Fingerprint Dive into the research topics where Medicinal Chemistry is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Opioid Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Narcotic Antagonists Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Melanocortins Medicine & Life Sciences
DNA Adducts Medicine & Life Sciences
Melanocortin Receptors Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences

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Profiles

No photo of Danielle N Adank

Danielle N Adank

Person: Research Support

No photo of Eyup Akgun

Eyup Akgun

Person: Researcher

19792019
No photo of Courtney Aldrich

Courtney Aldrich

Person: Faculty

20002023

Projects 1982 2024

2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

MASTER: CRO Support for NCATS Medicinal Chemistry for Lead Optimization

Gurvich, V. J., Georg, G., Hawkinson, J., Walters, M. A. & Wong, H. L.

NIHNIDA NATL INST ON DRUG AB

9/26/199/25/24

Project: Research project

Pharmaceutical Chemistry
Lead
National Center for Advancing Translational Sciences (U.S.)

Research Output 1961 2019

1,3-Butadiene metabolite 1,2,3,4 diepoxybutane induces DNA adducts and micronuclei but not t(9;22) translocations in human cells

Walker, V. E., Degner, A., Carter, E. W., Nicklas, J. A., Walker, D. M., Tretyakova, N. Y. & Albertini, R. J., Oct 1 2019, In : Chemico-Biological Interactions. 312, 108797.

Research output: Contribution to journalArticle

Open Access
DNA Adducts
HL-60 Cells
Cytotoxicity
Metabolites
Philadelphia Chromosome

7-methylation of chenodeoxycholic acid derivatives yields a substantial increase in TGR5 receptor potency

Nakhi, A., Mcdermott, C. M., Stoltz, K. L., John, K., Hawkinson, J. E., Ambrose, E. A., Khoruts, A., Sadowsky, M. J. & Dosa, P. I., Jul 25 2019, In : Journal of Medicinal Chemistry. 62, 14, p. 6824-6830 7 p.

Research output: Contribution to journalArticle

Chenodeoxycholic Acid
Methylation
Inflammatory Bowel Diseases
Hydroxyl Radical
Type 2 Diabetes Mellitus
1 Citation (Scopus)

A Cinchona Alkaloid Antibiotic That Appears to Target ATP Synthase in Streptococcus pneumoniae

Wang, X., Zeng, Y., Sheng, L., Larson, P., Liu, X., Zou, X., Wang, S., Guo, K., Ma, C., Zhang, G., Cui, H., Ferguson, D. M., Li, Y., Zhang, J. & Aldrich, C. C., Mar 14 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2305-2332 28 p.

Research output: Contribution to journalArticle

Cinchona Alkaloids
Quinuclidines
Streptococcus pneumoniae
Adenosine Triphosphate
Anti-Bacterial Agents