Experimental and Clinical Pharmacology

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2014

A 16-month community-based intervention to increase aspirin use for primary prevention of cardiovascular disease

Oldenburg, N. C., Duval, S., Luepker, R. V., Finnegan, J. R., LaMarre, H., Peterson, K. A., Zantek, N. D., Jacobs, G., Straka, R. J., Miller, K. H. & Hirsch, A. T., May 2014, In : Preventing Chronic Disease. 11, 5, 130378.

Research output: Contribution to journalArticle

8 Scopus citations

A DPYD variant (y186c) specific to individuals of african descent in a patient with life-threatening 5-fu toxic effects: Potential for an individualized medicine approach

Saif, M. W., Lee, A. M., Offer, S. M., McConnell, K., Relias, V. & Diasio, R. B., Jan 2014, In : Mayo Clinic Proceedings. 89, 1, p. 131-136 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Age-related physiologic changes, risk of adverse effects guide your prescribing

Hong, I. S. & Bishop, J. R., Jan 1 2014, In : Current Psychiatry. 13, 10, p. 36-52 17 p.

Research output: Contribution to journalArticle

1 Scopus citations

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation

Zordoky, B. N. M., Nagendran, J., Pulinilkunnil, T., Kienesberger, P. C., Masson, G., Waller, T. J., Kemp, B. E., Steinberg, G. R. & Dyck, J. R. B., Aug 15 2014, In : Circulation research. 115, 5, p. 518-524 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

A pilot study assessing pharmacokinetics and tolerability of oral and intravenous baclofen in healthy adult volunteers

Agarwal, S. K., Kriel, R. L., Cloyd, J. C., Coles, L. D., Scherkenbach, L. A., Tobin, M. H. & Krach, L. E., Jan 1 2014, In : Journal of Child Neurology. 30, 1, p. 37-41 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Are individual differences in appetitive and defensive motivation related? A psychophysiological examination in two samples

Sarapas, C., Katz, A. C., Nelson, B. D., Campbell, M. L., Bishop, J. R., Robison-Andrew, E. J., Altman, S. E., Gorka, S. M. & Shankman, S. A., May 2014, In : Cognition and Emotion. 28, 4, p. 636-655 20 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association of variants in DRD2 and GRM3 with motor and cognitive function in first-episode psychosis

Lencer, R., Bishop, J. R., Harris, M. S. H., Reilly, J. L., Patel, S., Kittles, R., Prasad, K. M., Nimgaonkar, V. L., Keshavan, M. S. & Sweeney, J. A., Jun 2014, In : European Archives of Psychiatry and Clinical Neuroscience. 264, 4, p. 345-355 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Association study of the let-7 miRNA-complementary site variant in the 3′ untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 clinical trial)

Sha, D., Lee, A. M., Shi, Q., Alberts, S. R., Sargent, D. J., Sinicrope, F. A. & Diasio, R. B., Jun 15 2014, In : Clinical Cancer Research. 20, 12, p. 3319-3327 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Bayesian approach to estimate AUC, partition coefficient and drug targeting index for studies with serial sacrifice design

Wang, T., Baron, K., Zhong, W., Brundage, R. & Elmquist, W., Mar 2014, In : Pharmaceutical research. 31, 3, p. 649-659 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cell permeable vanX inhibitors as vancomycin re-sensitizing agents

Muthyala, R., Rastogi, N., Shin, W. S., Peterson, M. L. & Sham, Y. Y., Jun 1 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 11, p. 2535-2538 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
7 Scopus citations

Clinical drug response can be predicted using baseline gene expression levels and in vitro drug sensitivity in cell lines

Geeleher, P., Cox, N. J. & Huang, R. S., Mar 3 2014, In : Genome biology. 15, 3, R47.

Research output: Contribution to journalArticle

111 Scopus citations

Clinically Relevant Variants - Identifying, Collecting, Interpreting, and Disseminating: The 2013 Annual Scientific Meeting of the Human Genome Variation Society

Stanley, C. M., Sunyaev, S. R., Greenblatt, M. S. & Oetting, W. S., Apr 2014, In : Human mutation. 35, 4, p. 505-510 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Comparison of 3-Factor Prothrombin Complex Concentrate and Low-Dose Recombinant Factor VIIa for Warfarin Reversal

Chapman, S. A., Irwin, E. D., Abou-Karam, N. M., Rupnow, N. M., Hutson, K. E., Vespa, J. & Roach, R. M., Apr 15 2014, In : World Journal of Emergency Surgery. 9, 1, 27.

Research output: Contribution to journalArticle

10 Scopus citations

Disease and drug effects on internally-generated and externally-elicited responses in first episode schizophrenia and psychotic bipolar disorder

Keedy, S. K., Bishop, J. R., Weiden, P. J., Sweeney, J. A., Rosen, C., Marvin, R. & Reilly, J. L., Oct 1 2014, In : Schizophrenia Research. 159, 1, p. 101-106 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dopamine transporter genotype and stimulant dose-response in youth with attention-deficit/hyperactivity disorder

Stein, M. A., Waldman, I., Newcorn, J., Bishop, J., Kittles, R. & Cook, E. H., Jun 1 2014, In : Journal of child and adolescent psychopharmacology. 24, 5, p. 238-244 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147)

Lee, A. M., Shi, Q., Pavey, E., Alberts, S. R., Sargent, D. J., Sinicrope, F. A., Berenberg, J. L., Goldberg, R. M. & Diasio, R. B., Dec 1 2014, In : Journal of the National Cancer Institute. 106, 12, dju298.

Research output: Contribution to journalArticle

74 Scopus citations

Educational outcomes necessary to enter pharmacy residency training

Hester, E. K., McBane, S. E., Bottorff, M. B., Carnes, T. A., Dell, K., Gonyeau, M. J., Greco, A. J., McConnell, K. J., Skaar, D. J., Splinter, M. Y. & Trujillo, T. C., Apr 2014, In : Pharmacotherapy. 34, 4, p. e22-e25

Research output: Contribution to journalArticle

6 Scopus citations

Emotional well-being of living kidney donors: Findings from the RELIVE study

Jowsey, S. G., Jacobs, C., Gross, C. R., Hong, B. A., Messersmith, E. E., Gillespie, B. W., Beebe, T. J., Kew, C., Matas, A., Yusen, R. D., Hill-Callahan, M., Odim, J. & Taler, S. J., Nov 1 2014, In : American Journal of Transplantation. 14, 11, p. 2535-2544 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Encapsulation in nanoparticles improves anti-cancer efficacy of carboplatin

Sadhukha, T. & Prabha, S., Aug 2014, In : AAPS PharmSciTech. 15, 4, p. 1029-1038 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Ethnic and genetic factors in methadone pharmacokinetics: A population pharmacokinetic study

Bart, G., Lenz, S., Straka, R. J. & Brundage, R., Dec 1 2014, In : Drug and alcohol dependence. 145, p. 185-193 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention

Nicol, M. R., Fedoriw, Y., Mathews, M., Prince, H. M. A., Patterson, K. B., Geller, E., Mollan, K., Mathews, S., Kroetz, D. L. & Kashuba, A. D. M., May 2014, In : Journal of Clinical Pharmacology. 54, 5, p. 574-583 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Functional Fcgamma Receptor Polymorphisms Are Associated with Human Allergy

Wu, J., Lin, R., Huang, J., Guan, W., Oetting, W. S., Sriramarao, P. & Blumenthal, M. N., Feb 21 2014, In : PloS one. 9, 2, e89196.

Research output: Contribution to journalArticle

13 Scopus citations

Gamma-Aminobutyric Acid System Genes-No Evidence for a Role in Alcohol Use and Abuse in a Community-Based Sample

Irons, D. E., Iacono, W. G., Oetting, W. S., Kirkpatrick, R. M., Vrieze, S. I., Miller, M. B. & Mcgue, M., Apr 2014, In : Alcoholism: Clinical and Experimental Research. 38, 4, p. 938-947 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol

Feitosa, M. F., Wojczynski, M. K., Straka, R., Kammerer, C. M., Lee, J. H., Kraja, A. T., Christensen, K., Newman, A. B., Province, M. A. & Borecki, I. B., Jan 1 2014, In : Frontiers in Genetics. 5, JUN, Article 159.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic predictor of working memory and prefrontal function in women with HIV

Sundermann, E. E., Bishop, J. R., Rubin, L. H., Little, D. M., Meyer, V. J., Martin, E., Weber, K., Cohen, M. & Maki, P. M., Jan 1 2014, In : Journal of neurovirology. 21, 1, p. 81-91 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate

Frazier-Wood, A. C., Wojczynski, M. K., Borecki, I. B., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Straka, R. J., Tsai, M. Y., Tiwari, H. K. & Arnett, D. K., Aug 25 2014, In : Biology. 3, 3, p. 536-550 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response

An, P., Straka, R. J., Pollin, T. I., Feitosa, M. F., Wojczynski, M. K., Daw, E. W., O'Connell, J. R., Gibson, Q., Ryan, K. A., Hopkins, P. N., Tsai, M. Y., Lai, C. Q., Province, M. A., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Jul 2014, In : Human Genetics. 133, 7, p. 919-930 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genome-wide interrogation of longitudinal FEV1in children with asthma

Wu, K., Gamazon, E. R., Im, H. K., Geeleher, P., White, S. R., Solway, J., Clemmer, G. L., Weiss, S. T., Tantisira, K. G., Cox, N. J., Ratain, M. J. & Huang, R. S., Sep 15 2014, In : American journal of respiratory and critical care medicine. 190, 6, p. 619-627 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Healthcare utilization and costs in persons with insomnia in a managed care population

Anderson, L. H., Whitebird, R. R., Schultz, J., McEvoy, C. E., Kreitzer, M. J. & Gross, C. R., May 2014, In : American Journal of Managed Care. 20, 5, p. e157-e165

Research output: Contribution to journalArticle

8 Scopus citations

Hexanoic acid and polyethylene glycol double grafted amphiphilic chitosan for enhanced gene delivery: Influence of hydrophobic and hydrophilic substitution degree

Layek, B., Haldar, M. K., Sharma, G., Lipp, L., Mallik, S. & Singh, J., Mar 3 2014, In : Molecular Pharmaceutics. 11, 3, p. 982-994 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

How mindfulness changed my sleep: Focus groups with chronic insomnia patients

Hubbling, A., Reilly-Spong, M., Kreitzer, M. J. & Gross, C. R., Feb 10 2014, In : BMC Complementary and Alternative Medicine. 14, 50.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Identifying and validating a combined mRNA and MicroRNA signature in response to imatinib treatment in a chronic myeloid leukemia cell line

Bhutra, S., Lenkala, D., LaCroix, B., Ye, M. & Huang, R. S., Dec 15 2014, In : PloS one. 9, 12, e115003.

Research output: Contribution to journalArticle

8 Scopus citations

Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers

Chen, Z., Gulzar, Z. G., St. Hill, C. A., Walcheck, B. & Brooks, J. D., Jul 2014, In : Prostate. 74, 10, p. 1059-1067 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

In search of rare variants: Preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes

Vrieze, S. I., Malone, S. M., Vaidyanathan, U., Kwong, A., Kang, H. M., Zhan, X., Flickinger, M., Irons, D., Jun, G., Locke, A. E., Pistis, G., Porcu, E., Levy, S., Myers, R. M., Oetting, W., Mcgue, M., Abecasis, G. & Iacono, W. G., Dec 1 2014, In : Psychophysiology. 51, 12, p. 1309-1320 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity

LaCroix, B., Gamazon, E. R., Lenkala, D., Im, H. K., Geeleher, P., Ziliak, D., Cox, N. J. & Huang, R. S., Apr 16 2014, In : BMC Genomics. 15, 1, 292.

Research output: Contribution to journalArticle

19 Scopus citations

In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancer

Frik, M., Martínez, A., Elie, B. T., Gonzalo, O., Ramírez De Mingo, D., Sanaú, M., Sánchez-Delgado, R., Sadhukha, T., Prabha, S., Ramos, J. W., Marzo, I. & Contel, M., Dec 11 2014, In : Journal of medicinal chemistry. 57, 23, p. 9995-10012 18 p.

Research output: Contribution to journalArticle

49 Scopus citations

Model-based lamotrigine clearance changes during pregnancy: Clinical implication

Polepally, A. R., Pennell, P. B., Brundage, R. C., Stowe, Z. N., Newport, D. J., Viguera, A. C., Ritchie, J. C. & Birnbaum, A. K., Jan 1 2014, In : Annals of Clinical and Translational Neurology. 1, 2, p. 99-106 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Multifunctional polymersomes for cytosolic delivery of gemcitabine and doxorubicin to cancer cells

Nahire, R., Haldar, M. K., Paul, S., Ambre, A. H., Meghnani, V., Layek, B., Katti, K. S., Gange, K. N., Singh, J., Sarkar, K. & Mallik, S., Aug 2014, In : Biomaterials. 35, 24, p. 6482-6497 16 p.

Research output: Contribution to journalArticle

60 Scopus citations

Next-generation sequencing for lung cancer

Wu, K., Huang, R. S., House, L. & Cho, W. C., 2014, In : Chinese Journal of Lung Cancer. 17, 1, p. C1-C12

Research output: Contribution to journalArticle

Nod2 deficiency protects mice from cholestatic liver disease by increasing renal excretion of bile acids

Wang, L., Hartmann, P., Haimerl, M., Bathena, S. P., Sjöwall, C., Almer, S., Alnouti, Y., Hofmann, A. F. & Schnabl, B., Jun 2014, In : Journal of Hepatology. 60, 6, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
41 Scopus citations

Pharmacokinetics and pharmacodynamics of intravenous baclofen in dogs: A preliminary study

Scherkenbach, L. A., Coles, L. D., Patterson, E. E., Cloyd, J. C., Krach, L. E. & Kriel, R. L., Jul 2014, In : Journal of Pharmacy and Pharmacology. 66, 7, p. 935-942 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pharmacometric characterization of efavirenz developmental pharmacokinetics and pharmacogenetics in HIV-Infected children

Salem, A. H., Fletcher, C. V. & Brundage, R. C., Jan 1 2014, In : Antimicrobial agents and chemotherapy. 58, 1, p. 136-143 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Poly-omic prediction of complex traits: OmicKriging

Wheeler, H. E., Aquino-Michaels, K., Gamazon, E. R., Trubetskoy, V. V., Dolan, M. E., Huang, R. S., Cox, N. J. & Im, H. K., Jul 2014, In : Genetic epidemiology. 38, 5, p. 402-415 14 p.

Research output: Contribution to journalArticle

22 Scopus citations
10 Scopus citations

Quality of life in elderly kidney transplant recipients

Weber, M., Faravardeh, A., Jackson, S., Berglund, D., Spong, R., Matas, A. J., Gross, C. R. & Ibrahim, H. N., Oct 1 2014, In : Journal of the American Geriatrics Society. 62, 10, p. 1877-1882 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reduced levels of vasopressin and reduced behavioral modulation of oxytocin in psychotic disorders

Rubin, L. H., Sue Carter, C., Bishop, J. R., Pournajafi-Nazarloo, H., Drogos, L. L., Kristian Hill, S., Ruocco, A. C., Keedy, S. K., Reilly, J. L., Keshavan, M. S., Pearlson, G. D., Tamminga, C. A., Gershon, E. S. & Sweeney, J. A., Nov 1 2014, In : Schizophrenia bulletin. 40, 6, p. 1374-1384 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Report of the 2013-2014 Academic Affairs Committee

Cain, J., Conway, J. M., DiVall, M. V., Erstad, B. L., Lockman, P. R., Ressler, J. C., Schwartz, A. H., Stolte, S. & Nemire, R. E., Dec 15 2014, In : American Journal of Pharmaceutical Education. 78, 10, p. 1-8 8 p., S23.

Research output: Contribution to journalArticle

16 Scopus citations

Safety of an intravenous formulation of lamotrigine

Conway, J. M., Birnbaum, A. K., Leppik, I. E., Pennell, P. B., White, J. R., Rarick, J. O. & Remmel, R. P., May 2014, In : Seizure. 23, 5, p. 390-392 3 p.

Research output: Contribution to journalArticle

5 Scopus citations