Experimental and Clinical Pharmacology

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2015

Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

Li, Y. R., van Setten, J., Verma, S. S., Lu, Y., Holmes, M. V., Gao, H., Lek, M., Nair, N., Chandrupatla, H., Chang, B., Karczewski, K. J., Wong, C., Mohebnasab, M., Mukhtar, E., Phillips, R., Tragante, V., Hou, C., Steel, L., Lee, T., Garifallou, J. & 46 others, Guettouche, T., Cao, H., Guan, W., Himes, A., van Houten, J., Pasquier, A., Yu, R., Carrigan, E., Miller, M. B., Schladt, D., Akdere, A., Gonzalez, A., Llyod, K. M., McGinn, D., Gangasani, A., Michaud, Z., Colasacco, A., Snyder, J., Thomas, K., Wang, T., Wu, B., Alzahrani, A. J., Al-Ali, A. K., Al-Muhanna, F. A., Al-Rubaish, A. M., Al-Mueilo, S., Monos, D. S., Murphy, B., Olthoff, K. M., Wijmenga, C., Webster, T., Kamoun, M., Balasubramanian, S., Lanktree, M. B., Oetting, W. S., Garcia-Pavia, P., MacArthur, D. G., de Bakker, P. I. W., Hakonarson, H., Birdwell, K. A., Jacobson, P. A., Ritchie, M. D., Asselbergs, F. W., Israni, A. K., Shaked, A. & Keating, B. J., Oct 1 2015, In : Genome medicine. 7, 1, 90.

Research output: Contribution to journalArticle

32 Scopus citations

Design and implementation of the international genetics and translational research in transplantation network

Keating, B. J., Van Setten, J., Jacobson, P. A., Holmes, M. V., Verma, S. S., Chandrupatla, H. R., Nair, N., Gao, H., Li, Y. R., Chang, B. L., Wong, C., Phillips, R., Cole, B. S., Mukhtar, E., Zhang, W., Cao, H., Mohebnasab, M., Hou, C., Lee, T., Steel, L. & 31 others, Shaked, O., Garifallou, J., Miller, M. B., Karczewski, K. J., Akdere, A., Gonzalez, A., Lloyd, K. M., McGinn, D., Michaud, Z., Colasacco, A., Lek, M., Fu, Y., Pawashe, M., Guettouche, T., Himes, A., Perez, L., Guan, W., Wu, B., Schladt, D., Menon, M., Zhang, Z., Tragante, V., De Jonge, N., Otten, H. G., De Weger, R. A., Van De Graaf, E. A., Baan, C. C., Manintveld, O. C., De Vlaminck, I., Oetting, W. S. & The International Genetics & Translational Research in Transplantation Network (iGeneTRAiN), Oct 23 2015, In : Transplantation. 99, 11, p. 2401-2412 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Development of an adverse-event coping scale (AECS) using item response theory

Park, T., Hadsall, R. S., Schommer, J. C., Gross, C. R., Rector, T. S. & Davison, M. L., Sep 1 2015, In : Research in Social and Administrative Pharmacy. 11, 5, p. 651-663 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Development of benzodiazepines for out-of-hospital management of seizure emergencies

Agarwal, S. K. & Cloyd, J. C., Feb 20 2015, In : Neurology: Clinical Practice. 5, 1, p. 80-85 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Differentially expressed gene transcripts using RNA sequencing from the blood of immunosuppressed kidney allograft recipients

Dorr, C., Wu, B., Guan, W., Muthusamy, A., Sanghavi, K., Schladt, D. P., Maltzman, J. S., Scherer, S. E., Brott, M. J., Matas, A. J., Jacobson, P. A., Oetting, W. S. & Israni, A. K., May 6 2015, In : PloS one. 10, 5, e0125045.

Research output: Contribution to journalArticle

17 Scopus citations

Effects of lithium on cortical thickness and hippocampal subfield volumes in psychotic bipolar disorder

Giakoumatos, C. I., Nanda, P., Mathew, I. T., Tandon, N., Shah, J., Bishop, J. R., Clementz, B. A., Pearlson, G. D., Sweeney, J. A., Tamminga, C. A. & Keshavan, M. S., Feb 1 2015, In : Journal of Psychiatric Research. 61, p. 180-187 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Efficacy and safety of perampanel in the subgroup of elderly patients included in the phase III epilepsy clinical trials

Leppik, I. E., Wechsler, R. T., Williams, B., Yang, H., Zhou, S. & Laurenza, A., Feb 1 2015, In : Epilepsy Research. 110, p. 216-220 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Efficacy of skin and nasal povidone-iodine preparation against mupirocin-resistant methicillin-resistant Staphylococcus aureus and S. aureus within the anterior nares

Anderson, M. J., David, M. L., Scholz, M., Bull, S. J., Morse, D., Hulse-Stevens, M. & Peterson, M. L., May 1 2015, In : Antimicrobial agents and chemotherapy. 59, 5, p. 2765-2773 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma

Nath, A., Li, I., Roberts, L. R. & Chan, C., Oct 1 2015, In : Scientific Reports. 5, 14752.

Research output: Contribution to journalArticle

92 Scopus citations

Emotional and financial experiences of kidney donors over the past 50 years: The RELIVE study

Jacobs, C. L., Gross, C. R., Messersmith, E. E., Hong, B. A., Gillespie, B. W., Hill-Callahan, P., Taler, S. J., Jowsey, S. G., Beebe, T. J., Matas, A. J., Odim, J., Ibrahimon, H. N. & RELIVE Study Group, Dec 7 2015, In : Clinical Journal of the American Society of Nephrology. 10, 12, p. 2221-2231 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Escitalopram pharmacogenetics: CYP2C19 relationships with dosing and clinical outcomes in autism spectrum disorder

Bishop, J. R., Najjar, F., Rubin, L. H., Guter, S. J., Owley, T., Mosconi, M. W., Jacob, S. & Cook, E. H., Nov 11 2015, In : Pharmacogenetics and genomics. 25, 11, p. 548-554 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genetic Mechanism of Human Neutrophil Antigen 2 Deficiency and Expression Variations

Li, Y., Mair, D. C., Schuller, R. M., Li, L. & Wu, J., May 1 2015, In : PLoS genetics. 11, 5, e1005255.

Research output: Contribution to journalArticle

19 Scopus citations

Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients

Ziv, E., Dean, E., Hu, D., Martino, A., Serie, D., Curtin, K., Campa, D., Aftab, B., Bracci, P., Buda, G., Zhao, Y., Caswell-Jin, J., Diasio, R., Dumontet, C., Dudziński, M., Fejerman, L., Greenberg, A., Huntsman, S., Jamroziak, K., Jurczyszyn, A. & 18 others, Kumar, S., Atanackovic, D., Glenn, M., Cannon-Albright, L. A., Jones, B., Lee, A., Marques, H., Martin, T., Martinez-Lopez, J., Rajkumar, V., Sainz, J., Vangsted, A. J., Wątek, M., Wolf, J., Slager, S., Camp, N. J., Canzian, F. & Vachon, C., Jul 22 2015, In : Nature communications. 6, 7539.

Research output: Contribution to journalArticle

20 Scopus citations

Glycerol monolaurate microbicide protection against repeat high-dose SIV vaginal challenge

Haase, A. T., Rakasz, E., Schultz-Darken, N., Nephew, K., Weisgrau, K. L., Reilly, C. S., Li, Q., Southern, P. J., Rothenberger, M., Peterson, M. L. & Schlievert, P. M., Jun 9 2015, In : PloS one. 10, 6, e0129465.

Research output: Contribution to journalArticle

11 Scopus citations

Heterometallic titanium-gold complexes inhibit renal cancer cells in vitro and in vivo

Fernández-Gallardo, J., Elie, B. T., Sadhukha, T., Prabha, S., Sanaú, M., Rotenberg, S. A., Ramos, J. W. & Contel, M., Jun 23 2015, In : Chemical Science. 6, 9, p. 5269-5283 15 p.

Research output: Contribution to journalArticle

56 Scopus citations
26 Scopus citations

IL-1β reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E2

Al-Kofahi, M., Becker, F., Gavins, F. N. E., Woolard, M. D., Tsunoda, I., Wang, Y., Ostanin, D., Zawieja, D. C., Muthuchamy, M., Von Der Weid, P. Y. & Alexander, J. S., Aug 1 2015, In : British Journal of Pharmacology. 172, 16, p. 4038-4051 14 p.

Research output: Contribution to journalArticle

16 Scopus citations

Impact of Antipsychotic Treatment on Attention and Motor Learning Systems in First-Episode Schizophrenia

Keedy, S. K., Reilly, J. L., Bishop, J. R., Weiden, P. J. & Sweeney, J. A., Mar 1 2015, In : Schizophrenia bulletin. 41, 2, p. 355-365 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Interrelationships among cortisol, 17-hydroxyprogesterone, and androstenendione exposures in the management of children with congenital adrenal hyperplasia

Sarafoglou, K., Zimmerman, C. L., Gonzalez-Bolanos, M. T., Willis, B. A. & Brundage, R., Jan 2015, In : Journal of Investigative Medicine. 63, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
19 Scopus citations

Intravenous carbamazepine as short-term replacement therapy for oral carbamazepine in adults with epilepsy: Pooled tolerability results from two open-label trials

Lee, D., Kalu, U., Halford, J. J., Biton, V., Cloyd, J., Klein, P., Bekersky, I., Peng, G., Dheerendra, S. & Tolbert, D., Jun 1 2015, In : Epilepsia. 56, 6, p. 906-914 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Lactobacillus crispatus inhibits growth of Gardnerella vaginalis and Neisseria gonorrhoeae on a porcine vaginal mucosa model

Breshears, L. M., Edwards, V. L., Ravel, J. & Peterson, M. L., Dec 9 2015, In : BMC microbiology. 15, 1, 276.

Research output: Contribution to journalArticle

36 Scopus citations

Mechanisms of Antioxidant Induction with High-Dose N-Acetylcysteine in Childhood Cerebral Adrenoleukodystrophy

Kartha, R. V., Zhou, J., Basso, L., Schröder, H., Orchard, P. J. & Cloyd, J., Dec 1 2015, In : CNS Drugs. 29, 12, p. 1041-1047 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Metabolomic fingerprint of heart failure with preserved ejection fraction

Zordoky, B. N., Sung, M. M., Ezekowitz, J., Mandal, R., Han, B., Bjorndahl, T. C., Bouatra, S., Anderson, T., Oudit, G. Y., Wishart, D. S. & Dyck, J. R. B., May 1 2015, In : PloS one. 10, 5, e0124844.

Research output: Contribution to journalArticle

59 Scopus citations

Microbiological assessment of polymyxin B components tested alone and in combination

Kassamali, Z., Prince, R. A., Danziger, L. H., Rotschafer, J. C., Rhomberg, P. R. & Jones, R. N., Dec 1 2015, In : Antimicrobial agents and chemotherapy. 59, 12, p. 7823-7825 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Models for predicting effective HIV chemoprevention in women

Nicol, M. R., Emerson, C. W., Prince, H. M. A., Nelson, J. A. E., Fedoriw, Y., Sykes, C., Geller, E. J., Patterson, K. B., Cohen, M. S. & Kashuba, A. D. M., Apr 1 2015, In : Journal of Acquired Immune Deficiency Syndromes. 68, 4, p. 369-376 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Multigene predictors of tacrolimus exposure in kidney transplant recipients

Pulk, R. A., Schladt, D. S., Oetting, W. S., Guan, W., Israni, A. K., Matas, A. J., Remmel, R. P. & Jacobson, P. A., Jul 1 2015, In : Pharmacogenomics. 16, 8, p. 841-854 14 p.

Research output: Contribution to journalArticle

24 Scopus citations

Outcomes and risk factors for mortality among patients treated with carbapenems for klebsiella spp. bacteremia

Biehle, L. R., Cottreau, J. M., Thompson, D. J., Filipek, R. L., O'Donnell, J. N., Lasco, T. M., Mahoney, M. V. & Hirsch, E. B., Nov 1 2015, In : PloS one. 10, 11, e0143845.

Research output: Contribution to journalArticle

11 Scopus citations

Peripheral blood IRF1 expression as a marker for glucocorticoid sensitivity

Chapin, W. J., Lenkala, D., Mai, Y., Mao, Y., White, S. R. & Huang, R. S., Mar 13 2015, In : Pharmacogenetics and genomics. 25, 3, p. 126-133 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IV administration

Wakaskar, R. R., Bathena, S. P. R., Tallapaka, S. B., Ambardekar, V. V., Gautam, N., Thakare, R., Simet, S. M., Curran, S. M., Singh, R. K., Dong, Y. & Vetro, J. A., Mar 2015, In : Pharmaceutical research. 32, 3, p. 1028-1044 17 p.

Research output: Contribution to journalArticle

13 Scopus citations

Pharmacogenetic associations of the type-3 metabotropic glutamate receptor (GRM3) gene with working memory and clinical symptom response to antipsychotics in first-episode schizophrenia

Bishop, J. R., Reilly, J. L., Harris, M. S. H., Patel, S. R., Kittles, R., Badner, J. A., Prasad, K. M., Nimgaonkar, V. L., Keshavan, M. S. & Sweeney, J. A., Jan 2015, In : Psychopharmacology. 232, 1, p. 145-154 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Pharmacogenetic study of serotonin transporter and 5HT2A genotypes in autism

Najjar, F., Owley, T., Mosconi, M. W., Jacob, S., Hur, K., Guter, S. J., Sweeney, J. A., Gibbons, R. D., Cook, E. H. & Bishop, J. R., Aug 1 2015, In : Journal of child and adolescent psychopharmacology. 25, 6, p. 467-474 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
6 Scopus citations

Plasma genetic and genomic abnormalities predict treatment response and clinical outcome in advanced prostate cancer

Xia, S., Kohli, M., Du, M., Dittmar, R. L., Lee, A., Nandy, D., Yuan, T., Guo, Y., Wang, Y., Tschannen, M. R., Worthey, E., Jacob, H., See, W., Kilari, D., Wang, X., Hovey, R. L., Huang, C. C. & Wang, L., Jan 1 2015, In : Oncotarget. 6, 18, p. 16411-16421 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Predicting response to histone deacetylase inhibitors using high-throughput genomics

Geeleher, P., Loboda, A., Lenkala, D., Wang, F., LaCroix, B., Karovic, S., Wang, J., Nebozhyn, M., Chisamore, M., Hardwick, J., Maitland, M. L. & Huang, R. S., Jan 1 2015, In : Journal of the National Cancer Institute. 107, 11, djv247.

Research output: Contribution to journalArticle

9 Scopus citations

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration

Liu, P., Reed, M. N., Kotilinek, L. A., Grant, M. K. O., Forster, C. L., Qiang, W., Shapiro, S. L., Reichl, J. H., Chiang, A. C. A., Jankowsky, J. L., Wilmot, C. M., Cleary, J. P., Zahs, K. R. & Ashe, K. H., Jun 23 2015, In : Cell reports. 11, 11, p. 1760-1771 12 p.

Research output: Contribution to journalArticle

77 Scopus citations

Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing

Kowalsky, C. A., Faber, M. S., Nath, A., Dann, H. E., Kelly, V. W., Liu, L., Shanker, P., Wagner, E. K., Maynard, J. A., Chan, C. & Whitehead, T. A., Oct 30 2015, In : Journal of Biological Chemistry. 290, 44, p. 26457-26470 14 p.

Research output: Contribution to journalArticle

33 Scopus citations

Referential processing in the human brain: An Event-Related Potential (ERP) study

Barkley, C. M., Kluender, R. & Kutas, M., Dec 10 2015, In : Brain Research. 1629, p. 143-159 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Regressing to Prior Response Preference after Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings from the B-SNIP Study

Hill, S. K., Reilly, J. L., Ragozzino, M. E., Rubin, L. H., Bishop, J. R., Gur, R. C., Gershon, E. S., Tamminga, C. A., Pearlson, G. D., Keshavan, M. S., Keefe, R. S. E. & Sweeney, J. A., Jul 1 2015, In : Schizophrenia bulletin. 41, 4, p. 940-950 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

SNP genotyping using TaqMan® technology: The CYP2D6∗17 assay conundrum

Gaedigk, A., Freeman, N., Hartshorne, T., Riffel, A. K., Irwin, D., Bishop, J. R., Stein, M. A., Newcorn, J. H., Jaime, L. K. M., Cherner, M. & Leeder, J. S., Mar 19 2015, In : Scientific reports. 5, 9257.

Research output: Contribution to journalArticle

16 Scopus citations
7 Scopus citations

Surface Density-Induced Pleating of a Lipid Monolayer Drives Nascent High-Density Lipoprotein Assembly

Segrest, J. P., Jones, M. K., Catte, A., Manchekar, M., Datta, G., Zhang, L., Zhang, R., Li, L., Patterson, J. C., Palgunachari, M. N., Oram, J. F. & Ren, G., Jul 9 2015, In : Structure. 23, 7, p. 1214-1226 13 p., 3193.

Research output: Contribution to journalArticle

23 Scopus citations

Telephone-adapted mindfulness-based stress reduction (tMBSR) for patients awaiting kidney transplantation: Trial design, rationale and feasibility

Reilly-Spong, M., Reibel, D., Pearson, T., Koppa, P. & Gross, C. R., May 1 2015, In : Contemporary Clinical Trials. 42, p. 169-184 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

The mediating effect of prefrontal asymmetry on the relationship between the COMT Val158Met SNP and trait consummatory positive affect

Katz, A. C., Sarapas, C., Bishop, J. R., Patel, S. R. & Shankman, S. A., Jul 4 2015, In : Cognition and Emotion. 29, 5, p. 867-881 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia

Abner, E. L., Schmitt, F. A., Nelson, P. T., Lou, W., Wan, L., Gauriglia, R., Dodge, H. H., Woltjer, R. L., Yu, L., Bennett, D. A., Schneider, J. A., Chen, R., Masaki, K., Katz, M. J., Lipton, R. B., Dickson, D. W., Lim, K. O., Hemmy, L. S., Cairns, N. J., Grant, E. & 4 others, Tyas, S. L., Xiong, C., Fardo, D. W. & Kryscio, R. J., Mar 2015, In : Design Studies. 1, 2015, p. 56-73 18 p.

Research output: Contribution to journalArticle

Urinary bile acids as biomarkers for liver diseases I. stability of the baseline profile in healthy subjects

Bathena, S. P. R., Thakare, R., Gautam, N., Mukherjee, S., Olivera, M., Meza, J. & Alnouti, Y., Feb 1 2015, In : Toxicological Sciences. 143, 2, p. 296-307 12 p., kfu227.

Research output: Contribution to journalArticle

25 Scopus citations

Urinary bile acids as biomarkers for liver diseases II. signature profiles in patients

Bathena, S. P. R., Thakare, R., Gautam, N., Mukherjee, S., Olivera, M., Meza, J. & Alnouti, Y., Feb 1 2015, In : Toxicological Sciences. 143, 2, p. 308-318 11 p., kfu228.

Research output: Contribution to journalArticle

19 Scopus citations
3 Scopus citations

Using automatic speech recognition to assess spoken responses to cognitive tests of semantic verbal fluency

Pakhomov, S. V. S., Marino, S. E., Banks, S. & Bernick, C., Dec 1 2015, In : Speech Communication. 75, p. 14-26 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies

Siegel, R. A., Kapoor, M., Cheryala, N., Georg, G. I. & Cloyd, J. C., Aug 1 2015, In : Epilepsy and Behavior. 49, p. 347-350 4 p.

Research output: Contribution to journalArticle

8 Scopus citations