Masonic Cancer Center

Active

2/1/23 → 1/31/27

Project: Research project

Reversing osteosarcoma immunosuppression with targeted immunotherapy

Lawrence, J. (PI), Demos-Davies, K. M. (CoI), Rendahl, A. (CoI), Seelig, D. (CoI), Sloan, L. (CoI), Vallera, D. A. (CoI), Walcheck, B. (CoI) & Wolf-Ringwall, A. L. (CoI)

MORRIS ANIMAL FOUNDATION

2/1/23 → 5/30/25

Project: Research project

Molecular Signatures of Biologic Behavior in Pediatric Osteosarcoma

Makielski, K. M. (PI), Modiano, J. (CoI) & Robbins, P. D. (CoI)

NATIONAL INSTITUTES OF HEALTH (NIH)

2/1/23 → 11/30/27

Project: Research project

Utilizing the PS Gene Editing System to Encode a Blood-Brain Barrier-Penetrating IDUA as a Treatment for Murine Hurler Syndrome

Przybilla, M. (PI) & Whitley, C. B. (CoI)

UNIVERSITY OF PENNSYLVANIA

2/1/23 → 1/31/25

Project: Research project

Primary cilia loss in bile duct cells; the interplay with the autophagy machinery

Gradilone, S. (PI)

NIH NATL INST OF DIABETES/DIG/KIDNEY DIS

2/1/23 → 1/31/27

Project: Research project

Evaluating Cigarette Relighting Behavior: Prevalence, Correlates, Toxicant Exposure, and Implications forCessation

Stepanov, I. (PI)

RUTGERS UNIVERSITY, NIH NATIONAL CANCER INSTITUTE (NCI)

2/1/23 → 1/31/26

Project: Research project

Targeting senescent astrocytes in age-accelerated murine tauopathy models

Niedernhofer, L. J. (PI)

MERCK, SHARP & DOHME LLC

1/31/23 → 1/31/26

Project: Research project

Role of Gas6-Axl-MERTK in Myeloproliferative Neoplasm Thrombosis

Beckman, J. D. (PI)

MPN RESEARCH FOUNDATION

1/27/23 → 1/26/25

Project: Research project

Arandomized, double-blind, placebo-controlled Phase 3 study of darolutamide plus androgen deprivationtherapy (ADT) compared with placebo plus ADT in patients with high-risk biochemical recurrence (BCR) ofprostate cancer

Antonarakis, E. (PI)

BAYER HEALTHCARE PHARMACEUTICALS

1/24/23 → 1/31/28

Project: Research project

A Phase III, adjudicator-blinded, randomised study toevaluate the efficacy and safety of treatment with olorofimversus treatment with AmBisome? followed by standard ofcare (SOC) in patients with invasive fungal disease (IFD)caused by Aspergillus spec

Young, J.-A. H. (PI)

F2G LTD

1/19/23 → 1/31/28

Project: Research project

Genomic and functional approaches to characterize Chr1q gains in cancer

Sun, R. (PI)

YALE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)

1/18/23 → 12/31/24

Project: Research project

phase II trial evaluating the safety and efficacy of MTT in peanut allergic subjects

Khoruts, A. (PI)

BOSTON CHILDREN'S HOSPITAL, FOOD ALLERGY FUND

1/15/23 → 1/14/27

Project: Research project

A multicenter, single arm, open-label trial to evaluate efficacy and safety of oral, twice daily iptacopan in adult PNH patients who have Hb>10 g/dL in response to anti-C5 antibody and switch and iptacopanadult PNH patients who have Hb >=10 g/dL in respo

Beckman, J. D. (PI)

NOVARTIS PHARMACEUTICALS CORPORATION

1/14/23 → 2/3/26

Project: Research project

A Phase 2b study of TAK-755 (rADAMTS13) with minimal to no PEX in the treatment of patients with iTTP

Vercellotti, G. M. (PI)

TAKEDA DEVELOPMENT CENTER AMERICAS, INC.

1/5/23 → 6/30/25

Project: Research project

Cardiac and carotid structure and function in patients withMucopolysaccharidosis type VII

Dengel, D. R. (PI) & Rudser, K. (CoI)

SAINT LOUIS UNIVERSITY, ULTRAGENYX PHARMACEUTICAL INC.

1/3/23 → 1/2/26

Project: Research project

Resources for Drosophila embryo cryopreservation at lab and stock center scale

Bischof, J. C. (PI)

NIH Office of the Director

1/1/23 → 12/31/26

Project: Research project

Stratifying Patient Immune Endotypes in Sepsis (SPIES study)

Griffith, T. S. (PI) & Gould, R. W. (CoI)

UNIVERSITY OF FLORIDA, NATIONAL INSTITUTES OF HEALTH (NIH)

1/1/23 → 6/30/25

Project: Research project

Extracellular Vesicles as Potential Biomarkers and Therapeutic Target in Gaucher Disease

Kartha, R. (PI) & Subramanian, S. (CoI)

TAKEDA CAMBRIDGE LTD

1/1/23 → 7/31/25

Project: Research project

Development of NK Cell Therapeutics

Miller, J. S. (PI)

FATE THERAPEUTICS, INC.

1/1/23 → 12/31/25

Project: Research project

Formation and function of lamellipodial morphology in 3D microenvironments

Driscoll, M. K. (PI)

NIH NIGMS NATL INST OF GENERAL

1/1/23 → 12/31/25

Project: Research project

A multicenter, placebo-controlled field study evaluating gilvetmab in dogs with malignant melanoma

Borgatti, A. M. (PI)

MERCK

1/1/23 → 12/31/26

Project: Research project

Targeting Oncogenic PELP1/SRC-3 Signaling Complexes in ER+ Breast Cancer

Truong, T. H. (PI)

NIH NATIONAL CANCER INSTITUTE (NCI)

1/1/23 → 12/31/25

Project: Research project

Home Alone: Developing a Home-Based Intervention for People with Cognitive Impairment Who Live Alone

Gaugler, J. E. (PI)

NIH NAT'L INSTITUTE ON AGING (NIA)

1/1/23 → 6/30/25

Project: Research project

Complement and Pain in Sickle Cell Disease

Belcher, J. D. (PI) & Vercellotti, G. M. (CoI)

Omeros Corporation

1/1/23 → 12/31/24

Project: Research project

Characterization of Mandibular Osteoclast Progenitors during Physiological and Bone Healing

Mansky, K. (PI) & Bradley, E. W. (CoI)

OSTEO SCIENCE FOUNDATION INC

1/1/23 → 12/31/24

Project: Research project

A RANDOMIZED, DOUBLE-BLIND, VEHICLE-CONTROLLED, PARALLEL GROUP, MULTI-DOSE STUDY TOEVALUATE THE EFFICACY AND SAFETY OF TDM-105795 IN MALE SUBJECTS WITH ANDROGENETICALOPECIA

Hordinsky, M. K. (PI)

TECHNODERMA MEDICINES INC.

12/29/22 → 12/31/27

Project: Research project

Quantification of total PFAS concentrations and PFAS binding using 19F-nuclear magnetic resonance spectroscopy

Peterson, J. M. (PI), Arnold, B. (CoI) & Pomerantz, W. C. (CoI)

USDI U.S. GEOLOGICAL SURVEY

12/19/22 → 12/18/24

Project: Research project

NIA Academic Leadership Career Award K07

Gaugler, J. E. (PI)

NIH NAT'L INSTITUTE ON AGING (NIA)

12/15/22 → 11/30/27

Project: Research project

Advanced Oncolytic Adenovirus Enabling Systemic Therapy of PDAC

Yamamoto, M. (PI), Dahlman, M. S. (CoI) & Jensen, E. H. (CoI)

NIH NATIONAL CANCER INSTITUTE (NCI)

12/12/22 → 11/30/27

Project: Research project

PRE-I-SPY TRIAL - PRE-Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging AndmoLecular Analysis: A Phase I/Ib platform trial

Potter, D. A. (PI)

QUANTUM LEAP HEALTH CARE COLLABORATIVE

12/6/22 → 12/31/27

Project: Research project

A Phase 1b, Randomized, Vehicle-Controlled, Double-Blind, Pharmacokinetics, Pharmacodynamics, and Safety Study of ARQ-255 Topical Suspension in Healthy Volunteers and Subjects with Alopecia Areata

Hordinsky, M. K. (PI)

ARCUTIS BIOTHERAPEUTICS, INC

12/6/22 → 6/30/25

Project: Research project

Minnesota Craniofacial and Oral Health Research Experience (MnCORE)

Mansky, K. (PI)

NIH NIDCR NATL INST OF DENTAL

12/5/22 → 11/30/27

Project: Research project

Fundamental investigation and characterization on Iron Nitride magnetic Thin Films

Wang, J.-P. (PI)

NIRON MAGNETICS, INC.

12/1/22 → 1/31/25

Project: Research project

Role of adipose tissue inflammaging and metabolic dysfunction during sepsis

Camell, C. (PI)

NIH NAT'L INSTITUTE ON AGING (NIA)

12/1/22 → 11/30/27

Project: Research project

Predictive biomarkers and new therapeutic strategies to prevent EGFR TKI-refractory lung cancer progression

Hoeppner, L. H. (PI), Klein, M. A. (CoI) & Patel, M. R. (CoI)

LUNG CANCER RESEARCH FOUNDATION

12/1/22 → 5/31/26

Project: Research project

A phase 3, randomized, double-blind, study to assess efficacy and safety of ianalumab (VAY736) versus placebo in warm autoimmune hemolytic anemia (wAIHA) patients who failed at least one line of treatment(VAYHIA)

Vercellotti, G. M. (PI)

NOVARTIS PHARMACEUTICALS CORPORATION

12/1/22 → 4/11/30

Project: Research project

Targeting early events in prostate cancer lineage plasticity

Dehm, S. M. (PI), Huang, R. S. S. (CoI), Munro, S. A. (CoI) & Murugan, P. (CoI)

NIH NATIONAL CANCER INSTITUTE (NCI)

12/1/22 → 11/30/27

Project: Research project

Blue Light Cystoscopy with Cysview (BLC with Cysview) Registry

Ahmadi, H. (PI), Regmi, S. K. (CoI) & Warlick, C. A. (CoI)

PHOTOCURE INC

11/29/22 → 3/31/28

Project: Research project

A Phase 1/2, First-in-Human, Multicenter, Open-Label Study of SQZ-eAPC-HPV as Monotherapy and in Combinationwith Immune Checkpoint Inhibitor(s) in Patients with HPV16+ Recurrent, Locally Advanced, or Metastatic SolidTumors

Fujioka, N. (PI)

SQZ BIOTECHNOLOGIES COMPANY

11/23/22 → 11/23/27

Project: Research project

MT2022-57: A Phase 1, Open-Label, Multicenter, Dose Escalation and Cohort Expansion Study of theSafety and Efficacy of Anti-CD70 Allogeneic CRISPR-Cas9-Engineered T Cells (CTX130) in Adult SubjectsWith Relapsed or Refractory T or B Cell Malignancies

Maakaron, J. (PI)

CRISPR THERAPEUTICS, INC

11/18/22 → 11/18/27

Project: Research project

Multiplex Engineered CAR-NK Cells Targeting B7-H3 to Treat Metastatic Castration Resistant Prostate Cancers

Zorko, N. A. (PI)

PROSTATE CANCER FOUNDATION

11/15/22 → 11/14/25

Project: Research project

FT576-101: A Phase I Study of FT576 as Monotherapy and in Combination with Daratumumab in Subjects with Relapsed/Refractory Multiple Myeloma 576

Merino, A. M. (PI)

FATE THERAPEUTICS, INC.

11/15/22 → 11/15/27

Project: Research project

A Phase III study of JR-141 in Mucopolysaccharidosis type II (Hunter Syndrome) patients

Whitley, C. B. (PI) & Miller, B. S. (CoI)

JCR PHARMACEUTICALS

11/15/22 → 11/16/25

Project: Research project

Mechanistic insight into genome stability pathways

Largaespada, D. A. (PI)

UNIVERSITY OF VIRGINIA, NIH NIGMS NATL INST OF GENERAL

11/15/22 → 5/31/26

Project: Research project

M4OC-Prevent 2.0: Phase IIb Trial of Metformin for Oral Cancer Prevention

Ondrey, F. G. (PI)

THE UNIVERSITY OF ARIZONA, NIH NATIONAL CANCER INSTITUTE (NCI)

11/15/22 → 7/31/25

Project: Research project

ATYR1923-C-004: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TOEVALUATE THE EFFICACY AND SAFETY OF INTRAVENOUS EFZOFITIMOD IN PATIENTS WITHPULMONARY SARCOIDOSIS

Bhargava, M. (PI)

ATYR PHARMA, INC

11/9/22 → 9/1/25

Project: Research project

A Phase 2/3, Randomized, Open-label, Study of MGC018 Versus Androgen Receptor Axis-targeted Therapy (Abiraterone or Enzalutamide) in Participants with Metastatic Castration-resistant Prostate Cancer

Antonarakis, E. (PI)

MACROGENICS INC

11/3/22 → 11/3/27

Project: Research project

A PHASE 1/2 SINGLE ARM OPEN-LABEL CLINICAL TRIAL OF TC-510 IN PATIENTS WITH ADVANCED MESOTHELIN-EXPRESSING CANCER

Prakash, A. (PI)

TCR2 THERAPEUTICS INC

11/1/22 → 11/30/27

Project: Research project

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant RecipientsTransplant Recipients

Thielen, B. K. (PI)

ARKANSAS CHILDREN'S RESEARCH INSTITUTE, NIH Nat'l Inst of Allergy & Infect Dis

10/27/22 → 8/31/26

Project: Research project

Indefinite-Delivery-Indefinite-Quantity (IDIQ)

Borgatti, A. M. (PI)

LEIDOS BIOMEDICAL RESEARCH, INC., NIH NATIONAL CANCER INSTITUTE (NCI)

10/27/22 → 6/30/25

Project: Research project

Masonic Cancer Center

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