Research Output 1973 2019

2019
3 Citations (Scopus)

BRASSINOSTEROID-SIGNALING KINASE 3, a plasma membrane-associated scaffold protein involved in early brassinosteroid signaling

Ren, H., Willige, B. C., Jaillais, Y., Geng, S., Park, M., Gray, W. M. & Chory, J., Jan 1 2019, In : PLoS genetics. 15, 1, e1007904.

Research output: Contribution to journalArticle

Brassinosteroids
scaffolding proteins
brassinosteroids
Blood Proteins
Membrane Proteins

Corrigendum: Persistent upregulation of the β-Tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle (Human Molecular Genetics (2019) 28:7 (1117-1135) DOI: 10.1093/hmg/ddy418)

Randazzo, D., Khalique, U., Belanto, J. J., Kenea, A., Talsness, D. M., Olthoff, J. T., Tran, M. D., Zaal, K. J., Pak, K., Pinal-Fernandez, I., Mammen, A. L., Sackett, D., Ervasti, J. M. & Ralston, E., Jun 1 2019, In : Human molecular genetics. 28, 11, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Medical Genetics
Tubulin
Microtubules
Regeneration
Molecular Biology
1 Citation (Scopus)

Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function

Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S. V., Higgins, L., Markowski, T. W., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B., Wendt, C. H. & Larsson, O., Aug 1 2019, In : American journal of respiratory and critical care medicine. 200, 3, p. 348-358 11 p.

Research output: Contribution to journalArticle

Gene Expression
Lung
Lung Neoplasms
Neoplasms
Sirolimus

Distinct mechanical properties in homologous spectrin-like repeats of utrophin

Rajaganapathy, S., McCourt, J. L., Ghosal, S., Lindsay, A., McCourt, P. M., Lowe, D. A., Ervasti, J. M. & salapaka, M. V., Dec 1 2019, In : Scientific reports. 9, 1, 5210.

Research output: Contribution to journalArticle

Open Access
Utrophin
Spectrin
Dystrophin
Dystroglycans
Connectin
Open Access
Adiposity
Insulin Resistance
Young Adult
Population
Body Mass Index
1 Citation (Scopus)

Dystrophinopathy-associated dysfunction of Krebs cycle metabolism

Lindsay, A., Chamberlain, C. M., Witthuhn, B. A., Lowe, D. A. & Ervasti, J. M., Jan 1 2019, In : Human molecular genetics. 28, 6, p. 942-951 10 p.

Research output: Contribution to journalArticle

Citric Acid Cycle
Succinic Acid
Dystrophin
Muscles
Inbred mdx Mouse
2 Citations (Scopus)

GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

Grunwald, D. S., Otto, N. M., Park, J-M., Song, D. & Kim, D-H., Jan 1 2019, In : Autophagy.

Research output: Contribution to journalArticle

Autophagy
Microtubule-Associated Proteins
GABA-A Receptors
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
1 Citation (Scopus)

Isometric resistance training increases strength and alters histopathology of dystrophin-deficient mouse skeletal muscle

Lindsay, A., Larson, A. A., Verma, M., Ervasti, J. M. & Lowe, D. A., Feb 1 2019, In : Journal of applied physiology. 126, 2, p. 363-375 13 p.

Research output: Contribution to journalArticle

Open Access
Dystrophin
Resistance Training
Duchenne Muscular Dystrophy
Skeletal Muscle
Muscles

metaQuantome: An Integrated, Quantitative Metaproteomics Approach Reveals Connections Between Taxonomy and Protein Function in Complex Microbiomes

Easterly, C. W., Sajulga, R., Mehta, S., Johnson, J. E., Kumar, P., Hubler, S., Mesuere, B., Rudney, J. D., Griffin, T. J. & Jagtap, P. D., Aug 9 2019, In : Molecular & cellular proteomics : MCP. 18, 8, p. S82-S91

Research output: Contribution to journalArticle

Open Access
Microbiota
Taxonomies
Benchmarking
Proteins
Galaxies
1 Citation (Scopus)

Multiomic Profiling of Tyrosine Kinase Inhibitor-Resistant K562 Cells Suggests Metabolic Reprogramming to Promote Cell Survival

Noel, B. M., Ouellette, S. B., Marholz, L., Dickey, D. M., Navis, C., Yang, T-Y., Nguyen, V., Parker, S. J., Bernlohr, D. A., Sachs, Z. & Parker, L. L., Apr 5 2019, In : Journal of Proteome Research. 18, 4, p. 1842-1856 15 p.

Research output: Contribution to journalArticle

K562 Cells
Protein-Tyrosine Kinases
Cell Survival
Cells
Proteomics

Mutation of a Conserved Motif of PP2C.D Phosphatases Confers SAUR Immunity and Constitutive Activity

Wong, J. H., Spartz, A. K., Park, M., Du, M. & Gray, W. M., Sep 1 2019, In : Plant physiology. 181, 1, p. 353-366 14 p.

Research output: Contribution to journalArticle

Open Access
Proton-Translocating ATPases
Phosphoric Monoester Hydrolases
Immunity
immunity
Cell Membrane
3 Citations (Scopus)

Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle

Randazzo, D., Khalique, U., Belanto, J. J., Kenea, A., Talsness, D. M., Olthoff, J. T., Tran, M. D., Zaal, K. J., Pak, K., Pinal-Fernandez, I., Mammen, A. L., Sackett, D., Ervasti, J. M. & Ralston, E., Jan 1 2019, In : Human molecular genetics. 28, 7, p. 1117-1135 19 p.

Research output: Contribution to journalArticle

Open Access
Tubulin
Microtubules
Regeneration
Up-Regulation
Muscles

Prescription patterns of anti-diabetic medications and clinical outcomes in Asian patients with heart failure and diabetes mellitus

on behalf of the ASIAN-HF Investigators, May 1 2019, In : European Journal of Heart Failure. 21, 5, p. 685-688 4 p.

Research output: Contribution to journalLetter

Prescriptions
Diabetes Mellitus
Heart Failure
2 Citations (Scopus)

Progress and Challenges in Ocean Metaproteomics and Proposed Best Practices for Data Sharing

Saito, M. A., Bertrand, E. M., Duffy, M. E., Gaylord, D. A., Held, N. A., Hervey, W. J., Hettich, R. L., Jagtap, P. D., Janech, M. G., Kinkade, D. B., Leary, D. H., McIlvin, M. R., Moore, E. K., Morris, R. M., Neely, B. A., Nunn, B. L., Saunders, J. K., Shepherd, A. I., Symmonds, N. I. & Walsh, D. A., Apr 5 2019, In : Journal of Proteome Research. 18, 4, p. 1461-1476 16 p.

Research output: Contribution to journalReview article

Information Dissemination
Practice Guidelines
Oceans and Seas
Carbon
Aquatic ecosystems
Subcellular Fractions
Prosencephalon
Knockout Mice
Intellectual Disability
Proteomics

QuanTP: A Software Resource for Quantitative Proteo-Transcriptomic Comparative Data Analysis and Informatics

Kumar, P., Panigrahi, P., Johnson, J. E., Weber, W. J., Mehta, S., Sajulga, R., Easterly, C., Crooker, B. A., Heydarian, M., Anamika, K., Griffin, T. J. & Jagtap, P. D., Feb 1 2019, In : Journal of Proteome Research. 18, 2, p. 782-790 9 p.

Research output: Contribution to journalArticle

Informatics
Galaxies
Software
Proteins
Visualization

The galaxy platform for reproducible affinity proteomic mass spectrometry data analysis

Stewart, P. A., Kuenzi, B. M., Mehta, S., Kumar, P., Johnson, J. E., Jagtap, P. D., Griffin, T. J. & Haura, E. B., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 249-261 13 p. (Methods in Molecular Biology; vol. 1977).

Research output: Chapter in Book/Report/Conference proceedingChapter

Galaxies
Proteomics
Mass Spectrometry
Workflow
Software
1 Citation (Scopus)
Guanylate Cyclase
Catalytic Domain
Adenosine Triphosphate
Substrates
Phosphotransferases

Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity

Foo, K. S., Skowronski, A. A., Baum, D., Firdessa-Fite, R., Thams, S., Shang, L., Creusot, R. J., LeDuc, C. A., Egli, D. & Leibel, R. L., Dec 1 2019, In : Scientific reports. 9, 1, 4965.

Research output: Contribution to journalArticle

Open Access
Inbred NOD Mouse
Fishes
Insulin
Autoimmunity
Epitopes
1 Citation (Scopus)

Unconventional secretion of adipocyte fatty acid binding protein 4 is mediated by autophagic proteins in a sirtuin-1-dependent manner

Josephrajan, A., Hertzel, A. M., Bohm, E. K., McBurney, M. W., Imai, S. I., Mashek, D., Kim, D. H. & Bernlohr, D. A., Sep 1 2019, In : Diabetes. 68, 9, p. 1767-1777 11 p.

Research output: Contribution to journalArticle

Sirtuin 1
Fatty Acid-Binding Proteins
Adipocytes
Proteins
Blood Proteins
1 Citation (Scopus)

Update on the moFF Algorithm for Label-Free Quantitative Proteomics

Argentini, A., Staes, A., Grüning, B., Mehta, S., Easterly, C., Griffin, T. J., Jagtap, P. D., Impens, F. & Martens, L., Feb 1 2019, In : Journal of Proteome Research. 18, 2, p. 728-731 4 p.

Research output: Contribution to journalArticle

Proteomics
Labels
Search Engine
Peptides
Workflow

Variable cytoplasmic actin expression impacts the sensitivity of different dystrophin-deficient mdx skeletal muscles to eccentric contraction

Lindsay, A., Southern, W. M., McCourt, P. M., Larson, A. A., Hodges, J. S., Lowe, D. A. & Ervasti, J. M., Jul 1 2019, In : FEBS Journal. 286, 13, p. 2562-2576 15 p.

Research output: Contribution to journalArticle

Utrophin
Dystrophin
Muscle
Actins
Skeletal Muscle
2018
7 Citations (Scopus)

A subset of plasma membrane-localized PP2C.D phosphatases negatively regulate SAUR-mediated cell expansion in Arabidopsis

Ren, H., Park, M., Spartz, A. K., Wong, J. H. & Gray, W. M., Jun 1 2018, In : PLoS genetics. 14, 6, e1007455.

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Arabidopsis
phosphatase
RNA
Indoleacetic Acids
Open Access
Dimercaprol
Respiratory Insufficiency
Fluids
4 Citations (Scopus)
Proteome
Chromosomes
Galaxies
Proteins
Workflow

Chronic Obstructive Pulmonary Disease Phenotype Dictates Cancer-Promoting Stromal Gene Expression Programs

Wendt, C. H., Sandri, B. J., Masvidal, L., Murie, C., Bartish, M., Avdulov, S. V., Higgins, L., Markowski, T., Peterson, M., Bergh, J., Yang, P., Rolny, C., Limper, A. H., Griffin, T. J., Bitterman, P. B. & Larsson, O., Dec 1 2018, In : Annals of the American Thoracic Society. 15, 4, p. S290-S291

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Phenotype
Gene Expression
Neoplasms
Lung Neoplasms
1 Citation (Scopus)

Community-Driven Data Analysis Training for Biology

Galaxy Training Network, Jun 27 2018, In : Cell Systems. 6, 6, p. 752-758.e1

Research output: Contribution to journalArticle

Open Access
Biological Science Disciplines
Web Browser
Research Personnel
Explosions
Internet
10 Citations (Scopus)

Disseminating metaproteomic informatics capabilities and knowledge using the galaxy-P framework

Blank, C., Easterly, C., Gruening, B., Johnson, J. E., Kolmeder, C. A., Kumar, P., May, D., Mehta, S., Mesuere, B., Brown, Z., Elias, J. E., Hervey, W. J., McGowan, T., Muth, T., Nunn, B. L., Rudney, J. D., Tanca, A., Griffin, T. J. & Jagtap, P. D., Mar 1 2018, In : Proteomes. 6, 1, 7.

Research output: Contribution to journalArticle

Open Access
Galaxies
Informatics
Workflow
Software
Microbiota
5 Citations (Scopus)

Dystrophin As a Molecular Shock Absorber

Le, S., Yu, M., Hovan, L., Zhao, Z., Ervasti, J. M. & Yan, J., Dec 26 2018, In : ACS nano. 12, 12, p. 12140-12148 9 p.

Research output: Contribution to journalArticle

shock absorbers
Shock absorbers
Dystrophin
Muscle
muscular function
2 Citations (Scopus)

Essential nucleotide- and protein-dependent functions of Actb/β-actin

Patrinostro, X., Roy, P., Lindsay, A., Chamberlain, C. M., Sundby, L. J., Starker, C., Voytas, D. F., Ervasti, J. M. & Perrin, B. J., Jul 31 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 31, p. 7973-7978 6 p.

Research output: Contribution to journalArticle

Actins
Nucleotides
Stereocilia
Proteins
High-Frequency Hearing Loss
Open Access
Papanicolaou Test
Microbiota
Fixatives
Protein Databases
Proteins
5 Citations (Scopus)

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms

O'Rourke, A. R., Lindsay, A. J., Tarpey, M. D., Yuen, S., McCourt, P., Nelson, D. M., Perrin, B. J., Thomas, D. D., Spangenburg, E. E., Lowe, D. A. & Ervasti, J. M., Feb 1 2018, In : FEBS Journal. 285, 3, p. 481-500 20 p.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Muscle Relaxation
Ablation
Muscle
Actins

Improve your Galaxy text life: The Query Tabular Tool [version 1; referees: 1 approved, 2 approved with reservations]

Johnson, J. E., Kumar, P., Easterly, C., Esler, M., Mehta, S., Eschenlauer, A. C., Hegeman, A. D., Jagtap, P. D. & Griffin, T. J., Jan 1 2018, In : F1000Research. 7, 1604.

Research output: Contribution to journalArticle

Open Access
Galaxies
Workflow
Software
Processing
Research Personnel

Integrative effects of dystrophin loss on metabolic function of the mdx mouse

Strakova, J., Kamdar, F. D., Kulhanek, D., Razzoli, M., Garry, D. J., Ervasti, J. M., Bartolomucci, A. & Townsend, D., Dec 1 2018, In : Scientific reports. 8, 1, 13624.

Research output: Contribution to journalArticle

Inbred mdx Mouse
Dystrophin
Duchenne Muscular Dystrophy
Skeletal Muscle
Fats
3 Citations (Scopus)

Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle

Olthoff, J. T., Lindsay, A., Abo-Zahrah, R., Baltgalvis, K. A., Patrinostro, X., Belanto, J. J., Yu, D. Y., Perrin, B. J., Garry, D. J., Rodney, G. G., Lowe, D. A. & Ervasti, J. M., Dec 1 2018, In : Nature communications. 9, 1, 5104.

Research output: Contribution to journalArticle

Peroxiredoxins
Dystrophin
eccentrics
muscles
contraction
5 Citations (Scopus)

Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with duchenne or becker muscular dystrophy

McCourt, J. L., Talsness, D. M., Lindsay, A., Arpke, R. W., Chatterton, P. D., Nelson, D. M., Chamberlain, C. M., Olthoff, J. T., Belanto, J. J., McCourt, P. M., Kyba, M., Lowe, D. A. & Ervasti, J. M., Feb 1 2018, In : Human molecular genetics. 27, 3, p. 451-462 12 p.

Research output: Contribution to journalArticle

Open Access
Dystrophin
Duchenne Muscular Dystrophy
Missense Mutation
Actins
Proteasome Endopeptidase Complex
2 Citations (Scopus)

Multi-omic molecular profiling of lung cancer in COPD

Sandri, B. J., Kaplan, A., Hodgson, S. W., Peterson, M., Avdulov, S. V., Higgins, L., Markowski, T., Yang, P., Limper, A. H., Griffin, T. J., Bitterman, P. B., Lock, E. & Wendt, C. H., Jul 1 2018, In : European Respiratory Journal. 52, 1, 1702665.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Lung Neoplasms
Neoplasms
Joints
Proto-Oncogene Proteins c-akt
8 Citations (Scopus)

Neopterin/7,8-dihydroneopterin is elevated in Duchenne muscular dystrophy patients and protects mdx skeletal muscle function

Lindsay, A., Schmiechen, A., Chamberlain, C. M., Ervasti, J. M. & Lowe, D. A., Jul 1 2018, In : Experimental Physiology. 103, 7, p. 995-1009 15 p.

Research output: Contribution to journalArticle

Open Access
Neopterin
Duchenne Muscular Dystrophy
Skeletal Muscle
Creatinine
Muscles
2 Citations (Scopus)

Plasma lipoproteome in Alzheimer's disease: A proof-of-concept study

Li, D., Huang, F., Zhao, Y., Villata, P. W., Griffin, T. J., Zhang, L., Li, L. & Yu, F., Sep 20 2018, In : Clinical Proteomics. 15, 1, 31.

Research output: Contribution to journalArticle

Alzheimer Disease
Plasmas
Lipoproteins
Peptides
Complement C3

Regulation of the natriuretic peptide receptor 2 (Npr2) by phosphorylation of juxtamembrane serine and threonine residues is essential for bifurcation of sensory axons

Schmidt, H., Dickey, D. M., Dumoulin, A., Octave, M., Robinson, J. W., Kühn, R., Feil, R., Potter, L. R. & Rathjen, F. G., Nov 7 2018, In : Journal of Neuroscience. 38, 45, p. 9768-9780 13 p.

Research output: Contribution to journalArticle

Natriuretic Peptides
Peptide Receptors
Threonine
Serine
Axons
6 Citations (Scopus)

Salivary proteomics of healthy dogs: An in depth catalog

Torres, S. M., Furrow, E., Souza, C. P., Granick, J. L., de Jong, E., Griffin, T. J. & Wang, X. S., Jan 1 2018, In : PloS one. 13, 1, e0191307.

Research output: Contribution to journalArticle

Proteomics
proteomics
Dogs
Peptides
Phylogeny
1 Citation (Scopus)

Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis

Muratore, K. A., Najt, C. P., Livezey, N. M., Marti, J., Mashek, D. & Arriaga, E., Jun 1 2018, In : Analytical and Bioanalytical Chemistry. 410, 16, p. 3629-3638 10 p.

Research output: Contribution to journalArticle

Geriatrics
Liver
Nanoparticles
Tissue
Lipids
17 Citations (Scopus)

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

Park, J-M., Seo, M., Jung, C. H., Grunwald, D., Stone, M., Otto, N. M., Toso, E., Ahn, Y., Kyba, M., Griffin, T. J., Higgins, L. & Kim, D-H., Apr 3 2018, In : Autophagy. 14, 4, p. 584-597 14 p.

Research output: Contribution to journalArticle

Autophagy
Phosphotransferases
Phosphorylation
Starvation
Amino Acids
12 Citations (Scopus)

Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins

Nelson, D. M., Lindsay, A., Judge, L. M., Duan, D., Chamberlain, J. S., Lowe, D. A. & Ervasti, J. M., Jun 15 2018, In : Human molecular genetics. 27, 12, p. 2090-2100 11 p.

Research output: Contribution to journalArticle

Dystrophin
Microtubules
Phenotype
Muscles
Inbred mdx Mouse
4 Citations (Scopus)

Xanthine oxidase is hyper-active in Duchenne muscular dystrophy

Lindsay, A., McCourt, P. M., Karachunski, P. I., Lowe, D. A. & Ervasti, J. M., Dec 1 2018, In : Free Radical Biology and Medicine. 129, p. 364-371 8 p.

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy
Xanthine Oxidase
Inbred mdx Mouse
Dystrophin
Muscle
2017
2 Citations (Scopus)

A coupled approach utilizing immunohistochemistry and immunocytochemistry to visualize cellular lipophagy

Sathyanarayan, A., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 185-191 7 p. (Methods in Molecular Biology; vol. 1554).

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunohistochemistry
Autophagy
Liver
Lipids
Molecular Imaging
7 Citations (Scopus)

Acyl-CoA thioesterase 1 (ACOT1) regulates PPARα to couple fatty acid flux with oxidative capacity during fasting

Franklin, M. P., Sathyanarayan, A. & Mashek, D., Aug 1 2017, In : Diabetes. 66, 8, p. 2112-2123 12 p.

Research output: Contribution to journalArticle

Open Access
Acyl Coenzyme A
Peroxisome Proliferator-Activated Receptors
Fasting
Fatty Acids
Liver
2 Citations (Scopus)

A glutamate-substituted mutant mimics the phosphorylated and active form of guanylyl cyclase-A

Otto, N. M., McDowell, W. G., Dickey, D. M. & Potter, L. R., Jul 1 2017, In : Molecular Pharmacology. 92, 1, p. 67-74 8 p.

Research output: Contribution to journalArticle

Glutamic Acid
Glutamates
Phosphorylation
atrial natriuretic factor receptor A
Phosphates
29 Citations (Scopus)

Breaking fat: The regulation and mechanisms of lipophagy

Schulze, R. J., Sathyanarayan, A. & Mashek, D., Oct 1 2017, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1862, 10, p. 1178-1187 10 p.

Research output: Contribution to journalReview article

Fats
Research
Metabolic Diseases
Liver
Lipid Droplets
3 Citations (Scopus)
Open Access
Adult Respiratory Distress Syndrome
Bronchoalveolar Lavage Fluid
Survivors
Proteins
Oxidative Stress