Research Output 1973 2019

6 Citations (Scopus)

High frequency hearing loss and hyperactivity in DUX4 transgenic mice

Dandapat, A., Perrin, B. J., Cabelka, C., Razzoli, M., Ervasti, J. M., Bartolomucci, A., Lowe, D. A. & Kyba, M., Mar 2016, In : PloS one. 11, 3, e0151467.

Research output: Contribution to journalArticle

High-Frequency Hearing Loss
Audition
hearing
Transgenic Mice
Doxycycline
29 Citations (Scopus)

Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis

Bandhakavi, S., Xie, H., O'Callaghan, B., Sakurai, H., Kim, D. H. & Griffin, T. J., Feb 13 2008, In : PloS one. 3, 2, e1598.

Research output: Contribution to journalArticle

Oxidative stress
Sirolimus
Proteomics
proteomics
Yeast
19 Citations (Scopus)

Human B-type natriuretic peptide is not degraded by meprin A

Dickey, D. M. & Potter, L. R., Oct 1 2010, In : Biochemical Pharmacology. 80, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

meprin A
Brain Natriuretic Peptide
Rats
Neprilysin
Membranes

Human saliva proteome: An overview

Griffin, T. J., Jan 1 2014, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV. SPIE, 91120B. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 9112).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

proteome
saliva
Proteome
proteins
Proteins
8 Citations (Scopus)

Identification and characterization of the ATP-binding site in human pancreatic glucokinase

Marotta, D. E., Anand, G. R., Anderson, T. A., Miller, S. P., Okar, D. A., Levitt, D. G. & Lange, A. J., Apr 1 2005, In : Archives of Biochemistry and Biophysics. 436, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

Glucokinase
Adenosine Triphosphate
Binding Sites
Glucose
Adenosine Diphosphate Glucose
101 Citations (Scopus)
Muscle Mitochondrion
Isotope Labeling
Affinity chromatography
Mitochondria
Tandem Mass Spectrometry
22 Citations (Scopus)

Identification of New Dystroglycan Complexes in Skeletal Muscle

Johnson, E. K., Li, B., Yoon, J. H., Flanigan, K. M., Martin, P. T., Ervasti, J. & Montanaro, F., Aug 8 2013, In : PloS one. 8, 8, e73224.

Research output: Contribution to journalArticle

Dystroglycans
dystrophin
Dystrophin
Muscle
skeletal muscle
13 Citations (Scopus)

Impacts of dystrophin and utrophin domains on actin structural dynamics: Implications for therapeutic design

Lin, A. Y., Prochniewicz-Nakayama, E., Henderson, D. M., Li, B., Ervasti, J. M. & Thomas, D. D., Jun 29 2012, In : Journal of Molecular Biology. 420, 1-2, p. 87-98 12 p.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Actins
Anisotropy
Genetic Therapy
5 Citations (Scopus)

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms

O'Rourke, A. R., Lindsay, A., Tarpey, M. D., Yuen, S., McCourt, P., Nelson, D. M., Perrin, B. J., Thomas, D. D., Spangenburg, E. E., Lowe, D. A. & Ervasti, J. M., Feb 2018, In : FEBS Journal. 285, 3, p. 481-500 20 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Dynamics
Muscle Relaxation
Ablation
Muscle
Actins
4 Citations (Scopus)

Improved intensity-based label-free quantification via proximity-based intensity normalization (PIN)

Van Riper, S. K., de Jong, E., Higgins, L., Carlis, J. V. & Griffin, T. J., Mar 7 2014, In : Journal of Proteome Research. 13, 3, p. 1281-1292 12 p.

Research output: Contribution to journalArticle

Labels
Workflow
High Pressure Liquid Chromatography
Molecules
Proteins
26 Citations (Scopus)

Improved Methods for Reprogramming Human Dermal Fibroblasts Using Fluorescence Activated Cell Sorting

Kahler, D. J., Ahmad, F. S., Ritz, A., Hua, H., Moroziewicz, D. N., Sproul, A. A., Dusenberry, C. R., Shang, L., Paull, D., Zimmer, M., Weiss, K. A., Egli, D. & Noggle, S. A., Mar 29 2013, In : PloS one. 8, 3, e59867.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Fibroblasts
Stem cells
Sorting
fibroblasts
Open Access
Galaxies
Workflow
Software
Processing
Research Personnel
17 Citations (Scopus)

Independent variability of microtubule perturbations associated with dystrophinopathy

Belanto, J. J., Olthoff, J. T., Mader, T. L., Chamberlain, C. M., Nelson, D. M., McCourt, P. M., Talsness, D. M., Gundersen, G. G., Lowe, D. A. & Ervasti, J. M., Nov 15 2016, In : Human molecular genetics. 25, 22, p. 4951-4961 11 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubules
Inbred mdx Mouse
Utrophin
Tubulin
36 Citations (Scopus)

Inhibition of amino acid transport by ammonium ion in Saccharomyces cerevisiae

Roon, R. J., Larimore, F. & Levy, J. S., Dec 1 1975, In : Journal of bacteriology. 124, 1, p. 325-331 7 p.

Research output: Contribution to journalArticle

Ion Transport
Ammonium Sulfate
Ammonium Compounds
Saccharomyces cerevisiae
Cycloheximide
26 Citations (Scopus)
Phosphofructokinase-2
Glucokinase
AMP-Activated Protein Kinases
Phosphorylation
Glucose
43 Citations (Scopus)

Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response

Ralat, L. A., Guo, Q., Ren, M., Funke, T., Dickey, D. M., Potter, L. R. & Tang, W. J., Feb 11 2011, In : Journal of Biological Chemistry. 286, 6, p. 4670-4679 10 p.

Research output: Contribution to journalArticle

Insulysin
Natriuretic Peptides
Atrial Natriuretic Factor
Cyclic GMP
Cyclic Peptides
755 Citations (Scopus)

Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40

Haar, E. V., Lee, S. I., Bandhakavi, S., Griffin, T. J. & Kim, D. H., Mar 1 2007, In : Nature Cell Biology. 9, 3, p. 316-323 8 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-akt
Sirolimus
Proline
Insulin
Tuberous Sclerosis
20 Citations (Scopus)

Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins

Zhang, W., Bu, S. Y., Mashek, M. T., O-Sullivan, I. S., Sibai, Z., Khan, S. A., Ilkayeva, O., Newgard, C. B., Mashek, D. G. & Unterman, T. G., Apr 12 2016, In : Cell reports. 15, 2, p. 349-359 11 p.

Research output: Contribution to journalArticle

Lipase
Lipid Metabolism
Metabolism
Lipolysis
Lipids

Integrative effects of dystrophin loss on metabolic function of the mdx mouse

Strakova, J., Kamdar, F., Kulhanek, D., Razzoli, M., Garry, D. J., Ervasti, J. M., Bartolomucci, A. & Townsend, D. W., Dec 1 2018, In : Scientific reports. 8, 1, 13624.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Dystrophin
Duchenne Muscular Dystrophy
Skeletal Muscle
Fats
29 Citations (Scopus)

Internal deletion compromises the stability of dystrophin

Henderson, D. M., Belanto, J. J., Li, B., Heun-Johnson, H. & Ervasti, J. M., Aug 1 2011, In : Human molecular genetics. 20, 15, p. 2955-2963 9 p., ddr199.

Research output: Contribution to journalArticle

Dystrophin
Utrophin
Freezing
Proteins
Duchenne Muscular Dystrophy

Intracellular Fatty Acid Transport, Activation, and Trafficking

Mashek, D., Apr 16 2010, Adipose Tissue in Health and Disease. Wiley-VCH, p. 109-127 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Fatty Acid-Binding Proteins
Acyl Coenzyme A
Metabolic Diseases
Metabolism
Fatty Acids
85 Citations (Scopus)

Investigation of in vivo fatty acid metabolism in AFABP/aP2-/- mice

Baar, R. A., Dingfelder, C. S., Smith, L. A., Bernlohr, D. A., Wu, C., Lange, A. J. & Parks, E. J., Jan 1 2005, In : American Journal of Physiology - Endocrinology and Metabolism. 288, 1 51-1, p. E187-E193

Research output: Contribution to journalArticle

Nonesterified Fatty Acids
Fatty Acids
Serum
Liver
Glucose
23 Citations (Scopus)

Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor γ activation in mice

Guo, X., Xu, K., Zhang, J., Li, H., Zhang, W., Wang, H., Lange, A. J., Chen, Y. E., Huo, Y. & Wu, C., Jul 30 2010, In : Journal of Biological Chemistry. 285, 31, p. 23711-23720 10 p.

Research output: Contribution to journalArticle

Phosphofructokinase-2
Peroxisome Proliferator-Activated Receptors
Chemical activation
Adipocytes
Insulin
62 Citations (Scopus)

IPSC-derived β cells model diabetes due to glucokinase deficiency

Hua, H., Shang, L., Martinez, H., Freeby, M., Gallagher, M. P., Ludwig, T., Deng, L., Greenberg, E., LeDuc, C., Chung, W. K., Goland, R., Leibel, R. L. & Egli, D., Jul 1 2013, In : Journal of Clinical Investigation. 123, 7, p. 3146-3153 8 p.

Research output: Contribution to journalArticle

Glucokinase
Induced Pluripotent Stem Cells
Insulin
Phenotype
Stem Cells
15 Citations (Scopus)

Iron-sparing response of mycobacterium avium subsp. paratuberculosis is strain dependent

Janagama, H. K., Senthilkumar, Bannantine, J. P., Kugadas, A., Jagtap, P., Higgins, L., Witthuhn, B. A. & Sreevatsan, S., Oct 26 2010, In : BMC microbiology. 10, 268.

Research output: Contribution to journalArticle

Paratuberculosis
Mycobacterium avium
Iron
Metabolic Networks and Pathways
Proteomics
1 Citation (Scopus)

Isometric resistance training increases strength and alters histopathology of dystrophin-deficient mouse skeletal muscle

Lindsay, A., Larson, A. A., Verma, M., Ervasti, J. M. & Lowe, D. A., Feb 1 2019, In : Journal of applied physiology. 126, 2, p. 363-375 13 p.

Research output: Contribution to journalArticle

Open Access
Dystrophin
Resistance Training
Duchenne Muscular Dystrophy
Skeletal Muscle
Muscles
120 Citations (Scopus)

iTRAQ reagent-based quantitative proteomic analysis on a linear ion trap mass spectrometer

Griffin, T. J., Xie, H., Bandhakavi, S., Popko, J., Mohan, A., Carlis, J. V. & Higgins, L., Nov 1 2007, In : Journal of Proteome Research. 6, 11, p. 4200-4209 10 p.

Research output: Contribution to journalArticle

Mass spectrometers
Proteomics
Ions
Peptides
Software
34 Citations (Scopus)

Large-scale phosphoproteomics analysis of whole saliva reveals a distinct phosphorylation pattern

Stone, M. D., Chen, X., McGowan, T., Bandhakavi, S., Cheng, B., Rhodus, N. L. & Griffin, T. J., Apr 1 2011, In : Journal of Proteome Research. 10, 4, p. 1728-1736 9 p.

Research output: Contribution to journalArticle

Phosphorylation
Phosphoproteins
Saliva
Salivary Proteins and Peptides
Phosphotransferases
34 Citations (Scopus)

L Asparaginase of Saccharomyces cerevisiae: an extracellular enzyme

Dunlop, P. C. & Roon, R. J., Dec 1 1975, In : Journal of bacteriology. 122, 3, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

Hydroxymercuribenzoates
Species Specificity
Asparaginase
Stereoisomerism
Cell-Free System
46 Citations (Scopus)

Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-γ activation and function in lipid homeostasis and energy expenditure

Jin, D., Guo, H., Bu, S. Y., Zhang, Y., Hannaford, J., Mashek, D. & Chen, X., Feb 1 2011, In : FASEB Journal. 25, 2, p. 754-764 11 p.

Research output: Contribution to journalArticle

Lipocalins
rosiglitazone
Peroxisome Proliferator-Activated Receptors
Energy Metabolism
Modulators
116 Citations (Scopus)

Long-chain acyl-CoA synthetases and fatty acid channeling

Mashek, D., Li, L. O. & Coleman, R. A., Aug 1 2007, In : Future Lipidology. 2, 4, p. 465-476 12 p.

Research output: Contribution to journalReview article

Coenzyme A Ligases
Acyl Coenzyme A
Fatty Acid Transport Proteins
Fatty Acids
Metabolic Diseases
4 Citations (Scopus)

Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle

Olthoff, J. T., Lindsay, A., Abo-Zahrah, R., Baltgalvis, K. A., Patrinostro, X., Belanto, J. J., Yu, D. Y., Perrin, B. J., Garry, D. J., Rodney, G. G., Lowe, D. A. & Ervasti, J. M., Dec 1 2018, In : Nature communications. 9, 1, 5104.

Research output: Contribution to journalArticle

Open Access
Peroxiredoxins
Dystrophin
eccentrics
muscles
contraction
22 Citations (Scopus)

L-Quisqualic acid transport into hippocampal neurons by a cystine-sensitive carrier is required for the induction of quisqualate sensitization

Chase, L. A., Roon, R. J., Wellman, L., Beitz, A. J. & Koerner, J. F., Sep 6 2001, In : Neuroscience. 106, 2, p. 287-301 15 p.

Research output: Contribution to journalArticle

Quisqualic Acid
Cystine
Neurons
Organophosphonates
Excitatory Amino Acids
86 Citations (Scopus)

Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes

Robinson, J. W., Zhang, M., Shuhaibar, L. C., Norris, R. P., Geerts, A., Wunder, F., Eppig, J. J., Potter, L. R. & Jaffe, L. A., Jun 15 2012, In : Developmental Biology. 366, 2, p. 308-316 9 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Ovarian Follicle
Peptide Receptors
Guanylate Cyclase
Cyclic GMP
27 Citations (Scopus)

Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1

Stapleton, C. M., Mashek, D. G., Wang, S., Nagle, C. A., Cline, G. W., Thuillier, P., Leesnitzer, L. M., Li, L. O., Stimmel, J. B., Shulman, G. I. & Coleman, R. A., May 2 2011, In : PloS one. 6, 4, e18932.

Research output: Contribution to journalArticle

glycerol-3-phosphate acyltransferase
Acyltransferases
Peroxisome Proliferator-Activated Receptors
Chinese hamsters
Cricetulus
39 Citations (Scopus)

Lysophosphatidic acid inhibits C-type natriuretic peptide activation of guanylyl cyclase-B

Abbey, S. E. & Potter, L. R., Jan 1 2003, In : Endocrinology. 144, 1, p. 240-246 7 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Guanylate Cyclase
Fibroblasts
Serum
Bone Development
11 Citations (Scopus)

Maintenance of α-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B

Nam, G. H., Jang, D. S., Cha, S. S., Lee, T. H., Kim, D. H., Hong, B. H., Yun, Y. S., Oh, B. H. & Choi, K. Y., Nov 13 2001, In : Biochemistry. 40, 45, p. 13529-13537 9 p.

Research output: Contribution to journalArticle

Ketosteroids
Isomerases
Pseudomonas putida
Catalysis
Tyrosine
118 Citations (Scopus)

Mammalian triacylglycerol metabolism: Synthesis, lipolysis, and signaling

Coleman, R. A. & Mashek, D., Oct 12 2011, In : Chemical Reviews. 111, 10, p. 6359-6386 28 p.

Research output: Contribution to journalReview article

Metabolism
Protein Isoforms
Triglycerides
Fats
Nutrition
20 Citations (Scopus)

Mass spectrometry-based proteomics: Basic principles and emerging technologies and directions

Van Riper, S. K., de Jong, E., Carlis, J. V. & Griffin, T. J., Jan 1 2013, Radiation Proteomics: The Effects of Ionizing and Non-Ionizing Radiation on Cells and Tissues. Springer New York LLC, p. 1-35 35 p. (Advances in Experimental Medicine and Biology; vol. 990).

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteomics
Mass spectrometry
Mass Spectrometry
Technology
Biological radiation effects
1029 Citations (Scopus)

Membrane organization of the dystrophin-glycoprotein complex

Ervasti, J. M. & Campbell, K. P., Sep 20 1991, In : Cell. 66, 6, p. 1121-1131 11 p.

Research output: Contribution to journalArticle

Dystrophin
Dystrophin-Associated Proteins
Glycoproteins
Membranes
Oligosaccharides
36 Citations (Scopus)

Metabolic fate of long-chain unsaturated fatty acids and their effects on palmitic acid metabolism and gluconeogenesis in bovine hepatocytes

Mashek, D. G., Bertics, S. J. & Grummer, R. R., Sep 2002, In : Journal of Dairy Science. 85, 9, p. 2283-2289 7 p.

Research output: Contribution to journalArticle

long chain unsaturated fatty acids
Gluconeogenesis
gluconeogenesis
Palmitic Acid
Unsaturated Fatty Acids
33 Citations (Scopus)

Metaproteomic analysis using the Galaxy framework

Jagtap, P. D., Blakely, A., Murray, K., Stewart, S., Kooren, J., Johnson, J. E., Rhodus, N. L., Rudney, J. D. & Griffin, T. J., Oct 1 2015, In : Proteomics. 15, 20, p. 3553-3565 13 p.

Research output: Contribution to journalArticle

Galaxies
Workflow
Proteins
Blueprints
Protein Databases
1 Citation (Scopus)

MetaQuantome: An integrated, quantitative metaproteomics approach reveals connections between taxonomy and protein function in complex microbiomes

Easterly, C. W., Sajulga, R., Mehta, S., Johnson, J., Kumar, P., Hubler, S., Mesuere, B., Rudney, J., Griffin, T. J. & Jagtap, P. D., Jan 1 2019, In : Molecular and Cellular Proteomics. 18, 8, p. S82-S91

Research output: Contribution to journalArticle

Open Access
Microbiota
Taxonomies
Benchmarking
Proteins
Galaxies
80 Citations (Scopus)

Methylamine and ammonia transport in Saccharomyces cerevisiae

Roon, R. J., Even, H. L., Dunlop, P. & Larimore, F. L., Dec 1 1975, In : Journal of bacteriology. 122, 2, p. 502-503 2 p.

Research output: Contribution to journalArticle

Carbon Radioisotopes
Methylamines
Active Biological Transport
Cycloheximide
Ammonia
1 Citation (Scopus)

Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

Heden, T. D., Johnson, J. M., Ferrara, P. J., Eshima, H., Verkerke, A. R. P., Wentzler, E. J., Siripoksup, P., Narowski, T. M., Coleman, C. B., Lin, C. T., Ryan, T. E., Reidy, P. T., de Castro Brás, L. E., Karner, C. M., Burant, C. F., Alan Maschek, J., Cox, J. E., Mashek, D. G., Kardon, G., Boudina, S. & 7 others, Zeczycki, T. N., Rutter, J., Shaikh, S. R., Vance, J. E., Drummond, M. J., Darrell Neufer, P. & Funai, K., Sep 11 2019, In : Science advances. 5, 9, eaax8352.

Research output: Contribution to journalArticle

Open Access
skeletal muscle
enzymes
physical exercise
muscles
membranes
87 Citations (Scopus)

Molecular Dissection of the α-Dystroglycan- and Integrin-binding Sites within the Globular Domain of Human Laminin-10

Ido, H., Harada, K., Futaki, S., Hayashi, Y., Nishiuchi, R., Natsuka, Y., Li, S., Wada, Y., Combs, A. C., Ervasti, J. M. & Sekiguchi, K., Mar 19 2004, In : Journal of Biological Chemistry. 279, 12, p. 10946-10954 9 p.

Research output: Contribution to journalArticle

Dystroglycans
Dissection
Integrins
Binding Sites
Laminin
41 Citations (Scopus)

Mouse model of muscleblind-like 1 overexpression: Skeletal muscle effects and therapeutic promise

Chamberlain, C. M. & Ranum, L. P. W., Nov 1 2012, In : Human molecular genetics. 21, 21, p. 4645-4654 10 p., dds306.

Research output: Contribution to journalArticle

Alternative Splicing
Therapeutic Uses
Skeletal Muscle
Myotonia
Myotonic Dystrophy
5 Citations (Scopus)

Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with duchenne or becker muscular dystrophy

McCourt, J. L., Talsness, D. M., Lindsay, A., Arpke, R. W., Chatterton, P. D., Nelson, D. M., Chamberlain, C. M., Olthoff, J. T., Belanto, J. J., McCourt, P. M., Kyba, M., Lowe, D. A. & Ervasti, J. M., Feb 1 2018, In : Human molecular genetics. 27, 3, p. 451-462 12 p.

Research output: Contribution to journalArticle

Open Access
Dystrophin
Duchenne Muscular Dystrophy
Missense Mutation
Actins
Proteasome Endopeptidase Complex
87 Citations (Scopus)

MTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation

Kim, Y. M., Jung, C. H., Seo, M., Kim, E. K., Park, J. M., Bae, S. S. & Kim, D. H., Jan 22 2015, In : Molecular Cell. 57, 2, p. 207-218 12 p.

Research output: Contribution to journalArticle

Endosomes
Autophagy
Epidermal Growth Factor Receptor
Lysosomes
Autophagosomes
1148 Citations (Scopus)

MTOR regulation of autophagy

Jung, C. H., Ro, S. H., Cao, J., Otto, N. M. & Kim, D-H., Jan 1 2010, In : FEBS Letters. 584, 7, p. 1287-1295 9 p.

Research output: Contribution to journalReview article

Autophagy
Sirolimus
Cell growth
Eukaryotic Cells
Growth