Institute for Therapeutics Discovery and Development

Organization profile

Organization profile

Institute for Therapeutics Discovery and Development (ITDD; Gunda I. Georg, Ph.D., Director, Vadim J. Gurvich, Ph.D., Associate Director) is a research center within the College of Pharmacy that would enable creating an almost complete line from drug discovery to drug development to clinical trials within the University of Minnesota. The Institute's purpose is to conduct research, provide education and offer scientific services to research and business communities in the area of drug discovery and development. The Institute greatly enhances the research capabilities of the University of Minnesota by allowing translation of the biological discoveries to new therapies and bringing drugs to market. The Institute consists of four scientific cores - Medicinal Chemistry, High-Throughput Screening, Lead and Probe Discovery, and Chemical Process Development. The Institute offers a variety of services including drug discovery, HTS and assay development (assay capabilities include absorbance, FRET, fluorescence, luminescence, cell based reporter & viability assays, FP, and high content image analysis assays), computational drug design, lead identification and optimization, medicinal chemistry, organic chemistry, chemical libraries development, chemical process development, scale up, API synthesis under cGMP conditions, CMC support for IND applications, protein purification, analytical services, and others.

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    Profiles

    No photo of Peter I Dosa

    Peter I Dosa

    Person: Academic Professional

    20122018

    Projects

    Functions of CD177 as a novel IgG Fc receptor

    Wu, J. & Hawkinson, J.

    NIH Nat'l Inst of Allergy & Infect Dis

    2/21/201/31/22

    Project: Research project

  • MASTER: CRO Support for NCATS Medicinal Chemistry for Lead Optimization

    Gurvich, V. J., Georg, G., Hawkinson, J., Walters, M. A. & Wong, H. L.

    NIHNIDA NATL INST ON DRUG AB

    9/26/199/25/24

    Project: Research project

  • Research Output

    A Curiously Linear Path to Academic Drug Discovery

    Nelson, K. M., Mar 12 2020, In : ACS Medicinal Chemistry Letters. 11, 3, p. 217-220 4 p.

    Research output: Contribution to journalReview article

  • Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor

    Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, Correia, C., Kaufmann, S. H., Weinshilboum, R. M. & Wang, L., Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • Press / Media

    UMN collaboration produces thousands of gallons hand sanitizer

    Vadim J Gurvich

    5/7/20

    1 item of Media coverage

    Press/Media: Expert Comment

    Are there benefits to eating turmeric and other spices?

    Kathryn Nelson

    4/6/20

    1 item of Media coverage

    Press/Media: Expert Comment