Research Output 1970 2020

24 Citations (Scopus)

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism

Ong, K. T., Mashek, M. T., Davidson, N. O. & Mashek, D. G., May 2014, In : Journal of Lipid Research. 55, 5, p. 808-815 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Lipase
Liver
Carrier Proteins
Fatty Acids
28 Citations (Scopus)

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

Ong, K. T., Mashek, M. T., Bu, S. Y. & Mashek, D. G., Jan 1 2013, In : FASEB Journal. 27, 1, p. 313-321 9 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Lipase
Liver
Triglycerides
Glucose
8 Citations (Scopus)

GβL regulates TNFα-induced NF-k{cyrillic}B signaling by directly inhibiting the activation of Ik{cyrillic}B kinase

Kim, Y. L., Kim, J. E., Shin, K. J., Lee, S., Ahn, C., Chung, J., Kim, D. H., Seong, J. Y. & Hwang, J. I., Nov 1 2008, In : Cellular Signalling. 20, 11, p. 2127-2133 7 p.

Research output: Contribution to journalArticle

Leucine Zippers
Small Interfering RNA
Transcriptional Activation
Phosphotransferases
Down-Regulation
137 Citations (Scopus)

Guanylyl cyclase structure, function and regulation

Potter, L. R., Dec 1 2011, In : Cellular Signalling. 23, 12, p. 1921-1926 6 p.

Research output: Contribution to journalReview article

Guanylate Cyclase
Cyclic GMP
Guanylate Cyclase-Activating Proteins
Nitric Oxide
Light Signal Transduction
21 Citations (Scopus)

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain

Robinson, J. W. & Potter, L. R., Sep 4 2012, In : Science signaling. 5, 240, ra65.

Research output: Contribution to journalArticle

Dimers
Natriuretic Peptides
Guanosine Triphosphate
Catalytic Domain
Adenosine Triphosphate
3 Citations (Scopus)

Guanylyl cyclases

Potter, L. R., Dec 1 2010, Handbook of Cell Signaling, 2/e. Elsevier Inc., Vol. 2. p. 1399-1407 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Guanylate Cyclase
Natriuretic Peptides
Amino Acids
Endothelium-Dependent Relaxing Factors
Peptide Receptors
165 Citations (Scopus)

Guanylyl Cyclase-linked Natriuretic Peptide Receptors: Structure and Regulation

Potter, L. R. & Hunter, T., Mar 2 2001, In : Journal of Biological Chemistry. 276, 9, p. 6057-6060 4 p.

Research output: Contribution to journalShort survey

Atrial Natriuretic Factor Receptors
Natriuretic Peptides
Peptide Receptors
Guanylate Cyclase
Glycosylation
18 Citations (Scopus)
Guanylate Cyclase
Cardiac Myocytes
Atrial Natriuretic Factor
Membranes
atrial natriuretic factor receptor A
97 Citations (Scopus)

Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

Mi, N. L., Sang, H. H., Kim, J., Koh, A., Chang, S. L., Jung, H. K., Jeon, H., Kim, D. H., Suh, P. G. & Sung, H. R., Jul 1 2009, In : Molecular and cellular biology. 29, 14, p. 3991-4001 11 p.

Research output: Contribution to journalArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Sirolimus
Glucose
AMP-Activated Protein Kinases
Glyceraldehyde 3-Phosphate
54 Citations (Scopus)

Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide dependent enzyme from Saccharomyces cerevisiae

Roon, R. J., Even, H. L. & Larimore, F., Dec 1 1974, In : Journal of bacteriology. 118, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Glutamate Synthase
Glutamate Dehydrogenase
Glutamine
NAD
Glutamate Synthase (NADH)
30 Citations (Scopus)

Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemia

McFalls, E. O., Murad, B., Liow, J. S., Gannon, M. C., Haspel, H. C., Lange, A. J., Marx, D., Sikora, J. & Ward, H. B., Jun 29 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 282, 1 51-1

Research output: Contribution to journalArticle

Glycogen
Swine
Ischemia
Glucose
Hexokinase
3 Citations (Scopus)

Generating GO slim using relational database management systems to support proteomics analysis

Onsongo, G., Xie, H., Griffin, T. J. & Carlis, J., Sep 22 2008, Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems, CBMS 2008. p. 215-217 3 p. 4561989. (Proceedings - IEEE Symposium on Computer-Based Medical Systems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Database Management Systems
Gene Ontology
Proteomics
Ontology
Genes
103 Citations (Scopus)

Gel-free mass spectrometry-based high throughput proteomics: Tools for studying biological response of proteins and proteomes

Roe, M. R. & Griffin, T. J., Sep 1 2006, In : Proteomics. 6, 17, p. 4678-4687 10 p.

Research output: Contribution to journalReview article

Proteome
Proteomics
Mass spectrometry
Mass Spectrometry
Gels
18 Citations (Scopus)

Galbanic acid decreases androgen receptor abundance and signaling and induces G 1 arrest in prostate cancer cells

Zhang, Y., KIM, KWAN. HYUN., Zhang, W., Guo, Y., Kim, S. H. & Lü, J., Jan 11 2012, In : International Journal of Cancer. 130, 1, p. 200-212 13 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
galbanic acid
Ferula
Growth
3 Citations (Scopus)

GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

Grunwald, D. S., Otto, N. M., Park, J-M., Song, D. & Kim, D-H., Jan 1 2019, In : Autophagy.

Research output: Contribution to journalArticle

Autophagy
Microtubule-Associated Proteins
GABA-A Receptors
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
63 Citations (Scopus)

Functional substitution by TAT-utrophin in dystrophin-deficient mice

Sonnemann, K. J., Heun-Johnson, H., Turner, A. J., Baltgalvis, K. A., Lowe, D. A. & Ervasti, J. M., May 1 2009, In : PLoS medicine. 6, 5, e1000083.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Inbred mdx Mouse
Phenotype
Proteins
Signal Transducing Adaptor Proteins
Glucokinase
Zucker Rats
Glucose-6-Phosphatase
Sorbitol
28 Citations (Scopus)

Fibroblast Growth Factor Receptor 1 Activation in Mammary Tumor Cells Promotes Macrophage Recruitment in a CX3CL1-Dependent Manner

Reed, J. R., Stone, M. D., Beadnell, T. C., Ryu, Y., Griffin, T. J. & Schwertfeger, K. L., Sep 24 2012, In : PloS one. 7, 9, e45877.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 1
Macrophages
mammary neoplasms (animal)
Tumors
macrophages
14 Citations (Scopus)

Evidence for a common component in kinetically distinct transport systems of Saccharomyces cerevisiae

Roon, R. J., Meyer, G. M. & Larimore, F. S., Jan 1 1977, In : MGG Molecular & General Genetics. 158, 2, p. 185-191 7 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Amino Acid Transport Systems
Ionophores
Ammonia
Adenosine Triphosphatases
Open Access
Papanicolaou Test
Microbiota
Fixatives
Protein Databases
Proteins
12 Citations (Scopus)
Mouth Neoplasms
Biomarkers
Exudates and Transudates
Tumor Biomarkers
Proteomics
57 Citations (Scopus)
Yeast
Chromatin
Mass spectrometry
Peptides
Electrophoresis
4 Citations (Scopus)

Essential nucleotide- and protein-dependent functions of Actb/β-actin

Patrinostro, X., Roy, P., Lindsay, A., Chamberlain, C. M., Sundby, L. J., Starker, C., Voytas, D. F., Ervasti, J. M. & Perrin, B. J., Jul 31 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 31, p. 7973-7978 6 p.

Research output: Contribution to journalArticle

Open Access
Actins
Nucleotides
Stereocilia
Proteins
High-Frequency Hearing Loss

Erratum: Statement of retraction (Diabetes (2012) 61 (3114-3125))

Zhang, W., Zhang, X., Wang, H., Guo, X., Li, H., Wang, Y., Xu, X., Tan, L., Mashek, M. T., Zhang, C., Chen, Y., Mashek, D. G., Foretz, M., Zhu, C., Zhou, H., Liu, X., Viollet, B., Wu, C. & Huo, Y., Mar 1 2013, In : Diabetes. 62, 3, 1 p.

Research output: Contribution to journalComment/debate

287 Citations (Scopus)

Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase 2

Kim, Y-M., Jang, J. W., Lee, O. H., Yeon, J., Choi, E. Y., Kim, K. W., Lee, S. T. & Kwon, Y. G., Oct 1 2000, In : Cancer Research. 60, 19, p. 5410-5413 4 p.

Research output: Contribution to journalArticle

Endostatins
Matrix Metalloproteinase 2
Matrix Metalloproteinases
Metalloproteases
Neoplasms

Emerging non-invasively collected genomic and proteomic biomarkers for the early diagnosis of oral squamous cell carcinoma (OSCC)

Kooren, J. A., Rhodus, N. L. & Griffin, T. J., Dec 1 2012, Squamous Cell Carcinoma. Nova Science Publishers, Inc., p. 197-210 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biomarkers
Proteomics
Mouth Neoplasms
Early Diagnosis
Squamous Cell Carcinoma
21 Citations (Scopus)

Effects of internal cleavages and mutations in the C-terminal region of NIa protease of turnip mosaic potyvirus on the catalytic activity

Kim, D. H., Hwang, D. C., Kang, B. H., Lew, J., Han, J., Song, B. D. & Choi, K. Y., Dec 15 1996, In : Virology. 226, 2, p. 183-190 8 p.

Research output: Contribution to journalArticle

Potyvirus
Intranuclear Inclusion Bodies
Brassica napus
Nuclear Proteins
Peptide Hydrolases
48 Citations (Scopus)

Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism

Schwinkendorf, D. R., Tsatsos, N. G., Gosnell, B. A. & Mashek, D., Mar 1 2011, In : International Journal of Obesity. 35, 3, p. 336-344 9 p.

Research output: Contribution to journalArticle

Neuropeptides
Energy Metabolism
Fatty Acids
Oleic Acid
Eating
5 Citations (Scopus)

Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation

Chow, L. S., Mashek, D. G., Wang, Q., Shepherd, S. O., Goodpaster, B. H. & Dubé, J. J., Jul 2017, In : Journal of applied physiology. 123, 1, p. 71-78 8 p.

Research output: Contribution to journalArticle

Open Access
Hyperinsulinism
Nonesterified Fatty Acids
Lipids
Glucose Clamp Technique
Insulin Resistance

Editorial introductions

Abumrad, N., Lange, A., Pichard, C., Meguid, M., D'Alessio, D. & Tappy, L., Jul 1 2006, In : Current opinion in clinical nutrition and metabolic care. 9, 4, p. VII-IX

Research output: Contribution to journalEditorial

302 Citations (Scopus)

Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle

Ohlendieck, K., Ervasti, J. M., Matsumura, K., Kahl, S. D., Leveille, C. J. & Campbell, K. P., Sep 1991, In : Neuron. 7, 3, p. 499-508 10 p.

Research output: Contribution to journalArticle

Utrophin
Neuromuscular Junction
Skeletal Muscle
Dystrophin
Inbred mdx Mouse
1 Citation (Scopus)

Dystrophinopathy-associated dysfunction of Krebs cycle metabolism

Lindsay, A., Chamberlain, C. M., Witthuhn, B. A., Lowe, D. A. & Ervasti, J. M., Jan 1 2019, In : Human molecular genetics. 28, 6, p. 942-951 10 p.

Research output: Contribution to journalArticle

Citric Acid Cycle
Succinic Acid
Dystrophin
Muscles
Inbred mdx Mouse
108 Citations (Scopus)

Dystrophin is a microtubule-associated protein

Prins, K. W., Humston, J. L., Mehta, A., Tate, V., Ralston, E. & Ervasti, J. M., Aug 10 2009, In : Journal of Cell Biology. 186, 3, p. 363-369 7 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubule-Associated Proteins
Microtubules
Tubulin
Costameres
6 Citations (Scopus)

Dystrophin As a Molecular Shock Absorber

Le, S., Yu, M., Hovan, L., Zhao, Z., Ervasti, J. & Yan, J., Dec 26 2018, In : ACS nano. 12, 12, p. 12140-12148 9 p.

Research output: Contribution to journalArticle

shock absorbers
Shock absorbers
Dystrophin
Muscle
muscular function
36 Citations (Scopus)

Dystrophin and utrophin have distinct effects on the structural dynamics of actin

Prochniewicz, E., Henderson, D., Ervasti, J. M. & Thomas, D. D., May 12 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 19, p. 7822-7827 6 p.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Actins
Anisotropy
Muscular Dystrophies
4 Citations (Scopus)

Dynamic range compression: A solution for proteomic biomarker discovery?

Griffin, T. J. & Bandhakavi, S., Sep 1 2011, In : Bioanalysis. 3, 18, p. 2053-2056 4 p.

Research output: Contribution to journalReview article

Body fluids
Body Fluids
Biomarkers
Post Translational Protein Processing
Proteomics
Open Access
Adiposity
Insulin Resistance
Young Adult
Population
Body Mass Index
41 Citations (Scopus)

Dual role of phosphofructokinase-2/fructose bisphosphatase-2 in regulating the compartmentation and expression of glucokinase in hepatocytes

Payne, V. A., Arden, C., Wu, C., Lange, A. J. & Agius, L., Jul 1 2005, In : Diabetes. 54, 7, p. 1949-1957 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Fructose-Bisphosphatase
Glucokinase
Hepatocytes
Fructose
8 Citations (Scopus)

DRAGging amino Acid-mTORC1 signaling by SH3BP4

Kim, Y. M. & Kim, D. H., Jan 1 2013, In : Molecules and cells. 35, 1, p. 1-6 6 p.

Research output: Contribution to journalReview article

GTP Phosphohydrolases
Carrier Proteins
Amino Acids
Intercellular Signaling Peptides and Proteins
Tuberous Sclerosis
2 Citations (Scopus)
Peroxiredoxin III
Adipocytes
Down-Regulation
Insulin
Oxidation
35 Citations (Scopus)
Natriuretic Peptides
Peptide Receptors
Guanylate Cyclase
Down-Regulation
Atrial Natriuretic Factor
48 Citations (Scopus)
Guanylate Cyclase-Coupled Receptors
Guanylate Cyclase
Ligands
Guanylate Cyclase-Activating Proteins
Atrial Natriuretic Factor Receptors

Distinct mechanical properties in homologous spectrin-like repeats of utrophin

Rajaganapathy, S., McCourt, J. L., Ghosal, S., Lindsay, A., McCourt, P. M., Lowe, D. A., Ervasti, J. M. & Salapaka, M. V., Dec 1 2019, In : Scientific reports. 9, 1, 5210.

Research output: Contribution to journalArticle

Open Access
Utrophin
Spectrin
Dystrophin
Dystroglycans
Connectin
36 Citations (Scopus)

Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes

Ro, S. H., Jung, C. H., Hahn, W. S., Xu, X., Kim, Y. M., Yun, Y. S., Park, J. M., Kim, K. H., Seo, M., Ha, T. Y., Arriaga, E. A., Bernlohr, D. A. & Kim, D. H., Dec 1 2013, In : Autophagy. 9, 12, p. 2103-2114 12 p.

Research output: Contribution to journalArticle

Autophagy
Lipid Metabolism
Adipocytes
Adipogenesis
Glucose
2 Citations (Scopus)

Distinct cancer-promoting stromal gene expression depending on lung function

Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S., Higgins, L. A., Markowski, T., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B., Wendt, C. H. & Larsson, O., Aug 1 2019, In : American journal of respiratory and critical care medicine. 200, 3, p. 348-358 11 p.

Research output: Contribution to journalArticle

Gene Expression
Lung
Lung Neoplasms
Neoplasms
Sirolimus
13 Citations (Scopus)

Disseminating metaproteomic informatics capabilities and knowledge using the galaxy-P framework

Blank, C., Easterly, C., Gruening, B., Johnson, J., Kolmeder, C. A., Kumar, P., May, D., Mehta, S., Mesuere, B., Brown, Z., Elias, J. E., Hervey, W. J., McGowan, T., Muth, T., Nunn, B. L., Rudney, J., Tanca, A., Griffin, T. J. & Jagtap, P. D., Mar 1 2018, In : Proteomes. 6, 1, 7.

Research output: Contribution to journalArticle

Open Access
Galaxies
Informatics
Workflow
Software
Microbiota
4 Citations (Scopus)

Disease-proportional proteasomal degradation of missense dystrophins

Talsness, D. M., Belanto, J. J. & Ervasti, J. M., Oct 6 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 40, p. 12414-12419 6 p.

Research output: Contribution to journalArticle

Dystrophin
Mutation
Frameshift Mutation
Missense Mutation
Phenotype
45 Citations (Scopus)
Dystrophin
Missense Mutation
Thermodynamics
Actins
Duchenne Muscular Dystrophy
75 Citations (Scopus)
Natriuretic Peptides
Peptide Receptors
Guanylate Cyclase
Atrial Natriuretic Factor
C-Type Natriuretic Peptide