Research Output 1973 2019

15 Citations (Scopus)

Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma

Hong, S. M., Park, C. W., Cha, H. J., Kwon, J. H., Yun, Y. S., Lee, N. G., Kim, D. G., Nam, H. G. & Choi, K. Y., Feb 1 2013, In : Clinical and Experimental Metastasis. 30, 2, p. 177-187 11 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Sirolimus
Down-Regulation
Neoplasms
Epithelium
114 Citations (Scopus)

Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet

Mashek, D. G., Li, L. O. & Coleman, R. A., Sep 22 2006, In : Journal of Lipid Research. 47, 9, p. 2004-2010 7 p.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Acyl Coenzyme A
Tissue Distribution
Nutrition
Rats
17 Citations (Scopus)

Reactions of asparaginase II of Saccharomyces cerevisiae. A mechanistic analysis of hydrolysis and hydroxylaminolysis

Dunlop, P. C., Meyer, G. M. & Roon, R. J., Jan 1 1980, In : Journal of Biological Chemistry. 255, 4, p. 1542-1546 5 p.

Research output: Contribution to journalArticle

Hydroxylamines
pH
Asparaginase
Substrate Specificity
Yeast
129 Citations (Scopus)

Reducing dry period length to simplify feeding transition cows: Milk production, energy balance, and metabolic profiles

Rastani, R. R., Grummer, R. R., Bertics, S. J., Gümen, A., Wiltbank, M. C., Mashek, D. & Schwab, M. C., Jan 1 2005, In : Journal of Dairy Science. 88, 3, p. 1004-1014 11 p.

Research output: Contribution to journalArticle

dry period (lactation)
Metabolome
energy balance
Postpartum Period
milk production
42 Citations (Scopus)

Reduction of hepatic glucose production as a therapeutic target in the treatment of diabetes

Wu, C., Okar, D. A., Kang, J. & Lange, A. J., Mar 1 2005, In : Current Drug Targets: Immune, Endocrine and Metabolic Disorders. 5, 1, p. 51-59 9 p.

Research output: Contribution to journalReview article

Glucose
Liver
Therapeutics
Enzymes
Glycogenolysis
81 Citations (Scopus)

Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases

Potter, L. R., Jan 1 2011, In : Pharmacology and Therapeutics. 130, 1, p. 71-82 12 p.

Research output: Contribution to journalReview article

Peptide Receptors
Guanylate Cyclase
C-Type Natriuretic Peptide
Therapeutics
Dwarfism
363 Citations (Scopus)

Regulation of glucose production by the liver

Nordlie, R. C., Foster, J. D. & Lange, A. J., Aug 20 1999, In : Annual Review of Nutrition. 19, p. 379-406 28 p.

Research output: Contribution to journalReview article

Glucose
Liver
Glucokinase
Glucose-6-Phosphatase
Glycogenolysis
21 Citations (Scopus)

Regulation of intraocular pressure by soluble and membrane guanylate cyclases and their role in glaucoma

Buys, E. S., Potter, L. R., Pasquale, L. R. & Ksander, B. R., May 19 2014, In : Frontiers in Molecular Neuroscience. 7, MAY, 38.

Research output: Contribution to journalReview article

Intraocular Pressure
Glaucoma
Membranes
Optic Nerve Diseases
Natriuretic Peptides
155 Citations (Scopus)

Regulation of rat liver glucose-6-phosphatase gene expression in different nutritional and hormonal states: Gene structure and 5'-flanking sequence

Argaud, D., Zhang, Q., Pan, W., Maitra, S., Pilkis, S. J. & Lange, A. J., Jan 1 1996, In : Diabetes. 45, 11, p. 1563-1571 9 p.

Research output: Contribution to journalArticle

Glucose-6-Phosphatase
5' Flanking Region
Gene Expression
Liver
Genes

Regulation of the natriuretic peptide receptor 2 (Npr2) by phosphorylation of juxtamembrane serine and threonine residues is essential for bifurcation of sensory axons

Schmidt, H., Dickey, D. M., Dumoulin, A., Octave, M., Robinson, J. W., Kühn, R., Feil, R., Potter, L. R. & Rathjen, F. G., Nov 7 2018, In : Journal of Neuroscience. 38, 45, p. 9768-9780 13 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Peptide Receptors
Threonine
Serine
Axons
18 Citations (Scopus)
Methylamines
Glutamates
Asparaginase
Glutamate Dehydrogenase
Cell-Free System
35 Citations (Scopus)

Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase

Okar, D. A., Wu, C. & Lange, A. J., Dec 14 2004, In : Advances in Enzyme Regulation. 44, 1, p. 123-154 32 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Fructose-Bisphosphatase
Liver
Enzymes
Glycolysis
9 Citations (Scopus)

Relative importance of βcyto-and γcyto-actin in primary mouse embryonic fibroblasts

Patrinostro, X., O'Rourke, A. R., Chamberlain, C. M., Moriarity, B. S., Perrin, B. J. & Ervasti, J. M., Mar 15 2017, In : Molecular biology of the cell. 28, 6, p. 771-782 12 p.

Research output: Contribution to journalArticle

Open Access
Actins
Fibroblasts
Gene Targeting
Protein Isoforms
Serum Response Factor
41 Citations (Scopus)
Atrial Natriuretic Factor Receptors
Atrial Natriuretic Factor
Heart Failure
Kidney
Guanylate Cyclase
23 Citations (Scopus)

Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain

Cheever, T. R., Li, B. & Ervasti, J. M., Mar 5 2012, In : PloS one. 7, 3, e32970.

Research output: Contribution to journalArticle

Ablation
actin
Actins
Brain
brain
83 Citations (Scopus)

Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells

Zhou, H., Shang, L., Li, X., Zhang, X., Gao, G., Guo, C., Chen, B., Liu, Q., Gong, Y. & Shao, C., Oct 15 2009, In : Experimental Cell Research. 315, 17, p. 2953-2962 10 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
Catenins
Osteogenesis
Glycogen Synthase Kinase 3
resveratrol
109 Citations (Scopus)

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

Mashek, D. G., Bornfeldt, K. E., Coleman, R. A., Berger, J., Bernlohr, D. A., Black, P., DiRusso, C. C., Farber, S. A., Guo, W., Hashimoto, N., Khodiyar, V., Kuypers, F. A., Maltais, L. J., Nebert, D. W., Renieri, A., Schaffer, J. E., Stahl, A., Watkins, P. A., Vasiliou, V. & Yamamoto, T. T., Oct 1 2004, In : Journal of Lipid Research. 45, 10, p. 1958-1961 4 p.

Research output: Contribution to journalArticle

Coenzyme A Ligases
Acyl Coenzyme A
Terminology
Genes
Human Genome
7 Citations (Scopus)

RIPPER: A framework for MS1 only metabolomics and proteomics label-free relative quantification

Van Riper, S. K., Higgins, L., Carlis, J. V. & Griffin, T. J., Jul 1 2016, In : Bioinformatics. 32, 13, p. 2035-2037 3 p.

Research output: Contribution to journalArticle

Metabolomics
Proteomics
Mass Spectrometry
Quantification
Mass spectrometry
42 Citations (Scopus)

Roles for fructose-2,6-bisphosphate in the control of fuel metabolism: Beyond its allosteric effects on glycolytic and gluconeogenic enzymes

Wu, C., Khan, S. A., Peng, L. J. & Lange, A. J., Sep 4 2006, In : Advances in Enzyme Regulation. 46, 1, p. 72-88 17 p.

Research output: Contribution to journalArticle

Metabolism
Glucokinase
Glucose
Glucose-6-Phosphatase
Enzymes
13 Citations (Scopus)

Ryanodine receptor in different malignant hyperthermia-susceptible porcine muscles

Ervasti, J. M., Strand, M. A., Hanson, T. P., Mickelson, J. R. & Louis, C. F., Feb 20 1991, In : American Journal of Physiology - Cell Physiology. 260, 1 29-1

Research output: Contribution to journalArticle

Malignant Hyperthermia
Ryanodine Receptor Calcium Release Channel
Sarcoplasmic Reticulum
Muscle
Ryanodine
6 Citations (Scopus)

Salivary proteomics of healthy dogs: An in depth catalog

Torres, S. M. F., Furrow, E., Souza, C. P., Granick, J. L., De Jong, E. P., Griffin, T. J. & Wang, X., Jan 2018, In : PloS one. 13, 1, e0191307.

Research output: Contribution to journalArticle

Proteomics
proteomics
Dogs
Peptides
Phylogeny
30 Citations (Scopus)

Sample collection and handling considerations for peptidomic studies in whole saliva; implications for biomarker discovery

de Jong, E., Van Riper, S. K., Koopmeiners, J., Carlis, J. V. & Griffin, T. J., Nov 20 2011, In : Clinica Chimica Acta. 412, 23-24, p. 2284-2288 5 p.

Research output: Contribution to journalArticle

Biomarkers
Saliva
Freezing
Peptides
Nutritional Status
11 Citations (Scopus)

Scaling up multi-touch selection and querying: Interfaces and applications for combining mobile multi-touch input with large-scale visualization displays

Keefe, D. F., Gupta, A., Feldman, D., Carlis, J. V., Krehbiel Keefe, S. & Griffin, T. J., Oct 1 2012, In : International Journal of Human Computer Studies. 70, 10, p. 703-713 11 p.

Research output: Contribution to journalArticle

scaling
visualization
Visualization
Display devices
Biochemistry

Secretion of asparaginase II by yeast spheroplasts

Kyu Won Kim, W. K., Kamerud, J. & Roon, R. J., Jan 1 1984, In : Federation Proceedings. 43, 6

Research output: Contribution to journalArticle

Spheroplasts
Asparaginase
Yeasts
12 Citations (Scopus)

Sequence of the 5′-flanking region of the rat 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase gene: Regulation by glucocorticoids

Lange, A. J., Kummel, L., El-Maghrabi, M. R., Tauler, A., Colosia, A., Marker, A. & Pilkis, S. J., Jul 31 1989, In : Biochemical and Biophysical Research Communications. 162, 2, p. 753-760 8 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
5' Flanking Region
Gene expression
Glucocorticoids
Muscle
2 Citations (Scopus)

Sequence-specific 1H, 13C and 15N resonance assignments of the rat liver fructose-2,6-bisphosphatase domain [3]

Zangger, K., Pervushin, K., Sterk, H., Lange, A. J. & Okar, D. A., Nov 1 2003, In : Journal of Biomolecular NMR. 27, 3, p. 281-282 2 p.

Research output: Contribution to journalLetter

Nitrogen Isotopes
Phosphofructokinase-2
Carbon Isotopes
Deuterium
Liver
5 Citations (Scopus)

Serum TAG analysis differentiates between genetic and obesity-associated NAFLD

Mashek, D. G. & Greenberg, A. S., Jan 1 2014, In : Diabetes. 63, 1, p. 42-44 3 p.

Research output: Contribution to journalComment/debate

Obesity
Serum
Non-alcoholic Fatty Liver Disease
15 Citations (Scopus)

Serum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner

Shang, L., Zhou, H., Xia, Y., Wang, H., Gao, G., Chen, B., Liu, Q., Shao, C. & Gong, Y., Oct 1 2009, In : Journal of Cellular and Molecular Medicine. 13, 10, p. 4176-4184 9 p.

Research output: Contribution to journalArticle

Up-Regulation
Gene Expression
Serum
NAD
Binding Sites
48 Citations (Scopus)

SH3BP4 Is a Negative Regulator of Amino Acid-Rag GTPase-mTORC1 Signaling

Kim, Y-M., Stone, M., Hwang, T. H., Kim, Y. G., Dunlevy, J. R., Griffin, T. J. & Kim, D-H., Jun 29 2012, In : Molecular Cell. 46, 6, p. 833-846 14 p.

Research output: Contribution to journalArticle

src Homology Domains
Guanosine
Carrier Proteins
Amino Acids
Autophagy
70 Citations (Scopus)

Site mapping and characterization of O-glycan structures on α-dystroglycan isolated from rabbit skeletal muscle

Stalnaker, S. H., Hashmi, S., Lim, J. M., Aoki, K., Porterfield, M., Gutierrez-Sanchez, G., Wheeler, J., Ervasti, J. M., Bergmann, C., Tiemeyer, M. & Wells, L., Aug 6 2010, In : Journal of Biological Chemistry. 285, 32, p. 24882-24891 10 p.

Research output: Contribution to journalArticle

Dystroglycans
Tandem Mass Spectrometry
Glycosylation
Mass spectrometry
Polysaccharides
1 Citation (Scopus)

Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis

Muratore, K. A., Najt, C. P., Livezey, N. M., Marti, J., Mashek, D. & Arriaga, E., Jun 1 2018, In : Analytical and Bioanalytical Chemistry. 410, 16, p. 3629-3638 10 p.

Research output: Contribution to journalArticle

Open Access
Geriatrics
Liver
Nanoparticles
Tissue
Lipids
18 Citations (Scopus)

Skeletal muscle-specific ablation of γcyto-actin does not exacerbate the mdx phenotype

Prins, K. W., Lowe, D. A. & Ervasti, J. M., Jun 11 2008, In : PloS one. 3, 6, e2419.

Research output: Contribution to journalArticle

dystrophin
Dystrophin
Ablation
actin
Muscle
3 Citations (Scopus)
Open Access
C-Type Natriuretic Peptide
Guanylate Cyclase
Conformations
Adenosine Triphosphate
Mutation
9 Citations (Scopus)

Slx5/Slx8 Promotes Replication Stress Tolerance by Facilitating Mitotic Progression

Thu, Y. M., Van Riper, S. K., Higgins, L. A., Zhang, T., Becker, J. R., Markowski, T. W., Nguyen, H. D., Griffin, T. J. & Bielinsky, A. K., May 10 2016, In : Cell reports. 15, 6, p. 1254-1265 12 p.

Research output: Contribution to journalArticle

Minichromosome Maintenance Proteins
M Phase Cell Cycle Checkpoints
Ligases
Methyl Methanesulfonate
Protein Deficiency
3 Citations (Scopus)

Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B

Yun, Y. S., Nam, G. H., Kim, Y. G., Oh, B. H. & Choi, K. Y., Apr 1 2005, In : FEBS Journal. 272, 8, p. 1999-2011 13 p.

Research output: Contribution to journalArticle

Ketosteroids
Isomerases
Pseudomonas putida
Steroids
steroid delta-isomerase
24 Citations (Scopus)

Spatiotemporal Regulation of the Two Atrial Natriuretic Peptide Receptors in Testis

Müller, D., Mukhopadhyay, A. K., Speth, R. C., Guidone, G., Potthast, R., Potter, L. R. & Middendorff, R., Mar 1 2004, In : Endocrinology. 145, 3, p. 1392-1401 10 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor Receptors
Atrial Natriuretic Factor
Natriuretic Peptides
Seminiferous Tubules
Testis
26 Citations (Scopus)

Sphingosine-1-Phosphate Inhibits C-Type Natriuretic Peptide Activation of Guanylyl Cyclase B (GC-B/NPR-B)

Abbey-Hosch, S. E., Cody, A. N. & Potter, L. R., May 1 2004, In : Hypertension. 43, 5, p. 1103-1109 7 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Guanylate Cyclase
antineoplaston A10
Inhibitory Concentration 50
Fibroblasts
48 Citations (Scopus)

Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway

Lee, O. H., Lee, D. J., Kim, Y. M., Kim, Y. S., Kwon, H. J., Kim, K. W. & Kwon, Y. G., Feb 5 2000, In : Biochemical and Biophysical Research Communications. 268, 1, p. 47-53 7 p.

Research output: Contribution to journalArticle

Focal Adhesion Protein-Tyrosine Kinases
Phosphorylation
Endothelial cells
Type C Phospholipases
Tyrosine
10 Citations (Scopus)

Structural and functional properties of the actin gene family

Bunnell, T. M. & Ervasti, J. M., Jan 1 2011, In : Critical Reviews in Eukaryotic Gene Expression. 21, 3, p. 255-266 12 p.

Research output: Contribution to journalArticle

Actins
Protein Isoforms
Genes
Amino Acid Sequence Homology
Animal Models
6 Citations (Scopus)

Studies on the cytoplasmic protein tyrosine kinase activity of the Antarctic psychrotrophic bacterium Pseudomonas syringae

Jagtap, P. D. & Ray, M. K., Apr 15 1999, In : FEMS Microbiology Letters. 173, 2, p. 379-388 10 p.

Research output: Contribution to journalArticle

Pseudomonas syringae
Protein-Tyrosine Kinases
Bacteria
Enzymes
Peptides
55 Citations (Scopus)
Coenzyme A Ligases
Fatty Acid Transport Proteins
Acyl Coenzyme A
Protein Isoforms
Fatty Acids
38 Citations (Scopus)

Synthesis of Acyclic and Dehydroaspartic Acid Analogues of Ac-Asp-Glu-OH and Their Inhibition of Rat Brain N-Acetylated α-Linked Acidic Dipeptidase (NAALA Dipeptidase)

Subasinghe, N., Schulte, M., Chan, M. Y. M., Roon, R. J., Koerner, J. F. & Johnson, R. L., Jan 1 1990, In : Journal of Medicinal Chemistry. 33, 10, p. 2734-2744 11 p.

Research output: Contribution to journalArticle

aspartylglutamate
Acyclic Acids
aspartyl-aspartic acid
glutamyl-glutamic acid
Brain
14 Citations (Scopus)

Synthesis of Oxadiazolidinedione Derivatives as Quisqualic Acid Analogues and Their Evaluation at a Quisqualate-Sensitized Site in the Rat Hippocampus

Venkatraman, S., Roon, R. J., Schulte, M. K., Koerner, J. F. & Johnson, R. L., Nov 1 1994, In : Journal of Medicinal Chemistry. 37, 23, p. 3939-3946 8 p.

Research output: Contribution to journalArticle

Quisqualic Acid
Hippocampus
Neurons
Excitatory Amino Acids
Structure-Activity Relationship
31 Citations (Scopus)

Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses

Huo, Y., Guo, X., Li, H., Xu, H., Halim, V., Zhang, W., Wang, H., Fan, Y. Y., Ong, K. T., Woo, S. L., Chapkin, R. S., Mashek, D. G., Chen, Y., Dong, H., Lu, F., Wei, L. & Wu, C., Jun 15 2012, In : Journal of Biological Chemistry. 287, 25, p. 21492-21500 9 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Nutrition
Liver
Transgenic Mice
Insulin Resistance
18 Citations (Scopus)

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice

Call, J. A., Ervasti, J. M. & Lowe, D. A., Jul 1 2011, In : Journal of Applied Physiology. 111, 1, p. 200-205 6 p.

Research output: Contribution to journalArticle

Utrophin
Inbred mdx Mouse
Dystrophin
Knockout Mice
Food
14 Citations (Scopus)

T Cell-Expressed CD40L potentiates the bone anabolic activity of intermittent PTH treatment

Robinson, J. W., Li, J. Y., Walker, L. D., Tyagi, A. M., Reott, M. A., Yu, M., Adams, J., Weitzmann, M. N. & Pacifici, R., Apr 1 2015, In : Journal of Bone and Mineral Research. 30, 4, p. 695-705 11 p.

Research output: Contribution to journalArticle

CD40 Ligand
Stromal Cells
T-Lymphocytes
Bone and Bones
Parathyroid Hormone
129 Citations (Scopus)

The actin gene family: Function follows isoform

Perrin, B. J. & Ervasti, J. M., Oct 1 2010, In : Cytoskeleton. 67, 10, p. 630-634 5 p.

Research output: Contribution to journalArticle

Actins
Protein Isoforms
Genes
Mammals
Amino Acid Sequence
38 Citations (Scopus)
Atrial Natriuretic Factor Receptors
Phosphoprotein Phosphatases
Magnesium
Magnesium Chloride
Guanylate Cyclase
12 Citations (Scopus)

The carboxy-terminal third of dystrophin enhances actin binding activity

Henderson, D. M., Lin, A. Y., Thomas, D. D. & Ervasti, J. M., Feb 24 2012, In : Journal of Molecular Biology. 416, 3, p. 414-424 11 p.

Research output: Contribution to journalArticle

Dystrophin
Actins
Microfilament Proteins
Anisotropy
Actin Cytoskeleton
15 Citations (Scopus)

The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni

Nam, G. H., Cha, S. S., Yun, Y. S., Yun Hee, O. H., Hong, B. H., Lee, H. S. & Choi, K. Y., Oct 15 2003, In : Biochemical Journal. 375, 2, p. 297-305 9 p.

Research output: Contribution to journalArticle

Comamonas testosteroni
Ketosteroids
Isomerases
Catalytic Domain
Equilenin