Research Output

γ-Actin is required for cytoskeletal maintenance but not development

Belyantseva, I. A., Perrin, B. J., Sonnemann, K. J., Zhu, M., Stepanyan, R., McGee, J., Frolenkov, G. I., Walsh, E. J., Friderici, K. H., Friedman, T. B. & Ervasti, J. M., Jun 16 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 24, p. 9703-9708 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

β-cell dysfunction due to increased ER stress in a stem cell model of wolfram syndrome

Shang, L., Hua, H., Foo, K., Martinez, H., Watanabe, K., Zimmer, M., Kahler, D. J., Freeby, M., Chung, W., LeDuc, C., Goland, R., Leibel, R. L. & Egli, D., Mar 1 2014, In : Diabetes. 63, 3, p. 923-933 11 p.

Research output: Contribution to journalArticle

65 Scopus citations

β-Actin specifically controls cell growth, migration, and the G-actin pool

Bunnell, T. M., Burbach, B. J., Shimizu, Y. & Ervasti, J. M., Nov 1 2011, In : Molecular biology of the cell. 22, 21, p. 4047-4058 12 p.

Research output: Contribution to journalArticle

118 Scopus citations

β-actin and fascin-2 cooperate to maintain stereocilia length

Perrin, B. J., Strandjord, D. M., Narayanan, P., Henderson, D. M., Johnson, K. R. & Ervasti, J. M., May 13 2013, In : Journal of Neuroscience. 33, 19, p. 8114-8121 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Xanthine oxidase is hyper-active in Duchenne muscular dystrophy

Lindsay, A., McCourt, P. M., Karachunski, P., Lowe, D. A. & Ervasti, J. M., Dec 2018, In : Free Radical Biology and Medicine. 129, p. 364-371 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
48 Scopus citations

Vascular endothelial growth factor up-regulates expression of receptor activator of NF-κB (RANK) in endothelial cells. Concomitant increase of angiogenic responses to rank ligand

Min, J. K., Kim, Y. M., Kim, Y. M., Kim, E. C., Gho, Y. S., Kang, I. J., Lee, S. Y., Kong, Y. Y. & Kwon, Y. G., Oct 10 2003, In : Journal of Biological Chemistry. 278, 41, p. 39548-39557 10 p.

Research output: Contribution to journalArticle

87 Scopus citations

Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins

Nelson, D. M., Lindsay, A., Judge, L. M., Duan, D., Chamberlain, J. S., Lowe, D. A. & Ervasti, J. M., Jun 15 2018, In : Human molecular genetics. 27, 12, p. 2090-2100 11 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Variable cytoplasmic actin expression impacts the sensitivity of different dystrophin-deficient mdx skeletal muscles to eccentric contraction

Lindsay, A., Southern, W. M., McCourt, P. M., Larson, A. A., Hodges, J. S., Lowe, D. A. & Ervasti, J. M., Jul 2019, In : FEBS Journal. 286, 13, p. 2562-2576 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Utilization of the resolved l-isomer of 2-amino-6-phosphonohexanoic acid (l-AP6) as a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons

Schulte, M. K., Roon, R. J., Chalmers, D. J., Sunter, D. C. & Koerner, J. F., Jun 27 1994, In : Brain Research. 649, 1-2, p. 203-207 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Utilization of D asparagine by Saccharomyces cerevisiae

Dunlop, P. C., Roon, R. J. & Even, H. L., Dec 1 1976, In : Journal of Bacteriology. 125, 3, p. 999-1004 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Using Representational Difference Analysis to detect changes in transcript expression of Aiptasia genes after laboratory exposure to lindane

Morgan, M. B., Parker, C. C., Robinson, J. W. & Pierce, E. M., Apr 1 2012, In : Aquatic Toxicology. 110-111, p. 66-73 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry to detect monoclonal immunoglobulin light chains in serum and urine

Barnidge, D. R., Krick, T. P., Griffin, T. J. & Murray, D. L., Nov 15 2015, In : Rapid Communications in Mass Spectrometry. 29, 21, p. 2057-2060 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Update on the moFF Algorithm for Label-Free Quantitative Proteomics

Argentini, A., Staes, A., Grüning, B., Mehta, S., Easterly, C., Griffin, T. J., Jagtap, P., Impens, F. & Martens, L., Feb 1 2019, In : Journal of Proteome Research. 18, 2, p. 728-731 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Unconventional secretion of adipocyte fatty acid binding protein 4 is mediated by autophagic proteins in a sirtuin-1-dependent manner

Josephrajan, A., Hertzel, A. V., Bohm, E. K., McBurney, M. W., Imai, S. I., Mashek, D. G., Kim, D. H. & Bernlohr, D. A., Sep 1 2019, In : Diabetes. 68, 9, p. 1767-1777 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

Jung, C. H., Jun, C. B., Ro, S. H., Kim, Y. M., Otto, N. M., Cao, J., Kundu, M. & Kim, D. H., Apr 1 2009, In : Molecular biology of the cell. 20, 7, p. 1992-2003 12 p.

Research output: Contribution to journalArticle

1112 Scopus citations

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

Park, J. M., Seo, M., Jung, C. H., Grunwald, D., Stone, M., Otto, N. M., Toso, E., Ahn, Y., Kyba, M., Griffin, T. J., Higgins, L. A. & Kim, D. H., Apr 3 2018, In : Autophagy. 14, 4, p. 584-597 14 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Tryptophan catabolism in acute exacerbations of chronic obstructive pulmonary disease

Gulcev, M., Reilly, C., Griffin, T. J., Broeckling, C. D., Sandri, B. J., Witthuhn, B. A., Hodgson, S. W., Woodruff, P. G. & Wendt, C. H., Sep 29 2016, In : International Journal of COPD. 11, 1, p. 2435-2446 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Transverse tubule calcium regulation in malignant hyperthermia

Ervasti, J. M., Mickelson, J. R. & Louis, C. F., Mar 1989, In : Archives of Biochemistry and Biophysics. 269, 2, p. 497-506 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Transport and metabolism of N-δ-chloroacetyl-L-ornithine by Saccharomyces cerevisiae

Larimore, F. S. & Roon, R. J., Jan 1 1979, In : Federation Proceedings. 38, 3 I, p. No.86

Research output: Contribution to journalArticle

Transport and metabolism of N-δ-chloroacetyl-l-ornithine by Saccharomyces cerevisiae

Larimore, F. S., Kuisk, I., Korkowski, P. M. & Roon, R. J., Jan 1 1980, In : Archives of Biochemistry and Biophysics. 204, 1, p. 234-240 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Transport and metabolic effects of α-aminoisobutyric acid in saccharomyces cerevisiae

Kim, K. W. & Roon, R. J., Nov 24 1982, In : BBA - General Subjects. 719, 2, p. 356-362 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Transport and metabolic effect of α-aminoisobutyric acid in Saccharomyces cerevisiae

Kim, K. W. & Roon, R. J., Jan 1 1982, In : Federation Proceedings. 41, 4, p. No. 5239

Research output: Contribution to journalArticle

Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity

Foo, K. S., Skowronski, A. A., Baum, D., Firdessa-Fite, R., Thams, S., Shang, L., Creusot, R. J., LeDuc, C. A., Egli, D. & Leibel, R. L., Dec 1 2019, In : Scientific reports. 9, 1, 4965.

Research output: Contribution to journalArticle

Open Access

Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice

Baltgalvis, K. A., Jaeger, M. A., Fitzsimons, D. P., Thayer, S. A., Lowe, D. A. & Ervasti, J. M., Oct 13 2011, In : Skeletal Muscle. 1, 1, 32.

Research output: Contribution to journalArticle

17 Scopus citations

Trans fats: foods, facts, and biology.

Young, S. & Mashek, D., Oct 2008, In : Minnesota medicine. 91, 10, p. 41-44 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
22 Scopus citations

Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure

Shepherd, S. O., Strauss, J. A., Wang, Q., Dube, J. J., Goodpaster, B., Mashek, D. G. & Chow, L. S., Aug 15 2017, In : Journal of Physiology. 595, 16, p. 5587-5601 15 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
42 Scopus citations

Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells

Mamedova, L. K., Yuan, K., Laudick, A. N., Fleming, S. D., Mashek, D. G. & Bradford, B. J., Aug 1 2013, In : Journal of Nutritional Biochemistry. 24, 8, p. 1499-1507 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

TNF-α drives matrix metalloproteinase-9 in squamous oral carcinogenesis

Hohberger, L., Wuertz, B. R. K., Xie, H., Griffin, T. & Ondrey, F., Aug 1 2008, In : Laryngoscope. 118, 8, p. 1395-1399 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Three-dimensional peptide fractionation for highly sensitive nanoscale LC-based shotgun proteomic analysis of complex protein mixtures

Bandhakavi, S., Markowski, T. W., Xie, H. & Griffin, T. J., Nov 10 2011, Nanoproteomics: Methods and Protocols. Toms, S. & Weil, R. (eds.). p. 47-56 10 p. (Methods in Molecular Biology; vol. 790).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Thio-NADP Is Not an Antagonist of NAADP

Dickey, D. M., Aarhus, R., Walseth, T. F. & Lee, H. C., Jan 1 1998, In : Cell biochemistry and biophysics. 28, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

The ZZ domain of dystrophin in DMD: Making sense of missense mutations

Vulin, A., Wein, N., Strandjord, D. M., Johnson, E. K., Findlay, A. R., Maiti, B., Howard, M. T., Kaminoh, Y. J., Taylor, L. E., Simmons, T. R., Ray, W. C., Montanaro, F., Ervasti, J. M. & Flanigan, K. M., Feb 1 2014, In : Human mutation. 35, 2, p. 257-264 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

The Underpinnings of PNPLA3-Mediated Fatty Liver Emerge

Shang, L. & Mashek, D. G., Jan 1 2020, In : Hepatology. 71, 1, p. 375-377 3 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14

Park, J. M., Jung, C. H., Seo, M., Otto, N. M., Grunwald, D., Kim, K. H., Moriarity, B., Kim, Y. M., Starker, C., Nho, R. S., Voytas, D. & Kim, D. H., Apr 5 2016, In : Autophagy. 12, 3, p. 547-564 18 p.

Research output: Contribution to journalArticle

83 Scopus citations

The Sixth Annual Translational Stem Cell Research Conference of the New York Stem Cell Foundation

Marshall, C., Hua, H., Shang, L., Ding, B. S., Zito, G., de Peppo, G. M., Wang, G. K., Douvaras, P., Sproul, A. A., Paull, D., Fossati, V., Nestor, M. W., Mckeon, D., Smith, K. A. & Solomon, S. L., May 2012, In : Annals of the New York Academy of Sciences. 1255, 1, p. 16-29 14 p.

Research output: Contribution to journalArticle

The role of the proteasome in AML

Csizmar, C. M., Kim, D. H. & Sachs, Z., Dec 2 2016, In : Blood cancer journal. 6, 12, p. e503

Research output: Contribution to journalReview article

18 Scopus citations

The role of lipid droplets in metabolic disease in rodents and humans

Greenberg, A. S., Coleman, R. A., Kraemer, F. B., McManaman, J. L., Obin, M. S., Puri, V., Yan, Q. W., Miyoshi, H. & Mashek, D. G., Jun 1 2011, In : Journal of Clinical Investigation. 121, 6, p. 2102-2110 9 p.

Research output: Contribution to journalReview article

338 Scopus citations
3 Scopus citations

The proteome of human saliva

Griffin, T. J., Aug 12 2013, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring III. 87230A. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 8723).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The metabolism of cancer cells: Moonlighting proteins and growth control

Abumrad, N. A. & Lange, A. J., Jul 1 2006, In : Current opinion in clinical nutrition and metabolic care. 9, 4, p. 337-338 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B

Robinson, J. W., Lou, X. & Potter, L. R., Sep 1 2011, In : British Journal of Pharmacology. 164, 2 B, p. 499-506 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

The human saliva proteome: Overview and emerging methods for characterization

Griffin, T. J., Jan 1 2015, Advances in Global Health Through Sensing Technologies 2015. Southern, S. O., Gartner, C., Stallings, J. D. & Rodriguez-Chavez, I. R. (eds.). SPIE, Vol. 9490. 949003

Research output: Chapter in Book/Report/Conference proceedingConference contribution

The galaxy platform for reproducible affinity proteomic mass spectrometry data analysis

Stewart, P. A., Kuenzi, B. M., Mehta, S., Kumar, P., Johnson, J. E., Jagtap, P., Griffin, T. J. & Haura, E. B., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 249-261 13 p. (Methods in Molecular Biology; vol. 1977).

Research output: Chapter in Book/Report/Conference proceedingChapter

The experimental use of cooperative learning groups in a biochemistry laboratory course for first-year medical students

Roon, R. J., Van Pilsum, J. F., Harris, I., Rosenberg, P., Johnson, R., Liaw, C. & Rosenthal, L., Jan 1983, In : Biochemical Education. 11, 1, p. 12-15 4 p.

Research output: Contribution to journalArticle

The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni

Nam, G. H., Cha, S. S., Yun, Y. S., Yun Hee, O. H., Hong, B. H., Lee, H. S. & Choi, K. Y., Oct 15 2003, In : Biochemical Journal. 375, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

CGTP Collaborators, Dec 1 2019, In : British Journal of Pharmacology. 176, S1, p. S297-S396

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

The carboxy-terminal third of dystrophin enhances actin binding activity

Henderson, D. M., Lin, A. Y., Thomas, D. D. & Ervasti, J. M., Feb 24 2012, In : Journal of Molecular Biology. 416, 3, p. 414-424 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
38 Scopus citations