Organization profile

Organization profile

Disease-causing microorganisms that find their way into feeds and foods or farms and homes can pose a threat to the health of the animal and human hosts. The Host - Pathogen Interface research cluster seeks to uncover both the common and unique ways that micro-organisms act to gain entry and produce disease in their hosts, and understand how protective barriers and defense mechanisms in animal tissues and cells work to combat bacterial, viral, and parasitic infectious agents. Through their discoveries, our investigators develop innovative approaches to prevent or ameliorate outbreaks of infectious diseases in humans, companion animals, and livestock.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Lawsonia Bacteria Medicine & Life Sciences
Lawsonia intracellularis Agriculture & Biology
Swine Medicine & Life Sciences
Enteritis Medicine & Life Sciences
Influenza in Birds Medicine & Life Sciences
Orthomyxoviridae Medicine & Life Sciences
swine Agriculture & Biology
digestive system diseases Agriculture & Biology

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Projects 1998 2022

Lassa Fever
Lassa virus
Virulence
plasma protein Z
poultry production
animal production
USDA

Research Output 1978 2019

Characterization of age-related susceptibility of macrophages to porcine reproductive and respiratory syndrome virus

Gray, D. K., Dvorak, C., Robinson, S. R. & Murtaugh, M. P., Apr 2 2019, In : Virus Research. 263, p. 139-144 6 p.

Research output: Contribution to journalArticle

Porcine respiratory and reproductive syndrome virus
Swine
Macrophages
Virus Diseases
Alveolar Macrophages

Identification of conserved, primary sequence motifs that direct retrovirus RNA fate

Singh, G., Rife, BD., Seufzer, B., Salemi, M., Rendahl, A. & Boris-Lawrie, K., Aug 21 2018, In : Nucleic Acids Research. 46, 14, p. 7366-7378 13 p.

Research output: Contribution to journalArticle

Open Access
Conserved Sequence
Retroviridae
RNA
HIV
T-Lymphocytes
9 Citations (Scopus)

A New Combination of a Pleuromutilin Derivative and Doxycycline for Treatment of Multidrug-Resistant Acinetobacter baumannii

Siricilla, S., Mitachi, K., Yang, J., Eslamimehr, S., Lemieux, M. R., Meibohm, B., Ji, Y. & Kurosu, M., Apr 13 2017, In : Journal of Medicinal Chemistry. 60, 7, p. 2869-2878 10 p.

Research output: Contribution to journalArticle

Acinetobacter baumannii
Doxycycline
Pharmaceutical Preparations
Colistin
Tobramycin