Research Output 1973 2019

Article
14 Citations (Scopus)

Evidence for a common component in kinetically distinct transport systems of Saccharomyces cerevisiae

Roon, R. J., Meyer, G. M. & Larimore, F. S., Jan 1 1977, In : MGG Molecular & General Genetics. 158, 2, p. 185-191 7 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Amino Acid Transport Systems
Ionophores
Ammonia
Adenosine Triphosphatases
28 Citations (Scopus)

Fibroblast Growth Factor Receptor 1 Activation in Mammary Tumor Cells Promotes Macrophage Recruitment in a CX3CL1-Dependent Manner

Reed, J. R., Stone, M. D., Beadnell, T. C., Ryu, Y., Griffin, T. J. & Schwertfeger, K. L., Sep 24 2012, In : PloS one. 7, 9, e45877.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 1
Macrophages
mammary neoplasms (animal)
Tumors
macrophages
63 Citations (Scopus)

Functional substitution by TAT-utrophin in dystrophin-deficient mice

Sonnemann, K. J., Heun-Johnson, H., Turner, A. J., Baltgalvis, K. A., Lowe, D. A. & Ervasti, J. M., May 1 2009, In : PLoS medicine. 6, 5, e1000083.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Inbred mdx Mouse
Phenotype
Proteins
3 Citations (Scopus)

GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

Grunwald, D. S., Otto, N. M., Park, J-M., Song, D. & Kim, D-H., Jan 1 2019, In : Autophagy.

Research output: Contribution to journalArticle

Autophagy
Microtubule-Associated Proteins
GABA-A Receptors
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
18 Citations (Scopus)

Galbanic acid decreases androgen receptor abundance and signaling and induces G 1 arrest in prostate cancer cells

Zhang, Y., KIM, KWAN. HYUN., Zhang, W., Guo, Y., Kim, S. H. & Lü, J., Jan 11 2012, In : International Journal of Cancer. 130, 1, p. 200-212 13 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
galbanic acid
Ferula
Growth
30 Citations (Scopus)

Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemia

McFalls, E. O., Murad, B., Liow, J. S., Gannon, M. C., Haspel, H. C., Lange, A. J., Marx, D., Sikora, J. & Ward, H. B., Jun 29 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 282, 1 51-1

Research output: Contribution to journalArticle

Glycogen
Swine
Ischemia
Glucose
Hexokinase
54 Citations (Scopus)

Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide dependent enzyme from Saccharomyces cerevisiae

Roon, R. J., Even, H. L. & Larimore, F., Dec 1 1974, In : Journal of bacteriology. 118, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Glutamate Synthase
Glutamate Dehydrogenase
Glutamine
NAD
Glutamate Synthase (NADH)
97 Citations (Scopus)

Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

Mi, N. L., Sang, H. H., Kim, J., Koh, A., Chang, S. L., Jung, H. K., Jeon, H., Kim, D. H., Suh, P. G. & Sung, H. R., Jul 1 2009, In : Molecular and cellular biology. 29, 14, p. 3991-4001 11 p.

Research output: Contribution to journalArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Sirolimus
Glucose
AMP-Activated Protein Kinases
Glyceraldehyde 3-Phosphate
17 Citations (Scopus)
Guanylate Cyclase
Cardiac Myocytes
Atrial Natriuretic Factor
Membranes
atrial natriuretic factor receptor A
21 Citations (Scopus)

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain

Robinson, J. W. & Potter, L. R., Sep 4 2012, In : Science signaling. 5, 240, ra65.

Research output: Contribution to journalArticle

Dimers
Natriuretic Peptides
Guanosine Triphosphate
Catalytic Domain
Adenosine Triphosphate
53 Citations (Scopus)

Gypenosides protect primary cultures of rat cortical cells against oxidative neurotoxicity

Shang, L., Liu, J., Zhu, Q., Zhao, L., Feng, Y., Wang, X., Cao, W. & Xin, H., Aug 2 2006, In : Brain Research. 1102, 1, p. 163-174 12 p.

Research output: Contribution to journalArticle

Glutamic Acid
Oxidative Stress
Cell Death
gypenoside
Apoptosis
8 Citations (Scopus)

GβL regulates TNFα-induced NF-k{cyrillic}B signaling by directly inhibiting the activation of Ik{cyrillic}B kinase

Kim, Y. L., Kim, J. E., Shin, K. J., Lee, S., Ahn, C., Chung, J., Kim, D. H., Seong, J. Y. & Hwang, J. I., Nov 1 2008, In : Cellular Signalling. 20, 11, p. 2127-2133 7 p.

Research output: Contribution to journalArticle

Leucine Zippers
Small Interfering RNA
Transcriptional Activation
Phosphotransferases
Down-Regulation
28 Citations (Scopus)

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

Ong, K. T., Mashek, M. T., Bu, S. Y. & Mashek, D. G., Jan 1 2013, In : FASEB Journal. 27, 1, p. 313-321 9 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Lipase
Liver
Triglycerides
Glucose
23 Citations (Scopus)

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism

Ong, K. T., Mashek, M. T., Davidson, N. O. & Mashek, D. G., May 2014, In : Journal of Lipid Research. 55, 5, p. 808-815 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Lipase
Liver
Carrier Proteins
Fatty Acids
42 Citations (Scopus)

Hepatic lipid droplet biology: Getting to the root of fatty liver

Mashek, D. G., Khan, S. A., Sathyanarayan, A., Ploeger, J. M. & Franklin, M. P., Sep 1 2015, In : Hepatology. 62, 3, p. 964-967 4 p.

Research output: Contribution to journalArticle

Fatty Liver
Liver
Lipids
Organelles
Liver Diseases
60 Citations (Scopus)

Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways

Bu, S. Y. & Mashek, D., Nov 1 2010, In : Journal of Lipid Research. 51, 11, p. 3270-3280 11 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Fatty Acids
Liver
Fatty Acid Transport Proteins
RNA Interference
60 Citations (Scopus)

Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor α activity

Sapiro, J. M., Mashek, M. T., Greenberg, A. S. & Mashek, D. G., Sep 14 2009, In : Journal of Lipid Research. 50, 8, p. 1621-1629 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Hydrolysis
Triglycerides
Liver
Proteins
105 Citations (Scopus)

Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature

Olney, R. C., Bükülmez, H., Bartels, C. F., Prickett, T. C. R., Espiner, E. A., Potter, L. R. & Warman, M. L., Apr 1 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 4, p. 1229-1232 4 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Mutation
Insulin-Like Growth Factor I
Genes
Plasmas
34 Citations (Scopus)

Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature

Wang, S. R., Jacobsen, C. M., Carmichael, H., Edmund, A. B., Robinson, J. W., Olney, R. C., Miller, T. C., Moon, J. E., Mericq, V., Potter, L. R., Warman, M. L., Hirschhorn, J. N. & Dauber, A., Apr 1 2015, In : Human mutation. 36, 4, p. 474-481 8 p.

Research output: Contribution to journalArticle

Mutation
Haploinsufficiency
Genes
Observation
atrial natriuretic factor receptor B
34 Citations (Scopus)

Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva

Bandhakavi, S., Van Riper, S. K., Tawfik, P. N., Stone, M. D., Haddad, T., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., Mar 4 2011, In : Journal of Proteome Research. 10, 3, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

Pulse time modulation
Saliva
Libraries
Workflow
Proteins
6 Citations (Scopus)

High-Affinity Transport of L-Glutamine by a Plasma Membrane Preparation from Rat Brain

Roon, R. J., Shofner, S. A. & Koerner, J. F., Jan 1 1989, In : Biochemistry. 28, 20, p. 8083-8087 5 p.

Research output: Contribution to journalArticle

Cell membranes
Glutamine
Rats
Brain
Cell Membrane
6 Citations (Scopus)

High frequency hearing loss and hyperactivity in DUX4 transgenic mice

Dandapat, A., Perrin, B. J., Cabelka, C., Razzoli, M., Ervasti, J. M., Bartolomucci, A., Lowe, D. A. & Kyba, M., Mar 2016, In : PloS one. 11, 3, e0151467.

Research output: Contribution to journalArticle

High-Frequency Hearing Loss
Audition
hearing
Transgenic Mice
Doxycycline
29 Citations (Scopus)

Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis

Bandhakavi, S., Xie, H., O'Callaghan, B., Sakurai, H., Kim, D. H. & Griffin, T. J., Feb 13 2008, In : PloS one. 3, 2, e1598.

Research output: Contribution to journalArticle

Oxidative stress
Sirolimus
Proteomics
proteomics
Yeast
19 Citations (Scopus)

Human B-type natriuretic peptide is not degraded by meprin A

Dickey, D. M. & Potter, L. R., Oct 1 2010, In : Biochemical Pharmacology. 80, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

meprin A
Brain Natriuretic Peptide
Rats
Neprilysin
Membranes
8 Citations (Scopus)

Identification and characterization of the ATP-binding site in human pancreatic glucokinase

Marotta, D. E., Anand, G. R., Anderson, T. A., Miller, S. P., Okar, D. A., Levitt, D. G. & Lange, A. J., Apr 1 2005, In : Archives of Biochemistry and Biophysics. 436, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

Glucokinase
Adenosine Triphosphate
Binding Sites
Glucose
Adenosine Diphosphate Glucose
101 Citations (Scopus)
Muscle Mitochondrion
Isotope Labeling
Affinity chromatography
Mitochondria
Tandem Mass Spectrometry
22 Citations (Scopus)

Identification of New Dystroglycan Complexes in Skeletal Muscle

Johnson, E. K., Li, B., Yoon, J. H., Flanigan, K. M., Martin, P. T., Ervasti, J. & Montanaro, F., Aug 8 2013, In : PloS one. 8, 8, e73224.

Research output: Contribution to journalArticle

Dystroglycans
dystrophin
Dystrophin
Muscle
skeletal muscle
13 Citations (Scopus)

Impacts of dystrophin and utrophin domains on actin structural dynamics: Implications for therapeutic design

Lin, A. Y., Prochniewicz-Nakayama, E., Henderson, D. M., Li, B., Ervasti, J. M. & Thomas, D. D., Jun 29 2012, In : Journal of Molecular Biology. 420, 1-2, p. 87-98 12 p.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Actins
Anisotropy
Genetic Therapy
5 Citations (Scopus)

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms

O'Rourke, A. R., Lindsay, A., Tarpey, M. D., Yuen, S., McCourt, P., Nelson, D. M., Perrin, B. J., Thomas, D. D., Spangenburg, E. E., Lowe, D. A. & Ervasti, J. M., Feb 2018, In : FEBS Journal. 285, 3, p. 481-500 20 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Dynamics
Muscle Relaxation
Ablation
Muscle
Actins
4 Citations (Scopus)

Improved intensity-based label-free quantification via proximity-based intensity normalization (PIN)

Van Riper, S. K., de Jong, E., Higgins, L., Carlis, J. V. & Griffin, T. J., Mar 7 2014, In : Journal of Proteome Research. 13, 3, p. 1281-1292 12 p.

Research output: Contribution to journalArticle

Labels
Workflow
High Pressure Liquid Chromatography
Molecules
Proteins
26 Citations (Scopus)

Improved Methods for Reprogramming Human Dermal Fibroblasts Using Fluorescence Activated Cell Sorting

Kahler, D. J., Ahmad, F. S., Ritz, A., Hua, H., Moroziewicz, D. N., Sproul, A. A., Dusenberry, C. R., Shang, L., Paull, D., Zimmer, M., Weiss, K. A., Egli, D. & Noggle, S. A., Mar 29 2013, In : PloS one. 8, 3, e59867.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Fibroblasts
Stem cells
Sorting
fibroblasts
Open Access
Galaxies
Workflow
Software
Processing
Research Personnel
17 Citations (Scopus)

Independent variability of microtubule perturbations associated with dystrophinopathy

Belanto, J. J., Olthoff, J. T., Mader, T. L., Chamberlain, C. M., Nelson, D. M., McCourt, P. M., Talsness, D. M., Gundersen, G. G., Lowe, D. A. & Ervasti, J. M., Nov 15 2016, In : Human molecular genetics. 25, 22, p. 4951-4961 11 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubules
Inbred mdx Mouse
Utrophin
Tubulin
36 Citations (Scopus)

Inhibition of amino acid transport by ammonium ion in Saccharomyces cerevisiae

Roon, R. J., Larimore, F. & Levy, J. S., Dec 1 1975, In : Journal of bacteriology. 124, 1, p. 325-331 7 p.

Research output: Contribution to journalArticle

Ion Transport
Ammonium Sulfate
Ammonium Compounds
Saccharomyces cerevisiae
Cycloheximide
26 Citations (Scopus)
Phosphofructokinase-2
Glucokinase
AMP-Activated Protein Kinases
Phosphorylation
Glucose
43 Citations (Scopus)

Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response

Ralat, L. A., Guo, Q., Ren, M., Funke, T., Dickey, D. M., Potter, L. R. & Tang, W. J., Feb 11 2011, In : Journal of Biological Chemistry. 286, 6, p. 4670-4679 10 p.

Research output: Contribution to journalArticle

Insulysin
Natriuretic Peptides
Atrial Natriuretic Factor
Cyclic GMP
Cyclic Peptides
755 Citations (Scopus)

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Haar, E. V., Lee, S. I., Bandhakavi, S., Griffin, T. J. & Kim, D. H., Mar 1 2007, In : Nature Cell Biology. 9, 3, p. 316-323 8 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Sirolimus
Proline
Insulin
Tuberous Sclerosis
20 Citations (Scopus)

Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins

Zhang, W., Bu, S. Y., Mashek, M. T., O-Sullivan, I. S., Sibai, Z., Khan, S. A., Ilkayeva, O., Newgard, C. B., Mashek, D. G. & Unterman, T. G., Apr 12 2016, In : Cell reports. 15, 2, p. 349-359 11 p.

Research output: Contribution to journalArticle

Lipase
Lipid Metabolism
Metabolism
Lipolysis
Lipids

Integrative effects of dystrophin loss on metabolic function of the mdx mouse

Strakova, J., Kamdar, F., Kulhanek, D., Razzoli, M., Garry, D. J., Ervasti, J. M., Bartolomucci, A. & Townsend, D. W., Dec 1 2018, In : Scientific reports. 8, 1, 13624.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Dystrophin
Duchenne Muscular Dystrophy
Skeletal Muscle
Fats
29 Citations (Scopus)

Internal deletion compromises the stability of dystrophin

Henderson, D. M., Belanto, J. J., Li, B., Heun-Johnson, H. & Ervasti, J. M., Aug 1 2011, In : Human molecular genetics. 20, 15, p. 2955-2963 9 p., ddr199.

Research output: Contribution to journalArticle

Dystrophin
Utrophin
Freezing
Proteins
Duchenne Muscular Dystrophy
85 Citations (Scopus)

Investigation of in vivo fatty acid metabolism in AFABP/aP2-/- mice

Baar, R. A., Dingfelder, C. S., Smith, L. A., Bernlohr, D. A., Wu, C., Lange, A. J. & Parks, E. J., Jan 1 2005, In : American Journal of Physiology - Endocrinology and Metabolism. 288, 1 51-1, p. E187-E193

Research output: Contribution to journalArticle

Nonesterified Fatty Acids
Fatty Acids
Serum
Liver
Glucose
23 Citations (Scopus)

Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor γ activation in mice

Guo, X., Xu, K., Zhang, J., Li, H., Zhang, W., Wang, H., Lange, A. J., Chen, Y. E., Huo, Y. & Wu, C., Jul 30 2010, In : Journal of Biological Chemistry. 285, 31, p. 23711-23720 10 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Peroxisome Proliferator-Activated Receptors
Chemical activation
Adipocytes
Insulin
62 Citations (Scopus)

IPSC-derived β cells model diabetes due to glucokinase deficiency

Hua, H., Shang, L., Martinez, H., Freeby, M., Gallagher, M. P., Ludwig, T., Deng, L., Greenberg, E., LeDuc, C., Chung, W. K., Goland, R., Leibel, R. L. & Egli, D., Jul 1 2013, In : Journal of Clinical Investigation. 123, 7, p. 3146-3153 8 p.

Research output: Contribution to journalArticle

Glucokinase
Induced Pluripotent Stem Cells
Insulin
Phenotype
Stem Cells
15 Citations (Scopus)

Iron-sparing response of mycobacterium avium subsp. paratuberculosis is strain dependent

Janagama, H. K., Senthilkumar, Bannantine, J. P., Kugadas, A., Jagtap, P., Higgins, L., Witthuhn, B. A. & Sreevatsan, S., Oct 26 2010, In : BMC microbiology. 10, 268.

Research output: Contribution to journalArticle

Paratuberculosis
Mycobacterium avium
Iron
Metabolic Networks and Pathways
Proteomics
1 Citation (Scopus)

Isometric resistance training increases strength and alters histopathology of dystrophin-deficient mouse skeletal muscle

Lindsay, A., Larson, A. A., Verma, M., Ervasti, J. M. & Lowe, D. A., Feb 1 2019, In : Journal of applied physiology. 126, 2, p. 363-375 13 p.

Research output: Contribution to journalArticle

Open Access
Dystrophin
Resistance Training
Duchenne Muscular Dystrophy
Skeletal Muscle
Muscles
120 Citations (Scopus)

iTRAQ reagent-based quantitative proteomic analysis on a linear ion trap mass spectrometer

Griffin, T. J., Xie, H., Bandhakavi, S., Popko, J., Mohan, A., Carlis, J. V. & Higgins, L., Nov 1 2007, In : Journal of Proteome Research. 6, 11, p. 4200-4209 10 p.

Research output: Contribution to journalArticle

Mass spectrometers
Proteomics
Ions
Peptides
Software
34 Citations (Scopus)

Large-scale phosphoproteomics analysis of whole saliva reveals a distinct phosphorylation pattern

Stone, M. D., Chen, X., McGowan, T., Bandhakavi, S., Cheng, B., Rhodus, N. L. & Griffin, T. J., Apr 1 2011, In : Journal of Proteome Research. 10, 4, p. 1728-1736 9 p.

Research output: Contribution to journalArticle

Phosphorylation
Phosphoproteins
Saliva
Salivary Proteins and Peptides
Phosphotransferases
34 Citations (Scopus)

L Asparaginase of Saccharomyces cerevisiae: an extracellular enzyme

Dunlop, P. C. & Roon, R. J., Dec 1 1975, In : Journal of bacteriology. 122, 3, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

Hydroxymercuribenzoates
Species Specificity
Asparaginase
Stereoisomerism
Cell-Free System
46 Citations (Scopus)

Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-γ activation and function in lipid homeostasis and energy expenditure

Jin, D., Guo, H., Bu, S. Y., Zhang, Y., Hannaford, J., Mashek, D. & Chen, X., Feb 1 2011, In : FASEB Journal. 25, 2, p. 754-764 11 p.

Research output: Contribution to journalArticle

Lipocalins
rosiglitazone
Peroxisome Proliferator-Activated Receptors
Energy Metabolism
Modulators
4 Citations (Scopus)

Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle

Olthoff, J. T., Lindsay, A., Abo-Zahrah, R., Baltgalvis, K. A., Patrinostro, X., Belanto, J. J., Yu, D. Y., Perrin, B. J., Garry, D. J., Rodney, G. G., Lowe, D. A. & Ervasti, J. M., Dec 1 2018, In : Nature communications. 9, 1, 5104.

Research output: Contribution to journalArticle

Open Access
Peroxiredoxins
Dystrophin
eccentrics
muscles
contraction