Projects per year
Organization profile
Organization profile
Institute for Therapeutics Discovery and Development (ITDD; Gunda I. Georg, Ph.D., Director, Vadim J. Gurvich, Ph.D., Associate Director) is a research center within the College of Pharmacy that would enable creating an almost complete line from drug discovery to drug development to clinical trials within the University of Minnesota. The Institute's purpose is to conduct research, provide education and offer scientific services to research and business communities in the area of drug discovery and development. The Institute greatly enhances the research capabilities of the University of Minnesota by allowing translation of the biological discoveries to new therapies and bringing drugs to market. The Institute consists of four scientific cores - Medicinal Chemistry, High-Throughput Screening, Lead and Probe Discovery, and Chemical Process Development. The Institute offers a variety of services including drug discovery, HTS and assay development (assay capabilities include absorbance, FRET, fluorescence, luminescence, cell based reporter & viability assays, FP, and high content image analysis assays), computational drug design, lead identification and optimization, medicinal chemistry, organic chemistry, chemical libraries development, chemical process development, scale up, API synthesis under cGMP conditions, CMC support for IND applications, protein purification, analytical services, and others.
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Profiles
Narsihmulu Cheryala
- Institute for Therapeutics Discovery and Development - Researcher
Person: Researcher
Matthew E Cuellar
- Institute for Therapeutics Discovery and Development - Researcher
Person: Researcher
Peter I Dosa
- Institute for Therapeutics Discovery and Development - Research Project Specialist
Person: Academic Professional
Projects
Functions of CD177 as a novel IgG Fc receptor
Wu, J. & Hawkinson, J.
NIH Nat'l Inst of Allergy & Infect Dis
2/21/20 → 1/31/22
Project: Research project
Support Services for synthesis of (-)-Phenserine Tartrate Clinical Grade Material
Gurvich, V. J.
9/30/19 → 9/29/20
Project: Research project
MASTER: CRO Support for NCATS Medicinal Chemistry for Lead Optimization
Gurvich, V. J., Georg, G., Hawkinson, J., Walters, M. A. & Wong, H. L.
9/26/19 → 9/25/24
Project: Research project
Research Output
A Curiously Linear Path to Academic Drug Discovery
Nelson, K. M., Mar 12 2020, In : ACS Medicinal Chemistry Letters. 11, 3, p. 217-220 4 p.Research output: Contribution to journal › Review article
Anastrozole has an association between degree of estrogen suppression and outcomes in early breast cancer and is a ligand for estrogen receptor
Ingle, J. N., Cairns, J., Suman, V. J., Shepherd, L. E., Fasching, P. A., Hoskin, T. L., Singh, R. J., Desta, Z., Kalari, K. R., Ellis, M. J., Goss, P. E., Chen, B. E., Volz, B., Barman, P., Carlson, E. E., Haddad, T., Goetz, M. P., Goodnature, B., Cuellar, M. E., Walters, M. A. & 4 others, , Jun 15 2020, In : Clinical Cancer Research. 26, 12, p. 2986-2996 11 p.Research output: Contribution to journal › Article
Open Access
Author Correction: A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals (Scientific Reports, (2020), 10, 1, (3869), 10.1038/s41598-020-60777-x)
Liu, P., Smith, B. R., Montonye, M. L., Kemper, L. J., Leinonen-Wright, K., Nelson, K. M., Higgins, L. A., Guerrero, C. R., Markowski, T. W., Zhao, X., Petersen, A. J., Knopman, D. S., Petersen, R. C. & Ashe, K. H., Dec 1 2020, In : Scientific reports. 10, 1, 8077.Research output: Contribution to journal › Comment/debate
Open Access
Press / Media
UMN collaboration produces thousands of gallons hand sanitizer
Vadim J Gurvich
5/7/20
1 item of Media coverage
Press/Media: Expert Comment
Are there benefits to eating turmeric and other spices?
4/6/20
1 item of Media coverage
Press/Media: Expert Comment