Projects per year
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where Genetics Mechanisms of Cancer is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Kate Adamala
- Genetics, Cell Biology and Development (CBS) - Associate Professor
- Genetics, Cell Biology and Development (TMED) - Associate Professor
- Genetics Mechanisms of Cancer
Person: Member, Faculty, Medical School Affiliates
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Hideki Aihara
- Chemical and Structural Biology (BMBB) - Professor
- Chemical and Structural Biology (TMED) - Leader
- Biochemistry, Molecular Biology, and Biophysics (TMED) - Associate Professor
- Institute for Molecular Virology
- Genetics Mechanisms of Cancer
Person: Member, Faculty, Medical School Affiliates
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Constantin Aliferis, MD, PhD
- Institute for Health Informatics - Professor
- Office of Academic Clinical Affairs
- Genetics Mechanisms of Cancer
Person: Member, Faculty
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Allogeneic, multiplex base edited, dual-targeted gamma delta CAR-T cell development for metastatic castration-resistant prostate cancer
Moriarity, B. S. (PI) & Webber, B. R. (CoI)
9/30/24 → 9/29/27
Project: Research project
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Development of a novel therapeutic for metastatic colorectal cancer
LaRocca, C. (PI)
9/1/24 → 8/31/26
Project: Research project
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Structural analysis of poliovirus and antibodies
Hafenstein, S. (PI) & Waddey, B. T. (Graduate Student)
PATH, BILL & MELINDA GATES FOUNDATION
8/8/24 → 4/30/25
Project: Research project
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Cell Type Specific Suppression of Hyper-Recombination by Human RAD18 Is Linked to Proliferating Cell Nuclear Antigen K164 Ubiquitination
Rogers, C. B., Leung, W., Baxley, R. M., Kram, R. E., Wang, L., Buytendorp, J. P., Le, K., Largaespada, D. A., Hendrickson, E. A. & Bielinsky, A. K., Jan 2025, In: Biomolecules. 15, 1, 150.Research output: Contribution to journal › Article › peer-review
Open Access -
A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells
Schmit, M. M., Baxley, R. M., Wang, L., Hinderlie, P., Kaufman, M., Simon, E., Raju, A., Miller, J. S. & Bielinsky, A. K., Jan 24 2024, In: Open biology. 14, 1, 230407.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Advancing gene targeting for primary immune deficiencies: Adenine base editing of the human IL2RG locus for correction of SCID-X1
McIvor, R. S., Eaton, E. J., Webber, B. R. & Moriarity, B. S., Jun 5 2024, In: Molecular Therapy. 32, 6, p. 1606-1608 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Datasets
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AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice
Chauhan, M., Daugherty, A. L., Khadir, F., Duzenli, O. F., Hoffman, A., Tinklenberg, J. A., Kang, P. B., Aslanidi, G. & Pacak, C. A., figshare, 2024
DOI: 10.6084/m9.figshare.c.7436190, https://springernature.figshare.com/collections/AAV-DJ_is_superior_to_AAV9_for_targeting_brain_and_spinal_cord_and_de-targeting_liver_across_multiple_delivery_routes_in_mice/7436190
Dataset
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AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice
Chauhan, M., Daugherty, A. L., Khadir, F., Duzenli, O. F., Hoffman, A., Tinklenberg, J. A., Kang, P. B., Aslanidi, G. & Pacak, C. A., figshare, 2024
DOI: 10.6084/m9.figshare.c.7436190.v1, https://springernature.figshare.com/collections/AAV-DJ_is_superior_to_AAV9_for_targeting_brain_and_spinal_cord_and_de-targeting_liver_across_multiple_delivery_routes_in_mice/7436190/1
Dataset
Press/Media
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Interviewed by Oncology Tube regarding our latest work on developing a new computational model to predict drug combination efficacy in patients
1/5/21
1 Media contribution
Press/Media: Research
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Cancer-fighting firm based on U of M research raises $42 million
11/23/20
1 item of Media coverage
Press/Media: Expert Comment or Interview
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Charles Darwin’s hunch about early life was probably right
11/11/20
1 item of Media coverage
Press/Media: Expert Comment or Interview