Projects per year
Organization profile
Organization profile
Institute for Therapeutics Discovery and Development (ITDD; Gunda I. Georg, Ph.D., Director, Vadim J. Gurvich, Ph.D., Associate Director) is a research center within the College of Pharmacy that would enable creating an almost complete line from drug discovery to drug development to clinical trials within the University of Minnesota. The Institute's purpose is to conduct research, provide education and offer scientific services to research and business communities in the area of drug discovery and development. The Institute greatly enhances the research capabilities of the University of Minnesota by allowing translation of the biological discoveries to new therapies and bringing drugs to market. The Institute consists of four scientific cores - Medicinal Chemistry, High-Throughput Screening, Lead and Probe Discovery, and Chemical Process Development. The Institute offers a variety of services including drug discovery, HTS and assay development (assay capabilities include absorbance, FRET, fluorescence, luminescence, cell based reporter & viability assays, FP, and high content image analysis assays), computational drug design, lead identification and optimization, medicinal chemistry, organic chemistry, chemical libraries development, chemical process development, scale up, API synthesis under cGMP conditions, CMC support for IND applications, protein purification, analytical services, and others.
Fingerprint
Collaborations and top research areas from the last five years
Profiles
-
Eyup Akgun
- Institute for Therapeutics Discovery and Development - Research Professional 6
Person: Researchers
-
Narsihmulu Cheryala
- Institute for Therapeutics Discovery and Development - Research Professional 7
Person: Researchers
-
Ravi Krishna Dada
- Institute for Therapeutics Discovery and Development - Research Professional 5
Person: Researchers
-
Slo3 inhibitors for non-hormonal male contraception
Georg, G. (PI) & Wong, H. L. (CoI)
2/15/25 → 1/31/27
Project: Research project
-
Synthesis of potential contraceptive agents
Georg, G. (PI) & Cheryala, N. (Other Role)
2/1/25 → 4/30/25
Project: Research project
-
Triptonide Prodrugs
Georg, G. (PI), Wong, H. L. (CoI), Jakkaraj, S. R. (Other Role), John, K. E. (Other Role) & Vantaddu, N. R. (Other Role)
12/15/24 → 5/31/25
Project: Research project
-
A linear approach for the total synthesis of sex pheromone (3S, 5R, 6S)-6-isopropyl-3,5-dimethyltetrahydro-2H-pyran-2-one and prelactone B
Surve, M., Gantasala, N., Pudi, S. & Pabbaraja, S., 2025, In: Synthetic Communications. 55, 4, p. 305-314 10 p.Research output: Contribution to journal › Article › peer-review
-
Challenges with effective removal of surfactants from monoclonal antibody formulations
Refaat, H., Ahmad, A., Kamel, E., Gurvich, V. J., Rathore, A. S., Suryanarayanan, R. & Nejadnik, R., Feb 10 2025, In: International journal of pharmaceutics. 670, 125146.Research output: Contribution to journal › Article › peer-review
-
Effect of formulation composition on trastuzumab stability
Ahmad, A., Refaat, H., Bhattacharya, S., Gurvich, V. J., Rathore, A. S., Nejadnik, R. & Suryanarayanan, R., Feb 25 2025, In: International journal of pharmaceutics. 671, 125275.Research output: Contribution to journal › Article › peer-review
Press/Media
-
UMN collaboration produces thousands of gallons hand sanitizer
Gurvich, V. J.
5/7/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
-
Are there benefits to eating turmeric and other spices?
Nelson, K.
4/6/20
1 item of Media coverage
Press/Media: Expert Comment or Interview