Projects per year
- 1 - 50 out of 241 results
Search results
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Finished
Small-Molecule Penetration and Efflux in Gram-Negative Bacteria
Duerfeldt, A. S. (PI)
MEMORIAL SLOAN-KETTERING CANCER CENTER, NATIONAL INSTITUTES OF HEALTH (NIH)
3/1/24 → 1/31/25
Project: Research project
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TLR7/8 agonist design and delivery for effective anticancer immune response
Ferguson, D. M. (PI)
UNIVERSITY OF WASHINGTON, NATIONAL INSTITUTES OF HEALTH (NIH)
1/1/24 → 12/31/24
Project: Research project
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Wnt-beta-Catenin Project Chemical Biology Consortium 2 months
Georg, G. (PI), Gurvich, V. J. (CoI) & Tretyakova, N. Y. (CoI)
LEIDOS BIOMEDICAL RESEARCH, INC., NATIONAL INSTITUTES OF HEALTH (NIH)
9/1/23 → 2/28/25
Project: Research project
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Discovery and development of allosteric inhibitors of Cdk2/cyclin E as non-toxic ovarian cancer drugs
Georg, G. (PI) & Wong, H. L. (CoI)
7/1/23 → 12/31/24
Project: Research project
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Fermentation and Purification of MedM
Aldrich, C. (PI)
PROKARYOTICS INC, NATIONAL INSTITUTES OF HEALTH (NIH)
2/15/23 → 8/31/24
Project: Research project
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Design and Synthesis of TLR7, TLR8, and NLRP3 Immunostimulatory Agents
Ferguson, D. M. (PI)
1/17/23 → 1/31/24
Project: Research project
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Synthetic Chemistry Support for the TDB Medicinal Chemistry Team
Gurvich, V. J. (PI) & Georg, G. (CoI)
9/28/22 → 9/27/24
Project: Research project
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A Novel Small Molecule for The Prevention and Treatment of Diabetic Retinopathy
Duerfeldt, A. S. (PI)
EXCITANT THERAPEUTICS LLC, NATIONAL INSTITUTES OF HEALTH (NIH)
9/1/22 → 6/30/24
Project: Research project
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The Fundamental Investigation and Application of a Novel Self-Assembling Peptide in Chemotherapeutic Drug Delivery
Bentz, N. M. (PI)
AMERICAN FDN FOR PHARMACEUTICAL EDUC
9/1/22 → 8/31/23
Project: Research project
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Chemical Probe Development for Bromodomain and PHD Finger-containing Transcription Factor (BPTF) Utilizing Biophysical Assays
Buchholz, C. R. (PI)
AMERICAN FDN FOR PHARMACEUTICAL EDUC
9/1/22 → 8/31/23
Project: Research project
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MASTER: Chemical Biology Consortium
Georg, G. (PI) & Gurvich, V. J. (CoI)
LEIDOS BIOMEDICAL RESEARCH, INC., NIH NATIONAL CANCER INSTITUTE (NCI)
8/31/22 → 8/30/23
Project: Research project
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NCI P01 Project 3
Aihara, H. (PI) & Harki, D. A. (CoI)
UT HEALTH SCIENCE CENTER SAN ANTONIO, NATIONAL INSTITUTES OF HEALTH (NIH)
8/1/22 → 7/31/24
Project: Research project
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Discovery and development of allosteric inhibitors of Cdk2/cyclin E as non-toxic ovarian cancer drugs
Georg, G. (PI), Hawkinson, J. (CoI) & Wong, H. L. (CoI)
7/1/22 → 6/30/23
Project: Research project
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Biochar as a tool for preventing root infection of soybean seedlings by Macrophomina phaseolina andother soil fungi
Shier, T. (PI)
USDA AGRICULTURAL RESEARCH SERVICE, MISSISSIPPI SOYBEAN PROMOTION BOARD
10/1/21 → 1/31/22
Project: Research project
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Development/Validation of Rete Testis Microcannulation for the Assessment of Novel Chemical Scaffolds That Penetrate the Blood Testis Barrier
Wong, H. L. (PI) & Georg, G. (CoI)
NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV
9/17/21 → 9/16/23
Project: Research project
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Development of Probes to Characterize the Role of HINT1 in Mu Opioid Receptor and N-Methyl-D-Aspartate Receptor Cross-Regulation
Dillenburg, M. D. (PI)
AMERICAN FDN FOR PHARMACEUTICAL EDUC
9/1/21 → 8/31/22
Project: Research project
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Predictive Models for Small-Molecule Accumulation in Gram-Negative Bacteria
Duerfeldt, A. S. (PI)
MEMORIAL SLOAN-KETTERING CANCER CENTER, NATIONAL INSTITUTES OF HEALTH (NIH)
8/1/21 → 7/31/24
Project: Research project
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Identification of novel dual-acting bactericidal drug targets for tuberculosis treatment
Baughn, A. (PI) & Aldrich, C. (CoI)
FUJITA HEALTH UNIVERSITY, GLOBAL HEALTH INNOVATIVE TECHNOLOGY FUND
7/6/21 → 1/31/25
Project: Research project
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Harnessing N-Myc Signaling by Chemical Degradation of Aurora Kinase A
Harki, D. A. (PI)
AMERICAN ASSOCIATION FOR CANCER RESEARCH
7/1/21 → 6/30/22
Project: Research project
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A novel TNFR1-selective small molecule inhibitor to treat rheumatoid arthritis and related inflammatory diseases
Binstadt, B. A. (PI), Sachs, J. N. (CoI) & Ferguson, D. M. (Other Role)
RHEUMATOLOGY RESEARCH FOUNDATION
7/1/21 → 6/30/24
Project: Research project
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Mycotoxin production by the soybean red leaf blotch fungus Coniothyrium glycines
Shier, T. (PI)
USDA AGRICULTURAL RESEARCH SERVICE
4/7/21 → 4/30/24
Project: Research project
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Chemical probes as allosteric modulators of CK2 alpha prime targeting Huntington's disease
Walters, M. A. (PI), Finzel, B. C. (CoI) & Nelson, K. (Prior Principal Investigator)
NIH NAT INST OF NEURO DISORDERS & STROKE
2/15/21 → 1/31/23
Project: Research project
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Drug Discovery Pipeline Targeting Pathologically Leaky Calcium Release Channels in Age-Related Indications
Aldrich, C. (PI)
PHOTONIC PHARMA LLC, NATIONAL INSTITUTES OF HEALTH (NIH)
1/15/21 → 12/31/22
Project: Research project
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Development of New Alpha 4 Inhibitor Compound and Selectivity Assay for Male Contraception
Georg, G. (PI), Hawkinson, J. (CoI) & Wong, H. L. (CoI)
1/5/21 → 7/1/22
Project: Research project
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A Novel Small Molecule for The Prevention and Treatment of Diabetic Retinopathy
Duerfeldt, A. S. (PI)
EXCITANT THERAPEUTICS LLC, NATIONAL INSTITUTES OF HEALTH (NIH)
1/1/21 → 2/28/22
Project: Research project
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Rifamycins for NTM and PROTACS for mycobacteria
Aldrich, C. (PI)
HACKENSACK MERIDIAN HEALTH, INC
1/1/21 → 12/31/22
Project: Research project
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A Novel Small Molecule for The Prevention and Treatment of Age-Related Macular Degeneration
Duerfeldt, A. S. (PI)
EXCITANT THERAPEUTICS LLC, NATIONAL INSTITUTES OF HEALTH (NIH)
1/1/21 → 8/31/22
Project: Research project
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Evaluating therapeutic potential of a novel PPAR-a agonist for wet-AMD
Duerfeldt, A. S. (PI)
EXCITANT THERAPEUTICS LLC, NATIONAL INSTITUTES OF HEALTH (NIH)
1/1/21 → 2/28/22
Project: Research project
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The Role of HIF1A-DNMT3A axis in AML1/ETO-Driven Acute Myelogenous Leukemia
Liu, S. (PI), Tretyakova, N. Y. (CoI) & Yang, R. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
12/7/20 → 8/28/22
Project: Research project
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Chemical Methods to Characterize Penicillin-Binding Protein Function and Interactions
Carlson, E. E. (PI) & Ambrose, E. A. (CoI)
NIH NIGMS NATL INST OF GENERAL
9/18/20 → 6/30/24
Project: Research project
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Development of Methods for the Efficient Capture and Analysis of Circulating Breast Cancer Tumor Cells
Wagner, C. R. (PI)
MAYO CLINIC ROCHESTER, NIH NATIONAL CANCER INSTITUTE (NCI)
9/1/20 → 8/31/21
Project: Research project
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Structural Dynamics of Muscle Calcium ATPase Regulation
Thomas, D. D. (PI), Aihara, H. (CoI), Cornea, R. L. (Co-Principal Investigator) & Aldrich, C. (Consultant/Collaborator)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/20 → 4/30/24
Project: Research project
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Identification of mycotoxins used in soybean root infection by Macrophomina phaseolina and other fungi
Shier, T. (PI)
MISSISSIPPI STATE UNIVERSITY, MISSISSIPPI SOYBEAN PROMOTION BOARD
4/1/20 → 3/31/21
Project: Research project
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Time-resolved FRET-based allostery sensors for any protein kinase drug target
Levinson, N. M. (PI), Drake, J. M. (CoI), Georg, G. (CoI) & Thomas, D. D. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
3/1/20 → 2/29/24
Project: Research project
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Membrane-active quinoline and quinazoline antibacterials that target Gram positive pathogens
Aldrich, C. (PI)
DARTMOUTH COLLEGE, NATIONAL INSTITUTES OF HEALTH (NIH)
3/1/20 → 2/28/25
Project: Research project
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Functions of CD177 as a novel IgG Fc receptor
Wu, J. (PI) & Hawkinson, J. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
2/21/20 → 1/31/23
Project: Research project
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Overcoming Pyrazinamide Resistance with Pyrazinoate-Cephalosporin Conjugates
Aldrich, C. (PI), Baughn, A. (CoI) & Ferguson, D. M. (CoI)
NIH Nat'l Inst of Allergy & Infect Dis
1/25/20 → 12/31/21
Project: Research project
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Mechanisms of PhIP-induced dopaminergic neurotoxicity
Turesky, R. (PI)
PURDUE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
10/1/19 → 5/31/22
Project: Research project
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Optimization of the Composition of Corn Starch-based Bioplastic to ControlAflatoxin and Other Agricultural Pests
Shier, T. (PI)
USDA AGRICULTURAL RESEARCH SERVICE
10/1/19 → 6/30/21
Project: Research project
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D3 Antagonist for Substance Use Disorder
Gurvich, V. J. (PI), Georg, G. (CoI) & Walters, M. A. (CoI)
9/26/19 → 9/25/21
Project: Research project
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Allosteric CDK2 inhibitor Discovery and Development for Male Contraception
Georg, G. (PI) & Wong, H. L. (CoI)
NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV
9/13/19 → 8/31/21
Project: Research project
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Minnesota HHEAR Targeted Analysis Laboratory
Peterson, L. A. (PI), Balbo, S. (CoI), Gross, M. D. (CoI), Hecht, S. S. (CoI), Murphy, S. E. (CoI), Stepanov, I. (CoI), Turesky, R. (CoI) & Villalta, P. W. (CoI)
NIH NATL INST OF ENVIRON HEALTH SCIENCES
9/5/19 → 3/31/25
Project: Research project
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Profiling DNA adducts in formalin fixed paraffin embedded human colorectal tissue
Turesky, R. (PI) & Yun, B. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
9/1/19 → 8/31/22
Project: Research project
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APOBEC MUTAGENESIS IN BREAST CANCER
Harris, R. (PI), Aihara, H. (CoI), Harki, D. A. (CoI), Largaespada, D. A. (CoI) & Yee, D. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
8/9/19 → 7/31/22
Project: Research project
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Chemical Inhibition of APOBEC-catalyzed Tumor Evolution
Harki, D. A. (PI)
AMERICAN ASSOCIATION FOR CANCER RESEARCH
7/1/19 → 6/30/20
Project: Research project
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Development of Allosteric Inhibitors against Cyclin-Dependent Kinase 2 (Cdk2)
Faber, E. (PI)
NIH NATIONAL CANCER INSTITUTE (NCI)
7/1/19 → 6/30/22
Project: Research project
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NF-kappaB Inducing Kinase (NIK) for the Treatment of Hematologic Malignancies
Tang, J. (PI)
7/1/19 → 6/30/21
Project: Research project
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Target based discovery of next generation pyrazinamide
Aldrich, C. (PI)
HACKENSACK MERIDIAN HEALTH, INC, NATIONAL INSTITUTES OF HEALTH (NIH)
6/1/19 → 5/31/23
Project: Research project