Experimental and Clinical Pharmacology

Research Output

Filter
Article
2020

Antiepileptic Drug Exposure in Infants of Breastfeeding Mothers with Epilepsy

Birnbaum, A. K., Meador, K. J., Karanam, A., Brown, C., May, R. C., Gerard, E. E., Gedzelman, E. R., Penovich, P. E., Kalayjian, L. A., Cavitt, J., Pack, A. M., Miller, J. W., Stowe, Z. N. & Pennell, P. B., Apr 2020, In : JAMA Neurology. 77, 4, p. 441-450 10 p.

Research output: Contribution to journalArticle

A phase I dose finding study of intravenous voriconazole in pediatric patients undergoing hematopoietic cell transplantation

Knight-Perry, J., Jennissen, C., Long, S. E., Hage, S., DeFor, T. E., Chan, W. T., Fisher, J., Kirstein, M. N. & Smith, A. R., May 1 2020, In : Bone marrow transplantation. 55, 5, p. 955-964 10 p.

Research output: Contribution to journalArticle

Assessment of mortality stratified by meropenem minimum inhibitory concentration in patients with Enterobacteriaceae bacteraemia: A patient-level analysis of published data

O'Donnell, J. N., Rhodes, N. J., Biehle, L. R., Esterly, J. S., Patel, T. S., McLaughlin, M. M. & Hirsch, E. B., Feb 2020, In : International Journal of Antimicrobial Agents. 55, 2, 105849.

Research output: Contribution to journalArticle

Brain gray matter network organization in psychotic disorders

Zhang, W., Lei, D., Keedy, S. K., Ivleva, E. I., Eum, S., Yao, L., Tamminga, C. A., Clementz, B. A., Keshavan, M. S., Pearlson, G. D., Gershon, E. S., Bishop, J. R., Gong, Q., Lui, S. & Sweeney, J. A., Mar 1 2020, In : Neuropsychopharmacology. 45, 4, p. 666-674 9 p.

Research output: Contribution to journalArticle

Open Access

Determination of Rate and Extent of Scopolamine Release from Transderm Scōp® Transdermal Drug Delivery Systems in Healthy Human Adults

Swaminathan, S. K., Strasinger, C., Kelchen, M., Carr, J., Ye, W., Wokovich, A., Ghosh, P., Rajagopal, S., Ueda, K., Fisher, J., Kandimalla, K. K. & Brogden, N. K., Apr 1 2020, In : AAPS PharmSciTech. 21, 3, 117.

Research output: Contribution to journalArticle

Effect of nicotine lozenge use prior to smoking cue presentation on craving and withdrawal symptom severity

Kotlyar, M., Vogel, R. I., Dufresne, S. R., Mills, A. M. & Vuchetich, J. P., Jan 1 2020, In : Drug and alcohol dependence. 206, 107706.

Research output: Contribution to journalArticle

Open Access

Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial

Neurological Emergencies Treatment Trials, Apr 11 2020, In : The Lancet. 395, 10231, p. 1217-1224 8 p.

Research output: Contribution to journalArticle

Open Access

Emerging role of long non-coding RNAs in cancer precision medicine

Nath, A. & Huang, R. S., Jan 2 2020, In : Molecular and Cellular Oncology. 7, 1, 1684130.

Research output: Contribution to journalArticle

Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Rybak, M. J., Le, J., Lodise, T. P., Levine, D. P., Bradley, J. S., Liu, C., Mueller, B. A., Pai, M. P., Wong-Beringer, A., Rotschafer, J. C., Rodvold, K. A., Maples, H. D. & Lomaestro, B. M., Apr 1 2020, In : Pharmacotherapy. 40, 4, p. 363-367 5 p.

Research output: Contribution to journalArticle

Open Access
Open Access
Open Access

HLA-B∗58:01 carrier status of Hmong in Minnesota: First in Hmong genotyping for prevalence of this biomarker of risk for severe cutaneous adverse reactions caused by allopurinol

Peng, K., Bjork, J., Wen, Y. F., Roman, Y. M., Culhane-Pera, K., Lo, M. X., Gertner, E. & Straka, R. J., Feb 1 2020, In : Pharmacogenetics and genomics. p. 21-25 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

iMIRAGE: an R package to impute microRNA expression using protein-coding genes

Nath, A., Chang, J. & Huang, R. S., Apr 15 2020, In : Bioinformatics (Oxford, England). 36, 8, p. 2608-2610 3 p.

Research output: Contribution to journalArticle

Open Access

Long non-coding RNA transcriptome of uncharacterized samples can be accurately imputed using protein-coding genes

Nath, A., Geeleher, P. & Huang, R. S., Mar 23 2020, In : Briefings in Bioinformatics. 21, 2, p. 637-648 12 p.

Research output: Contribution to journalArticle

PharmGKB summary: Lamotrigine pathway, pharmacokinetics and pharmacodynamics

Mitra-Ghosh, T., Callisto, S. P., Lamba, J. K., Remmel, R. P., Birnbaum, A. K., Barbarino, J. M., Klein, T. E. & Altman, R. B., Jan 1 2020, (Accepted/In press) In : Pharmacogenetics and genomics. p. 81-90 10 p.

Research output: Contribution to journalArticle

Potential Clinical Relevance of Differences in Allele Frequencies Found within Very Important Pharmacogenes between Hmong and East Asian Populations

Wen, Y. F., Culhane-Pera, K. A., Thyagarajan, B., Bishop, J. R., Zierhut, H., Lo, M., Xiong, T., Peng, K., Holzer, K., Lee, K. & Straka, R. J., Feb 1 2020, In : Pharmacotherapy. 40, 2, p. 142-152 11 p.

Research output: Contribution to journalArticle

Relationships between the nicotine metabolite ratio and a panel of exposure and effect biomarkers: Findings from two studies of U.S. commercial cigarette smokers

Carroll, D. M., Murphy, S. E., Benowitz, N. L., Strasser, A. A., Kotlyar, M., Hecht, S. S., Carmella, S. G., McClernon, F. J., Pacek, L. R., Dermody, S. S., Vandrey, R. G., Donny, E. C. & Hatsukami, D. K., Jan 1 2020, In : Cancer Epidemiology Biomarkers and Prevention. 29, 4, p. 871-879 9 p.

Research output: Contribution to journalArticle

Open Access
Open Access
2019

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

ASTRO-CM Team, Aug 2019, In : The Lancet Infectious Diseases. 19, 8, p. 843-851 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

A Gallbladder-Based Enterohepatic Circulation Model for Pharmacokinetic Studies

Okour, M. & Brundage, R. C., Aug 1 2019, In : European Journal of Drug Metabolism and Pharmacokinetics. 44, 4, p. 493-504 12 p.

Research output: Contribution to journalArticle

Analysis of 75 candidate SNPs associated with acute rejection in kidney transplant recipients: Validation of rs2910164 in MicroRNA MIR146A

Oetting, W. S., Schladt, D. P., Dorr, C. R., Wu, B., Guan, W., Remmel, R. P., Iklé, D., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Aug 1 2019, In : Transplantation. 103, 8, p. 1591-1602 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

An exome-wide sequencing study of the GOLDN cohort reveals novel associations of coding variants and fasting plasma lipids

Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., Jan 1 2019, In : Frontiers in Genetics. 10, feburay, 158.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A Novel Research Method for Determining Sedative Exposure in Critically Ill Patients

Tracy, M. F., Chlan, L., Savik, K., Skaar, D. J. & Weinert, C. R., Jan 1 2019, In : Nursing research. 68, 1, p. 73-79 7 p., 00322.

Research output: Contribution to journalArticle

Open Access

Apolipoprotein A-I crosses the blood-brain barrier through clathrin-independent and cholesterol-mediated endocytosis

Zhou, A. L., Swaminathan, S. K., Curran, G. L., Poduslo, J. F., Lowe, V. J., Li, L. & Kandimalla, K. K., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 369, 3, p. 481-488 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Association of choroid plexus enlargement with cognitive, inflammatory, and structural phenotypes across the psychosis spectrum

Lizano, P., Lutz, O., Ling, G., Lee, A. M., Eum, S., Bishop, J. R., Kelly, S., Pasternak, O., Clementz, B., Pearlson, G., Sweeney, J. A., Gershon, E., Tamminga, C. & Keshavan, M., Jan 1 2019, In : American Journal of Psychiatry. 176, 7, p. 564-572 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Brain distributional kinetics of a novel MDM2 inhibitor SAR405838: Implications for use in brain tumor therapy

Kim, M., Laramy, J. K., Gampa, G., Parrish, K. E., Brundage, R., Sarkaria, J. N. & Elmquist, W. F., Jan 1 2019, In : Drug Metabolism and Disposition. 47, 12, p. 1403-1414 12 p.

Research output: Contribution to journalArticle

Brain distribution of a panel of epidermal growth factor receptor inhibitors using cassette dosing in wild-type and ABCB1/ABCG2-deficient mice

Kim, M., Laramy, J. K., Mohammad, A. S., Talele, S., Fisher, J., Sarkaria, J. N. & Elmquist, W. F., Apr 2019, In : Drug Metabolism and Disposition. 47, 4, p. 393-404 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Case report: Three's a crowd: A case report examining the diagnostic and pharmacokinetic challenges in hiv-tuberculous meningitis-malaria co-infection [version 2; referees: 2 approved]

Ellis, J., Eneh, P. C., Ssebambulidde, K., Rutakingirwa, M. K., Lamorde, M., Rhein, J., Cresswell, F. V., Boulware, D. R. & Nicol, M. R., Jan 1 2019, In : Wellcome Open Research. 3, 111.

Research output: Contribution to journalArticle

Open Access

Cerebrospinal Fluid and Brain Tissue Penetration of Tenofovir, Lamivudine, and Efavirenz in Postmortem Tissues with Cryptococcal Meningitis

Nicol, M. R., Pastick, K. A., Taylor, J., Namuju, O. C., Rhein, J., Williams, D. A., Meya, D. B., Boulware, D. R. & Lukande, R., Sep 1 2019, In : Clinical and translational science. 12, 5, p. 445-449 5 p.

Research output: Contribution to journalArticle

Open Access

Closing the classroom theory to practice gap by simulating a psychiatric pharmacy practice experience

Pittenger, A. L., Dimitropoulos, E., Foag, J., Bishop, D., Panizza, S. & Bishop, J. R., Dec 2019, In : American journal of pharmaceutical education. 83, 10, 7276.

Research output: Contribution to journalArticle

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

AstraZeneca-Sanger Drug Combination DREAM Consortium, Dec 1 2019, In : Nature communications. 10, 1, 2674.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
1 Scopus citations

Consensus Clinical Decision-Making Factors Driving Anticoagulation in Atrial Fibrillation

King, P. K., Fosnight, S. M. & Bishop, J. R., Oct 1 2019, In : American Journal of Cardiology. 124, 7, p. 1038-1043 6 p.

Research output: Contribution to journalArticle

Design, Development, and Characterization of Imiquimod-Loaded Chitosan Films for Topical Delivery

Layek, B., Rahman Nirzhor, S. S., Rathi, S., Kandimalla, K. K., Wiedmann, T. S. & Prabha, S., Feb 1 2019, In : AAPS PharmSciTech. 20, 2, 58.

Research output: Contribution to journalArticle

2 Scopus citations

Development and validation of a sensitive LC-MS/MS method for the estimation of scopolamine in human serum

Swaminathan, S. K., Fisher, J., Brogden, N. K. & Kandimalla, K. K., Feb 5 2019, In : Journal of Pharmaceutical and Biomedical Analysis. 164, p. 41-46 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes

Nath, A., Lau, E. Y. T., Lee, A. M., Geeleher, P., Cho, W. C. S. & Huang, R. S., Oct 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22020-22029 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Does the beta-lactam matter? Nafcillin versus cefazolin for methicillin-susceptible staphylococcus aureus bloodstream infections

Burrelli, C. C., Broadbent, E. K., Margulis, A., Snyder, G. M., Gold, H. S., McCoy, C., Mahoney, M. V. & Hirsch, E. B., Apr 1 2019, In : Chemotherapy. 63, 6, p. 345-351 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effects of Very Low Nicotine Content Cigarettes on Smoking Behavior and Biomarkers of Exposure in Menthol and Non-menthol Smokers

Denlinger-Apte, R. L., Kotlyar, M., Koopmeiners, J. S., Tidey, J. W., Luo, X., Benowitz, N. L., Jensen, J. A., Ikuemonisan, J. O., Pacek, L. R., Smith, T. T., Vandrey, R., Donny, E. C. & Hatsukami, D. K., Dec 23 2019, In : Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 21, 1, p. S63-S72

Research output: Contribution to journalArticle

Open Access

Emergence of the Ug99 lineage of the wheat stem rust pathogen through somatic hybridisation

Li, F., Upadhyaya, N. M., Sperschneider, J., Matny, O., Nguyen-Phuc, H., Mago, R., Raley, C., Miller, M. E., Silverstein, K. A. T., Henningsen, E., Hirsch, C. D., Visser, B., Pretorius, Z. A., Steffenson, B. J., Schwessinger, B., Dodds, P. N. & Figueroa, M., Dec 1 2019, In : Nature communications. 10, 1, 5068.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Engineered mesenchymal stem cells for targeting solid tumors: Therapeutic potential beyond regenerative therapy

Cheng, S., Nethi, S. K., Rathi, S., Layek, B. & Prabha, S., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 2, p. 231-241 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy

Birnbaum, A. K., Karanam, A., Marino, S. E., Barkley, C. M., Remmel, R. P., Roslawski, M., Gramling-Aden, M. & Leppik, I. E., Jan 1 2019, In : Epilepsia. 60, 8, p. 1586-1592 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Formulation and Characterization of Conjugate Vaccines to Reduce Opioid Use Disorders Suitable for Pharmaceutical Manufacturing and Clinical Evaluation

Baruffaldi, F., Raleigh, M. D., King, S. J., Roslawski, M. J., Birnbaum, A. K., Hassler, C., Carroll, F. I., Runyon, S. P., Winston, S., Pentel, P. R. & Pravetoni, M., Jun 3 2019, In : Molecular pharmaceutics. 16, 6, p. 2364-2375 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion

Alharbi, A. F., Kratzke, R. A., D’Cunha, J., Maddaus, M. A., Sanghavi, K. & Kirstein, M. N., Feb 5 2019, In : Cancer chemotherapy and pharmacology. 83, 2, p. 387-391 5 p.

Research output: Contribution to journalArticle