Experimental and Clinical Pharmacology

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Review article
2020

GBA1 mutations: Prospects for exosomal biomarkers in α-synuclein pathologies

Johnson, P. H., Weinreb, N. J., Cloyd, J. C., Tuite, P. J. & Kartha, R. V., Feb 2020, In : Molecular Genetics and Metabolism. 129, 2, p. 35-46 12 p.

Research output: Contribution to journalReview article

Gene-based dose optimization in children

Ramsey, L. B., Brown, J. T., Vear, S. I., Bishop, J. R. & Van Driest, S. L., Jan 6 2020, In : Annual review of pharmacology and toxicology. 60, p. 311-331 21 p.

Research output: Contribution to journalReview article

1 Scopus citations

Review: Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)

Pastick, K. A., Okafor, E. C., Wang, F., Lofgren, S. M., Skipper, C. P., Nicol, M. R., Pullen, M. F., Rajasingham, R., McDonald, E. G., Lee, T. C., Schwartz, I. S., Kelly, L. E., Lother, S. A., Mitjà, O., Letang, E., Abassi, M. & Boulware, D. R., Mar 16 2020, In : Open Forum Infectious Diseases. 7, 4, ofaa130.

Research output: Contribution to journalReview article

Open Access

Tolerance to antibiotics affects response

Berti, A. D. & Hirsch, E. B., Jan 10 2020, In : Science. 367, 6474, p. 141-142 2 p.

Research output: Contribution to journalReview article

1 Scopus citations
2019

A systematic review of genome-wide association studies of antipsychotic response

Allen, J. D. & Bishop, J. R., Mar 2019, In : Pharmacogenomics. 20, 4, p. 291-306 16 p.

Research output: Contribution to journalReview article

2 Scopus citations

Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy

Brown, J. T., Bishop, J. R., Sangkuhl, K., Nurmi, E. L., Mueller, D. J., Dinh, JC., Gaedigk, A., Klein, T. E., Caudle, K. E., McCracken, J. T., de Leon, J. & Leeder, J. S., Jul 2019, In : Clinical pharmacology and therapeutics. 106, 1, p. 94-102 9 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study

EpiBioS4Rx Study Group Investigators, Mar 2019, In : Neurobiology of Disease. 123, p. 115-121 7 p.

Research output: Contribution to journalReview article

Open Access
7 Scopus citations

Leveraging the cardio-protective and anticancer properties of resveratrol in cardio-oncology

Abdelgawad, I. Y., Grant, M. K. O. & Zordoky, B. N., Mar 2019, In : Nutrients. 11, 3, 627.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Orphan drug development: the increasing role of clinical pharmacology

Ahmed, M. A., Okour, M., Brundage, R. & Kartha, R. V., Oct 1 2019, In : Journal of Pharmacokinetics and Pharmacodynamics. 46, 5, p. 395-409 15 p.

Research output: Contribution to journalReview article

3 Scopus citations

Peripheral versus central nervous system APOE in Alzheimer's disease: Interplay across the blood-brain barrier

Chernick, D., Ortiz-Valle, S., Jeong, A., Qu, W. & Li, L., Aug 24 2019, In : Neuroscience Letters. 708, 134306.

Research output: Contribution to journalReview article

4 Scopus citations

Pharmacogenetics of treating pediatric anxiety and depression

Ramsey, L. B., Bishop, J. R. & Strawn, J. R., Aug 27 2019, In : Pharmacogenomics. 20, 12, p. 867-870 4 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Review of Real-World Implementation Data on Emtricitabine-Tenofovir Disoproxil Fumarate as HIV Pre-exposure Prophylaxis in the United States

Adams, J. L., Shelley, K. & Nicol, M. R., Apr 2019, In : Pharmacotherapy. 39, 4, p. 486-500 15 p.

Research output: Contribution to journalReview article

3 Scopus citations

The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol

For the EpiBioS4Rx Study Group, Mar 2019, In : Neurobiology of Disease. 123, p. 110-114 5 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations
2018

Clinical and preclinical evidence of sex-related differences in anthracycline-induced cardiotoxicity

Meiners, B., Shenoy, C. & Zordoky, B. N., Aug 29 2018, In : Biology of Sex Differences. 9, 1, 38.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations
3 Scopus citations

Genetic analysis of deep phenotyping projects in common disorders

Gershon, E. S., Pearlson, G., Keshavan, M. S., Tamminga, C., Clementz, B., Buckley, P. F., Alliey-Rodriguez, N., Liu, C., Sweeney, J. A., Keedy, S., Meda, S. A., Tandon, N., Shafee, R., Bishop, J. R. & Ivleva, E. I., May 2018, In : Schizophrenia Research. 195, p. 51-57 7 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Genetics of acute rejection after kidney transplantation

Dorr, C. R., Oetting, W. S., Jacobson, P. A. & Israni, A. K., Mar 2018, In : Transplant International. 31, 3, p. 263-277 15 p.

Research output: Contribution to journalReview article

Open Access
8 Scopus citations

Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer’s disease

Jeong, A., Suazo, K. F., Wood, W. G., Distefano, M. D. & Li, L., May 4 2018, In : Critical Reviews in Biochemistry and Molecular Biology. 53, 3, p. 279-310 32 p.

Research output: Contribution to journalReview article

Open Access
12 Scopus citations

More than fishing for a cure: The promises and pitfalls of high throughput cancer cell line screens

Ling, A., Gruener, R. F., Fessler, J. & Huang, R. S., Nov 2018, In : Pharmacology and Therapeutics. 191, p. 178-189 12 p.

Research output: Contribution to journalReview article

1 Scopus citations

Pharmacology of Antiretrovirals in the Female Genital Tract for HIV Prevention

Nicol, M. R., Corbino, J. A. & Cottrell, M. L., Nov 2018, In : Journal of Clinical Pharmacology. 58, 11, p. 1381-1395 15 p.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2017

Anatomy and roles of lymphatics in inflammatory diseases

Al-Kofahi, M., Yun, J. W., Minagar, A. & Alexander, J. S., Aug 2017, In : Clinical and Experimental Neuroimmunology. 8, 3, p. 199-214 16 p.

Research output: Contribution to journalReview article

Open Access
4 Scopus citations

Modeling Enterohepatic Circulation

Okour, M. & Brundage, R. C., Oct 1 2017, In : Current Pharmacology Reports. 3, 5, p. 301-313 13 p.

Research output: Contribution to journalReview article

3 Scopus citations

Pharmacogenetics and Pharmacogenomics of Targeted Therapeutics in Chronic Myeloid Leukemia

Nath, A., Wang, J. & Stephanie Huang, R., Dec 1 2017, In : Molecular Diagnosis and Therapy. 21, 6, p. 621-631 11 p.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations

Pharmacogenomics of autism spectrum disorder

Brown, J. T., Eum, S., Cook, E. H. & Bishop, J. R., Mar 2017, In : Pharmacogenomics. 18, 4, p. 403-414 12 p.

Research output: Contribution to journalReview article

2 Scopus citations

Predictors of liver transplant patient survival: A critical review using a holistic framework

Pruinelli, L., Monsen, K. A., Gross, C. R., Radosevich, D. M., Simon, G. J. & Westra, B. L., Jan 1 2017, In : Progress in Transplantation. 27, 1, p. 98-106 9 p.

Research output: Contribution to journalReview article

2 Scopus citations

Team science as interprofessional collaborative research practice: A systematic review of the science of team science literature

Little, M. M., St Hill, C. A., Ware, K. B., Swanoski, M. T., Chapman, S. A., Lutfiyya, M. N. & Cerra, F. B., Jan 2017, In : Journal of Investigative Medicine. 65, 1, p. 15-22 8 p.

Research output: Contribution to journalReview article

Open Access
13 Scopus citations

The impact of exposure to antidepressant medications during pregnancy on neonatal outcomes: a review of retrospective database cohort studies

Tak, C. R., Job, K. M., Schoen-Gentry, K., Campbell, S. C., Carroll, P., Costantine, M., Brixner, D., Birnbaum, A. K. & Sherwin, C. M. T., Sep 1 2017, In : European Journal of Clinical Pharmacology. 73, 9, p. 1055-1069 15 p.

Research output: Contribution to journalReview article

8 Scopus citations
36 Scopus citations
2016

A review of intranasal formulations for the treatment of seizure emergencies

Kapoor, M., Cloyd, J. C. & Siegel, R. A., Sep 10 2016, In : Journal of Controlled Release. 237, p. 147-159 13 p.

Research output: Contribution to journalReview article

42 Scopus citations

Autoantibodies in Alzheimer's disease: Potential biomarkers, pathogenic roles, and therapeutic implications

Wu, J. & Li, L., Jan 1 2016, In : Journal of Biomedical Research. 30, 5, p. 361-372 12 p.

Research output: Contribution to journalReview article

Open Access
26 Scopus citations

Critical evaluation of ceftolozane–tazobactam for complicated urinary tract and intra-abdominal infections

Giancola, S. E., Mahoney, M. V., Bias, T. E. & Hirsch, E. B., May 19 2016, In : Therapeutics and Clinical Risk Management. 12, p. 787-797 11 p.

Research output: Contribution to journalReview article

Open Access
12 Scopus citations
2015

Atomoxetine pharmacogenetics: Associations with pharmacokinetics, treatment response and tolerability

Brown, J. T. & Bishop, J. R., Aug 1 2015, In : Pharmacogenomics. 16, 13, p. 1513-1520 8 p.

Research output: Contribution to journalReview article

7 Scopus citations
82 Scopus citations

Cell penetrating peptide conjugated chitosan for enhanced delivery of nucleic acid

Layek, B., Lipp, L. & Singh, J., Dec 4 2015, In : International journal of molecular sciences. 16, 12, p. 28912-28930 19 p.

Research output: Contribution to journalReview article

35 Scopus citations

Intramuscular and rectal therapies of acute seizures

Leppik, I. E. & Patel, S. I., Aug 1 2015, In : Epilepsy and Behavior. 49, p. 307-312 6 p.

Research output: Contribution to journalReview article

10 Scopus citations

Intravenous and Intramuscular Formulations of Antiseizure Drugs in the Treatment of Epilepsy

Patel, S. I., Birnbaum, A. K., Cloyd, J. C. & Leppik, I. E., Dec 1 2015, In : CNS Drugs. 29, 12, p. 1009-1022 14 p.

Research output: Contribution to journalReview article

8 Scopus citations

Optimizing drug therapy in pediatric SCT: Focus on pharmacokinetics

McCune, J. S., Jacobson, P., Wiseman, A. & Militano, O., Feb 7 2015, In : Bone marrow transplantation. 50, 2, p. 165-172 8 p.

Research output: Contribution to journalReview article

7 Scopus citations

Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

Zordoky, B. N. M., Robertson, I. M. & Dyck, J. R. B., Jun 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 6, p. 1155-1177 23 p.

Research output: Contribution to journalReview article

150 Scopus citations

Research fellowship programs as a pathway for training independent clinical pharmacy scientists

Mueller, E. W., Bishop, J. R., Kanaan, A. O., Kiser, T. H., Phan, H. & Yang, K. Y., Mar 1 2015, In : Pharmacotherapy. 35, 3, p. e13-e19

Research output: Contribution to journalReview article

6 Scopus citations

Third International Congress on Epilepsy, Brain and Mind: Part 1

Korczyn, A. D., Schachter, S. C., Amlerova, J., Bialer, M., van Emde Boas, W., Brázdil, M., Brodtkorb, E., Engel, J., Gotman, J., Komárek, V., Leppik, I. E., Marusic, P., Meletti, S., Metternich, B., Moulin, C. J. A., Muhlert, N., Mula, M., Nakken, K. O., Picard, F., Schulze-Bonhage, A. & 4 others, Theodore, W., Wolf, P., Zeman, A. & Rektor, I., Sep 1 2015, In : Epilepsy and Behavior. 50, p. 116-137 22 p.

Research output: Contribution to journalReview article

9 Scopus citations
2014

Cholesterol as a causative factor in Alzheimer's disease: A debatable hypothesis

Wood, W. G., Li, L., Müller, W. E. & Eckert, G. P., May 2014, In : Journal of Neurochemistry. 129, 4, p. 559-572 14 p.

Research output: Contribution to journalReview article

97 Scopus citations

Competing endogenous RNAs (ceRNAs): New entrants to the intricacies of gene regulation

Kartha, R. V. & Subramanian, S., Jan 1 2014, In : Frontiers in Genetics. 5, JAN, Article 8.

Research output: Contribution to journalReview article

166 Scopus citations

Genetic determinants of selective serotonin reuptake inhibitor related sexual dysfunction

Stevenson, J. M. & Bishop, J. R., Nov 1 2014, In : Pharmacogenomics. 15, 14, p. 1791-1806 16 p.

Research output: Contribution to journalReview article

4 Scopus citations

HDL and cognition in neurodegenerative disorders

Hottman, D. A., Chernick, D., Cheng, S., Wang, Z. & Li, L., Dec 1 2014, In : Neurobiology of Disease. 72, Part A, p. 22-36 15 p.

Research output: Contribution to journalReview article

54 Scopus citations

Lymphatic dysregulation in intestinal inflammation: New insights into inflammatory bowel disease pathomechanisms

Becker, F., Yi, P., Al-Kofahi, M., Ganta, V. C., Morris, J. & Alexander, J. S., Mar 2014, In : Lymphology. 47, 1, p. 3-27 25 p.

Research output: Contribution to journalReview article

22 Scopus citations

Outcome measures of behavioral weight loss programs in perimenopause

Zargarian, N., Lindquist, R., Gross, C. R. & Treat-Jacobson, D., Jan 1 2014, In : Southern Medical Journal. 107, 8, p. 486-496 11 p.

Research output: Contribution to journalReview article

Protein Prenylation and Synaptic Plasticity: Implications for Alzheimer’s Disease

Hottman, D. A. & Li, L., Oct 2 2014, In : Molecular neurobiology. 50, 1, p. 177-185 9 p.

Research output: Contribution to journalReview article

27 Scopus citations
2013

Circulating microRNAs as biomarkers for inflammatory diseases

Mi, S., Zhang, J., Zhang, W. & Huang, R. S., Jan 1 2013, In : MicroRNA (Shāriqah, United Arab Emirates). 2, 1, p. 63-71 9 p.

Research output: Contribution to journalReview article

44 Scopus citations

Epilepsy, behavior, and art (Epilepsy, Brain, and Mind, part 1)

Rektor, I., Schachter, S. C., Arzy, S., Baloyannis, S. J., Bazil, C., Brázdil, M., Engel, J., Helmstaedter, G., Hesdorffer, D. C., Jones-Gotman, M., Kesner, L., Komárek, V., Krämer, G., Leppik, I. E., Mann, M. W., Mula, M., Risse, G. L., Stoker, G. W., Kasteleijn- Nolst Trenité, D. G. A., Trimble, M. & 2 others, Tyrliková, I. & Korczyn, A. D., Aug 1 2013, In : Epilepsy and Behavior. 28, 2, p. 261-282 22 p.

Research output: Contribution to journalReview article

12 Scopus citations

Extended-release antiepileptic drugs: A comparison of pharmacokinetic parameters relative to original immediate-release formulations

Leppik, I. E. & Hovinga, C. A., Jan 1 2013, In : Epilepsia. 54, 1, p. 28-35 8 p.

Research output: Contribution to journalReview article

34 Scopus citations