus)

Algal swimming velocities signal fatty acid accumulation

Hansen, T. J., Hondzo, M., Mashek, M. T., Mashek, D. & Lefebvre, P. A., Jan 1 2013, In : Biotechnology and Bioengineering. 110, 1, p. 143-152 10 p.

Research output: Contribution to journalArticle

Fatty acids
Fatty Acids
Biofuels
Nutrients
RNA Sequence Analysis
93 Citations (Scopus)

A two-step database search method improves sensitivity in peptide sequence matches for metaproteomics and proteogenomics studies

Jagtap, P. D., Goslinga, J., Kooren, J. A., Mcgowan, T., Wroblewski, M. S., Seymour, S. L. & Griffin, T. J., Apr 1 2013, In : Proteomics. 13, 8, p. 1352-1357 6 p.

Research output: Contribution to journalArticle

Databases
Peptides
Proteogenomics
Proteomics
Proteins
65 Citations (Scopus)

Compound loss of muscleblind-like function in myotonic dystrophy

Lee, K. Y., Li, M., Manchanda, M., Batra, R., Charizanis, K., Mohan, A., Warren, S. A., Chamberlain, C. M., Finn, D., Hong, H., Ashraf, H., Kasahara, H., Ranum, L. P. W. & Swanson, M. S., Jan 1 2013, In : EMBO Molecular Medicine. 5, 12, p. 1887-1900 14 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
RNA
Skeletal Muscle
Myocardium
Myotonia
33 Citations (Scopus)

Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes

Ro, S. H., Jung, C. H., Hahn, W. S., Xu, X., Kim, Y-M., Yun, Y. S., Park, J-M., KIM, KWAN. HYUN., Seo, M., Ha, T. Y., Arriaga, E., Bernlohr, D. A. & Kim, D-H., Dec 1 2013, In : Autophagy. 9, 12, p. 2103-2114 12 p.

Research output: Contribution to journalArticle

Autophagy
Lipid Metabolism
Adipocytes
Adipogenesis
Glucose
8 Citations (Scopus)

DRAGging amino Acid-mTORC1 signaling by SH3BP4

Kim, Y. M. & Kim, D. H., Jan 1 2013, In : Molecules and cells. 35, 1, p. 1-6 6 p.

Research output: Contribution to journalReview article

GTP Phosphohydrolases
Carrier Proteins
Amino Acids
Intercellular Signaling Peptides and Proteins
Tuberous Sclerosis
128 Citations (Scopus)

Engineering bone tissue substitutes from human induced pluripotent stem cells

De Peppo, G. M., Marcos-Campos, I., Kahler, D. J., Alsalman, D., Shang, L., Vunjak-Novakovic, G. & Marolt, D., May 21 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 21, p. 8680-8685 6 p.

Research output: Contribution to journalArticle

Bone Substitutes
Induced Pluripotent Stem Cells
Bone and Bones
Bioreactors
Perfusion

Erratum: Statement of retraction (Diabetes (2012) 61 (3114-3125))

Zhang, W., Zhang, X., Wang, H., Guo, X., Li, H., Wang, Y., Xu, X., Tan, L., Mashek, M. T., Zhang, C., Chen, Y., Mashek, D., Foretz, M., Zhu, C., Zhou, H., Liu, X., Viollet, B., Wu, C. & Huo, Y., Mar 1 2013, In : Diabetes. 62, 3, 1 p.

Research output: Contribution to journalComment/debate

28 Citations (Scopus)

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

Ong, K. T., Mashek, M. T., Bu, S. Y. & Mashek, D., Jan 1 2013, In : FASEB Journal. 27, 1, p. 313-321 9 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Lipase
Liver
Triglycerides
Glucose
42 Citations (Scopus)

Hepatic fatty acid trafficking: Multiple forks in the road

Mashek, D., Jan 1 2013, In : Advances in Nutrition. 4, 6, p. 697-710 14 p.

Research output: Contribution to journalReview article

roads
Fatty Acids
fatty acids
liver
Liver
22 Citations (Scopus)

Identification of New Dystroglycan Complexes in Skeletal Muscle

Johnson, E. K., Li, B., Yoon, J. H., Flanigan, K. M., Martin, P. T., Ervasti, J. M. & Montanaro, F., Aug 8 2013, In : PloS one. 8, 8, e73224.

Research output: Contribution to journalArticle

Dystroglycans
dystrophin
Dystrophin
Muscle
skeletal muscle
19 Citations (Scopus)

Mass spectrometry-based proteomics: Basic principles and emerging technologies and directions

Van Riper, S. K., de Jong, E., Carlis, J. V. & Griffin, T. J., Jan 1 2013, Radiation Proteomics: The Effects of Ionizing and Non-Ionizing Radiation on Cells and Tissues. Springer New York LLC, p. 1-35 35 p. (Advances in Experimental Medicine and Biology; vol. 990).

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteomics
Mass spectrometry
Mass Spectrometry
Technology
Biological radiation effects

Natriuretic Peptides, Their Receptors and Therapeutic Applications

Barbieri, K. & Potter, L. R., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 225-228 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Natriuretic Peptides
Peptide Receptors
Guanylate Cyclase-Coupled Receptors
C-Type Natriuretic Peptide
Hormones
6 Citations (Scopus)

New lipid-producing, cold-tolerant yellow-green alga isolated from the rocky mountains of Colorado

Nelson, D. R., Mengistu, S., Ranum, P., Celio, G., Mashek, M., Mashek, D. & Lefebvre, P. A., Jul 1 2013, In : Biotechnology Progress. 29, 4, p. 853-861 9 p.

Research output: Contribution to journalArticle

Chlorophyta
Lipids
Axenic Culture
Snow
Temperature
15 Citations (Scopus)

Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma

Hong, S. M., Park, C. W., Cha, H. J., Kwon, J. H., Yun, Y. S., Lee, N. G., Kim, D. G., Nam, H. G. & Choi, K. Y., Feb 1 2013, In : Clinical and Experimental Metastasis. 30, 2, p. 177-187 11 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Sirolimus
Down-Regulation
Neoplasms
Epithelium

The proteome of human saliva

Griffin, T. J., Aug 12 2013, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring III. Vol. 8723. 87230A

Research output: Chapter in Book/Report/Conference proceedingConference contribution

proteome
saliva
Proteome
Proteins
Protein
13 Citations (Scopus)

Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells

Mamedova, L. K., Yuan, K., Laudick, A. N., Fleming, S. D., Mashek, D. & Bradford, B. J., Aug 1 2013, In : Journal of Nutritional Biochemistry. 24, 8, p. 1499-1507 9 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 4
Palmitates
Gene expression
Hepatocytes
Carcinoma
36 Citations (Scopus)

β-actin and fascin-2 cooperate to maintain stereocilia length

Perrin, B. J., Strandjord, D. M., Narayanan, P., Henderson, D. M., Johnson, K. R. & Ervasti, J. M., May 13 2013, In : Journal of Neuroscience. 33, 19, p. 8114-8121 8 p.

Research output: Contribution to journalArticle

Stereocilia
Actins
Auditory Hair Cells
Actin Cytoskeleton
fascin
2012
29 Citations (Scopus)

AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity

Zhang, W., Zhang, X., Wang, H., Guo, X., Li, H., Wang, Y., Xu, X., Tan, L., Mashek, M. T., Zhang, C., Chen, Y., Mashek, D., Foretz, M., Zhu, C., Zhou, H., Liu, X., Viollet, B., Wu, C. & Huo, Y., Dec 1 2012, In : Diabetes. 61, 12, p. 3114-3125 12 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Insulin Resistance
Obesity
Diet
High Fat Diet
36 Citations (Scopus)

Crystal structure of the Gtr1pGTP-Gtr2pGDP protein complex reveals large structural rearrangements triggered by GTP-to-GDP conversion

Jeong, J. H., Lee, K. H., Kim, Y-M., Kim, D-H., Oh, B. H. & Kim, Y. G., Aug 24 2012, In : Journal of Biological Chemistry. 287, 35, p. 29648-29653 6 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Raptors
Guanosine Triphosphate
Crystal structure
Proteins
52 Citations (Scopus)

Deep metaproteomic analysis of human salivary supernatant

Jagtap, P. D., Mcgowan, T., Bandhakavi, S., Tu, Z. J., Seymour, S., Griffin, T. J. & Rudney, J. D., Apr 1 2012, In : Proteomics. 12, 7, p. 992-1001 10 p.

Research output: Contribution to journalArticle

Proteome
Peptides
Proteins
Mouth Diseases
Selenomonas

Emerging non-invasively collected genomic and proteomic biomarkers for the early diagnosis of oral squamous cell carcinoma (OSCC)

Kooren, J. A., Rhodus, N. L. & Griffin, T. J., Dec 1 2012, Squamous Cell Carcinoma. Nova Science Publishers, Inc., p. 197-210 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biomarkers
Proteomics
Mouth Neoplasms
Early Diagnosis
Squamous Cell Carcinoma
28 Citations (Scopus)

Fibroblast Growth Factor Receptor 1 Activation in Mammary Tumor Cells Promotes Macrophage Recruitment in a CX3CL1-Dependent Manner

Reed, J. R., Stone, M. D., Beadnell, T. C., Ryu, Y., Griffin, T. J. & Schwertfeger, K., Sep 24 2012, In : PloS one. 7, 9, e45877.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 1
Macrophages
mammary neoplasms (animal)
Tumors
macrophages
17 Citations (Scopus)

Galbanic acid decreases androgen receptor abundance and signaling and induces G 1 arrest in prostate cancer cells

Zhang, Y., KIM, KWAN. HYUN., Zhang, W., Guo, Y., Kim, S. H. & Lü, J., Jan 11 2012, In : International Journal of Cancer. 130, 1, p. 200-212 13 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
galbanic acid
Ferula
Growth
17 Citations (Scopus)
Guanylate Cyclase
Cardiac Myocytes
Atrial Natriuretic Factor
Membranes
atrial natriuretic factor receptor A
21 Citations (Scopus)

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain

Robinson, J. W. & Potter, L. R., Sep 4 2012, In : Science Signaling. 5, 240, ra65.

Research output: Contribution to journalArticle

Dimers
Natriuretic Peptides
Guanosine Triphosphate
Catalytic Domain
Adenosine Triphosphate
13 Citations (Scopus)

Impacts of dystrophin and utrophin domains on actin structural dynamics: Implications for therapeutic design

Lin, A. Y., Prochniewicz-Nakayama, E., Henderson, D. M., Li, B., Ervasti, J. M. & Thomas, D. D., Jun 29 2012, In : Journal of Molecular Biology. 420, 1-2, p. 87-98 12 p.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Actins
Anisotropy
Genetic Therapy
84 Citations (Scopus)

Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes

Robinson, J. W., Zhang, M., Shuhaibar, L. C., Norris, R. P., Geerts, A., Wunder, F., Eppig, J. J., Potter, L. R. & Jaffe, L. A., Jun 15 2012, In : Developmental Biology. 366, 2, p. 308-316 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Ovarian Follicle
Peptide Receptors
Guanylate Cyclase
Cyclic GMP
36 Citations (Scopus)

Mouse model of muscleblind-like 1 overexpression: Skeletal muscle effects and therapeutic promise

Chamberlain, C. M. & Ranum, L. P. W., Nov 1 2012, In : Human molecular genetics. 21, 21, p. 4645-4654 10 p., dds306.

Research output: Contribution to journalArticle

Alternative Splicing
Therapeutic Uses
Skeletal Muscle
Myotonia
Myotonic Dystrophy
117 Citations (Scopus)

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

Zhang, D. S., Piazza, V., Perrin, B. J., Rzadzinska, A. K., Poczatek, J. C., Wang, M., Prosser, H. M., Ervasti, J. M., Corey, D. P. & Lechene, C. P., Jan 26 2012, In : Nature. 481, 7382, p. 520-524 5 p.

Research output: Contribution to journalArticle

Stereocilia
Isotopes
Hair
Mass Spectrometry
Actins
18 Citations (Scopus)

Online nanoscale ERLIC-MS outperforms RPLC-MS for shotgun proteomics in complex mixtures

de Jong, E. & Griffin, T. J., Oct 5 2012, In : Journal of Proteome Research. 11, 10, p. 5059-5064 6 p.

Research output: Contribution to journalArticle

Firearms
Chromatography
Complex Mixtures
Static Electricity
Hydrophobic and Hydrophilic Interactions
79 Citations (Scopus)

Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice

Guo, X., Li, H., Xu, H., Halim, V., Zhang, W., Wang, H., Ong, K. T., Woo, S. L., Walzem, R. L., Mashek, D., Dong, H., Lu, F., Wei, L., Huo, Y. & Wu, C., Jun 29 2012, In : PloS one. 7, 6, e39286.

Research output: Contribution to journalArticle

fatty liver
Fatty Liver
Liver
fatty-acid synthase
inflammation
42 Citations (Scopus)

Protein carbonylation and adipocyte mitochondrial function

Curtis, J. M., Hahn, W. S., Stone, M. D., Inda, J. J., Droullard, D. J., Kuzmicic, J. P., Donoghue, M. A., Long, E. K., Armien, A. G., Lavandero, S., Arriaga, E., Griffin, T. J. & Bernlohr, D. A., Sep 21 2012, In : Journal of Biological Chemistry. 287, 39, p. 32967-32980 14 p.

Research output: Contribution to journalArticle

Protein Carbonylation
Carbonylation
Adipocytes
Phosphate Transport Proteins
NADH Dehydrogenase
23 Citations (Scopus)

Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain

Cheever, T. R., Li, B. & Ervasti, J. M., Mar 5 2012, In : PloS one. 7, 3, e32970.

Research output: Contribution to journalArticle

Ablation
actin
Actins
Brain
brain
11 Citations (Scopus)

Scaling up multi-touch selection and querying: Interfaces and applications for combining mobile multi-touch input with large-scale visualization displays

Keefe, D. F., Gupta, A., Feldman, D., Carlis, J. V., Krehbiel Keefe, S. & Griffin, T. J., Oct 1 2012, In : International Journal of Human Computer Studies. 70, 10, p. 703-713 11 p.

Research output: Contribution to journalArticle

scaling
visualization
Visualization
Display devices
Biochemistry
48 Citations (Scopus)

SH3BP4 Is a Negative Regulator of Amino Acid-Rag GTPase-mTORC1 Signaling

Kim, Y-M., Stone, M., Hwang, T. H., Kim, Y. G., Dunlevy, J. R., Griffin, T. J. & Kim, D-H., Jun 29 2012, In : Molecular Cell. 46, 6, p. 833-846 14 p.

Research output: Contribution to journalArticle

src Homology Domains
Guanosine
Carrier Proteins
Amino Acids
Autophagy
31 Citations (Scopus)

Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses

Huo, Y., Guo, X., Li, H., Xu, H., Halim, V., Zhang, W., Wang, H., Fan, Y. Y., Ong, K. T., Woo, S. L., Chapkin, R. S., Mashek, D., Chen, Y., Dong, H., Lu, F., Wei, L. & Wu, C., Jun 15 2012, In : Journal of Biological Chemistry. 287, 25, p. 21492-21500 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Nutrition
Liver
Transgenic Mice
Insulin Resistance
12 Citations (Scopus)

The carboxy-terminal third of dystrophin enhances actin binding activity

Henderson, D. M., Lin, A. Y., Thomas, D. D. & Ervasti, J. M., Feb 24 2012, In : Journal of Molecular Biology. 416, 3, p. 414-424 11 p.

Research output: Contribution to journalArticle

Dystrophin
Actins
Microfilament Proteins
Anisotropy
Actin Cytoskeleton
3 Citations (Scopus)

Using Representational Difference Analysis to detect changes in transcript expression of Aiptasia genes after laboratory exposure to lindane

Morgan, M. B., Parker, C. C., Robinson, J. W. & Pierce, E. M., Apr 1 2012, In : Aquatic Toxicology. 110-111, p. 66-73 8 p.

Research output: Contribution to journalArticle

Cnidaria
Lindane
lindane
HCH
Anemone
2011
174 Citations (Scopus)

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

Ong, K. T., Mashek, M. T., Bu, S. Y., Greenberg, A. S. & Mashek, D., Jan 1 2011, In : Hepatology. 53, 1, p. 116-126 11 p.

Research output: Contribution to journalArticle

Lipase
Fatty Acids
Liver
Peroxisome Proliferator-Activated Receptors
Triglycerides
6 Citations (Scopus)
Cell Tracking
Atrial Natriuretic Factor
Ligands
Antibodies
HeLa Cells
9 Citations (Scopus)
Staurosporine
Guanylate Cyclase
Guanosine Triphosphate
Adenosine Triphosphate
Guanylate Cyclase-Coupled Receptors
35 Citations (Scopus)

Axonal regeneration and neuronal function are preserved in motor neurons lacking ß-actin In Vivo

Cheever, T. R., Olson, E. A. & Ervasti, J. M., Mar 28 2011, In : PloS one. 6, 3, e17768.

Research output: Contribution to journalArticle

Motor Neurons
motor neurons
Neurons
actin
Actins
Clostridium
Ethanol
Genes
Protein folding
Bacteria
46 Citations (Scopus)
Natriuretic Peptides
Brain Natriuretic Peptide
Atrial Natriuretic Factor
Neprilysin
Guanylate Cyclase
4 Citations (Scopus)

Dynamic range compression: A solution for proteomic biomarker discovery?

Griffin, T. J. & Bandhakavi, S., Sep 1 2011, In : Bioanalysis. 3, 18, p. 2053-2056 4 p.

Research output: Contribution to journalReview article

Body fluids
Body Fluids
Biomarkers
Post Translational Protein Processing
Proteomics
45 Citations (Scopus)

Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism

Schwinkendorf, D. R., Tsatsos, N. G., Gosnell, B. A. & Mashek, D., Mar 1 2011, In : International Journal of Obesity. 35, 3, p. 336-344 9 p.

Research output: Contribution to journalArticle

Neuropeptides
Energy Metabolism
Fatty Acids
Oleic Acid
Eating
11 Citations (Scopus)
Mouth Neoplasms
Biomarkers
Exudates and Transudates
Tumor Biomarkers
Proteomics