Masonic Cancer Center

Active

Penetrating the "Black Box": Prediction of Early Bronchiolitis obliterans in Pediatric Hematopoietic StemCell Transplant Recipients

Goldfarb, S. (PI) & MacMillan, M. L. (CoI)

CINCINNATI CHILDREN'S HOSPITAL MED CTR, NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

7/15/21 → 4/30/26

Project: Research project

Targeting N-Myc with Selective Aurora Kinase A Degraders for Neuroblastoma Therapy

Harki, D. A. (PI), Harris, R. (CoI) & Levinson, N. M. (CoI)

U.S. DEPARTMENT OF DEFENSE

7/15/21 → 7/14/25

Project: Research project

Mentoring and Research in Patient-Oriented Cardiovascular Pharmacoepidemiology

Lutsey, P. L. (PI)

NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

7/15/21 → 6/30/26

Project: Research project

Vertical Sleeve Gastrectomy for Treatment of NASH: a pilot randomized control trial

Ikramuddin, S. (PI), Adeyi, O. (CoI), Billington, C. J. (CoI), Connett, J. E. (CoI), Holker, E. G. (CoI), Klatt, N. R. (CoI) & Lake, J. R. (CoI)

NIH NATL INST OF DIABETES/DIG/KIDNEY DIS

7/14/21 → 5/31/25

Project: Research project

Understanding the functional agility of effector memory CD8 T cells

Hamilton Hart, S. E. (PI)

NIH Nat'l Inst of Allergy & Infect Dis

7/9/21 → 6/30/26

Project: Research project

Minimal Clinically Important Difference in FACITFatigueScale in patients with locally advanced ormetastatic breast cancer receiving treatment withtaxane-based chemotherapy

Blaes, A. H. (PI)

DOMPE S.P.A

7/8/21 → 7/31/26

Project: Research project

Dompe farmaceutici s.p.a. - REP0121, A multicenter, randomized, doubleblind, placebo-controlled phase 2study to assess the efficacy and safety of oralreparixin in cancer related fatigue in patients with locally advanced ormetastatic breast cancer und

Blaes, A. H. (PI)

DOMPE S.P.A

7/8/21 → 7/31/26

Project: Research project

Minnesota Partnership for Biotechnology and Medical Genomics

Bischof, J. C. (PI) & LeBien, T. W. (Prior Principal Investigator)

STATE OF MINNESOTA

7/1/21 → 2/1/25

Project: Research project

Evolutionary dynamics of non-genetic mechanisms of drug resistance in cancer

Foo, J. Y. (PI)

THE NATIONAL SCIENCE FOUNDATION

7/1/21 → 6/30/25

Project: Research project

Targeting AR and AR-Variants in Castration-Resistant Prostate Cancer

Dehm, S. M. (PI)

TEXAS A & M UNIVERSITY, NIH NATIONAL CANCER INSTITUTE (NCI)

7/1/21 → 1/31/25

Project: Research project

The role of the microbiome in the outcome of human respiratory viral infections

Thielen, B. K. (PI)

MERCK AND CO INC

7/1/21 → 2/20/25

Project: Research project

Schwertfeger - ACS IRG Competitive Renewal

Stepanov, I. (PI) & Schwertfeger, K. (Prior Principal Investigator)

AMERICAN CANCER SOCIETY, INC

7/1/21 → 6/30/26

Project: Research project

Neighborhood Park Youth Sports Program Fee Waiver and Intensive Family Outreach to Promote Physical Activity in Low-Income Children Ages 6-12 Years

French, S. A. (PI), Barr-Anderson, D. J. (CoI), Fan, Y. (CoI), Maclehose, R. F. (CoI) & Sherwood, N. E. (CoI)

NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

7/1/21 → 6/30/26

Project: Research project

Summer Research Program for Diversity Students in PharmacoNeuroImmunology

Molitor, T. W. (PI), Carroll, D. M. (CoI), Gewirtz, J. C. (CoI), Hatsukami, D. K. (CoI) & Pravetoni, M. (CoI)

NIH NIDA NATL INST ON DRUG AB

7/1/21 → 5/31/26

Project: Research project

Effect of Mucosal Immune Stimulation on Mammary Gland Immune Responses During the Dry Period and Early Lactation Period in Dairy Cows

Caixeta, L. (PI), Crooker, B. A. (CoI), Godden, S. M. (CoI), Noyes, N. (CoI) & Walcheck, B. (CoI)

USDA Nat'l Inst. of Food & Agriculture

7/1/21 → 6/30/25

Project: Research project

Structure-based design of coronavirus subunit vaccines

Li, F. (PI)

GEORGIA STATE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)

7/1/21 → 4/30/25

Project: Research project

Mayo / UMN Partnership in Regenerative Medicine

Bischof, J. C. (PI) & LeBien, T. W. (Prior Principal Investigator)

STATE OF MINNESOTA

7/1/21 → 6/30/26

Project: Research project

Developing a multiscale understanding of biophysical processes in sickle cell disease

Wood, D. K. (PI), Beckman, J. D. (CoI), Datta, Y. H. (CoI), Odde, D. J. (CoI) & Vercellotti, G. M. (CoI)

NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

7/1/21 → 5/31/25

Project: Research project

Bcl11b: A Master Transcription Factor Controlling Human NK Cell Development

Cichocki, F. M. (PI), Eaton, A. (CoI), Felices, M. (CoI) & Wang, J. (CoI)

NIH NAT'L HEART, LUNG, AND BLOOD INSTITU

7/1/21 → 4/30/26

Project: Research project

Initiation, growth, and resistance mechanisms of EGFR-mutated lung adenocarcinoma

Hoeppner, L. H. (PI)

AMERICAN CANCER SOCIETY, INC

7/1/21 → 12/31/25

Project: Research project

Calprotectin-mediated CD69 signaling in periodontitis

Costalonga, M. (PI), Bittner-Eddy, P. (CoI), Herzberg, M. C. (CoI), Jameson, S. C. (CoI), Guan, W. (Other Role) & Johnstone, K. F. (Other Role)

NIH NIDCR NATL INST OF DENTAL

7/1/21 → 3/31/26

Project: Research project

Anti-G-CSFR Monoclonal Antibodies to Treat Sickle Cell Disease

Belcher, J. D. (PI) & Vercellotti, G. M. (CoI)

CSL BEHRING GMBH

6/30/21 → 12/5/26

Project: Research project

A Phase 1/2 Study of [225Ac]-FPI-1434 Injection in Patients with Locally Advanced or Metastatic SolidTumours

Yee, D. (PI)

FUSION PHARMACEUTICALS INC

6/22/21 → 6/30/26

Project: Research project

Identifying and preventing antigen specific T cells in diabetes

Fife, B. T. (PI), Farrar, M. A. (CoI) & Spanier, J. A. (CoI)

NIH Nat'l Inst of Allergy & Infect Dis

6/22/21 → 5/31/26

Project: Research project

Reducing cervical cancer screening disparities in Somali immigrant women through a primary case-based HPV self-sampling intervention

Pratt, R. J. (PI), Ghebre, R. G. (CoI), Ramer, T. J. (CoI) & Yohe, S. L. (CoI)

NIH NATIONAL CANCER INSTITUTE (NCI)

6/15/21 → 5/31/26

Project: Research project

TLR7/8 agonist design and delivery for effective anticancer immune response

Ferguson, D. M. (PI) & Griffith, T. S. (CoI)

TEMPLE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)

6/8/21 → 5/31/26

Project: Research project

A Multicenter, Open-label, Extension Study of theSafety and Tolerability of Sitravatinib Alone or inCombination with Other Anticancer Therapies inPatients with Advanced or Metastatic SolidMalignancies

Patel, M. R. (PI)

MIRATI THERAPEUTICS, INC.

6/7/21 → 5/31/26

Project: Research project

Phase 1, Multi-Center, Open-Label Study of VT3989 in Patients withRefractory Locally Advanced or Metastatic Solid Tumors Enriched forTumors Harboring Mutations of the Neurofibromatosis Type 2 Gene (mutantNF2 or mNF2)

Kratzke, R. A. (PI)

VIVACE THERAPEUTICS, INC.

6/7/21 → 5/31/26

Project: Research project

MT2021-18: Prospective observational study of the immunogenicity of vaccines for severe acuterespiratory syndrome coronavirus 2 (sars-cov-2) after autologous hematopoietic stem cell transplantation(hct), allogeneic hct, and chimeric antigen re

Young, J.-A. H. (PI)

NATIONAL MARROW DONOR PROGRAM

6/1/21 → 4/15/25

Project: Research project

A Single-Arm Clinical Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant CV01 Delivery of Sonodynamic Therapy (SDT) in Pet Dogs with Suspected Primary High-Grade Glioma

Pluhar, L. (PI)

ALPHEUS MEDICAL, INC

6/1/21 → 5/31/25

Project: Research project

Nuclear Receptor Regulation of Epigenetics in Endocrine-Related Cancers

Gillis, N. (PI) & Yee, D. (Other Role)

NIH NATIONAL CANCER INSTITUTE (NCI)

6/1/21 → 5/31/25

Project: Research project

Next-Generation fMRI with MB-SWIFT: Insights into the Origins of Contrast

Mangia, S. (PI), Adriany, G. (CoI), Garwood, M. (CoI), Idiyatullin, D. S. (CoI) & Michaeli, S. (Co-Principal Investigator)

NIH NAT'L INSTITUTE OF MENTAL HEALTH

6/1/21 → 4/30/25

Project: Research project

Skeletal Muscle Regeneration from Pluripotent Stem Cells

Perlingeiro, R. (PI)

NIH NIAMS NATL INST OF ARTHRIT

6/1/21 → 5/31/26

Project: Research project

A PHASE I/II, DOSE-ESCALATION STUDY OFMGTA-117 IN PATIENTS WITH ADULT ACUTEMYELOID LEUKEMIA (AML) ANDMYELODYSPLASIA-EXCESS BLASTS (MDS-EB)

Juckett, M. B. (PI)

MAGENTA THERAPEUTICS

5/27/21 → 4/30/26

Project: Research project

A MULTICENTER, OPEN-LABEL, EXTENSION STUDY TO ASSESS THE LONGTERM SAFETY ANDEFFICACY OF CTP-543 IN ADULT PATIENTS WITHMODERATE TO SEVERE ALOPECIA AREATA

Hordinsky, M. K. (PI)

CONCERT PHARMACEUTICALS, INC.

5/20/21 → 5/31/26

Project: Research project

A Phase IB/II Multi-Cohort Study of Targeted Agents with Atezolizumab for Patients with Recurrent orPersistent Endometrial Cancer

Erickson, B. K. (PI)

ALLIANCE FOUNDATION TRIALS, LLC

5/19/21 → 5/31/26

Project: Research project

Sensory Function and Chronic Pain in Cerebral Palsy

Symons, F. J. (PI), Erickson, D. J. (CoI), Panoskaltsis-Mortari, A. (CoI), Simone, D. A. (CoI), Walk, D. (CoI) & Wilcox, G. L. (CoI)

NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

5/14/21 → 2/28/27

Project: Research project

A Phase 1/2 Open-label, Multicenter, Dose Escalation and Dose ExpansionStudy of the Safety, Tolerability, and Pharmacokinetics of HPN328 in Patientswith Advanced Cancers Associated with Expression of Delta-Like CanonicalNotch Ligand 3 (DLL3) Who Have

Fujioka, N. (PI)

HARPOON THERAPEUTICS, INC.

5/1/21 → 4/30/26

Project: Research project

Stress and Opioid Misuse Risk: The Role of Endogenous Opioid and Endocannabinoid Mechanisms

al'Absi, M. N. (PI)

VANDERBILT UNIVERSITY MEDICAL CENTER, NIH NIDA NATL INST ON DRUG AB

5/1/21 → 2/28/26

Project: Research project

Longitudinal Relationships Among Sleep, Cognition, and Azheimer's Disease Biomarkers: Discerning Causal Assocations, Mediators, and Susceptibility

Pankow, J. (PI) & Lutsey, P. L. (CoI)

BRIGHAM AND WOMEN'S HOSPITAL, NATIONAL INSTITUTES OF HEALTH (NIH)

5/1/21 → 2/28/25

Project: Research project

Phase 1 First-in-Human Study of Leukocyte Immunoglobulin-Like Receptor B2 (LILRB2) Inhibitor Monoclonal Antibody (mAb) JTX-8064, as Monotherapy and in Combination with a Programmed Cell Death Receptor-1 (PD-1) Inhibitor, in Adult Subjectswith Advanced

Teoh, D. G. (PI)

JOUNCE THERAPEUTICS, INC

5/1/21 → 4/30/26

Project: Research project

Emergence of a complex biochemical system: Evolutionary aspects of the path to coded protein synthesis

Seelig, B. (PI)

NASA GODDARD SPACE FLIGHT CTR

5/1/21 → 4/30/26

Project: Research project

CD4 T cell dysfunction and reprogramming during sepsis

Griffith, T. S. (PI), Khoruts, A. (CoI), Lusczek, E. R. (CoI) & Staley, C. (CoI)

NIH NIGMS NATL INST OF GENERAL

5/1/21 → 4/30/26

Project: Research project

ACTIV-3 INSIGHT 016 - VATICO-SARS-CoV-2 vaccination strategies in previously hospitalized and recovered COVID-19 patients

Reilly, C. S. (PI) & Neaton, J. (Prior Principal Investigator)

LEIDOS BIOMEDICAL RESEARCH, INC., NIH NATIONAL CANCER INSTITUTE (NCI)

5/1/21 → 4/30/25

Project: Research project

Phase 2 multicenter, randomized, double-blind, placebo-controlled, multiple dosing interval, 3-period studyof the safety, tolerability and effectiveness of adoptively transferred Viralym-M multivirus-specific T cells inkidney transplant recipients w

Young, J.-A. H. (PI)

ALLOVIR, INC

4/28/21 → 11/30/25

Project: Research project

Aeterna Zentaris DETECT: MULTICENTER, OPEN LABEL TRIAL TO INVESTIGATE THE EFFICACY AND SAFETY OF A SINGLE ORAL DOSE OF 1.0 MG/KG MACIMORELIN ACETATE AS GROWTH HORMONE STIMULATION TEST (GHST) IN PEDIATRIC PATIENTS WITH SUSPECTED GROWTH HORMONEDEFICIENCY

Miller, B. S. (PI)

AETERNA ZENTARIS, INC.

4/22/21 → 4/30/26

Project: Research project

An Open-label, Single-arm, Multicohort, Phase 2 Study to Assess the Efficacy and Safety ofTabelecleucel in Subjects with Epstein-Barr Virus-associated Diseases

Maakaron, J. (PI)

ATARA BIOTHERAPEUTICS, INC

4/20/21 → 4/30/26

Project: Research project

Skeletal Muscle Molecular Drug Targets for Exercise-induced Cardiometabolic Health

Aliferis, MD, PhD, C. (PI), Ma, S. (CoI) & Wang, J. (CoI)

DUKE UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)

4/20/21 → 3/31/25

Project: Research project

Messaging strategies to reduce breast cancer over-screening in older women

Gollust, S. E. (PI) & Nagler, R. H. (CoI)

JOHNS HOPKINS UNIVERSITY, NIH NAT'L INSTITUTE ON AGING (NIA)

4/15/21 → 3/31/25

Project: Research project

Development of Enabling Technologies for Clinical Ultrahigh Field Body MRI

Metzger, G. (PI), Adriany, G. (CoI), Koopmeiners, J. (CoI), Li, X. (CoI), Spilseth, B. D. (CoI), Warlick, C. A. (CoI), Wu, X. (CoI) & Erturk, A. (Consultant/Collaborator)

NIH NATL INST OF BIOMEDICAL IM

4/15/21 → 12/31/25

Project: Research project

Masonic Cancer Center

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