Research Output 1973 2019

5 Citations (Scopus)

Dystrophin As a Molecular Shock Absorber

Le, S., Yu, M., Hovan, L., Zhao, Z., Ervasti, J. & Yan, J., Dec 26 2018, In : ACS nano. 12, 12, p. 12140-12148 9 p.

Research output: Contribution to journalArticle

shock absorbers
Shock absorbers
Dystrophin
Muscle
muscular function
106 Citations (Scopus)

Dystrophin is a microtubule-associated protein

Prins, K. W., Humston, J. L., Mehta, A., Tate, V., Ralston, E. & Ervasti, J. M., Aug 10 2009, In : Journal of Cell Biology. 186, 3, p. 363-369 7 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubule-Associated Proteins
Microtubules
Tubulin
Costameres
1 Citation (Scopus)

Dystrophinopathy-associated dysfunction of Krebs cycle metabolism

Lindsay, A., Chamberlain, C. M., Witthuhn, B. A., Lowe, D. A. & Ervasti, J. M., Jan 1 2019, In : Human molecular genetics. 28, 6, p. 942-951 10 p.

Research output: Contribution to journalArticle

Citric Acid Cycle
Succinic Acid
Dystrophin
Muscles
Inbred mdx Mouse
298 Citations (Scopus)

Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle

Ohlendieck, K., Ervasti, J. M., Matsumura, K., Kahl, S. D., Leveille, C. J. & Campbell, K. P., Jan 1 1991, In : Neuron. 7, 3, p. 499-508 10 p.

Research output: Contribution to journalArticle

Utrophin
Neuromuscular Junction
Skeletal Muscle
Dystrophin
Inbred mdx Mouse

Editorial introductions

Abumrad, N., Lange, A., Pichard, C., Meguid, M., D'Alessio, D. & Tappy, L., Jul 1 2006, In : Current opinion in clinical nutrition and metabolic care. 9, 4, p. VII-IX

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation

Chow, L. S., Mashek, D., Wang, Q., Shepherd, S. O., Goodpaster, B. H. & Dubé, J. J., Jul 1 2017, In : Journal of applied physiology. 123, 1, p. 71-78 8 p.

Research output: Contribution to journalArticle

Open Access
Hyperinsulinism
Nonesterified Fatty Acids
Lipids
Glucose Clamp Technique
Insulin Resistance
45 Citations (Scopus)

Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism

Schwinkendorf, D. R., Tsatsos, N. G., Gosnell, B. A. & Mashek, D., Mar 1 2011, In : International Journal of Obesity. 35, 3, p. 336-344 9 p.

Research output: Contribution to journalArticle

Neuropeptides
Energy Metabolism
Fatty Acids
Oleic Acid
Eating

Emerging non-invasively collected genomic and proteomic biomarkers for the early diagnosis of oral squamous cell carcinoma (OSCC)

Kooren, J. A., Rhodus, N. L. & Griffin, T. J., Dec 1 2012, Squamous Cell Carcinoma. Nova Science Publishers, Inc., p. 197-210 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Biomarkers
Proteomics
Mouth Neoplasms
Early Diagnosis
Squamous Cell Carcinoma
287 Citations (Scopus)

Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase 2

Kim, Y-M., Jang, J. W., Lee, O. H., Yeon, J., Choi, E. Y., Kim, K. W., Lee, S. T. & Kwon, Y. G., Oct 1 2000, In : Cancer Research. 60, 19, p. 5410-5413 4 p.

Research output: Contribution to journalArticle

Endostatins
Matrix Metalloproteinase 2
Matrix Metalloproteinases
Metalloproteases
Neoplasms
128 Citations (Scopus)

Engineering bone tissue substitutes from human induced pluripotent stem cells

De Peppo, G. M., Marcos-Campos, I., Kahler, D. J., Alsalman, D., Shang, L., Vunjak-Novakovic, G. & Marolt, D., May 21 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 21, p. 8680-8685 6 p.

Research output: Contribution to journalArticle

Bone Substitutes
Induced Pluripotent Stem Cells
Bone and Bones
Bioreactors
Perfusion
Dystrophin
Medical Genetics
Microtubules
Molecular Biology
Phenotype

Erratum: Statement of retraction (Diabetes (2012) 61 (3114-3125))

Zhang, W., Zhang, X., Wang, H., Guo, X., Li, H., Wang, Y., Xu, X., Tan, L., Mashek, M. T., Zhang, C., Chen, Y., Mashek, D. G., Foretz, M., Zhu, C., Zhou, H., Liu, X., Viollet, B., Wu, C. & Huo, Y., Mar 1 2013, In : Diabetes. 62, 3, 1 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)

Essential nucleotide- and protein-dependent functions of Actb/β-actin

Patrinostro, X., Roy, P., Lindsay, A., Chamberlain, C. M., Sundby, L. J., Starker, C., Voytas, D. F., Ervasti, J. M. & Perrin, B. J., Jul 31 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 31, p. 7973-7978 6 p.

Research output: Contribution to journalArticle

Open Access
Actins
Nucleotides
Stereocilia
Proteins
High-Frequency Hearing Loss
57 Citations (Scopus)
Yeast
Chromatin
Mass spectrometry
Peptides
Electrophoresis
11 Citations (Scopus)
Mouth Neoplasms
Biomarkers
Exudates and Transudates
Tumor Biomarkers
Proteomics
Open Access
Papanicolaou Test
Microbiota
Fixatives
Protein Databases
Proteins
14 Citations (Scopus)

Evidence for a common component in kinetically distinct transport systems of Saccharomyces cerevisiae

Roon, R. J., Meyer, G. M. & Larimore, F. S., Jan 1 1977, In : MGG Molecular & General Genetics. 158, 2, p. 185-191 7 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Amino Acid Transport Systems
Ionophores
Ammonia
Adenosine Triphosphatases
26 Citations (Scopus)

Expression of mammalian liver glycolytic/ gluconeogenic enzymes in Escherichia coli: Recovery of active enzyme is strain and temperature dependent

Lin, K., Kurland, I., Xu, L. Z., Lange, A. J., Pilkis, J., El-Maghrabi, M. R. & Pilkis, S. J., Jan 1 1990, In : Protein Expression and Purification. 1, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

Escherichia coli
Temperature
Liver
Enzymes
Fructose-Bisphosphatase
28 Citations (Scopus)

Fibroblast Growth Factor Receptor 1 Activation in Mammary Tumor Cells Promotes Macrophage Recruitment in a CX3CL1-Dependent Manner

Reed, J. R., Stone, M. D., Beadnell, T. C., Ryu, Y., Griffin, T. J. & Schwertfeger, K. L., Sep 24 2012, In : PloS one. 7, 9, e45877.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 1
Macrophages
mammary neoplasms (animal)
Tumors
macrophages
Signal Transducing Adaptor Proteins
Glucokinase
Zucker Rats
Glucose-6-Phosphatase
Sorbitol
63 Citations (Scopus)

Functional substitution by TAT-utrophin in dystrophin-deficient mice

Sonnemann, K. J., Heun-Johnson, H., Turner, A. J., Baltgalvis, K. A., Lowe, D. A. & Ervasti, J. M., May 1 2009, In : PLoS Medicine. 6, 5, e1000083.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Inbred mdx Mouse
Phenotype
Proteins
2 Citations (Scopus)

GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

Grunwald, D. S., Otto, N. M., Park, J-M., Song, D. & Kim, D-H., Jan 1 2019, In : Autophagy.

Research output: Contribution to journalArticle

Autophagy
Microtubule-Associated Proteins
GABA-A Receptors
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
17 Citations (Scopus)

Galbanic acid decreases androgen receptor abundance and signaling and induces G 1 arrest in prostate cancer cells

Zhang, Y., KIM, KWAN. HYUN., Zhang, W., Guo, Y., Kim, S. H. & Lü, J., Jan 11 2012, In : International Journal of Cancer. 130, 1, p. 200-212 13 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
galbanic acid
Ferula
Growth
103 Citations (Scopus)

Gel-free mass spectrometry-based high throughput proteomics: Tools for studying biological response of proteins and proteomes

Roe, M. R. & Griffin, T. J., Sep 1 2006, In : Proteomics. 6, 17, p. 4678-4687 10 p.

Research output: Contribution to journalReview article

Proteome
Proteomics
Mass spectrometry
Mass Spectrometry
Gels
3 Citations (Scopus)

Generating GO slim using relational database management systems to support proteomics analysis

Onsongo, G., Xie, H., Griffin, T. J. & Carlis, J., Sep 22 2008, Proceedings of the 21st IEEE International Symposium on Computer-Based Medical Systems, CBMS 2008. p. 215-217 3 p. 4561989. (Proceedings - IEEE Symposium on Computer-Based Medical Systems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Database Management Systems
Gene Ontology
Proteomics
Ontology
Genes
30 Citations (Scopus)

Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemia

McFalls, E. O., Murad, B., Liow, J. S., Gannon, M. C., Haspel, H. C., Lange, A. J., Marx, D., Sikora, J. & Ward, H. B., Jun 29 2002, In : American Journal of Physiology - Heart and Circulatory Physiology. 282, 1 51-1

Research output: Contribution to journalArticle

Glycogen
Swine
Ischemia
Glucose
Hexokinase
54 Citations (Scopus)

Glutamate synthase: properties of the reduced nicotinamide adenine dinucleotide dependent enzyme from Saccharomyces cerevisiae

Roon, R. J., Even, H. L. & Larimore, F., Dec 1 1974, In : Journal of bacteriology. 118, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Glutamate Synthase
Glutamate Dehydrogenase
Glutamine
NAD
Glutamate Synthase (NADH)
96 Citations (Scopus)

Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb

Mi, N. L., Sang, H. H., Kim, J., Koh, A., Chang, S. L., Jung, H. K., Jeon, H., Kim, D. H., Suh, P. G. & Sung, H. R., Jul 1 2009, In : Molecular and cellular biology. 29, 14, p. 3991-4001 11 p.

Research output: Contribution to journalArticle

Glyceraldehyde-3-Phosphate Dehydrogenases
Sirolimus
Glucose
AMP-Activated Protein Kinases
Glyceraldehyde 3-Phosphate
17 Citations (Scopus)
Guanylate Cyclase
Cardiac Myocytes
Atrial Natriuretic Factor
Membranes
atrial natriuretic factor receptor A
164 Citations (Scopus)

Guanylyl Cyclase-linked Natriuretic Peptide Receptors: Structure and Regulation

Potter, L. R. & Hunter, T., Mar 2 2001, In : Journal of Biological Chemistry. 276, 9, p. 6057-6060 4 p.

Research output: Contribution to journalShort survey

Atrial Natriuretic Factor Receptors
Natriuretic Peptides
Peptide Receptors
Guanylate Cyclase
Glycosylation
3 Citations (Scopus)

Guanylyl cyclases

Potter, L. R., Dec 1 2010, Handbook of Cell Signaling, 2/e. Elsevier Inc., Vol. 2. p. 1399-1407 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Guanylate Cyclase
Natriuretic Peptides
Amino Acids
Endothelium-Dependent Relaxing Factors
Peptide Receptors
21 Citations (Scopus)

Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain

Robinson, J. W. & Potter, L. R., Sep 4 2012, In : Science Signaling. 5, 240, ra65.

Research output: Contribution to journalArticle

Dimers
Natriuretic Peptides
Guanosine Triphosphate
Catalytic Domain
Adenosine Triphosphate
132 Citations (Scopus)

Guanylyl cyclase structure, function and regulation

Potter, L. R., Dec 1 2011, In : Cellular Signalling. 23, 12, p. 1921-1926 6 p.

Research output: Contribution to journalReview article

Guanylate Cyclase
Cyclic GMP
Guanylate Cyclase-Activating Proteins
Nitric Oxide
Light Signal Transduction
8 Citations (Scopus)

GβL regulates TNFα-induced NF-k{cyrillic}B signaling by directly inhibiting the activation of Ik{cyrillic}B kinase

Kim, Y. L., Kim, J. E., Shin, K. J., Lee, S., Ahn, C., Chung, J., Kim, D-H., Seong, J. Y. & Hwang, J. I., Nov 1 2008, In : Cellular Signalling. 20, 11, p. 2127-2133 7 p.

Research output: Contribution to journalArticle

Leucine Zippers
Small Interfering RNA
Transcriptional Activation
Phosphotransferases
Down-Regulation
28 Citations (Scopus)

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

Ong, K. T., Mashek, M. T., Bu, S. Y. & Mashek, D. G., Jan 1 2013, In : FASEB Journal. 27, 1, p. 313-321 9 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Lipase
Liver
Triglycerides
Glucose
22 Citations (Scopus)

Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism

Ong, K. T., Mashek, M. T., Davidson, N. O. & Mashek, D., Jan 1 2014, In : Journal of Lipid Research. 55, 5, p. 808-815 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Lipase
Liver
Carrier Proteins
Fatty Acids
42 Citations (Scopus)

Hepatic fatty acid trafficking: Multiple forks in the road

Mashek, D. G., Jan 1 2013, In : Advances in Nutrition. 4, 6, p. 697-710 14 p.

Research output: Contribution to journalReview article

roads
Fatty Acids
fatty acids
liver
Liver
41 Citations (Scopus)

Hepatic lipid droplet biology: Getting to the root of fatty liver

Mashek, D. G., Khan, S. A., Sathyanarayan, A., Ploeger, J. M. & Franklin, M. P., Sep 1 2015, In : Hepatology. 62, 3, p. 964-967 4 p.

Research output: Contribution to journalArticle

Fatty Liver
Liver
Lipids
Organelles
Liver Diseases
59 Citations (Scopus)

Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways

Bu, S. Y. & Mashek, D., Nov 1 2010, In : Journal of Lipid Research. 51, 11, p. 3270-3280 11 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Fatty Acids
Liver
Fatty Acid Transport Proteins
RNA Interference
60 Citations (Scopus)

Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor α activity

Sapiro, J. M., Mashek, M. T., Greenberg, A. S. & Mashek, D., Sep 14 2009, In : Journal of Lipid Research. 50, 8, p. 1621-1629 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Hydrolysis
Triglycerides
Liver
Proteins
105 Citations (Scopus)

Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature

Olney, R. C., Bükülmez, H., Bartels, C. F., Prickett, T. C. R., Espiner, E. A., Potter, L. R. & Warman, M. L., Apr 1 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 4, p. 1229-1232 4 p.

Research output: Contribution to journalArticle

C-Type Natriuretic Peptide
Mutation
Insulin-Like Growth Factor I
Genes
Plasmas
34 Citations (Scopus)

Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature

Wang, S. R., Jacobsen, C. M., Carmichael, H., Edmund, A. B., Robinson, J. W., Olney, R. C., Miller, T. C., Moon, J. E., Mericq, V., Potter, L. R., Warman, M. L., Hirschhorn, J. N. & Dauber, A., Apr 1 2015, In : Human mutation. 36, 4, p. 474-481 8 p.

Research output: Contribution to journalArticle

Mutation
Haploinsufficiency
Genes
Observation
atrial natriuretic factor receptor B
34 Citations (Scopus)

Hexapeptide libraries for enhanced protein PTM identification and relative abundance profiling in whole human saliva

Bandhakavi, S., Van Riper, S. K., Tawfik, P. N., Stone, M. D., Haddad, T., Rhodus, N. L., Carlis, J. V. & Griffin, T. J., Mar 4 2011, In : Journal of Proteome Research. 10, 3, p. 1052-1061 10 p.

Research output: Contribution to journalArticle

Pulse time modulation
Saliva
Libraries
Workflow
Proteins
6 Citations (Scopus)

High-Affinity Transport of L-Glutamine by a Plasma Membrane Preparation from Rat Brain

Roon, R. J., Shofner, S. A. & Koerner, J. F., Jan 1 1989, In : Biochemistry. 28, 20, p. 8083-8087 5 p.

Research output: Contribution to journalArticle

Cell membranes
Glutamine
Rats
Brain
Cell Membrane
6 Citations (Scopus)

High frequency hearing loss and hyperactivity in DUX4 transgenic mice

Dandapat, A., Perrin, B. J., Cabelka, C., Razzoli, M., Ervasti, J. M., Bartolomucci, A., Lowe, D. A. & Kyba, M., Mar 2016, In : PloS one. 11, 3, e0151467.

Research output: Contribution to journalArticle

High-Frequency Hearing Loss
Audition
hearing
Transgenic Mice
Doxycycline
29 Citations (Scopus)

Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis

Bandhakavi, S., Xie, H., O'Callaghan, B., Sakurai, H., Kim, D. H. & Griffin, T. J., Feb 13 2008, In : PloS one. 3, 2, e1598.

Research output: Contribution to journalArticle

Oxidative stress
Sirolimus
Proteomics
proteomics
Yeast
18 Citations (Scopus)

Human B-type natriuretic peptide is not degraded by meprin A

Dickey, D. M. & Potter, L. R., Oct 1 2010, In : Biochemical Pharmacology. 80, 7, p. 1007-1011 5 p.

Research output: Contribution to journalArticle

meprin A
Brain Natriuretic Peptide
Rats
Neprilysin
Membranes

Human saliva proteome: An overview

Griffin, T. J., Jan 1 2014, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV. SPIE, Vol. 9112. 91120B

Research output: Chapter in Book/Report/Conference proceedingConference contribution

proteome
saliva
Proteome
proteins
Proteins
8 Citations (Scopus)

Identification and characterization of the ATP-binding site in human pancreatic glucokinase

Marotta, D. E., Anand, G. R., Anderson, T. A., Miller, S. P., Okar, D. A., Levitt, D. G. & Lange, A. J., Apr 1 2005, In : Archives of Biochemistry and Biophysics. 436, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

Glucokinase
Adenosine Triphosphate
Binding Sites
Glucose
Adenosine Diphosphate Glucose