Experimental and Clinical Pharmacology

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1982

Development of tolerance to PHT and CBZ detected by neuropsychological performance

Beniak, T. E., Leppik, I. E. & Bowman, T. E., Jan 1 1982, In : Epilepsia. 23, 4, p. 437-438 2 p.

Research output: Contribution to journalArticle

Drug disposition in the older adult

Brundage, R., Jan 1 1982, In : Minnesota medicine. 65, 2, p. 83-85 3 p.

Research output: Contribution to journalArticle

Gentamicin dosing errors with four commonly used nomograms

Lesar, T. S., Rotschafer, J. C., Strand, L. M., Solem, L. D. & Zaske, D. E., Oct 25 1982, In : Journal of the American Medical Association. 248, 10, p. 1190-1193 4 p.

Research output: Contribution to journalArticle

Gentamicin Dosing Errors With Four Commonly Used Nomograms

Lesar, T. S., Rotschafer, J. C., Strand, L. M., Solem, L. D. & Zaske, D. E., Sep 10 1982, In : JAMA: The Journal of the American Medical Association. 248, 10, p. 1190-1193 4 p.

Research output: Contribution to journalArticle

68 Scopus citations

Gentamicin kinetic parameters determined from radioimmunoassay (RIA) and enzyme immunoassay (EI) data

Rotschafer, J., Weaver, R., Strand, L. & Morlock, C., 1982, In : Drug Intelligence and Clinical Pharmacy. 16, 6, p. No. 58

Research output: Contribution to journalArticle

Gentamicin pharmacokinetics in 1,640 patients: Method for control of serum concentrations

Zaske, D. E., Cipolle, R. J., Rotschafer, J. C., Solem, L. D., Mosier, N. R. & Strate, R. G., Jan 1 1982, In : Unknown Journal. 21, 3, p. 407-411 5 p.

Research output: Contribution to journalArticle

119 Scopus citations

Machine detection of spike-wave activity in the EEG and its accuracy compared with visual interpretation

Whisler, J. W., ReMine, W. J., Leppik, I. E., McLain, L. W. & Gumnit, R. J., Nov 1982, In : Electroencephalography and clinical neurophysiology. 54, 5, p. 541-551 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pharmacokinetics of vancomycin: Observations in 28 patients and dosage recommendations

Rotschafer, J. C., Crossley, K. B., Zaske, D. E., Mead, K., Sawchuk, R. J. & Solem, L. D., Jan 1 1982, In : Unknown Journal. 22, 3, p. 391-394 4 p.

Research output: Contribution to journalArticle

128 Scopus citations

Phenytoin dosage predictions using population clearances

Graves, N., Cloyd, J. & Leppik, I., Jan 1 1982, In : Drug Intelligence and Clinical Pharmacy. 16, 6, p. No. 24

Research output: Contribution to journalArticle

8 Scopus citations

Phenytoin pharmacokinetics during chronic therapy

Leppik, I., Fisher, J. & Cloyd, J., Jan 1 1982, In : Neurology. 32, 4 II, p. A 223

Research output: Contribution to journalArticle

2 Scopus citations

Rapid and slow release phenytoin in epileptic patients at steady state: Assessment of relative bioavailability utilizing Michaelis-Menten parameters

Sawchuk, R. J., Pepin, S. M., Leppik, I. E. & Gumnit, R. J., Aug 1 1982, In : Journal of Pharmacokinetics and Biopharmaceutics. 10, 4, p. 383-391 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Rapid and slow release phenytoin in epileptic patients at steady state: Comparative plasma levels and toxicity

Sawchuk, R. J., Pepin, S. M., Leppik, I. E. & Gumnit, R. J., Aug 1 1982, In : Journal of Pharmacokinetics and Biopharmaceutics. 10, 4, p. 365-382 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Theophylline

Brundage, R., Dec 1 1982, In : Minnesota medicine. 65, 11, p. 713-714 2 p.

Research output: Contribution to journalArticle

Wide interpatient variations in gentamicin dose requirements for geriatric patients

Zaske, D. E., Irvine, P., Strand, L. M., Strate, R. G., Cipolle, R. J. & Rotschafer, J., Dec 1 1982, In : Journal of the American Medical Association. 248, 23, p. 3122-3126 5 p.

Research output: Contribution to journalArticle

1983

A "new" allele at the C pigment locus in the fowl

Brumbaugh, J. A., Bargar, T. W. & Oetting, W. S., Sep 1983, In : Journal of Heredity. 74, 5, p. 331-336 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Antiepileptic drug therapy. Fine tuning the dosage regimen

Welty, T. E., Graves, N. M. & Cloyd, J. C., Jan 1 1983, In : Postgraduate Medicine. 74, 5, p. 287-305 19 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bioavailability of Rectally Administered Carbamazepine Suspension in Dogs

Graves, N. M., Kriel, R. L. & Cloyd, J. C., Oct 1983, In : Epilepsia. 24, 5, p. 604-608 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clinical use of a one-compartment model for determining netilmicin pharmacokinetic parameters and dosage recommendations

Rotschafer, J. C., Crossley, K. B., Zaske, D. E., Russillo, N. J., Strate, R. G., Tofte, R. W. & Solem, L. D., Sep 1983, In : Therapeutic drug monitoring. 5, 3, p. 263-267 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Comparison of radioimmunoassay and fluorescent polarization immunoassay for quantitative determination of vancomycin concentrations in serum

Ackerman, B. H., Berg, H. G., Strate, R. G. & Rotschafer, J. C., 1983, In : Journal of clinical microbiology. 18, 4, p. 994-995 2 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Double-blind study of lorazepam and diazepam in status epilepticus

Leppik, I. E., Derivan, A. T., Homan, R. W., Walker, J., Ramsay, R. E. & Patrick, B., May 11 1983, In : Journal of the American Medical Association. 249, 11, p. 1452-1454 3 p.

Research output: Contribution to journalArticle

313 Scopus citations

Observed differences in gentamicin pharmacokinetic parameters and dosage recommendations determined by fluorescent polarization immunoassay and radioimmunoassay methods

Rotschafer, J. C., Berg, H. G., Nelson, R. B., Strand, L. & Lakatua, D. J., Dec 1983, In : Therapeutic drug monitoring. 5, 4, p. 443-447 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pharmacokinetics of valproic acid in children: I. Multiple antiepileptic drug therapy

Cloyd, J. C., Kriel, R. L., Fischer, J. H., Sawchuk, R. J. & Eggerth, R. M., Feb 1983, In : Neurology. 33, 2, p. 185-191 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Routine EEG vs. Intensive monitoring in the evaluation of intractable epilepsy

Perry, T. R., Gumnit, R. J., Gates, J. R. & Leppik, I. E., Jan 1 1983, In : Public health reports. 98, 4, p. 384-389 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

The National Traumatic Coma Data Bank. Part 1: Design, purpose, goals, and results

Marshall, L. F., Becker, D. P., Bowers, S. A., Cayard, C., Eisenberg, H., Gross, C. R., Grossman, R. G., Jane, J. A., Kunitz, S. C., Rimel, R., Tabaddor, K. & Warren, J., Jan 1 1983, In : Unknown Journal. 59, 2, p. 276-284 9 p.

Research output: Contribution to journalArticle

209 Scopus citations

Treatment of acute seizures and status epilepticus with intravenous phenytoin.

Leppik, I. E., Patrick, B. K. & Cranford, R. E., Jan 1 1983, In : Advances in neurology. 34, p. 447-451 5 p.

Research output: Contribution to journalArticle

36 Scopus citations
1984

Corpus Callosotomy: Clinical and Electroencephalographic Effects

Gates, J. R., Leppik, I. E., Yap, J. & Gumnit, R. J., Jun 1984, In : Epilepsia. 25, 3, p. 308-316 9 p.

Research output: Contribution to journalArticle

94 Scopus citations

Development of tolerance to the side effects of primidone

Leppik, I. E., Cloyd, J. C. & Miller, K., Jun 1984, In : Therapeutic drug monitoring. 6, 2, p. 189-191 3 p.

Research output: Contribution to journalArticle

14 Scopus citations

Effect of decreased renal function on the pharmacokinetics of ceftazidime

Ackerman, B. H., Ross, J., Tofte, R. W. & Rotschafer, J. C., Jan 1 1984, In : Antimicrobial agents and chemotherapy. 25, 6, p. 785-786 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Increased vancomycin dosage requirements in young burn patients

Bailie, G. R., Ackerman, B. H., Fischer, J., Solem, L. D. & Rotschafer, J. C., Jan 1 1984, In : Journal of Burn Care and Rehabilitation. 5, 5, p. 376-378 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Pain syndromes associated with cancer. Achieving effective relief

Taddeini, L. & Rotschafer, J. C., Jan 1 1984, In : Postgraduate Medicine. 75, 1, p. 101-108 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Phenytoin binding and renal transplantation

Kang, H. & Leppik, I. E., Jan 1984, In : Neurology. 34, 1, p. 83-86 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Seizures and epilepsy. Understanding the mechanisms, achieving control

Leppik, I. E., Jan 1 1984, In : Postgraduate Medicine. 75, 4, p. 229-234 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Stroke in south alabama: Incidence and diagnostic features — a population based study

Gross, C. R., Kase, C. S., Mohr, J. P., Cunningham, S. C. & Baker, W. E., Jan 1 1984, In : Stroke. 15, 2, p. 249-255 7 p.

Research output: Contribution to journalArticle

199 Scopus citations

The pilot stroke data bank: Definition, design, and data

Kunitz, S. C., Gross, C. R., Heyman, A., Kase, C. S., Mohr, J. P., Price, T. R. & Wolf, P. A., 1984, In : Stroke. 15, 4, p. 740-745 6 p.

Research output: Contribution to journalArticle

Open Access
279 Scopus citations
1985

C pigment locus mutants of the fowl produce enzymatically inactive tyrosinase‐like molecules

Oetting, W. S., Churilla, A. M., Yamamoto, H. & Brumbaugh, J. A., Aug 1985, In : Journal of Experimental Zoology. 235, 2, p. 237-245 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Detection of melanogenic proteins in cultured chick-embryo melanocytes

Oetting, W., Langner, K. & Brumbaugh, J. A., Jan 1 1985, In : Differentiation. 30, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Interobserver Variability in the Assessment of Neurologic History and Examination in the Stroke Data Bank

Shinar, D., Gross, C. R., Mohr, J. P., Caplan, L. R., Price, T. R., Wolf, P. A., Hier, D. B., Kase, C. S., Fishman, I. G., Wolf, C. L. & Kunitz, S. C., Jun 1985, In : Archives of Neurology. 42, 6, p. 557-565 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Intracellular processing of prolactin

Oetting, W. S. & Walker, A. M., Oct 1985, In : Endocrinology. 117, 4, p. 1565-1570 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Intracellular processing of prolactin (PRL)

Oetting, W. S. & Walker, A. M., Jan 1 1985, In : Federation Proceedings. 44, 3, p. No. 1291

Research output: Contribution to journalArticle

Paul F. Parker's impact on pharmacy education.

Cloyd, J. C., Sep 1 1985, In : American Journal of Hospital Pharmacy. 42, 9, p. 2018-2022 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Relative Bioavailability of Rectally Administered Carbamazepine Suspension in Humans

Graves, N. M., Kriel, R. L., Jones‐Saete, C. & Cloyd, J. C., Oct 1985, In : Epilepsia. 26, 5, p. 429-433 5 p.

Research output: Contribution to journalArticle

42 Scopus citations

Seasonal Incidence of Phenytoin Allergy Unrelated to Plasma Levels

Leppik, I. E., Lapora, J. & Loewenson, R., Feb 1985, In : Archives of Neurology. 42, 2, p. 120-122 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Status epilepticus

Leppik, I. E., Jan 1 1985, In : Clinical Therapeutics. 7, 2, p. 272-278 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Valproate and Clonazepam Comedication in Patients with Intractable Epilepsy

Mirelesh, R. & Leppik, I. E., Apr 1985, In : Epilepsia. 26, 2, p. 122-126 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

Valproic acid pharmacokinetics in children. II. Discontinuation of concomitant antiepileptic drug therapy

Cloyd, J. C., Kriel, R. L. & Fischer, J. H., Nov 1985, In : Neurology. 35, 11, p. 1623-1627 5 p.

Research output: Contribution to journalArticle

36 Scopus citations
1986

Altered phenytoin clearance with febrile illness

Leppik, I. E., Fisher, J., Kriel, R. & Sawchuk, R. J., Oct 1986, In : Neurology. 36, 10, p. 1367-1370 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Differential isoform distribution between stored and secreted prolactin

Oetting, W. S. & Walker, A. M., Sep 1986, In : Endocrinology. 119, 3, p. 1377-1381 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Double‐Blind Withdrawal of Phenytoin and Carbamazepine in Patients Treated with Progabide for Partial Seizures

Leppik, I. E., Brundage, R., Krall, R., Cloyd, J. C., Bowman‐Cloyd, T. & Jacobs, M. P., Oct 1986, In : Epilepsia. 27, 5, p. 563-568 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Eating Epilepsy: EEG and Clinical Study

Fiol, M. E., Leppik, I. E. & Pretzel, K., Aug 1986, In : Epilepsia. 27, 4, p. 441-445 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Interobserver Agreement in the Diagnosis of Stroke Type

Gross, C. R., Shinar, D., Mohr, J. P., Hier, D. B., Caplan, L. R., Price, T. R., Wolf, P. A., Kase, C. S., Fishman, I. G., Calingo, S. & Kunitz, S. C., Sep 1986, In : Archives of Neurology. 43, 9, p. 893-898 6 p.

Research output: Contribution to journalArticle

47 Scopus citations