Laboratory Medicine and Pathology

Projects

Projects per year 1995 2009 2010 2014 2015 2016 2017 2018 2019 2020 2021 2022 2032

• 1 Not started
• 157 Active
• 645 Finished

Projects per year

Search results

• Full human gene-replacement mouse models of ADRDs

  Koob, M. D.

  NIH NAT INST OF NEURO DISORDERS & STROKE

  9/1/21 → 8/31/24

  Project: Research project

  • animal models 100%
  • genes 39%

• Full human gene-replacement mouse models of ADRDs

  Koob, M. D., Ebner, T. J., Liao, D. & Vossel, K. A.

  NIH NAT INST OF NEURO DISORDERS & STROKE

  9/18/19 → 8/31/21

  Project: Research project

  • animal models 100%
  • genes 39%

• Full human gene replacement mouse models of Alzheimer's Disease

  Koob, M. D.

  NIH NAT'L INSTITUTE ON AGING (NIA)

  9/1/22 → 8/31/25

  Project: Research project

  • Alzheimer Disease 100%
  • Genes 51%

• Functional Analysis of Low Copy Number Gain of Human 8q2

  Bagchi, A. & Schwertfeger, K.

  AMERICAN CANCER SOCIETY, INC.

  7/1/14 → 4/2/17

  Project: Research project

  • Functional analysis 100%

• Functions of ductal- and stromal-associated macrophages in the mammary gland

  Schwertfeger, K. & Nelson, A. C.

  Tulane University

  9/1/22 → 7/31/23

  Project: Research project

  • mammary glands 100%
  • macrophages 88%

• GBS Correlation of Protection Study

  Nyholm, J. L., Ferrieri, P. & Hoffman, S. L.

  MN DEPARTMENT OF HEALTH

  4/19/19 → 12/31/21

  Project: Research project

• GENCAC Central Biochemistry Laboratory

  Eckfeldt, J. H.

  National Heart, Lung, and Blood Institute

  9/17/01 → 8/31/08

  Project: Research project

  • biochemistry 100%

• Generating a wild type and apoptosis-deficient human Noxa expressing BAC transgenic mouse

  Kelekar, A. & Koob, M. D.

  NIH Nat'l Inst of Allergy & Infect Dis

  6/1/20 → 5/31/23

  Project: Research project

  • Noxae 100%
  • Transgenic Mice 60%
  • Apoptosis 41%

• Generation and function of "long-lived effector" memory

  Hamilton Hart, S. E., Hamilton Hart, S. E., Jameson, S. C. & Jameson, S. C.

  NIH Nat'l Inst of Allergy & Infect Dis

  2/19/15 → 1/31/21

  Project: Research project

  • Memory 100%
  • T-Lymphocytes 84%

• Gene Replacement Mouse Models of a Human Neurodegenerati

  Koob, M. D.

  MN MED FDN

  6/1/06 → 5/31/08

  Project: Research project

  • animal models 100%
  • neurodegenerative diseases 72%
  • genes 39%

• Genes of the CYP450-Derived Eicosanoids Pathway in Subcl

  Steffes, M. W.

  U OF TX HEALTH SCIENCE CTR. AT HOUSTON

  4/4/07 → 3/31/11

  Project: Research project

  • Eicosanoids 100%
  • Atherosclerosis 33%
  • Genes 33%

• Genetic & Epidemiologic Predictors of Glucose Homeostasis Measures in Hispanics

  Tsai, M. Y. & Eckfeldt, J. H.

  LUNDQUIST INSTITUTE FOR BIOMEDICAL INNO

  1/1/13 → 5/31/14

  Project: Research project

  • Hispanic Americans 100%
  • Homeostasis 76%
  • Glucose 65%

• Genetic Analysis of TGF-Beta signaling in the control of

  Moss-Taylor, L. D.

  AMERICAN HEART ASSOCIATION, INC.

  7/1/15 → 6/30/17

  Project: Research project

  • transforming growth factor beta 100%
  • genetic analysis 75%
  • animal development 54%

• Genetic and Environmental Determinants of Type 2 Diabete

  Pereira, M. A., Gross, M. D., Steffes, M. W., Yu, M. & Yuan, J.

  NIH Natl Inst of Diabetes/Dig/Kidney Dis

  3/1/09 → 2/29/16

  Project: Research project

  • Type 2 Diabetes Mellitus 100%

• Genetic Epidemiology of Casual Variants Across the Life

  Pankow, J. & Thyagarajan, B.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  9/1/13 → 5/31/16

  Project: Research project

  • Molecular Epidemiology 100%

• Genetic Epidemiology of Casual Variants Across the Life

  Pankow, J. & Gross, M. D.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  7/14/08 → 5/31/13

  Project: Research project

  • Molecular Epidemiology 100%

• Genetic Epidemiology of Causal Variants Across the Life

  Pankow, J. & Thyagarajan, B.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  6/1/16 → 5/31/17

  Project: Research project

  • Molecular Epidemiology 100%

• Genetic epidemiology of hematopoietic cell transplant ou

  Spector, L. G., Spector, L. G., Thyagarajan, B., Tolar, J. & Verneris, M. R.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  7/1/15 → 6/30/19

  Project: Research project

  • Molecular Epidemiology 100%
  • Transplants 53%

• Genetic Factors in Birth Defects-2014

  Tsai, M. Y.

  NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

  9/30/14 → 7/31/19

  Project: Research project

• Genetic Factors of Birth Defects-Genomics Testing

  Tsai, M. Y. & Pankratz, N. D.

  National Institutes of Health

  5/10/17 → 2/9/24

  Project: Research project

  • Genomics 100%

• Genetics of Fetal Growth and Related Traits

  Tsai, M. Y.

  NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

  9/29/16 → 3/28/18

  Project: Research project

  • fetal development 100%
  • growth traits 96%

• Genetic Susceptibility to Ototoxicity in Pediatric Germ Cell Tumor Survivors

  Poynter, J. & Pankratz, N. D.

  ALEX'S LEMONADE STAND FOUNDATION

  2/15/21 → 2/15/23

  Project: Research project

  • Ototoxicity 100%
  • Germ Cell and Embryonal Neoplasms 89%
  • Genetic Predisposition to Disease 77%
  • Pediatrics 48%

• Genetic Variation in Vitamin D Metabolism and BMT Outcom

  Robien, K., Lazovich, D., Ross, J. A. & Thyagarajan, B.

  National Institutes of Health

  9/26/08 → 8/31/11

  Project: Research project

  • vitamin D 100%
  • genetic variation 53%
  • metabolism 49%

• GenHAT

  Eckfeldt, J. H.

  National Heart, Lung, and Blood Institute

  7/1/07 → 9/30/12

  Project: Research project

• Genomic Scan for Atherosclerosis Pathway Genes in Africa

  Eckfeldt, J. H. & Foster, C.

  Washington University in St. Louis

  5/15/08 → 4/30/14

  Project: Research project

  • atherosclerosis 100%
  • African Americans 60%
  • genomics 56%
  • genes 30%

• Genomics of Pediatric Germ Cell Tumors

  Poynter, J. & Pankratz, N. D.

  ALEX'S LEMONADE STAND FOUNDATION

  7/1/17 → 6/30/19

  Project: Research project

  • Germ Cell and Embryonal Neoplasms 100%
  • Genomics 85%
  • Pediatrics 54%

• Genotyping Performance of DNA from Stored Serum: a Pilot

  Tsai, M. Y.

  NIH NAT'L INST OF CHILD HEALTH/HUMAN DEV

  9/22/17 → 12/20/19

  Project: Research project

  • genotyping 100%
  • DNA 53%

• Glucose and ROS responsive metabolic regulators

  Kelekar, A.

  University of Michigan

  8/1/13 → 8/31/16

  Project: Research project

  • Metabolic 100%
  • Glucose 90%

• Glycemia Reduction Approaches in Diabetes: A comparative

  Steffes, M. W., Li, D. & Saenger, A. K.

  George Washington University

  9/6/17 → 7/31/18

  Project: Research project

  • chronic illness 100%

• Glycemia Reduction Approaches in Diabetes: A comparative

  Steffes, M. W.

  George Washington University

  11/1/12 → 7/31/17

  Project: Research project

  • chronic illness 100%

• Glycemia Reduction Approaches in Diabetes: A comparative Effectiveness Study (GRADE)

  Steffes, M. W., Saenger, A. K. & Seegmiller, J. C.

  George Washington University

  8/1/18 → 7/31/19

  Project: Research project

  • chronic illness 100%

• Glycemia Reduction Approaches in Diabetes: A comparative Effectiveness Study (GRADE)

  Steffes, M. W. & Seegmiller, J. C.

  George Washington University

  8/1/19 → 7/31/23

  Project: Research project

  • chronic illness 100%

• Glycemic Observation and Metabolic Outcomes in Mothers and Offspring (GO MOMs).

  Steffes, M. W. & Killeen, A.

  Northwestern University

  9/20/20 → 7/31/23

  Project: Research project

  • Observation 100%

• Glycemic Observation Using A1C for Gestational Diabetes Diagnosis

  Steffes, M. W.

  Massachusetts General Hospital

  6/15/22 → 5/31/23

  Project: Research project

  • Medical problems 100%

• Glycemic Profile of Pregnancy Consortium Biostatistics Research Center

  Steffes, M. W.

  Northwestern University

  9/15/22 → 7/31/23

  Project: Research project

  • biostatistics 100%
  • pregnancy 41%

• GuLF Study PHR-SSS-S-21-005993

  Killeen, A.

  DLH HOLDINGS LLC

  3/17/21 → 5/30/21

  Project: Research project

• Harnessing CD8+ T cell antitumor responses by manipulati

  Borges da Silva, H.

  Cancer Research Institute

  7/1/18 → 8/9/19

  Project: Research project

  • T-Lymphocytes 100%
  • Adenosine Triphosphate 62%

• HDAC inhibitor sensitization of BRCA-1/2 mutant and wild-type high-grade serous ovarian cancer cells to PARP inhibitor treatment

  Thomas, S.

  Mayo Clinic

  9/15/21 → 8/31/23

  Project: Research project

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Histone Deacetylase Inhibitors 88%
  • Ovarian Neoplasms 68%

• HDAC inhibitor sensitization of BRCA-1/2 wild-type high-grade serous ovarian cancer cells to PARPinhibitor treatment (Supplemental Non-Federal Funds)

  Thomas, S.

  Mayo Clinic

  9/15/22 → 8/31/23

  Project: Research project

  • Histone Deacetylase Inhibitors 100%
  • Financial Management 97%
  • Ovarian Neoplasms 77%
  • Poly(ADP-ribose) Polymerase Inhibitors 56%

• Health and Retirement Study: Harmonized Cognitive Assessment Protocol (HCAP)

  Thyagarajan, B.

  University of Michigan

  9/15/20 → 12/31/22

  Project: Research project

  • retirement 100%
  • health 47%

• Health and Retirement Study Yr29-34:

  Thyagarajan, B.

  University of Michigan

  1/1/18 → 12/31/23

  Project: Research project

  • retirement 100%
  • health 47%

• Health and Retirement Study Yrs 23-28

  Thyagarajan, B.

  University of Michigan

  1/1/15 → 12/31/17

  Project: Research project

  • retirement 100%
  • health 47%

• Hepatic Energy Fluxes, NASH, and Vertical Sleeve Gastrectomy

  Ikramuddin, S., Amin, K., Bolan, P. J., Chauhan, A., Connett, J. E., Crawford, P., Lake, J. R. & d'Avignon, D.

  NIH Natl Inst of Diabetes/Dig/Kidney Dis

  8/1/19 → 5/31/22

  Project: Research project

  • energy flux 100%

• High resolution mass spectrometric profile analysis of carcinogen-DNA adducts in oral cells of cigarette smokers and squamous cell carcinoma of the head and neck

  Hecht, S. S., Hatsukami, D. K., Khariwala, S. S. & Le, C. T.

  NIH NATIONAL CANCER INSTITUTE (NCI)

  9/21/21 → 8/31/26

  Project: Research project

• High School and Beyond Venous Blood Pilot Study

  Warren, R. & Thyagarajan, B.

  Alzheimer's Association

  1/1/20 → 6/30/21

  Project: Research project

• Hispanic Community Children's Health Study of Latino Youth

  Thyagarajan, B. & Eckfeldt, J. H.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  4/1/11 → 11/30/16

  Project: Research project

  • Child health 100%

• Hispanic Community Health Study Central Laboratory

  Thyagarajan, B.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  9/30/06 → 5/31/13

  Project: Research project

  • health 100%

• Hispanic Community Health Study - Study of Latinos

  Thyagarajan, B.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  3/1/18 → 3/31/19

  Project: Research project

  • health 100%

• Hispanic Community Health Study-Study of Latinos(HCHS-SO

  Thyagarajan, B. & Eckfeldt, J. H.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  6/1/14 → 4/30/18

  Project: Research project

  • Latinos 100%
  • Health 55%

• Hispanic Community Health Study- Study of Latinos (HCHS-SOL) V3. Tasks A,B,C

  Thyagarajan, B.

  THE UNIV. OF N. CAROLINA AT CHAPEL HILL

  11/30/18 → 11/29/24

  Project: Research project

  • health 100%