Experimental and Clinical Pharmacology

2023

Angiotensin-Converting Enzyme 2 Expression and Severity of SARS-CoV-2 Infection

Alabsi, S., Dhole, A., Hozayen, S. & Chapman, S. A., Mar 2023, In: Microorganisms. 11, 3, 612.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

N-acetylcysteine Pharmacology and Applications in Rare Diseases—Repurposing an Old Antioxidant

Sahasrabudhe, S. A., Terluk, M. R. & Kartha, R. V., Jul 2023, In: Antioxidants. 12, 7, 1316.

Research output: Contribution to journal › Review article › peer-review

Open Access

Personalizing prevention: Advances in pharmacotherapy for HIV prevention

Brizzi, M., Sherman, E. M., Green, S. B., Nowicki, D. N., Drwiega, E. N., Nicol, M. R., Chastain, D. B., Sahloff, E. G., Truong, W. R., Cluck, D., Badowski, M. E., Michienzi, S. M. & Durham, S. H., Apr 2023, In: Pharmacotherapy. 43, 4, p. 305-320 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Pharmacological treatment for older adults with epilepsy and comorbid neurodegenerative disorders

O'Dwyer, R., Foster, E., Leppik, I. & Kwan, P., Apr 1 2023, In: Current Opinion in Neurology. 36, 2, p. 117-123 7 p.

Research output: Contribution to journal › Review article › peer-review

PharmVar GeneFocus: SLCO1B1

Ramsey, L. B., Gong, L., Lee, S. B., Wagner, J. B., Zhou, X., Sangkuhl, K., Adams, S. M., Straka, R. J., Empey, P. E., Boone, E. C., Klein, T. E., Niemi, M. & Gaedigk, A., Apr 2023, In: Clinical pharmacology and therapeutics. 113, 4, p. 782-793 12 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Why ketamine

Coles, L., Rosenthal, E. S., Bleck, T. P., Elm, J., Zehtabchi, S., Chamberlain, J., Cloyd, J., Shinnar, S., Silbergleit, R. & Kapur, J., Apr 2023, In: Epilepsy and Behavior. 141, 109066.

Research output: Contribution to journal › Review article › peer-review

2022

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Heidenreich, P. A., Bozkurt, B., Aguilar, D., Allen, L. A., Byun, J. J., Colvin, M. M., Deswal, A., Drazner, M. H., Dunlay, S. M., Evers, L. R., Fang, J. C., Fedson, S. E., Fonarow, G. C., Hayek, S. S., Hernandez, A. F., Khazanie, P., Kittleson, M. M., Lee, C. S., Link, M. S., Milano, C. A., & 6 othersNnacheta, L. C., Sandhu, A. T., Stevenson, L. W., Vardeny, O., Vest, A. R. & Yancy, C. W., May 3 2022, In: Circulation. 145, 18, p. E895-E1032

Research output: Contribution to journal › Review article › peer-review

Open Access

855 Scopus citations

A Scoping Review of Attitudes and Experiences with Pharmacogenomic Testing among Patients and the General Public: Implications for Patient Counseling

Allen, J. D., Pittenger, A. L. & Bishop, J. R., Mar 2022, In: Journal of Personalized Medicine. 12, 3, 425.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

Building cross-border collaborations to increase diversity and accelerate rare disease drug development – meeting report from the inaugural IndoUSrare Annual Conference 2021

Khera, H. K., Venugopal, N., Karur, R. T., Mishra, R., Kartha, R. V. & Rajasimha, H. K., Jan 1 2022, In: Therapeutic Advances in Rare Disease. 3

Research output: Contribution to journal › Review article › peer-review

Open Access

Considering medication exposure in genomic association studies of cognition in psychotic disorders

Eum, S., Hill, S. K. & Bishop, J. R., Sep 1 2022, In: Pharmacogenomics. 23, 14, p. 791-806 16 p.

Research output: Contribution to journal › Review article › peer-review

Differences in Fosfomycin Resistance Mechanisms between Pseudomonas aeruginosa and Enterobacterales

Zheng, D., Bergen, P. J., Landersdorfer, C. B. & Hirsch, E. B., Feb 2022, In: Antimicrobial agents and chemotherapy. 66, 2, e01446-21.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Gaucher disease – more than just a rare lipid storage disease

Roh, J., Subramanian, S., Weinreb, N. J. & Kartha, R. V., Apr 2022, In: Journal of Molecular Medicine. 100, 4, p. 499-518 20 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Management of Anti-Seizure Medications during Pregnancy: Advancements in The Past Decade

Avachat, C., Barry, J. M., Lyu, X., Sherwin, C. M. & Birnbaum, A. K., Dec 2022, In: Pharmaceutics. 14, 12, 2733.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Sex dimorphism in response to targeted therapy and immunotherapy in non-small cell lung cancer patients: a narrative review

Huang, Y., Cho, H. J., Stranger, B. E. & Huang, R. S., May 2022, In: Translational Lung Cancer Research. 11, 5, p. 920-934 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Translational and clinical pharmacology considerations in drug repurposing for X-linked adrenoleukodystrophy—A rare peroxisomal disorder

Tieu, J. H., Sahasrabudhe, S. A., Orchard, P. J., Cloyd, J. C. & Kartha, R. V., Jun 2022, In: British Journal of Clinical Pharmacology. 88, 6, p. 2552-2563 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Translational Models to Predict Target Concentrations for Pre-Exposure Prophylaxis in Women

Lantz, A. M. & Nicol, M. R., Dec 1 2022, In: AIDS Research and Human Retroviruses. 38, 12, p. 909-923 15 p.

Research output: Contribution to journal › Review article › peer-review

2021

Current strategies for predicting side effects from second generation antipsychotics in youth

Brown, J. T., Campo-Soria, C. & Bishop, J. R., Jun 2021, In: Expert Opinion on Drug Metabolism and Toxicology. 17, 6, p. 655-664 10 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities

Cheff, D. M., Muotri, A. R., Stockwell, B. R., Schmidt, E. E., Ran, Q., Kartha, R. V., Johnson, S. C., Mittal, P., Arnér, E. S. J., Wigby, K. M., Hall, M. D. & Ramesh, S. K., Dec 2021, In: Orphanet Journal of Rare Diseases. 16, 1, 446.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Early detection of SARS-CoV-2 and other infections in solid organ transplant recipients and household members using wearable devices

Keating, B. J., Mukhtar, E. H., Elftmann, E. D., Eweje, F. R., Gao, H., Ibrahim, L. I., Kathawate, R. G., Lee, A. C., Li, E. H., Moore, K. A., Nair, N., Chaluvadi, V., Reason, J., Zanoni, F., Honkala, A. T., Al-Ali, A. K., Abdullah Alrubaish, F., Ahmad Al-Mozaini, M., Al-Muhanna, F. A., Al-Romaih, K., & 25 othersGoldfarb, S. B., Kellogg, R., Kiryluk, K., Kizilbash, S. J., Kohut, T. J., Kumar, J., O'Connor, M. J., Rand, E. B., Redfield, R. R., Rolnik, B., Rossano, J., Sanchez, P. G., Alavi, A., Bahmani, A., Bogu, G. K., Brooks, A. W., Metwally, A. A., Mishra, T., Marks, S. D., Montgomery, R. A., Fishman, J. A., Amaral, S., Jacobson, P. A., Wang, M. & Snyder, M. P., Jun 2021, In: Transplant International. 34, 6, p. 1019-1031 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

Gout prevalence in the Hmong: A prime example of health disparity and the role of community-based genetic research

Roman, Y. M., Lor, K., Xiong, T., Culhane-Pera, K. A. & Straka, R. J., May 2021, In: Personalized Medicine. 18, 3, p. 311-327 17 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Microglial TREM2 at the Intersection of Brain Aging and Alzheimer’s Disease

Qu, W. & Li, L., Sep 2 2021, In: Neuroscientist. 29, 3, p. 302-316 15 p.

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Serotonin transporter genetic variation and antidepressant response and tolerability: A systematic review and meta-analysis

Stein, K., Al Maruf, A., Müller, D. J., Bishop, J. R. & Bousman, C. A., Dec 2021, In: Journal of Personalized Medicine. 11, 12, 1334.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

2020

A systematic review of treatment and outcomes of pregnant women with COVID-19-A call for clinical trials

Pastick, K., Nicol, M. R., Smyth, E., Zash, R., Boulware, D. R., Rajasingham, R. & McDonald, E. G., Sep 1 2020, In: Open Forum Infectious Diseases. 7, 9

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Scopus citations

Biotyping in psychosis: using multiple computational approaches with one data set

Tamminga, C. A., Clementz, B. A., Pearlson, G., Keshavan, M., Gershon, E. S., Ivleva, E. I., McDowell, J., Meda, S. A., Keedy, S., Calhoun, V. D., Lizano, P., Bishop, J. R., Hudgens-Haney, M., Alliey-Rodriguez, N., Asif, H. & Gibbons, R., Sep 26 2020, In: Neuropsychopharmacology. 46, 1, p. 143-155 13 p.

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

CYP1B1 as a therapeutic target in cardio-oncology

Carrera, A. N., Grant, M. K. O. & Zordoky, B. N., Nov 2020, In: Clinical science. 134, 21, p. 2897-2927 31 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Scopus citations

Executive summary: Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review of the american society of health-system pharmacists, the infectious diseases society of america, the pediatric infectious diseases society, and the society of infectious diseases pharmacists

Rybak, M. J., Le, J., Lodise, T., Levine, D., Bradley, J., Liu, C., Mueller, B., Pai, M., Wong-Beringer, A., Rotschafer, J. C., Rodvold, K., Maples, H. D. & Lomaestro, B. M., 2020, In: Journal of the Pediatric Infectious Diseases Society. 9, 3, p. 281-284 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

GBA1 mutations: Prospects for exosomal biomarkers in α-synuclein pathologies

Johnson, P. H., Weinreb, N. J., Cloyd, J. C., Tuite, P. J. & Kartha, R. V., Feb 2020, In: Molecular Genetics and Metabolism. 129, 2, p. 35-46 12 p.

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Gene-based dose optimization in children

Ramsey, L. B., Brown, J. T., Vear, S. I., Bishop, J. R. & Van Driest, S. L., Jan 6 2020, In: Annual review of pharmacology and toxicology. 60, p. 311-331 21 p.

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence

Abdelgawad, I. Y., Sadak, K. T., Lone, D. W., Dabour, M. S., Niedernhofer, L. J. & Zordoky, B. N., Dec 1 2020, (E-pub ahead of print) In: Pharmacology and Therapeutics. 221, p. 107751

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Pharmacogenomics: an Update for Child and Adolescent Psychiatry

Namerow, L. B., Walker, S. A., Loftus, M., Bishop, J. R., Ruaño, G. & Malik, S., May 6 2020, In: Current psychiatry reports. 22, 5, 26.

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Pharmacogenomics of COVID-19 therapies

Takahashi, T., Luzum, J. A., Nicol, M. R. & Jacobson, P. A., Dec 1 2020, In: npj Genomic Medicine. 5, 1, 35.

Research output: Contribution to journal › Review article › peer-review

Open Access

53 Scopus citations

Pharmacokinetics and Pharmacological Properties of Chloroquine and Hydroxychloroquine in the Context of COVID-19 Infection

Nicol, M. R., Joshi, A., Rizk, M. L., Sabato, P. E., Savic, R. M., Wesche, D., Zheng, J. H. & Cook, J., Dec 2020, In: Clinical pharmacology and therapeutics. 108, 6, p. 1135-1149 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Scopus citations

Review: Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)

Pastick, K. A., Okafor, E. C., Wang, F., Lofgren, S. M., Skipper, C. P., Nicol, M. R., Pullen, M. F., Rajasingham, R., McDonald, E. G., Lee, T. C., Schwartz, I. S., Kelly, L. E., Lother, S. A., Mitjà, O., Letang, E., Abassi, M. & Boulware, D. R., Mar 16 2020, In: Open Forum Infectious Diseases. 7, 4, ofaa130.

Research output: Contribution to journal › Review article › peer-review

Open Access

142 Scopus citations

Review and Consensus on Pharmacogenomic Testing in Psychiatry

Bousman, C. A., Bengesser, S. A., Aitchison, K. J., Amare, A. T., Aschauer, H., Baune, B. T., Asl, B. B., Bishop, J. R., Burmeister, M., Chaumette, B., Chen, L. S., Cordner, Z. A., Deckert, J., Degenhardt, F., Delisi, L. E., Folkersen, L., Kennedy, J. L., Klein, T. E., McClay, J. L., McMahon, F. J., & 11 othersMusil, R., Saccone, N. L., Sangkuhl, K., Stowe, R. M., Tan, E. C., Tiwari, A. K., Zai, C. C., Zai, G., Zhang, J., Gaedigk, A. & Müller, D. J., Nov 4 2020, In: Pharmacopsychiatry. 54, 1, p. 5-17 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

70 Scopus citations

Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Rybak, M. J., Le, J., Lodise, T. P., Levine, D. P., Bradley, J. S., Liu, C., Mueller, B. A., Pai, M. P., Wong-Beringer, A., Rotschafer, J. C., Rodvold, K. A., Maples, H. D. & Lomaestro, B. M., May 18 2020, In: American Journal of Health-System Pharmacy. 77, 11, p. 835-863 29 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

524 Scopus citations

The role of HDL and HDL mimetic peptides as potential therapeutics for alzheimer’s disease

Chernick, D., Zhong, R. & Li, L., Sep 2020, In: Biomolecules. 10, 9, p. 1-28 28 p., 1276.

Research output: Contribution to journal › Review article › peer-review

Open Access

14 Scopus citations

Tolerance to antibiotics affects response

Berti, A. D. & Hirsch, E. B., Jan 10 2020, In: Science. 367, 6474, p. 141-142 2 p.

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

2019

A systematic review of genome-wide association studies of antipsychotic response

Allen, J. D. & Bishop, J. R., Mar 2019, In: Pharmacogenomics. 20, 4, p. 291-306 16 p.

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy

Brown, J. T., Bishop, J. R., Sangkuhl, K., Nurmi, E. L., Mueller, D. J., Dinh, JC., Gaedigk, A., Klein, T. E., Caudle, K. E., McCracken, J. T., de Leon, J. & Leeder, J. S., Jul 2019, In: Clinical pharmacology and therapeutics. 106, 1, p. 94-102 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

103 Scopus citations

Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study

EpiBioS4Rx Study Group Investigators, Mar 2019, In: Neurobiology of Disease. 123, p. 115-121 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

67 Scopus citations

Leveraging the cardio-protective and anticancer properties of resveratrol in cardio-oncology

Abdelgawad, I. Y., Grant, M. K. O. & Zordoky, B. N., Mar 2019, In: Nutrients. 11, 3, 627.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Scopus citations

Orphan drug development: the increasing role of clinical pharmacology

Ahmed, M. A., Okour, M., Brundage, R. & Kartha, R. V., Oct 1 2019, In: Journal of Pharmacokinetics and Pharmacodynamics. 46, 5, p. 395-409 15 p.

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Peripheral versus central nervous system APOE in Alzheimer's disease: Interplay across the blood-brain barrier

Chernick, D., Ortiz-Valle, S., Jeong, A., Qu, W. & Li, L., Aug 24 2019, In: Neuroscience Letters. 708, 134306.

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Pharmacogenetics of treating pediatric anxiety and depression

Ramsey, L. B., Bishop, J. R. & Strawn, J. R., Aug 27 2019, In: Pharmacogenomics. 20, 12, p. 867-870 4 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Precision medicine in adult and pediatric obesity: a clinical perspective

Bomberg, E. M., Ryder, J. R., Brundage, R. C., Straka, R. J., Fox, C. K., Gross, A. C., Oberle, M. M., Bramante, C. T., Sibley, S. D. & Kelly, A. S., Jan 1 2019, In: Therapeutic Advances in Endocrinology and Metabolism. 10

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Scopus citations

Review of Real-World Implementation Data on Emtricitabine-Tenofovir Disoproxil Fumarate as HIV Pre-exposure Prophylaxis in the United States

Adams, J. L., Shelley, K. & Nicol, M. R., Apr 2019, In: Pharmacotherapy. 39, 4, p. 486-500 15 p.

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol

For the EpiBioS4Rx Study Group, Mar 2019, In: Neurobiology of Disease. 123, p. 110-114 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Scopus citations

Where’s Waldo? Extrahepatic Site Options for Islet Transplantation

Coughlan, A. J., McEachron, K. R., Skube, M. E., Muratore, S., Bellin, M. D. & Beilman, G. J., 2019, In: OBM Transplantation. 3, 1

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

2018

Clinical and preclinical evidence of sex-related differences in anthracycline-induced cardiotoxicity

Meiners, B., Shenoy, C. & Zordoky, B. N., Aug 29 2018, In: Biology of Sex Differences. 9, 1, 38.

Research output: Contribution to journal › Review article › peer-review

Open Access

40 Scopus citations

Clinical Pharmacokinetics of Amikacin in Pediatric Patients: A Comprehensive Review of Population Pharmacokinetic Analyses

Illamola, S. M., Sherwin, C. M. & van Hasselt, J. G. C., Oct 1 2018, In: Clinical Pharmacokinetics. 57, 10, p. 1217-1228 12 p.

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Experimental and Clinical Pharmacology

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