Experimental and Clinical Pharmacology

Research Output

Filter
Article

A genome-wide integrative study of microRNAs in human liver

Gamazon, E. R., Innocenti, F., Wei, R., Wang, L., Zhang, M., Mirkov, S., Ramírez, J., Huang, R. S., Cox, N. J., Ratain, M. J. & Liu, W., Jun 13 2013, In : BMC Genomics. 14, 1, 395.

Research output: Contribution to journalArticle

25 Scopus citations

A genome-wide search for allergic response (atopy) genes in three ethnic groups collaborative study of the genetics of asthma

Blumenthal, M. N., Langefeld, C. D., Beaty, T. H., Bleecker, E. R., Ober, C., Lester, L., Lange, E., Barnes, K. C., Wolf, R., King, R. A., Solway, J., Oetting, W., Meyers, D. A. & Rich, S. S., Jan 1 2004, In : Human Genetics. 114, 2, p. 157-164 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

Marsh, D. G., Maestri, N. E., Freidhoff, L. R., Barnes, K. C., Togias, A., Ehrlich, E., Beaty, T., Duffy, D., Rosenthal, R., Imani, F., Dunston, G., Furbert-Harris, P., Malveaux, F., Ober, C., Cox, N. J., Lester, L. A., Peterson, R., Gidley, H., Pluzhnikov, A., Anderson, J. & 31 others, Solway, J., Leff, A., Wolf, R., Wylam, M., Kurtz, B., Richardson, A., Parry, R., Blumenthal, M. N., King, R. A., Oetting, W. S., Drury, D., Rosenberg, A., Daniels, L., McEvoy, C., Lou, J., Hamra, M., Brott, M., Rich, S. S., Spray, B. J., Weber, J. L., Yuan, B., Wang, Z., Bleecker, E. R., Amelung, P., Rechstiner, B., Meyers, D. A., Samet, J., Wiesch, D., Xu, J., Murphy, S. & Banks-Schlegel, S., Apr 1 1997, In : Nature Genetics. 15, 4, p. 389-392 4 p.

Research output: Contribution to journalArticle

640 Scopus citations

A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studies

Irvin, M. R., Rotroff, D. M., Aslibekyan, S., Zhi, D., Hidalgo, B., Motsinger-Reif, A., Marvel, S., Srinivasasainagendra, V., Claas, S. A., Buse, J. B., Straka, R. J., Ordovas, J. M., Borecki, I. B., Guo, X., Chen, I. Y. D., Rotter, J. I., Wagner, M. J. & Arnett, D. K., Jan 1 2016, In : Pharmacogenetics and genomics. 26, 7, p. 324-333 10 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Age-related physiologic changes, risk of adverse effects guide your prescribing

Hong, I. S. & Bishop, J. R., Jan 1 2014, In : Current Psychiatry. 13, 10, p. 36-52 17 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
5 Scopus citations

A Holistic Clustering Methodology for Liver Transplantation Survival

Pruinelli, L., Simon, G. J., Monsen, K. A., Pruett, T. L., Gross, C. R., Radosevich, D. M. & Westra, B. L., Jul 1 2018, In : Nursing research. 67, 4, p. 331-340 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Albinism

Oetting, W. S., Dec 4 1999, In : Current Opinion in Pediatrics. 11, 6, p. 565-571 7 p.

Research output: Contribution to journalArticle

30 Scopus citations
23 Scopus citations

ALK the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)

Morris, S. W., Naeve, C., Mathew, P., James, P. L., Kirstein, M. N., Cui, X. & Witte, D. P., Jan 1 1997, In : Oncogene. 14, 18, p. 2175-2188 14 p.

Research output: Contribution to journalArticle

369 Scopus citations

Allosteric interaction of dynorphin and myelin basic protein with muscarinic receptors

Hu, J. & El-Fakahany, E. E., Jan 1 1993, In : Pharmacology. 47, 6, p. 351-359 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
35 Scopus citations

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

Antoniou, A. C., Wang, X., Fredericksen, Z. S., McGuffog, L., Tarrell, R., Sinilnikova, O. M., Healey, S., Morrison, J., Kartsonaki, C., Lesnick, T., Ghoussaini, M., Barrowdale, D., Peock, S., Cook, M., Oliver, C., Frost, D., Eccles, D., Evans, D. G., Eeles, R., Izatt, L. & 158 others, Chu, C., Douglas, F., Paterson, J., Stoppa-Lyonnet, D., Houdayer, C., Mazoyer, S., Giraud, S., Lasset, C., Remenieras, A., Caron, O., Hardouin, A., Berthet, P., Hogervorst, F. B. L., Rookus, M. A., Jager, A., Van Den Ouweland, A., Hoogerbrugge, N., Van Der Luijt, R. B., Meijers-Heijboer, H., G'mez García, E. B., Devilee, P., Vreeswijk, M. P. G., Lubinski, J., Jakubowska, A., Gronwald, J., Huzarski, T., Byrski, T., G'rski, B., Cybulski, C., Spurdle, A. B., Holland, H., Goldgar, D. E., John, E. M., Hopper, J. L., Southey, M., Buys, S. S., Daly, M. B., Terry, M. B., Schmutzler, R. K., Wappenschmidt, B., Engel, C., Meindl, A., Preisler-Adams, S., Arnold, N., Niederacher, D., Sutter, C., Domchek, S. M., Nathanson, K. L., Rebbeck, T., Blum, J. L., Piedmonte, M., Rodriguez, G. C., Wakeley, K., Boggess, J. F., Basil, J., Blank, S. V., Friedman, E., Kaufman, B., Laitman, Y., Milgrom, R., Andrulis, I. L., Glendon, G., Ozcelik, H., Kirchhoff, T., Vijai, J., Gaudet, M. M., Altshuler, D., Guiducci, C., Loman, N., Harbst, K., Rantala, J., Ehrencrona, H., Gerdes, A. M., Thomassen, M., Sunde, L., Peterlongo, P., Manoukian, S., Bonanni, B., Viel, A., Radice, P., Caldes, T., De La Hoya, M., Singer, C. F., Fink-Retter, A., Greene, M. H., Mai, P. L., Loud, J. T., Guidugli, L., Lindor, N. M., Hansen, T. V. O., Nielsen, F. C., Blanco, I., Lazaro, C., Garber, J., Ramus, S. J., Gayther, S. A., Phelan, C., Narod, S., Szabo, C. I., Benitez, J., Osorio, A., Nevanlinna, H., Heikkinen, T., Caligo, M. A., Beattie, M. S., Hamann, U., Godwin, A. K., Montagna, M., Casella, C., Neuhausen, S. L., Karlan, B. Y., Tung, N., Toland, A. E., Weitzel, J., Olopade, O., Simard, J., Soucy, P., Rubinstein, W. S., Arason, A., Rennert, G., Martin, N. G., Montgomery, G. W., Chang-Claude, J., Flesch-Janys, D., Brauch, H., Severi, G., Baglietto, L., Cox, A., Cross, S. S., Miron, P., Gerty, S. M., Tapper, W., Yannoukakos, D., Fountzilas, G., Fasching, P. A., Beckmann, M. W., Dos Santos Silva, I., Peto, J., Lambrechts, D., Paridaens, R., Rüdiger, T., Försti, A., Winqvist, R., Pylkäs, K., Diasio, R. B., Lee, A. M., Eckel-Passow, J., Vachon, C., Blows, F., Driver, K., Dunning, A., Pharoah, P. P. D., Offit, K., Pankratz, V. S., Hakonarson, H., Chenevix-Trench, G., Easton, D. F. & Couch, F. J., Oct 2010, In : Nature Genetics. 42, 10, p. 885-892 8 p.

Research output: Contribution to journalArticle

242 Scopus citations

Alpha-toxin contributes to biofilm formation among Staphylococcus aureus wound isolates

Anderson, M. J., Schaaf, E., Breshears, L. M., Wallis, H. W., Johnson, J. R., Tkaczyk, C., Sellman, B. R., Sun, J. & Peterson, M. L., Apr 2018, In : Toxins. 10, 4, 157.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Alpha-toxin promotes Staphylococcus aureus mucosal biofilm formation.

Anderson, M. J., Lin, Y. C., Gillman, A. N., Parks, P. J., Schlievert, P. M. & Peterson, M. L., 2012, In : Frontiers in Cellular and Infection Microbiology. 2, 1 p.

Research output: Contribution to journalArticle

45 Scopus citations

Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation

Anwar-mohamed, A., Zordoky, B. N. M., Aboutabl, M. E. & El-Kadi, A. O. S., May 1 2010, In : Pharmacological Research. 61, 5, p. 410-418 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Altered phenytoin clearance during febrile illnesses

Leppik, I. A., Fisher, J., Kriel, R. & Sawchuck, R., Jan 1 1981, In : Neurology. 31, 4 II, 1 p.

Research output: Contribution to journalArticle

Altered phenytoin clearance with febrile illness

Leppik, I. E., Fisher, J., Kriel, R. & Sawchuk, R. J., Oct 1986, In : Neurology. 36, 10, p. 1367-1370 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Alternative splicing of the tyrosinase gene transcript in normal human melanocytes and lymphocytes

Fryer, J. P., Oetting, W. S., Brott, M. J. & King, R. A., Jan 1 2001, In : Journal of Investigative Dermatology. 117, 5, p. 1261-1265 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

A major human oral lysophosphatidic acid species, LPA 18:1, regulates novel genes in human gingival fibroblasts

Cerutis, D. R., Weston, M. D., Alnouti, Y., Bathena, S. P., Nunn, M. E., Ogunleye, A. O., McVaney, T. P., Headen, K. V. & Miyamoto, T., May 1 2015, In : Journal of periodontology. 86, 5, p. 713-725 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

A malignant cutaneous neuroendocrine tumor with features of merkel cell carcinoma and differentiating neuroblastoma

Vanchinathan, V., Marinelli, E. C., Kartha, R. V., Uzieblo, A., Ranchod, M. & Sundram, U. N., Apr 1 2009, In : American Journal of Dermatopathology. 31, 2, p. 193-196 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

A mass spectrometric determination of the conformation of dimeric apolipoprotein A-I in discoidal high density lipoproteins

Silva, R. A. G. D., Hilliard, G. M., Li, L., Segrest, J. P. & Davidson, W. S., Jun 21 2005, In : Biochemistry. 44, 24, p. 8600-8607 8 p.

Research output: Contribution to journalArticle

92 Scopus citations

A mechanistic mathematical model of temozolomide myelosuppression in children with high-grade gliomas

Panetta, J. C., Kirstein, M. N., Gajjar, A. J., Nair, G., Fouladi, M. & Stewart, C. F., Nov 2003, In : Mathematical Biosciences. 186, 1, p. 29-41 13 p.

Research output: Contribution to journalArticle

35 Scopus citations

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11

Siddiq, A., Couch, F. J., Chen, G. K., Lindström, S., Eccles, D., Millikan, R. C., Michailidou, K., Stram, D. O., Beckmann, L., Rhie, S. K., Ambrosone, C. B., Aittomäki, K., Amiano, P., Apicella, C., Baglietto, L., Bandera, E. V., Beckmann, M. W., Berg, C. D., Bernstein, L., Blomqvist, C. & 31 others, Brauch, H., Brinton, L., Bui, Q. M., Buring, J. E., Buys, S. S., Campa, D., Carpenter, J. E., Chasman, D. I., Chang-Claude, J., Chen, C., Clavel-Chapelon, F., Cox, A., Cross, S. S., Czene, K., Deming, S. L., Diasio, R. B., Ryan Diver, W., Dunning, A. M., Durcan, L., Ekici, A. B., Fasching, P. A., Feigelson, H. S., Fejerman, L., Figueroa, J. D., Fletcher, O., Flesch-Janys, D., Gaudet, M. M., Gerty, S. M., Rodriguez-Gil, J. L., Lee, A. M. & Australian Breast Cancer Tissue Bank Investigators, 2012, In : Human molecular genetics. 21, 24, p. 5373-5384 12 p.

Research output: Contribution to journalArticle

131 Scopus citations

Amikacin pharmacokinetic-pharmacodynamic analysis in pediatric cancer patients

Alhadab, A. A., Ahmed, M. A. & Brundage, R. C., Apr 2018, In : Antimicrobial agents and chemotherapy. 62, 4, e01781-17.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Amikacin pharmacokinetics: effect of age on elimination

Rotschafer, J. C., Zaske, D. E. & Cipolle, R. J., Jan 1 1978, In : Clinical Research. 26, 3, p. 594A

Research output: Contribution to journalArticle

Amino acid grafted chitosan for high performance gene delivery: Comparison of amino acid hydrophobicity on vector and polyplex characteristics

Layek, B. & Singh, J., Feb 11 2013, In : Biomacromolecules. 14, 2, p. 485-494 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

A model-based approach to assess the exposure-response relationship of Lorenzo's oil in adrenoleukodystrophy

Ahmed, M. A., Kartha, R. V., Brundage, R. C., Cloyd, J., Basu, C., Carlin, B. P., Jones, R. O., Moser, A. B., Fatemi, A. & Raymond, G. V., Jun 1 2016, In : British Journal of Clinical Pharmacology. 81, 6, p. 1058-1066 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

A model to predict mortality following Pseudomonas aeruginosa bacteremia

Hirsch, E. B., Cottreau, J. M., Chang, K. T., Caeiro, J. P., Johnson, M. L. & Tam, V. H., Jan 1 2012, In : Diagnostic Microbiology and Infectious Disease. 72, 1, p. 97-102 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism

Sung, M. M., Zordoky, B. N., Bujak, A. L., Lally, J. S. V., Fung, D., Young, M. E., Horman, S., Miller, E. J., Light, P. E., Kemp, B. E., Steinberg, G. R. & Dyck, J. R. B., Jul 15 2015, In : Cardiovascular Research. 107, 2, p. 235-245 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation

Zordoky, B. N. M., Nagendran, J., Pulinilkunnil, T., Kienesberger, P. C., Masson, G., Waller, T. J., Kemp, B. E., Steinberg, G. R. & Dyck, J. R. B., Aug 15 2014, In : Circulation research. 115, 5, p. 518-524 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

A mucosal model to study microbial biofilm development and anti-biofilm therapeutics

Anderson, M. J., Parks, P. J. & Peterson, M. L., Feb 5 2013, In : Journal of Microbiological Methods. 92, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Analysis of 75 candidate SNPs associated with acute rejection in kidney transplant recipients: Validation of rs2910164 in MicroRNA MIR146A

Oetting, W. S., Schladt, D. P., Dorr, C. R., Wu, B., Guan, W., Remmel, R. P., Iklé, D., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Aug 1 2019, In : Transplantation. 103, 8, p. 1591-1602 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Analysis of falls in patients with epilepsy enrolled in the perampanel phase III randomized double-blind studies

Leppik, I. E., Yang, H., Williams, B., Zhou, S., Fain, R., Patten, A., Bibbiani, F. & Laurenza, A., Jan 1 2017, In : Epilepsia. 58, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
31 Scopus citations

Analysis of mouse intron 7 DNA sequence of the APP gene: Comparison with the human homologue

Li, L., Ohman, T., Deeb, S. S. & Fukuchp, K. I., Dec 1 1999, In : Mitochondrial DNA. 10, 4-5, p. 219-228 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Analysis of Mutations in the Copper B Binding Region Associated With Type I (Tyrosinase‐Related) Oculocutaneous Albinism

OETTING, WILLIAM. S. & KING, RICHARD. A., Nov 1992, In : Pigment Cell Research. 5, 5, p. 274-278 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Analysis of tyrosinase gene mutations using direct automated infrared fluorescence DNA sequencing of amplified exons

Oetting, W. S., Fryer, J. P., Oofuji, Y., Middendorf, L. R., Brumbaugh, J. A., Summers, C. G. & King, R. A., 1994, In : ELECTROPHORESIS. 15, 1, p. 159-164 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Analysis of Tyrosinase Mutations Associated With Tyrosinase‐Related Oculocutaneous Albinism (OCAI)

OETTING, WILLIAM. S. & KING, RICHARD. A., Oct 1994, In : Pigment Cell Research. 7, 5, p. 285-290 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor

Zhu, S. Z., Wang, S. Z., Hu, J. & El-Fakahany, E. E., Mar 1 1994, In : Molecular Pharmacology. 45, 3, p. 517-523 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

An artifact associated with using trypan blue exclusion to measure effects of amyloid β on neuron viability

Hu, J. & El-Fakahany, E. E., 1994, In : Life Sciences. 55, 13, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

A "new" allele at the C pigment locus in the fowl

Brumbaugh, J. A., Bargar, T. W. & Oetting, W. S., Sep 1983, In : Journal of Heredity. 74, 5, p. 331-336 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort

Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., 2018, In : Journal of lipid research. 59, 4, p. 722-729 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

An exome-wide sequencing study of the GOLDN cohort reveals novel associations of coding variants and fasting plasma lipids

Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., Jan 1 2019, In : Frontiers in Genetics. 10, feburay, 158.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
4 Scopus citations

An HIV-positive patient with epilepsy

Leppik, I. E., Gapany, S. & Walczak, T., Apr 1 2003, In : Epilepsy and Behavior. 4, SUPPL. 1, p. S17-S19

Research output: Contribution to journalArticle

2 Scopus citations

An integrated genomic approach to the assessment and treatment of acute myeloid leukemia

Godley, L. A., Cunningham, J., Dolan, M. E., Huang, R. S., Gurbuxani, S., McNerney, M. E., Larson, R. A., Leong, H., Lussier, Y., Onel, K., Odenike, O., Stock, W., White, K. P. & Le Beau, M. M., Apr 2011, In : Seminars in Oncology. 38, 2, p. 215-224 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

An in Vitro Pharmacodynamic Model to Simulate Antibiotic Behavior of Acute Otitis Media with Effusion

Vance-Bryan, K., Larson, T. A., Garrison, M. W., Toscano, J. P., Canafax, D. M. & Rotschafer, J. C., Jul 1992, In : Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 9, 7, p. 920-924 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
54 Scopus citations