Experimental and Clinical Pharmacology

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2019

Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy

Birnbaum, A. K., Karanam, A., Marino, S. E., Barkley, C. M., Remmel, R. P., Roslawski, M., Gramling-Aden, M. & Leppik, I. E., Jan 1 2019, In : Epilepsia. 60, 8, p. 1586-1592 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Baruffaldi, F., Raleigh, M. D., King, S. J., Roslawski, M. J., Birnbaum, A. K., Hassler, C., Carroll, F. I., Runyon, S. P., Winston, S., Pentel, P. R. & Pravetoni, M., Jun 3 2019, In : Molecular pharmaceutics. 16, 6, p. 2364-2375 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion

Alharbi, A. F., Kratzke, R. A., D’Cunha, J., Maddaus, M. A., Sanghavi, K. & Kirstein, M. N., Feb 5 2019, In : Cancer chemotherapy and pharmacology. 83, 2, p. 387-391 5 p.

Research output: Contribution to journalArticle

Open Access

Genetic variants associated with immunosuppressant pharmacokinetics and adverse effects in the DeKAF genomics genome-wide association studies

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Van Setten, J., Keating, B. J., Iklé, D., Remmel, R. P., Dorr, C. R., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Jun 1 2019, In : Transplantation. 103, 6, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Human cerebrospinal fluid 6E10- immunoreactive protein species contain amyloid precursor protein fragments

Grant, M. K. O., Handoko, M., Rozga, M., Brinkmalm, G., Portelius, E., Blennow, K., Ashe, K. H., Zahs, K. R. & Liu, P., Feb 2019, In : PloS one. 14, 2, e0212815.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
3 Scopus citations

Improving payload capacity and anti-tumor efficacy of mesenchymal stem cells using tat peptide functionalized polymeric nanoparticles

Moku, G., Layek, B., Trautman, L., Putnam, S., Panyam, J. & Prabha, S., Apr 2019, In : Cancers. 11, 4, 491.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Interprofessional education within a pilot HIV-care elective course

Pittenger, A. L., Goodroad, B., Nicol, M., Durgin, E. N., Eveland, L., Kaiser, R., Benbenek, M., Benson, N. R. & Rybicki, S., Dec 2019, In : American journal of pharmaceutical education. 83, 10, p. 2053-2058 6 p., 7402.

Research output: Contribution to journalArticle

Intranasal coadministration of a diazepam prodrug with a converting enzyme results in rapid absorption of diazepam in rats

Rautiola, D., Maglalang, P. D., Cheryala, N., Nelson, K. M., Georg, G. I., Fine, J. M., Svitak, A. L., Faltesek, K. A., Hanson, L. R., Mishra, U., Coles, L. D., Cloyd, J. C. & Siegel, R. A., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 3, p. 796-805 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Lessons from the Established Status Epilepticus Treatment Trial

Cock, H. R., Coles, L. D., Elm, J., Silbergleit, R., Chamberlain, J. M., Cloyd, J. C., Fountain, N., Shinnar, S., Lowenstein, D., Conwit, R., Bleck, T. P. & Kapur, J., Jan 1 2019, (Accepted/In press) In : Epilepsy and Behavior. 106296.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
2 Scopus citations

Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing

on behalf of the IGNITE Network, Oct 1 2019, In : Genetics in Medicine. 21, 10, p. 2255-2263 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
Open Access
2 Scopus citations

Neurochemical abnormalities in patients with type 1 Gaucher disease on standard of care therapy

Kartha, R. V., Joers, J., Terluk, M. R., Travis, A., Rudser, K., Tuite, P. J., Weinreb, N. J., Jarnes, J. R., Cloyd, J. C. & Öz, G., Jan 1 2019, (Accepted/In press) In : Journal of Inherited Metabolic Disease.

Research output: Contribution to journalArticle

1 Scopus citations

NRXN1 is associated with enlargement of the temporal horns of the lateral ventricles in psychosis

Alliey-Rodriguez, N., Grey, T. A., Shafee, R., Asif, H., Lutz, O., Bolo, N. R., Padmanabhan, J., Tandon, N., Klinger, M., Reis, K., Spring, J., Coppes, L., Zeng, V., Hegde, R. R., Hoang, D. T., Bannai, D., Nawaz, U., Henson, P., Liu, S., Gage, D. & 21 others, McCarroll, S., Bishop, J. R., Hill, S., Reilly, J. L., Lencer, R., Clementz, B. A., Buckley, P., Glahn, D. C., Meda, S. A., Narayanan, B., Pearlson, G., Keshavan, M. S., Ivleva, E. I., Tamminga, C., Sweeney, J. A., Curtis, D., Badner, J. A., Keedy, S., Rapoport, J., Liu, C. & Gershon, E. S., Dec 1 2019, In : Translational psychiatry. 9, 1, 230.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Once-monthly subcutaneously administered risperidone in the treatment of schizophrenia: Patient considerations

Tchobaniouk, L. V., McAllister, E. E., Bishop, D. L., Carpentier, R. M., Heins, K. R., Haight, R. J. & Bishop, J. R., Jan 1 2019, In : Patient Preference and Adherence. 13, p. 2233-2241 9 p.

Research output: Contribution to journalArticle

Open Access

Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis

ASTRO-CM Study Team, Dec 1 2019, In : Journal of Pharmacokinetics and Pharmacodynamics. 46, 6, p. 565-576 12 p.

Research output: Contribution to journalArticle

Pharmacy education needs to address diagnostic safety

Graber, M. L., Grice, G. R., Ling, L. J., Conway, J. M. & Olson, A., Jan 1 2019, In : American journal of pharmaceutical education. 83, 6, p. 1179-1188 10 p., 7442.

Research output: Contribution to journalArticle

Portal Vein Thrombosis after Total Pancreatectomy and Islet Autotransplant: Prophylaxis and Graft Impact

Robbins, A. J., Skube, M. E., Bellin, M. D., Dunn, T. B., Chapman, S. A., Berry, K. L., Lusczek, E. & Beilman, G. J., Nov 1 2019, In : Pancreas. 48, 10, p. 1329-1333 5 p.

Research output: Contribution to journalArticle

Preclinical evaluation of an unconventional ruthenium-gold-based chemotherapeutic: RANCE-1, in clear cell renal cell carcinoma

Elie, B. T., Hubbard, K., Pechenyy, Y., Layek, B., Prabha, S. & Contel, M., Jan 1 2019, In : Cancer medicine. 8, 9, p. 4304-4314 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Randomized trial of three anticonvulsant medications for status epilepticus

NETT and PECARN Investigators, Nov 28 2019, In : New England Journal of Medicine. 381, 22, p. 2103-2113 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Reiki for Pain During Hemodialysis: A Feasibility and Instrument Evaluation Study

Zins, S., Hooke, M. C. & Gross, C. R., Jun 1 2019, In : Journal of Holistic Nursing. 37, 2, p. 148-162 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice

Grant, M. K. O., Seelig, D. M., Sharkey, L. C., Choi, W. S. V., Abdelgawad, I. Y. & Zordoky, B. N., Feb 2019, In : PloS one. 14, 2, e0212486.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
4 Scopus citations

Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups

the DeKAF Genomics and GEN03 Investigators, Oct 1 2019, In : American Journal of Transplantation. 19, 10, p. 2795-2804 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population

The UK Ireland Renal Transplant Consortium, DeKAF Genomics and GEN03 Studies & The International Genetics and Translational Research in Transplantation Network, Aug 2019, In : American Journal of Transplantation. 19, 8, p. 2262-2273 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

The nonconservative CD177 single-nucleotide polymorphism c.1291G>A is a genetic determinant for human neutrophil antigen-2 atypical/low expression and deficiency

Wu, J., Li, Y., Schuller, R. M., Li, L., Litmeyer, A. S., Bein, G., Sachs, U. J. & Bayat, B., May 2019, In : Transfusion. 59, 5, p. 1836-1842 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Use of herbal medicine by pregnant women: What physicians need to know

Illamola, S. M., Amaeze, O. U., Krepkova, L. V., Birnbaum, A. K., Karanam, A., Job, K. M., Bortnikova, V. V., Sherwin, C. M. T. & Enioutina, E. Y., Jan 1 2019, In : Frontiers in Pharmacology. 10, 1483.

Research output: Contribution to journalArticle

Open Access

Working Memory Capacity Is Negatively Associated with Memory Load Modulation of Alpha Oscillations in Retention of Verbal Working Memory

Hu, Z., Barkley, C. M., Marino, S. E., Wang, C., Rajan, A., Bo, K., Samuel, I. B. H. & Ding, M., Dec 1 2019, In : Journal of cognitive neuroscience. 31, 12, p. 1933-1945 13 p.

Research output: Contribution to journalArticle

2018

A Holistic Clustering Methodology for Liver Transplantation Survival

Pruinelli, L., Simon, G. J., Monsen, K. A., Pruett, T. L., Gross, C. R., Radosevich, D. M. & Westra, B. L., Jul 1 2018, In : Nursing research. 67, 4, p. 331-340 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Alpha-toxin contributes to biofilm formation among Staphylococcus aureus wound isolates

Anderson, M. J., Schaaf, E., Breshears, L. M., Wallis, H. W., Johnson, J. R., Tkaczyk, C., Sellman, B. R., Sun, J. & Peterson, M. L., Apr 2018, In : Toxins. 10, 4, 157.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Amikacin pharmacokinetic-pharmacodynamic analysis in pediatric cancer patients

Alhadab, A. A., Ahmed, M. A. & Brundage, R. C., Apr 2018, In : Antimicrobial agents and chemotherapy. 62, 4, e01781-17.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort

Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., Jan 1 2018, In : Journal of Lipid Research. 59, 4, p. 722-729 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Anticancer effects of resveratrol in canine hemangiosarcoma cell lines

Carlson, A., Alderete, K. S., Grant, M. K. O., Seelig, D. M., Sharkey, L. C. & Zordoky, B. N. M., Jun 2018, In : Veterinary and Comparative Oncology. 16, 2, p. 253-261 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Remmel, R. P., Dorr, C., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Feb 2018, In : Pharmacogenomics. 19, 3, p. 175-184 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Beneficial and adverse effects of antipsychotic medication on cognitive flexibility are related to COMT genotype in first episode psychosis

Nelson, C. L. M., Amsbaugh, H. M., Reilly, J. L., Rosen, C., Marvin, R. W., Ragozzino, M. E., Bishop, J. R., Sweeney, J. A. & Hill, S. K., Dec 2018, In : Schizophrenia Research. 202, p. 212-216 5 p.

Research output: Contribution to journalArticle

Brain’s compensatory response to drug-induced cognitive impairment

Babu Henry Samuel, I., Barkley, C., Marino, S. E., Wang, C., Han, S. M., Birnbaum, A. K., Cibula, J. E. & Ding, M., Nov 26 2018, In : Journal of Clinical and Experimental Neuropsychology. 40, 10, p. 1000-1012 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cancer expression quantitative trait loci (eQTLs) can be determined from heterogeneous tumor gene expression data by modeling variation in tumor purity

Geeleher, P., Nath, A., Wang, F., Zhang, Z., Barbeira, A. N., Fessler, J., Grossman, R. L., Seoighe, C. & Stephanie Huang, R., Sep 11 2018, In : Genome biology. 19, 1, 130.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Co-administration of resveratrol with doxorubicin in youngmice attenuates detrimental late-occurring cardiovascular changes

Matsumura, N., Zordoky, B. N., Robertson, I. M., Hamza, S. M., Parajuli, N., Soltys, C. M., Beker, D. L., Grant, M. K., Razzoli, M., Bartolomucci, A. & Dyck, J. R. B., Aug 1 2018, In : Cardiovascular Research. 114, 10, p. 1350-1359 10 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Cognitive burden of common non-antiretroviral medications in HIV-infected women

Rubin, L. H., Radtke, K. K., Eum, S., Tamraz, B., Kumanan, K. N., Springer, G., Maki, P. M., Anastos, K., Merenstein, D., Karim, R., Weber, K. M., Gustafson, D., Greenblatt, R. M. & Bishop, J. R., Sep 1 2018, In : Journal of Acquired Immune Deficiency Syndromes. 79, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
4 Scopus citations

Detection of high-risk carbapenem-resistant Klebsiella pneumoniae and Enterobacter cloacae isolates using volatile molecular profiles

Rees, C. A., Nasir, M., Smolinska, A., Lewis, A. E., Kane, K. R., Kossmann, S. E., Sezer, O., Zucchi, P. C., Doi, Y., Hirsch, E. B. & Hill, J. E., Dec 1 2018, In : Scientific reports. 8, 1, 13297.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Deviation from expected cognitive ability across psychotic disorders

Hochberger, W. C., Combs, T., Reilly, J. L., Bishop, J. R., Keefe, R. S. E., Clementz, B. A., Keshavan, M. S., Pearlson, G. D., Tamminga, C. A., Hill, S. K. & Sweeney, J. A., Feb 2018, In : Schizophrenia Research. 192, p. 300-307 8 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Economic Evaluation of a Patient-Directed Music Intervention for ICU Patients Receiving Mechanical Ventilatory Support

Chlan, L. L., Heiderscheit, A., Skaar, D. J. & Neidecker, M. V., Jan 1 2018, In : Critical care medicine. 46, 9, p. 1430-1435 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effects of smoking and paroxetine on stress-induced craving and withdrawal symptoms

Kotlyar, M., Chau, H. T. & Thuras, P., Nov 2 2018, In : Journal of Substance Use. 23, 6, p. 655-659 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
5 Scopus citations

Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model

Bilal, H., Peleg, A. Y., McIntosh, M. P., Styles, I. K., Hirsch, E. B., Landersdorfer, C. B. & Bergen, P. J., Jun 1 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1570-1578 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

Isakson, S. H., Rizzardi, A. E., Coutts, A. W., Carlson, D. F., Kirstein, M. N., Fisher, J., Vitte, J., Williams, K. B., Pluhar, G. E., Dahiya, S., Widemann, B. C., Dombi, E., Rizvi, T., Ratner, N., Messiaen, L., Stemmer-Rachamimov, A. O., Fahrenkrug, S. C., Gutmann, D. H., Giovannini, M., Moertel, C. L. & 2 others, Largaespada, D. A. & Watson, A. L., Dec 1 2018, In : Communications biology. 1, 1, 158.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations