Projects per year
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Active
AI-Designed De Novo Mini-Proteins Coupled with Small Molecule Initiate Immune Cell-Mediated Eradication of PSMA-Expressing CRPC Cells
Deng, Y. (PI), Antonarakis, E. (CoI), Wagner, C. R. (CoI), Warlick, C. A. (CoI), Jin, F. (Other Role) & Singh, P. (Other Role)
6/1/25 → 5/31/27
Project: Research project
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MT2025-13 Long-term Follow-up of Subjects Who Received TRX103 in a Clinical Study Sponsored by Tr1X, Inc
Juckett, M. B. (PI)
4/9/25 → 4/8/36
Project: Research project
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A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent BetaThalassemia Who Received Reni-cel
Kao, R. L. (PI)
3/27/25 → 3/26/36
Project: Research project
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A Randomized, Double-blinded, Multiregional Phase 3 Study of IvonescimabVersus Pembrolizumab for the First-line Treatment of Metastatic Non-small Cell Lung Cancer in Patients Whose Tumors Demonstrate High PD-L1 Expression (HARMONi-7)
Haroun, F. S. (PI)
3/25/25 → 3/24/36
Project: Research project
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Targeting CRPC at the Intersection of Alternative Polyadenylation and Cellular Plasticity
Dehm, S. M. (PI), Antonarakis, E. (CoI), Hwang, J. (CoI), Drake, J. M. (Co-Principal Investigator) & Pang, H. (Co-Principal Investigator)
3/10/25 → 3/9/27
Project: Research project
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A Phase 2b, Open-Label, Two-cohort Study of Subcutaneous Amivantamab inCombination with Lazertinib as First-Line Treatment
Patel, M. R. (PI)
JANSSEN RESEARCH & DEVELOPMENT, LLC
2/6/25 → 10/17/35
Project: Research project
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MT2024-Phase 1 Study of FT522 in B-cell Mediated Autoimmune Diseases
Bachanova, V. (PI)
2/4/25 → 2/3/36
Project: Research project
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MT2024-42: Phase 1b Dose Expansion Study of NXC-201 for the Treatment of Patients with Relapsed or Refractory AL Amyloidosis.
Yohannan, B. (PI)
1/23/25 → 1/22/36
Project: Research project
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MT2024-12: A Phase 1 Study Evaluating BAFFR-targeting CAR T cells for Patients with Relapsed or Refractory B-cell Non-Hodgkin s Lymphoma (B-NHL)
Hu, M. (PI)
1/10/25 → 5/15/35
Project: Research project
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A PHASE 1, OPEN-LABEL, MULTICENTER STUDY OF JANX007 IN SUBJECTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER
Zorko, N. A. (PI)
1/3/25 → 1/2/36
Project: Research project
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A Phase 2 Multicenter Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Metastatic Non-Small-Cell Lung Cancer
Manning, B. M. (PI)
12/20/24 → 12/31/33
Project: Research project
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Efgartigimod Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)
Mazepa, M. (PI)
12/17/24 → 3/31/34
Project: Research project
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Discovery and validation of single cell biomarkers for clinical outcome in sickle cell disease
Wood, D. K. (PI), Datta, Y. H. (CoI), Gupta, A. O. (CoI) & Vercellotti, G. M. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
12/15/24 → 11/30/25
Project: Research project
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A Liquid Biopsy-Derived Proteogenomic Biomarker for 177Lu-PSMA Radioligand Therapy in Patients with Prostate Cancer
Antonarakis, E. (PI), Arafa, A. (CoI), Dehm, S. M. (CoI) & Drake, J. M. (CoI)
NOVARTIS PHARMACEUTICALS CORPORATION
12/13/24 → 10/1/26
Project: Research project
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A Phase 1a/b Study of ADRX-0405 in Subjects with Select Advanced Solid Tumors
Antonarakis, E. (PI)
11/25/24 → 11/24/35
Project: Research project
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HM2023-43: A phase 2 trial of tafasitamab in combination with lenalidomide+rituximab in treatment-naive follicular lymphoma and marginal zone lymphoma
Desai, S. (PI)
11/18/24 → 11/17/35
Project: Research project
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A Phase 3, Open-Label, Randomized Study of Perioperative Dostarlimab Monotherapy versus Standard ofCare in Participants with Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Prakash, A. (PI) & Lou, E. (Prior Principal Investigator)
11/13/24 → 1/31/34
Project: Research project
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Circumventing Pediatric Solid Tumor Microenvironment Resistance by Combinatorial CAR NK and Immunomodulating Therapy
Miller, J. S. (PI)
NEW YORK MEDICAL COLLEGE, ALEX'S LEMONADE STAND FOUNDATION
11/1/24 → 10/31/25
Project: Research project
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A phase 3 randomized, double-blind study of ianalumab (VAY736) versus placebo in addition toeltrombopag in patients with primary immune thrombocytopenia (ITP) who had an insufficient response orrelapsed after first line steroid treatment (VAYHIT2
Mazepa, M. (PI)
NOVARTIS PHARMACEUTICALS CORPORATION
10/31/24 → 3/31/34
Project: Research project
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MT2024-32: A Long-Term Follow-Up Study of Patients Who Received VOR33 and/or VCAR33A Long-Term Follow-Up Study of Patients Who Received VOR33 and/or VCAR33
Maakaron, J. (PI)
10/29/24 → 10/28/35
Project: Research project
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HM2024-36 A PHASE 3, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL OF QUIZARTINIB ADMINISTERED IN COMBINATION WITH INDUCTION AND CONSOLIDATION CHEMOTHERAPY...
Premnath, N. (PI)
10/29/24 → 10/28/35
Project: Research project
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A Phase 3 open-label, randomized, active-controlled, multicenter trial to evaluate the efficacy and safety of orally administered BAY 2927088...
Kratzke, R. A. (PI)
BAYER HEALTHCARE PHARMACEUTICALS
10/28/24 → 10/27/35
Project: Research project
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A Global, Open-label Study to Investigate the Efficacy and Safety ofSerpinPC in Subjects With Hemophilia B With Inhibitors
Reding, M. T. (PI)
10/15/24 → 10/14/35
Project: Research project
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Potentiation of Immune Checkpoint Blockade by Inhibition of Epoxyeicosatrienoic Acid Driven Tumor Respiration
Potter, D. A. (PI), Cao, Q. (Other Role) & Guo, Z. (Other Role)
10/1/24 → 9/30/25
Project: Research project
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Understanding the impact of survivorship care plans on health outcomes in cancer survivors
Blaes, A. H. (PI)
CENTERS FOR DISEASE CONTROL & PREVENTION
9/30/24 → 9/29/25
Project: Research project
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UNTOLD: UNderstanding The experience of Ovarian cancer - Life after Diagnosis: A Mixed Methods Approach
Vogel, R. (PI), Blaes, A. H. (CoI), Girard, A. (CoI), Teoh, D. G. (CoI) & Brown, K. (Other Role)
CENTERS FOR DISEASE CONTROL & PREVENTION
9/30/24 → 9/29/26
Project: Research project
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A global phase 3, randomised, double-blind and placebo-controlled study evaluating the efficacy and safety of etavopivat in adolescents and adults with sickle cell disease
Cogan, J. (PI)
9/25/24 → 9/24/35
Project: Research project
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A PHASE 2 STUDY OF ALISERTIB IN COMBINATION WITH ENDOCRINE THERAPY IN PATIENTS WITH HR+, HER2-NEGATIVE RECURRENT OR METASTATIC BREAST CANCER
Beckwith, H. C. (PI)
9/25/24 → 9/24/25
Project: Research project
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MT2023-34 A Safety and Effectiveness Registry Study of Patients with B-Thalassemia Treated with Betibeglogene Autotemcel
Kao, R. L. (PI)
9/4/24 → 9/30/33
Project: Research project
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BMT Core - University of Minnesota
Juckett, M. B. (PI), Ebens, C. (Co-Principal Investigator), Merino, A. M. (Other Role) & Miller, J. S. (Other Role)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
8/15/24 → 6/30/31
Project: Research project
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Phase 1b/3 global, randomized, controlled, open-label trial comparing treatment with RYZ101 to standardof care (SoC) therapy in subjects with inoperable, advanced, somatostatin receptor expressing (SSTR+),well-differentiated gastro-enteropancreatic
Greeno, E. W. (PI)
7/29/24 → 1/31/34
Project: Research project