Experimental and Clinical Pharmacology

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2017

Engaging Hmong adults in genomic and pharmacogenomic research: Toward reducing health disparities in genomic knowledge using a community-based participatory research approach

Culhane-Pera, K. A., Straka, R. J., Moua, M. K., Roman, Y., Vue, P., Xiaaj, K., Lo, M. X. & Lor, M., Apr 1 2017, In : Journal of Community Genetics. 8, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Epidermal growth factor receptor signaling enhances the proinflammatory effects of staphylococcus aureus gamma-toxin on the mucosa

Gillman, A. N., Breshears, L. M., Kistler, C. K., Finnegan, P. M., Torres, V. J., Schlievert, P. M. & Peterson, M. L., Jul 1 2017, In : Toxins. 9, 7, 202.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Exploring the link between the germline and somatic genome in cancer

Geeleher, P. & Huang, R. S., Apr 2017, In : Cancer discovery. 7, 4, p. 354-355 2 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Factors in Variability of Serial Gabapentin Concentrations in Elderly Patients with Epilepsy

Conway, J. M., Eberly, L. E., Collins, J. F., Macias, F. M., Ramsay, R. E., Leppik, I. E. & Birnbaum, A. K., Oct 2017, In : Pharmacotherapy. 37, 10, p. 1197-1203 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study

Lencer, R., Mills, L. J., Alliey-Rodriguez, N., Shafee, R., Lee, A. M., Reilly, J. L., Sprenger, A., McDowell, J. E., McCarroll, S. A., Keshavan, M. S., Pearlson, G. D., Tamminga, C. A., Clementz, B. A., Gershon, E. S., Sweeney, J. A. & Bishop, J. R., Oct 24 2017, In : Translational psychiatry. 7, 10, p. e1249

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Genotype-guided tacrolimus dosing in African-American kidney transplant recipients

Sanghavi, K., Brundage, R. C., Miller, M. B., Schladt, D. P., Israni, A. K., Guan, W., Oetting, W. S., Mannon, R. B., Remmel, R. P., Matas, A. J. & Jacobson, P. A., Jan 1 2017, In : Pharmacogenomics Journal. 17, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice

Cheng, S., Wani, W. Y., Hottman, D. A., Jeong, A., Cao, D., LeBlanc, K. J., Saftig, P., Zhang, J. & Li, L., Jul 1 2017, In : Journal of Neurochemistry. 142, 2, p. 297-304 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Implementing pharmacogenomics in modern health care: The 2017 scientific meeting of the Human Genome Variation Society

Lanting, P. & Oetting, W. S., Nov 2017, In : Human mutation. 38, 11, p. 1606-1610 5 p.

Research output: Contribution to journalArticle

Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage

Yanik, M. V., Irvin, M. R., Beasley, T. M., Jacobson, P. A., Julian, B. A. & Limdi, N. A., Nov 2017, In : Pharmacotherapy. 37, 11, p. 1366-1373 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Institutional Profile: Pharmacogenomic research in R Stephanie Huang Laboratory

Geeleher, P., Nath, A. & Huang, R. S., Apr 2017, In : Pharmacogenomics. 18, 6, p. 519-522 4 p.

Research output: Contribution to journalArticle

Integrated microfluidic platform for rapid antimicrobial susceptibility testing and bacterial growth analysis using bead-based biosensor via fluorescence imaging

Sabhachandani, P., Sarkar, S., Zucchi, P. C., Whitfield, B. A., Kirby, J. E., Hirsch, E. B. & Konry, T., Dec 1 2017, In : Microchimica Acta. 184, 12, p. 4619-4628 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Leaves imitate trees: Minnesota Hmong concepts of heredity and applications to genomics research

Culhane-Pera, K. A., Moua, M. K., Vue, P., Xiaaj, K., Lo, M. X. & Straka, R. J., Jan 1 2017, In : Journal of Community Genetics. 8, 1, p. 23-34 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Non-Coding Variation: The 2016 Annual Scientific Meeting of the Human Genome Variation Society

Oetting, W. S., Béroud, C., Brenner, S. E., Greenblatt, M., Karchin, R., Mooney, S. D. & Sunyaev, S., Apr 1 2017, In : Human mutation. 38, 4, p. 460-463 4 p.

Research output: Contribution to journalArticle

Open Access

Perceived motivating factors and barriers for the completion of postgraduate training among American pharmacy students prior to beginning advanced pharmacy practice experiences

Hammond, D. A., Oyler, D. R., Devlin, J. W., Painter, J. T., Bolesta, S., Swanson, J. M., Bailey, B. J., Branan, T., Barletta, J. F., Dunn, B., Haney, J. S., Juang, P., Kane-Gill, S. L., Kiser, T., Shafeeq, H., Skaar, D., Smithburger, P. & Taylor, J., Jan 1 2017, In : American journal of pharmaceutical education. 81, 5, 90.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
Open Access
3 Scopus citations

Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients

Ahmed, G. F., Bathena, S. P. R., Brundage, R. C., Leppik, I. E., Conway, J. M., Schwartz, J. B. & Birnbaum, A. K., Mar 1 2017, In : AAPS Journal. 19, 2, p. 551-556 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phxnlme: An R package that facilitates pharmacometric workflow of Phoenix NLME analyses

Lim, C. N., Liang, S., Feng, K., Chittenden, J., Henry, A., Mouksassi, S. & Birnbaum, A. K., Mar 1 2017, In : Computer Methods and Programs in Biomedicine. 140, p. 121-129 9 p.

Research output: Contribution to journalArticle

Population pharmacokinetic modeling of tenofovir in the genital tract of male HIV-infected patients

Evarist-ANRS EP 49 Study Group, Mar 2017, In : Antimicrobial agents and chemotherapy. 61, 3, e02062-16.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Potential clinical and economic impact of switching branded medications to generics

Straka, R. J., Keohane, D. J. & Liu, L. Z., May 1 2017, In : American journal of therapeutics. 24, 3, p. e278-e289

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Potentially inappropriate medication prescribing in U.S. Older adults with selected chronic conditions

Swanoski, M. T., Little, M., Hill, C. A. S., Ware, K. B., Chapman, S. A. & Lutfiyya, M. N., Sep 2017, In : Consultant Pharmacist. 32, 9, p. 525-534 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prevalence of epilepsy/seizures as a comorbidity of neurologic disorders in nursing homes

Birnbaum, A. K., Leppik, I. E., Svensden, K. & Eberly, L. E., Feb 21 2017, In : Neurology. 88, 8, p. 750-757 8 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Quantitative Contribution of rs75017182 to Dihydropyrimidine Dehydrogenase mRNA Splicing and Enzyme Activity

Nie, Q., Shrestha, S., Tapper, E. E., Trogstad-Isaacson, C. S., Bouchonville, K. J., Lee, A. M., Wu, R., Jerde, C. R., Wang, Z., Kubica, P. A., Offer, S. M. & Diasio, R. B., Oct 2017, In : Clinical Pharmacology and Therapeutics. 102, 4, p. 662-670 9 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Randomized Comparison of 3 High-Level Disinfection and Sterilization Procedures for Duodenoscopes

Snyder, G. M., Wright, S. B., Smithey, A., Mizrahi, M., Sheppard, M., Hirsch, E. B., Chuttani, R., Heroux, R., Yassa, D. S., Olafsdottir, L. B., Davis, R. B., Anastasiou, J., Bapat, V., Bidari, K., Pleskow, D. K., Leffler, D., Lane, B., Chen, A., Gold, H. S., Bartley, A. & 2 others, King, A. D. & Sawhney, M. S., Oct 2017, In : Gastroenterology. 153, 4, p. 1018-1025 8 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Rifampin-sirolimus-voriconazole interaction in a hematopoietic cell transplant recipient

Wasko, J. A., Westholder, J. S. & Jacobson, P. A., Jan 1 2017, In : Journal of Oncology Pharmacy Practice. 23, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Safety and acceptability of patient-administered sedatives during mechanical ventilation

Chlan, L. L., Skaar, D. J., Tracy, M. F., Hayes, S. M., Hetland, B. D., Savik, K. & Weinert, C. R., Jul 1 2017, In : American Journal of Critical Care. 26, 4, p. 288-296 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Serum clomipramine and desmethylclomipramine levels in a CYP2C19 and CYP2D6 intermediate metabolizer

Brown, J. T., Schneiderhan, M., Eum, S. & Bishop, J. R., May 2017, In : Pharmacogenomics. 18, 7, p. 601-605 5 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Sex differences in associations of arginine vasopressin and oxytocin with resting-state functional brain connectivity

Rubin, L. H., Yao, L., Keedy, S. K., Reilly, J. L., Bishop, J. R., Carter, C. S., Pournajafi-Nazarloo, H., Drogos, L. L., Tamminga, C. A., Pearlson, G. D., Keshavan, M. S., Clementz, B. A., Hill, S. K., Liao, W., Ji, G. J., Lui, S. & Sweeney, J. A., Jan 1 2017, In : Journal of Neuroscience Research. 95, 1-2, p. 576-586 11 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes

Klingel, S. L., Roke, K., Hidalgo, B., Aslibekyan, S., Straka, R. J., An, P., Province, M. A., Hopkins, P. N., Arnett, D. K., Ordovas, J. M., Lai, C. Q. & Mutch, D. M., Dec 1 2017, In : Lipids. 52, 12, p. 969-980 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
6 Scopus citations

Telephone-adapted Mindfulness-based Stress Reduction (tMBSR) for patients awaiting kidney transplantation

Gross, C. R., Reilly-Spong, M., Park, T., Zhao, R., Gurvich, O. V. & Ibrahim, H. N., Jun 1 2017, In : Contemporary Clinical Trials. 57, p. 37-43 7 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Timing of nicotine lozenge administration to minimize trigger induced craving and withdrawal symptoms

Kotlyar, M., Lindgren, B. R., Vuchetich, J. P., Le, C., Mills, A. M., Amiot, E. & Hatsukami, D. K., Aug 1 2017, In : Addictive Behaviors. 71, p. 18-24 7 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Volatile metabolic diversity of Klebsiella pneumoniae in nutrient-replete conditions

Rees, C. A., Nordick, K. V., Franchina, F. A., Lewis, A. E., Hirsch, E. B. & Hill, J. E., Feb 1 2017, In : Metabolomics. 13, 2, 18.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2016
Open Access
4 Scopus citations

A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies

Irvin, M. R., Rotroff, D. M., Aslibekyan, S., Zhi, D., Hidalgo, B., Motsinger-Reif, A., Marvel, S., Srinivasasainagendra, V., Claas, S. A., Buse, J. B., Straka, R. J., Ordovas, J. M., Borecki, I. B., Guo, X., Chen, I. Y. D., Rotter, J. I., Wagner, M. J. & Arnett, D. K., Jan 1 2016, In : Pharmacogenetics and genomics. 26, 7, p. 324-333 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
5 Scopus citations

A model-based approach to assess the exposure-response relationship of Lorenzo's oil in adrenoleukodystrophy

Ahmed, M. A., Kartha, R. V., Brundage, R. C., Cloyd, J., Basu, C., Carlin, B. P., Jones, R. O., Moser, A. B., Fatemi, A. & Raymond, G. V., Jun 1 2016, In : British Journal of Clinical Pharmacology. 81, 6, p. 1058-1066 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Antipsychotic pharmacogenomics in first episode psychosis: A role for glutamate genes

Stevenson, J. M., Reilly, J. L., Harris, M. S. H., Patel, S. R., Weiden, P. J., Prasad, K. M., Badner, J. A., Nimgaonkar, V. L., Keshavan, M. S., Sweeney, J. A. & Bishop, J. R., Jan 1 2016, In : Translational psychiatry. 6, 2, e739.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Assessment of genetic polymorphisms associated with hyperuricemia or gout in the Hmong

Roman, Y. M., Culhane-Pera, K. A., Menk, J. S. & Straka, R. J., Sep 2016, In : Personalized Medicine. 13, 5, p. 429-440 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients

Perez-Martinez, P., Alcala-Diaz, J. F., Kabagambe, E. K., Garcia-Rios, A., Tsai, M. Y., Delgado-Lista, J., Kolovou, G., Straka, R. J., Gomez-Delgado, F., Hopkins, P. N., Marin, C., Borecki, I., Yubero-Serrano, E. M., Hixson, J. E., Camargo, A., Province, M. A., Lopez-Moreno, J., Rodriguez-Cantalejo, F., Tinahones, F. J., Mikhailidis, D. P. & 4 others, Perez-Jimenez, F., Arnett, D. K., Ordovas, J. M. & Lopez-Miranda, J., Sep 1 2016, In : Journal of Clinical Lipidology. 10, 5, p. 1163-1171 9 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Association between DPYD c.1129-5923 C>G/hapB3 and severe toxicity to 5-fluorouracil-based chemotherapy in stage III colon cancer patients: NCCTG N0147 (Alliance)

Lee, A. M., Shi, Q., Alberts, S. R., Sargent, D. J., Sinicrope, F. A., Berenberg, E. L., Grothey, A., Polite, B., Chan, E., Gill, S., Kahlenberg, M. S., Nair, S. G., Shields, A. F., Goldberg, R. M. & Diasio, R. B., Jan 1 2016, In : Pharmacogenetics and genomics. 26, 3, p. 133-137 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cancer biomarker discovery is improved by accounting for variability in general levels of drug sensitivity in pre-clinical models

Geeleher, P., Cox, N. J. & Huang, R. S., Sep 21 2016, In : Genome biology. 17, 1, 190.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Catechol-O-methyltransferase Val158Met polymorphism and clinical response to antipsychotic treatment in schizophrenia and schizo-affective disorder patients: A meta-analysis

Huang, E., Zai, C. C., Lisoway, A., Maciukiewicz, M., Felsky, D., Tiwari, A. K., Bishop, J. R., Ikeda, M., Molero, P., Ortuno, F., Porcelli, S., Samochowiec, J., Mierzejewski, P., Gao, S., Crespo-Facorro, B., Pelayo-Terán, J. M., Kaur, H., Kukreti, R., Meltzer, H. Y., Lieberman, J. A. & 3 others, Potkin, S. G., Müller, D. J. & Kennedy, J. L., 2016, In : International Journal of Neuropsychopharmacology. 19, 5, 132.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Characterization of transcription factor response kinetics in parallel

Bilgin, B., Nath, A., Chan, C. & Walton, S. P., 2016, In : BMC Biotechnology. 16, 1, 62.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
5 Scopus citations

Clinical Interpretation of Variants from Next-Generation Sequencing: The 2016 Scientific Meeting of the Human Genome Variation Society

Oetting, W. S., Brookes, A. J., Béroud, C. & Taschner, P. E., Oct 1 2016, In : Human mutation. 37, 10, p. 1110-1113 4 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance

Walsh, C. C., Landersdorfer, C. B., McIntosh, M. P., Peleg, A. Y., Hirsch, E. B., Kirkpatrick, C. M. & Bergen, P. J., Aug 1 2016, In : Journal of Antimicrobial Chemotherapy. 71, 8, p. 2218-2229 12 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
Open Access
8 Scopus citations

Common genetic variation in CYP17A1 and response to abiraterone acetate in patients with metastatic castration-resistant prostate cancer

Binder, M., Zhang, B. Y., Hillman, D. W., Kohli, R., Kohli, T., Lee, A. & Kohli, M., Jul 2016, In : International journal of molecular sciences. 17, 7, 1097.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Deconstructing tolerance with clobazam

Gidal, B. E., Wechsler, R. T., Sankar, R., Montouris, G. D., White, H. S., Cloyd, J. C., Kane, M. C., Peng, G., Tworek, D. M., Shen, V. & Isojarvi, J., Oct 25 2016, In : Neurology. 87, 17, p. 1806-1812 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations