Organization profile

Organization profile

Disease-causing microorganisms that find their way into feeds and foods or farms and homes can pose a threat to the health of the animal and human hosts. The Host - Pathogen Interface research cluster seeks to uncover both the common and unique ways that micro-organisms act to gain entry and produce disease in their hosts, and understand how protective barriers and defense mechanisms in animal tissues and cells work to combat bacterial, viral, and parasitic infectious agents. Through their discoveries, our investigators develop innovative approaches to prevent or ameliorate outbreaks of infectious diseases in humans, companion animals, and livestock.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Lawsonia Bacteria Medicine & Life Sciences
Lawsonia intracellularis Agriculture & Biology
Swine Medicine & Life Sciences
Enteritis Medicine & Life Sciences
Influenza in Birds Medicine & Life Sciences
Orthomyxoviridae Medicine & Life Sciences
swine Agriculture & Biology
Viruses Medicine & Life Sciences

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Projects 1998 2022

Immunity
Lassa Fever
Lassa virus
Virulence
plasma protein Z

Research Output 1978 2018

6 Citations

Detection of HIV-1-specific gastrointestinal tissue resident CD8 + T-cells in chronic infection

Kiniry, B. E., Li, S., Ganesh, A., Hunt, P. W., Somsouk, M., Skinner, P. J., Deeks, S. G. & Shacklett, B. L., May 1 2018, In : Mucosal Immunology. 11, 3, p. 909-920 12 p.

Research output: Contribution to journalArticle

HIV-1
T-Lymphocytes
Infection
Phenotype
Mucous Membrane

Identification of conserved, primary sequence motifs that direct retrovirus RNA fate.

Singh, G., Rife, BD., Seufzer, B., Salemi, M., Rendahl, A. & Boris-Lawrie, K., May 26 2018, In : Nucleic Acids Research.

Research output: Contribution to journalArticle

Open Access
Conserved Sequence
Retroviridae
RNA
5' Untranslated Regions
HIV
3 Citations

Simian immunodeficiency virus (SIV)-specific chimeric antigen receptor-T cells engineered to target B cell follicles and suppress SIV replication

Haran, K. P., Hajduczki, A., Pampusch, M. S., Mwakalundwa, G., Vargas-Inchaustegui, D. A., Rakasz, E. G., Connick, E., Berger, E. A. & Skinner, P. J., Mar 20 2018, In : Frontiers in Immunology. 9, MAR, 492.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
Virus Replication
T-Cell Antigen Receptor
B-Lymphocytes
Antigen Receptors