Masonic Cancer Center

Active

ARIC Neurocognitive Study (ARIC-NCS) Renewal 2023-2028

Lutsey, P. L. (PI), Lakshminarayan, K. (CoI), Sedaghat, S. (CoI) & Thyagarajan, B. (CoI)

NEW YORK UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)

4/1/24 → 3/31/29

Project: Research project

Study 1: PK/PD and target engagement analysis

Belcher, J. D. (PI)

CELLARITY, INC

4/1/24 → 3/31/25

Project: Research project

Midwest Center for Occupational Health and Safety Training Grant

Arnold, S. (PI), Alexander, B. H. (CoI), Baker, B. A. (CoI), Everson-Rose, S. (CoI), Feyen, R. G. (CoI), Hurley, S. J. (CoI), Huynh, T. B. (CoI), Kim, H. (CoI), Maclehose, R. F. (CoI), Porta, C. M. (CoI), Raynor, P. C. (CoI) & Schofield, K. E. (CoI)

CDC NAT'L INST FOR OCCUP SAFETY & HEALTH

3/29/24 → 6/30/25

Project: Research project

A Phase 3b, Multicenter, Single-arm, Expanded Access Protocol of Tarlatamab (AMG 757) for theTreatment of Subjects with Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment

Kratzke, R. A. (PI)

AMGEN INC

3/29/24 → 3/31/34

Project: Research project

A Phase 2, Double-blind, Dose-Ranging, Parallel, Long-term Extension Study to Evaluate the Safety andEfficacy of Enpatoran in Participants with Subacute Cutaneous Lupus Erythematosus, Discoid LupusErythematosus and/or Systemic Lupus Erythematosus Havin

Pearson, D. R. (PI)

MERCK AND CO INC

3/26/24 → 11/30/33

Project: Research project

A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)

Thenappan, T. (PI) & Reding, M. T. (Prior Principal Investigator)

TENAX THERAPEUTICS, INC

3/20/24 → 3/19/33

Project: Research project

White matter-associated striatal astrocytes and their role in apathy in Huntington?s disease

Gomez-Pastor, R. (PI)

NIH NAT INST OF NEURO DISORDERS & STROKE

3/15/24 → 2/28/26

Project: Research project

A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in SubjectsWith Relapsed Small Cell Lung Cancer After Platinum-based First-line Chemotherapy (DeLLphi-304)

Kratzke, R. A. (PI)

AMGEN INC

3/12/24 → 5/31/28

Project: Research project

The role of senescent cells in dysregulating immune responses and pathogen control

Jameson, S. C. (PI), Camell, C. (CoI), Dong, X. (CoI), Hamilton Hart, S. E. (CoI), Masopust, D. (CoI), Niedernhofer, L. J. (CoI), Revelo, X. (CoI) & Robbins, P. D. (CoI)

NIH Nat'l Inst of Allergy & Infect Dis

3/11/24 → 2/28/29

Project: Research project

NCARL Sequencing Projects

Beckman, K. B. (PI)

USDA AGRICULTURAL RESEARCH SERVICE

3/7/24 → 2/26/25

Project: Research project

Phase 1 Clinical Trial of Myogenic Progenitors for DMD

Kang, P. B. (PI), Cheng, E. Y. (CoI), Karachunski, P. I. (CoI), McKenna, D. H. (CoI), Perlingeiro, R. (CoI) & Wagner, J. E. (CoI)

DUCHENNE UK

3/4/24 → 3/3/27

Project: Research project

Development of nanomaterials for ultrasound-mediated destruction of metastatic ovarian tumors

Azarin, S. M. (PI) & Boehnke, N. (CoI)

MN OVARIAN CANCER ALLIANCE

3/1/24 → 2/28/25

Project: Research project

Development of a RET-Specific Proteomic Assay from Circulating Tumor Cells in Lethal Prostate Cancer

Drake, J. M. (PI)

U.S. DEPARTMENT OF DEFENSE

3/1/24 → 2/28/27

Project: Research project

Coronary Artery Risk Development in Young Adults (CARDIA) Study - Central Biorepository Relocation

Thyagarajan, B. (PI)

THE UNIVERSITY OF ALABAMA, NATIONAL INSTITUTES OF HEALTH (NIH)

3/1/24 → 6/30/25

Project: Research project

Illuminating and Addressing Structural Racism in the Healthcare Industry: Building the Field from the Ground Up

Bailey, Z. (PI)

DREXEL UNIVERSITY, ROBERT WOOD JOHNSON FOUNDATION

3/1/24 → 2/28/27

Project: Research project

Center for Functional Genomics of Immunotherapy (CFGI)

Largaespada, D. A. (PI), Moriarity, B. S. (CoI) & Stromnes, I. M. (CoI)

STATE OF MINNESOTA

3/1/24 → 3/31/26

Project: Research project

Mechanisms of SGLT2 Inhibition in Pediatric NAFLD

Crawford, P. (PI), Chow, L. S. (CoI), Puchalska, P. (CoI) & Rudser, K. (CoI)

ANN & ROBERT H LURIE CHILDREN'S HOSPITAL, NATIONAL INSTITUTES OF HEALTH (NIH)

3/1/24 → 12/31/24

Project: Research project

Standardized Microbiota Transplant Therapy in Crohn???s Disease. Pilot Trial

Khoruts, A. (PI) & Vaughn, B. P. (CoI)

LEONA M & HARRY B HELMSLEY CHAR. TRUST

3/1/24 → 2/28/27

Project: Research project

Organoid Biomanufacturing for Transforming Healthcare

Ogle, B. M. (PI)

STATE OF MINNESOTA

3/1/24 → 3/31/26

Project: Research project

MHC & KIR Sequencing and Association Analyses in the iGeneTRAiN Studies

Pankratz, N. D. (PI)

NEW YORK UNIVERSITY, NIH Nat'l Inst of Allergy & Infect Dis

3/1/24 → 6/30/25

Project: Research project

Developing and Applying a Methodology for Assigning Heme and Non-Heme Iron Values to Foods in a Food and Nutrient Database and Dietary Assessment Software Used by Nutrition Researchers

Harnack, L. J. (PI)

NATIONAL CATTLEMEN'S BEEF ASSOCIATION

3/1/24 → 3/1/26

Project: Research project

A Phase III, Randomized, Controlled, Global Multicenter Study to Evaluate the Efficacy and Safety of OralTinengotinib versus Physician s Choice in Subjects with Fibroblast Growth Factor Receptor (FGFR)-altered, Chemotherapy- and FGFR Inhibitor-Refracto

Greeno, E. W. (PI)

TRANSTHERA SCIENCES (NANJING), INC.

2/26/24 → 2/28/34

Project: Research project

HAPPINESS: cHAnging the Perceived Pain INtensity in divErSe populations with Spinal cord injury: A feasibility study

Van de Winckel, A. L. (PI), Lim, K. O. (CoI) & Morse, L. (CoI)

NIH NATL CTR FOR COMPLEMENTARY

2/23/24 → 1/31/27

Project: Research project

First-in-human Phase I, non-randomized, open-label, multi-center dose escalation trial of BI 765049 and BI765049 + ezabenlimab administered by repeated intravenous infusions in patients with malignant solidtumors expressing B7-H6

Prakash, A. (PI)

BOEHRINGER-INGELHEIM PHARMACEUTICALS

2/21/24 → 2/28/34

Project: Research project

Novel functions of ESRRB in glioblastoma

Clarke, R. R. (PI) & Jin, L. (CoI)

GEORGETOWN UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)

2/8/24 → 1/31/25

Project: Research project

OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy

Blaes, A. H. (PI)

ALLIANCE FOR CLINICAL TRIALS IN ONCOLOGY, NATIONAL INSTITUTES OF HEALTH (NIH)

2/2/24 → 2/1/35

Project: Research project

Transforming treatment of inherited bone marrow failure in Fanconi anemia by in vivo precise genome editing

Moriarity, B. S. (PI), Wagner, J. E. (CoI) & Webber, B. R. (CoI)

FANCONI CANCER FOUNDATION

2/1/24 → 1/31/26

Project: Research project

A Randomized, Open-label, Phase 3 Study of Adjuvant Sacituzumab Govitecan and Pembrolizumab VersusTreatment of Physician s Choice in Patients With Triple Negative Breast Cancer Who Have ResidualInvasive Disease After Surgery and Neoadjuvant Therapy (AS

Blaes, A. H. (PI)

ALLIANCE FOUNDATION TRIALS, LLC, GILEAD SCIENCES, INC.

2/1/24 → 2/28/34

Project: Research project

Early detection of cancer disparity and treatment resistance in TNBC

Jansen, R. J. (PI)

EASTERN VIRGINIA MEDICAL SCHOOL, U.S. DEPARTMENT OF DEFENSE

2/1/24 → 1/31/27

Project: Research project

Cancer Center Support Grant

Yee, D. (PI), Antonarakis, E. (CoI), Beckman, K. B. (CoI), Betts, B. (CoI), Blaes, A. H. (CoI), Eaton, A. (CoI), Ellis, K. M. (CoI), Felices, M. (CoI), Geller, M. A. (CoI), Ghebre, R. G. (CoI), Griffin, T. J. (CoI), Hallstrom, T. C. (CoI), Harki, D. A. (CoI), Hatsukami, D. K. (CoI), Hirsch, B. A. (CoI), Huang, R. S. S. (CoI), Johnson, S. (CoI), Juckett, M. B. (CoI), Lange, C. A. (CoI), Le, C. T. (CoI), Luo, X. (CoI), McKenna, D. H. (CoI), Miller, J. S. (CoI), Moriarity, B. S. (CoI), Muretta, J. M. (CoI), Murray, T. (CoI), Nelson, H. H. (CoI), Ondrey, F. G. (CoI), Patel, M. R. (CoI), Pennell, C. A. (CoI), Petersen, A. J. (CoI), Peterson, L. A. (CoI), Poynter, J. (CoI), Pratt, R. J. (CoI), Sarver, A. L. (CoI), Schendzielos, D. L. (CoI), Schilz, A. (CoI), Schwertfeger, K. (CoI), Seelig, D. (CoI), Shimizu, Y. (CoI), Stepanov, I. (CoI), Temiz, N. A. (CoI), Ventz, S. (CoI), Villalta, P. W. (CoI), Vogel, R. (CoI), Wagner, J. E. (CoI), Wang, J. (CoI), Webber, B. R. (CoI), Weigel, B. J. (CoI), Yamamoto, M. (CoI) & Zhang, L. (CoI)

NIH NATIONAL CANCER INSTITUTE (NCI)

2/1/24 → 1/31/29

Project: Research project

Novel intervention approaches to alleviate allogeneic transplant-related morbidity and mortality

Juckett, M. B. (PI)

FRED HUTCHINSON CANCER CENTER, NATIONAL INSTITUTES OF HEALTH (NIH)

2/1/24 → 1/31/25

Project: Research project

Catsper inhibitors for male contraception

Georg, G. (PI) & Wong, H. L. (CoI)

NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

2/1/24 → 1/31/26

Project: Research project

Exploration of Novel SOT Materials for SOT Reader Applications

Wang, J.-P. (PI)

WESTERN DIGITAL CORPORATION

2/1/24 → 12/31/25

Project: Research project

Developing a P2 Healthy Nail Salon Recognition Program to Promote Safer and More Sustainable Beauty Products in two Minnesota EJ Communities

Huynh, T. B. (PI) & Arnold, S. (CoI)

U.S. ENVIRONMENTAL PROTECTION AGENCY

2/1/24 → 1/31/26

Project: Research project

Improving safety and access to immune effector cell therapy with artificial intelligence technology???

Bachanova, V. (PI)

NIH NATIONAL CANCER INSTITUTE (NCI)

2/1/24 → 1/31/26

Project: Research project

Technology to Realize the Full Potential of UHF MRI

Metzger, G. (PI), Adriany, G. (CoI), Akcakaya, M. (CoI), Auerbach, E. J. (CoI), Bolan, P. J. (CoI), Chen, W. (CoI), Eryaman, Y. (CoI), Hong, M. (CoI), Idiyatullin, D. S. (CoI), Kannan, M. (CoI), Kerlin, A. M. (CoI), Kobayashi, N. (CoI), Li, X. (CoI), Mangia, S. (CoI), Michaeli, S. (CoI), Moeller, S. (CoI), Sadeghi Tarakameh, A. (CoI), Tousi, Y. M. (CoI), Ugurbil, K. (CoI), Wu, X. (CoI) & Zimmermann, J. (CoI)

NIH NATL INST OF BIOMEDICAL IM

2/1/24 → 1/31/29

Project: Research project

CTSA K12 Program at University of Minnesota

Ingbar, D. H. (PI), Lim, K. O. (CoI) & Shippee, T. P. (CoI)

NATIONAL INSTITUTES OF HEALTH (NIH)

2/1/24 → 1/31/29

Project: Research project

MT2014-05: A Phase I, First in Human Open Label Study to Evaluate the Safety and Tolerability of TRX103cell infusion in subjects with hematological malignancies undergoing HLA-mismatched related orunrelated hematopoietic stem cell transplantation (HSCT

Juckett, M. B. (PI)

TR1X, INC

1/31/24 → 1/31/34

Project: Research project

A Randomized, Multicenter, Placebo-controlled, Phase 3 study to Evaluate the Efficacy and Safety ofHER2/neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/neu Positive Subjects with Residual Disease or High-Risk PCR after both Neoadjuvant and Postoperat

Blaes, A. H. (PI)

GREENWICH LIFESCIENCES, INC.

1/29/24 → 1/31/34

Project: Research project

Ice Control Enhancement with Closed Loop Molecular Design (ICECycle)

Hubel, A. (PI)

UNIVERSITY OF MICHIGAN, USDOD DEFENSE ADV RES PROJECTS

1/26/24 → 12/9/24

Project: Research project

A Study of the Genetic Determinants of Response to Growth Hormone (GH) Treatment in Children withIdiopathic Short Stature (ISS)

Miller, B. S. (PI)

NOVO NORDISK, INC.

1/26/24 → 2/28/34

Project: Research project

A Phase 3, Multi-center, Open-label Study to Test the Diagnostic Performance of Copper Cu 64 PSMA I&T PET/CT in Men with Biochemical Recurrence of Prostate Cancer

Antonarakis, E. (PI)

CURIUM

1/26/24 → 1/31/34

Project: Research project

Testis-Specific Serine Kinases 1-3 (TSSKs1-3) as targets for non-hormonal male contraception

Georg, G. (PI)

MALE CONTRACEPTION INITIATIVE

1/24/24 → 1/23/26

Project: Research project

OPTIMIZE: A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide as GvHDProphylaxis in Adult Patients with Hematologic Malignancies Receiving HLA-Mismatched Unrelated DonorPeripheral Blood Stem Cell Transplantation

Juckett, M. B. (PI)

NATIONAL MARROW DONOR PROGRAM

1/23/24 → 1/22/34

Project: Research project

Phase 1/2 Study of REGN5668 (MUC16 X CD28, a Costimulatory Bispecific) Administered in Combination with Cemiplimab or REGN4018 (MUC16 X CD3)

Geller, M. A. (PI)

REGENERON PHARMACEUTICALS, INC.

1/17/24 → 1/17/34

Project: Research project

Convergence Accelerator Track L: Innovative chemical microsensor development for in situ, real-time monitoring of priority water pollutants to protect water quality

Santelli, C. M. (PI), Chiang, Y.-Y. (CoI), Cui, T. (CoI) & Sartori, J. M. (CoI)

THE NATIONAL SCIENCE FOUNDATION

1/15/24 → 12/31/24

Project: Research project

AMPK Activators in Models of GvHD

Blazar, B. R. (PI)

KALLYOPE, INC

1/10/24 → 12/31/24

Project: Research project

UV-Curable Adhesives Based on Isoprene Carboxylates

Hoye, T. R. (PI)

APPLE, INC

1/8/24 → 1/7/25

Project: Research project

Outcomes of Fecal Microbiota Transplantation (FMT) for the Treatment of Uncomplicated Diverticulitis: aPilot Study

Khoruts, A. (PI)

UNIVERSITY OF MASSACHUSETTS

1/3/24 → 8/14/26

Project: Research project

Investigation of safety, tolerability, and efficacy of the near-infrared (NIR) heptamethine carbocyanine organic dye DZ conjugated to simvastatin in pet dogs with spontaneous high-grade gliomas

Arnold, S. A. (PI)

DA ZEN THERANOSTICS, INC

1/2/24 → 1/1/26

Project: Research project

Masonic Cancer Center

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