Experimental and Clinical Pharmacology

Research Output

2014

USL255 extended-release topiramate: Dose-proportional pharmacokinetics and tolerability in healthy volunteers

Clark, A. M., Halvorsen, M. B., Braun, T. L., Johnson, K. M. & Cloyd, J. C., Jul 2014, In : Epilepsia. 55, 7, p. 1069-1076 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Vaccination against staphylococcus aureus pneumonia

Spaulding, A. R., Salgado-Pabón, W., Merriman, J. A., Stach, C. S., Ji, Y., Gillman, A. N., Peterson, M. L. & Schlievert, P. M., Jun 15 2014, In : Journal of Infectious Diseases. 209, 12, p. 1955-1962 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

α(2A) adrenergic receptor promotes amyloidogenesis through disrupting APP-SorLA interaction

Chen, Y., Peng, Y., Che, P., Gannon, M., Liu, Y., Li, L., Bu, G., van Groen, T., Jiao, K. & Wang, Q., Dec 2 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 48, p. 17296-17301 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013

Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

Anwar-Mohamed, A., El-Sherbeni, A., Kim, S. H., Elshenawy, O. H., Althurwi, H. N., Zordoky, B. N. M. & El-Kadi, A. O. S., Aug 1 2013, In : Xenobiotica. 43, 8, p. 719-729 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

A DPYD variant (Y186C) in individuals of african ancestry is associated with reduced DPD enzyme activity

Offer, S. M., Lee, A. M., Mattison, L. K., Fossum, C., Wegner, N. J. & Diasio, R. B., Jul 1 2013, In : Clinical pharmacology and therapeutics. 94, 1, p. 158-166 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

A genome-wide association study of behavioral disinhibition

Mc Gue, M., Zhang, Y., Miller, M. B., Basu, S., Vrieze, S. I., Hicks, B., Malone, S., Oetting, W. S. & Iacono, W. G., Aug 14 2013, In : Behavior genetics. 43, 5, p. 363-373 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

A genome-wide integrative study of microRNAs in human liver

Gamazon, E. R., Innocenti, F., Wei, R., Wang, L., Zhang, M., Mirkov, S., Ramírez, J., Huang, R. S., Cox, N. J., Ratain, M. J. & Liu, W., Jun 13 2013, In : BMC Genomics. 14, 1, 395.

Research output: Contribution to journalArticle

25 Scopus citations

Amino acid grafted chitosan for high performance gene delivery: Comparison of amino acid hydrophobicity on vector and polyplex characteristics

Layek, B. & Singh, J., Feb 11 2013, In : Biomacromolecules. 14, 2, p. 485-494 10 p.

Research output: Contribution to journalArticle

56 Scopus citations

A mucosal model to study microbial biofilm development and anti-biofilm therapeutics

Anderson, M. J., Parks, P. J. & Peterson, M. L., Feb 5 2013, In : Journal of Microbiological Methods. 92, 2, p. 201-208 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers

Agarwal, S. K., Kriel, R. L., Brundage, R., Ivaturi, V. D. & Cloyd, J. C., Aug 1 2013, In : Epilepsy Research. 105, 3, p. 362-367 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Apolipoprotein A5 gene variants and the risk ofcoronary heart disease: A case-control study and meta-analysis

Zhou, J., Xu, L., Huang, R. S., Huang, Y., Le, Y., Jiang, D., Yang, X., Xu, W., Huang, X., Dong, C., Ye, M., Lian, J. & Duan, S., Oct 2013, In : Molecular medicine reports. 8, 4, p. 1175-1182 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Assessment of antimicrobial combinations for Klebsiella pneumoniae carbapenemase-producing K. pneumoniae

Hirsch, E. B., Guo, B., Chang, K. T., Cao, H., Ledesma, K. R., Singh, M. & Tam, V. H., Mar 1 2013, In : Journal of Infectious Diseases. 207, 5, p. 786-793 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
6 Scopus citations

Association between respiratory sinus arrhythmia and reductions in startle responding in three independent samples

Gorka, S. M., McGowan, S. K., Campbell, M. L., Nelson, B. D., Sarapas, C., Bishop, J. R. & Shankman, S. A., May 1 2013, In : Biological Psychology. 93, 2, p. 334-341 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
52 Scopus citations

Bioavailability of Intranasal vs. Rectal Diazepam

Ivaturi, V., Kriel, R., Brundage, R., Loewen, G., Mansbach, H. & Cloyd, J. C., Feb 1 2013, In : Epilepsy Research. 103, 2-3, p. 254-261 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice

Dolinsky, V. W., Rogan, K. J., Sung, M. M., Zordoky, B. N., Haykowsky, M. J., Young, M. E., Jones, L. W. & Dyck, J. R. B., Jul 15 2013, In : American Journal of Physiology - Endocrinology and Metabolism. 305, 2, p. E243-E253

Research output: Contribution to journalArticle

69 Scopus citations

Caproic acid grafted chitosan cationic nanocomplexes for enhanced gene delivery: Effect of degree of substitution

Layek, B. & Singh, J., Apr 15 2013, In : International journal of pharmaceutics. 447, 1-2, p. 182-191 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cardiomyocyte specific adipose triglyceride lipase overexpression prevents doxorubicin induced cardiac dysfunction in female mice

Nagendran, J., Kienesberger, P. C., Pulinilkunnil, T., Zordoky, B. N., Sung, M. M., Kim, T., Young, M. E. & Dyck, J. R. B., Jul 1 2013, In : Heart. 99, 14, p. 1041-1047 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Cell penetrating peptide conjugated polymeric micelles as a high performance versatile nonviral gene carrier

Layek, B. & Singh, J., Nov 11 2013, In : Biomacromolecules. 14, 11, p. 4071-4081 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cell penetrating peptide tethered bi-ligand liposomes for delivery to brain in vivo: Biodistribution and transfection

Sharma, G., Modgil, A., Layek, B., Arora, K., Sun, C., Law, B. & Singh, J., Apr 10 2013, In : Journal of Controlled Release. 167, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Circulating microRNAs as biomarkers for inflammatory diseases

Mi, S., Zhang, J., Zhang, W. & Huang, R. S., Jan 1 2013, In : MicroRNA (Shāriqah, United Arab Emirates). 2, 1, p. 63-71 9 p.

Research output: Contribution to journalReview article

45 Scopus citations

Clinical applications of next-generation sequencing: The 2013 human genome variation society scientific meeting

Ellard, S., Patrinos, G. P. & Oetting, W. S., Nov 1 2013, In : Human mutation. 34, 11, p. 1583-1587 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Clinical Phenotypes of psychosis in the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP)

Tamminga, C. A., Ivleva, E. I., Keshavan, M. S., Pearlson, G. D., Clementz, B. A., Witte, B., Morris, D. W., Bishop, J., Thaker, G. K. & Sweeney, J. A., Nov 1 2013, In : American Journal of Psychiatry. 170, 11, p. 1263-1274 12 p.

Research output: Contribution to journalArticle

142 Scopus citations

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

Epstein, A. A., Narayanasamy, P., Dash, P. K., High, R., Bathena, S. P. R., Gorantla, S., Poluektova, L. Y., Alnouti, Y., Gendelman, H. E. & Boska, M. D., Dec 1 2013, In : Journal of Neuroimmune Pharmacology. 8, 5, p. 1224-1238 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Computerized analysis of a verbal fluency test

Ryan, J. O., Pakhomov, S. V., Marino, S. E., Bernick, C. & Banks, S., Jan 1 2013, Short Papers. Association for Computational Linguistics (ACL), p. 884-889 6 p. (ACL 2013 - 51st Annual Meeting of the Association for Computational Linguistics, Proceedings of the Conference; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Co-occurrence of autism, childhood psychosis, and intellectual disability associated with a de novo 3q29 microdeletion

Sagar, A., Bishop, J. R., Tessman, D. C., Guter, S., Martin, C. L. & Cook, E. H., Apr 1 2013, In : American Journal of Medical Genetics, Part A. 161, 4, p. 845-849 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Correlation of specific amyloid-β oligomers with tau in cerebrospinal fluid from cognitively normal older adults

Handoko, M., Grant, M., Kuskowski, M., Zahs, K. R., Wallin, A., Blennow, K. & Ashe, K. H., May 2013, In : JAMA Neurology. 70, 5, p. 594-599 6 p.

Research output: Contribution to journalArticle

52 Scopus citations

Determination of the dominant arachidonic acid cytochrome P450 monooxygenases in rat heart, lung, kidney, and liver: Protein expression and metabolite kinetics

El-Sherbeni, A. A., Aboutabl, M. E., Zordoky, B. N. M., Anwar-Mohamed, A. & El-Kadi, A. O. S., Jan 1 2013, In : AAPS Journal. 15, 1, p. 112-122 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Differential effects of soluble epoxide hydrolase inhibition and CYP2J2 overexpression on postischemic cardiac function in aged mice

Chaudhary, K. R., Zordoky, B. N. M., Edin, M. L., Alsaleh, N., El-Kadi, A. O. S., Zeldin, D. C. & Seubert, J. M., Jul 1 2013, In : Prostaglandins and Other Lipid Mediators. 104-105, p. 8-17 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Effect of paroxetine on physiological response to stress and smoking

Kotlyar, M., Al'Absi, M., Thuras, P., Vuchetich, J. P., Adson, D. E., Nowack, A. L. & Hatsukami, D. K., Apr 2013, In : Psychosomatic medicine. 75, 3, p. 236-243 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
116 Scopus citations

Epilepsy, behavior, and art (Epilepsy, Brain, and Mind, part 1)

Rektor, I., Schachter, S. C., Arzy, S., Baloyannis, S. J., Bazil, C., Brázdil, M., Engel, J., Helmstaedter, G., Hesdorffer, D. C., Jones-Gotman, M., Kesner, L., Komárek, V., Krämer, G., Leppik, I. E., Mann, M. W., Mula, M., Risse, G. L., Stoker, G. W., Kasteleijn- Nolst Trenité, D. G. A., Trimble, M. & 2 others, Tyrliková, I. & Korczyn, A. D., Aug 1 2013, In : Epilepsy and Behavior. 28, 2, p. 261-282 22 p.

Research output: Contribution to journalReview article

13 Scopus citations

Extended-release antiepileptic drugs: A comparison of pharmacokinetic parameters relative to original immediate-release formulations

Leppik, I. E. & Hovinga, C. A., Jan 1 2013, In : Epilepsia. 54, 1, p. 28-35 8 p.

Research output: Contribution to journalReview article

34 Scopus citations

Ex vivo porcine vaginal mucosal model of infection for determining effectiveness and toxicity of antiseptics

Anderson, M. J., Scholz, M. T., Parks, P. J. & Peterson, M. L., Sep 1 2013, In : Journal of Applied Microbiology. 115, 3, p. 679-688 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease

Cheng, S., Cao, D., Hottman, D. A., Yuan, L., Bergo, M. O. & Li, L., Dec 13 2013, In : Journal of Biological Chemistry. 288, 50, p. 35952-35960 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Feasibility study of a caregiver seizure alert system in canine epilepsy

Coles, L. D., Patterson, E. E., Sheffield, W. D., Mavoori, J., Higgins, J., Michael, B., Leyde, K., Cloyd, J. C., Litt, B., Vite, C. & Worrell, G. A., Oct 1 2013, In : Epilepsy Research. 106, 3, p. 456-460 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

French, J. D., Ghoussaini, M., Edwards, S. L., Meyer, K. B., Michailidou, K., Ahmed, S., Khan, S., Maranian, M. J., O'Reilly, M., Hillman, K. M., Betts, J. A., Carroll, T., Bailey, P. J., Dicks, E., Beesley, J., Tyrer, J., Maia, A. T., Beck, A., Knoblauch, N. W., Chen, C. & 191 others, Kraft, P., Barnes, D., González-Neira, A., Alonso, M. R., Herrero, D., Tessier, D. C., Vincent, D., Bacot, F., Luccarini, C., Baynes, C., Conroy, D., Dennis, J., Bolla, M. K., Wang, Q., Hopper, J. L., Southey, M. C., Schmidt, M. K., Broeks, A., Verhoef, S., Cornelissen, S., Muir, K., Lophatananon, A., Stewart-Brown, S., Siriwanarangsan, P., Fasching, P. A., Loehberg, C. R., Ekici, A. B., Beckmann, M. W., Peto, J., Dos Santos Silva, I., Johnson, N., Aitken, Z., Sawyer, E. J., Tomlinson, I., Kerin, M. J., Miller, N., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guénel, P., Truong, T., Laurent-Puig, P., Menegaux, F., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Milne, R. L., Zamora, M. P., Arias Perez, J. I., Benitez, J., Anton-Culver, H., Brenner, H., Müller, H., Arndt, V., Stegmaier, C., Meindl, A., Lichtner, P., Schmutzler, R. K., Engel, C., Brauch, H., Hamann, U., Justenhoven, C., Aaltonen, K., Heikkilä, P., Aittomäki, K., Blomqvist, C., Matsuo, K., Ito, H., Iwata, H., Sueta, A., Bogdanova, N. V., Antonenkova, N. N., Dörk, T., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Wu, A. H., Tseng, C. C., Van Den Berg, D., Stram, D. O., Lambrechts, D., Peeters, S., Smeets, A., Floris, G., Chang-Claude, J., Rudolph, A., Nickels, S., Flesch-Janys, D., Radice, P., Peterlongo, P., Bonanni, B., Sardella, D., Couch, F. J., Wang, X., Pankratz, V. S., Lee, A., Giles, G. G., Severi, G., Baglietto, L., Haiman, C. A., Henderson, B. E., Schumacher, F., Le Marchand, L., Simard, J., Goldberg, M. S., Labrèche, F., Dumont, M., Teo, S. H., Yip, C. H., Ng, C. H., Vithana, E. N., Kristensen, V., Zheng, W., Deming-Halverson, S., Shrubsole, M., Long, J., Winqvist, R., Pylkäs, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Devilee, P., Seynaeve, C., García-Closas, M., Figueroa, J., Chanock, S. J., Lissowska, J., Czene, K., Klevebring, D., Schoof, N., Hooning, M. J., Martens, J. W. M., Collée, J. M., Tilanus-Linthorst, M., Hall, P., Li, J., Liu, J., Humphreys, K., Shu, X. O., Lu, W., Gao, Y. T., Cai, H., Cox, A., Balasubramanian, S. P., Blot, W., Signorello, L. B., Cai, Q., Pharoah, P. D. P., Healey, C. S., Shah, M., Pooley, K. A., Kang, D., Yoo, K. Y., Noh, D. Y., Hartman, M., Miao, H., Sng, J. H., Sim, X., Jakubowska, A., Lubinski, J., Jaworska-Bieniek, K., Durda, K., Sangrajrang, S., Gaborieau, V., McKay, J., Toland, A. E., Ambrosone, C. B., Yannoukakos, D., Godwin, A. K., Shen, C. Y., Hsiung, C. N., Wu, P. E., Chen, S. T., Swerdlow, A., Ashworth, A., Orr, N., Schoemaker, M. J., Ponder, B. A. J., Nevanlinna, H., Brown, M. A., Chenevix-Trench, G., Easton, D. F. & Dunning, A. M., Apr 4 2013, In : American Journal of Human Genetics. 92, 4, p. 489-503 15 p.

Research output: Contribution to journalArticle

137 Scopus citations

Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study

Kraja, A. T., Borecki, I. B., Tsai, M. Y., Ordovas, J. M., Hopkins, P. N., Lai, C. Q., Frazier-Wood, A. C., Straka, R. J., Hixson, J. E., Province, M. A. & Arnett, D. K., Feb 1 2013, In : Lipids. 48, 2, p. 155-165 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity

Frazier-Wood, A. C., Manichaikul, A., Aslibekyan, S., Borecki, I. B., Goff, D. C., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Post, W. S., Rich, S. S., Sale, M. M., Siscovick, D., Straka, R. J., Tiwari, H. K., Tsai, M. Y., Rotter, J. I. & Arnett, D. K., Apr 1 2013, In : Human Genetics. 132, 4, p. 405-413 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

Couch, F. J., Wang, X., McGuffog, L., Lee, A., Olswold, C., Kuchenbaecker, K. B., Soucy, P., Fredericksen, Z., Barrowdale, D., Dennis, J., Gaudet, M. M., Dicks, E., Kosel, M., Healey, S., Sinilnikova, O. M., Lee, A., Bacot, F., Vincent, D., Hogervorst, F. B. L., Peock, S. & 472 others, Stoppa-Lyonnet, D., Jakubowska, A., Radice, P., Schmutzler, R. K., Domchek, S. M., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Greene, M. H., Karlan, B. Y., Garber, J., Phelan, C. M., Weitzel, J. N., Montagna, M., Olah, E., Andrulis, I. L., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Nevanlinna, H., Osorio, A., Terry, M. B., Daly, M. B., van Rensburg, E. J., Hamann, U., Ramus, S. J., Ewart Toland, A., Caligo, M. A., Olopade, O. I., Tung, N., Claes, K., Beattie, M. S., Southey, M. C., Imyanitov, E. N., Tischkowitz, M., Janavicius, R., John, E. M., Kwong, A., Diez, O., Balmaña, J., Barkardottir, R. B., Arun, B. K., Rennert, G., Teo, S. H., Ganz, P. A., Campbell, I., van der Hout, A. H., van Deurzen, C. H. M., Seynaeve, C., Gómez Garcia, E. B., van Leeuwen, F. E., Meijers-Heijboer, H. E. J., Gille, J. J. P., Ausems, M. G. E. M., Blok, M. J., Ligtenberg, M. J. L., Rookus, M. A., Devilee, P., Verhoef, S., van Os, T. A. M., Wijnen, J. T., Frost, D., Ellis, S., Fineberg, E., Platte, R., Evans, D. G., Izatt, L., Eeles, R. A., Adlard, J., Eccles, D. M., Cook, J., Brewer, C., Douglas, F., Hodgson, S., Morrison, P. J., Side, L. E., Donaldson, A., Houghton, C., Rogers, M. T., Dorkins, H., Eason, J., Gregory, H., McCann, E., Murray, A., Calender, A., Hardouin, A., Berthet, P., Delnatte, C., Nogues, C., Lasset, C., Houdayer, C., Leroux, D., Rouleau, E., Prieur, F., Damiola, F., Sobol, H., Coupier, I., Venat-Bouvet, L., Castera, L., Gauthier-Villars, M., Léoné, M., Pujol, P., Mazoyer, S., Bignon, Y. J., Złowocka-Perłowska, E., Gronwald, J., Lubinski, J., Durda, K., Jaworska, K., Huzarski, T., Spurdle, A. B., Viel, A., Peissel, B., Bonanni, B., Melloni, G., Ottini, L., Papi, L., Varesco, L., Tibiletti, M. G., Peterlongo, P., Volorio, S., Manoukian, S., Pensotti, V., Arnold, N., Engel, C., Deissler, H., Gadzicki, D., Gehrig, A., Kast, K., Rhiem, K., Meindl, A., Niederacher, D., Ditsch, N., Plendl, H., Preisler-Adams, S., Engert, S., Sutter, C., Varon-Mateeva, R., Wappenschmidt, B., Weber, B. H. F., Arver, B., Stenmark-Askmalm, M., Loman, N., Rosenquist, R., Einbeigi, Z., Nathanson, K. L., Rebbeck, T. R., Blank, S. V., Cohn, D. E., Rodriguez, G. C., Small, L., Friedlander, M., Bae-Jump, V. L., Fink-Retter, A., Rappaport, C., Gschwantler-Kaulich, D., Pfeiler, G., Tea, M. K., Lindor, N. M., Kaufman, B., Shimon Paluch, S., Laitman, Y., Skytte, A. B., Gerdes, A. M., Pedersen, I. S., Moeller, S. T., Kruse, T. A., Jensen, U. B., Vijai, J., Sarrel, K., Robson, M., Kauff, N., Mulligan, A. M., Glendon, G., Ozcelik, H., Ejlertsen, B., Nielsen, F. C., Jønson, L., Andersen, M. K., Ding, Y. C., Steele, L., Foretova, L., Teulé, A., Lazaro, C., Brunet, J., Pujana, M. A., Mai, P. L., Loud, J. T., Walsh, C., Lester, J., Orsulic, S., Narod, S. A., Herzog, J., Sand, S. R., Tognazzo, S., Agata, S., Vaszko, T., Weaver, J., Stavropoulou, A. V., Buys, S. S., Romero, A., de la Hoya, M., Aittomäki, K., Muranen, T. A., Duran, M., Chung, W. K., Lasa, A., Dorfling, C. M., Miron, A., Benitez, J., Senter, L., Huo, D., Chan, S. B., Sokolenko, A. P., Chiquette, J., Tihomirova, L., Friebel, T. M., Agnarsson, B. A., Lu, K. H., Lejbkowicz, F., James, P. A., Hall, P., Dunning, A. M., Tessier, D., Cunningham, J., Slager, S. L., Wang, C., Hart, S., Stevens, K., Simard, J., Pastinen, T., Pankratz, V. S., Offit, K., Easton, D. F., Chenevix-Trench, G., Antoniou, A. C., Thorne, H., Niedermayr, E., Borg, Å., Olsson, H., Jernström, H., Henriksson, K., Harbst, K., Soller, M., Loman, N., Kristoffersson, U., Öfverholm, A., Nordling, M., Karlsson, P., Einbeigi, Z., von Wachenfeldt, A., Liljegren, A., Lindblom, A., Arver, B., Bustinza, G. B., Rantala, J., Melin, B., Ardnor, C. E., Emanuelsson, M., Ehrencrona, H., Pigg, M. H., Rosenquist, R., Stenmark-Askmalm, M., Liedgren, S., Rookus, M. A., Hogervorst, F. B. L., Verhoef, S., van Leeuwen, F. E., Schmidt, M. K., de Lange, J., Collée, J. M., van den Ouweland, A. M. W., Hooning, M. J., Seynaeve, C., van Asperen, C. J., Wijnen, J. T., Tollenaar, R. A., Devilee, P., van Cronenburg, T. C. T. E. F., Kets, C. M., Mensenkamp, A. R., Ausems, M. G. E. M., van der Luijt, R. B., Aalfs, C. M., van Os, T. A. M., Gille, J. J. P., Waisfisz, Q., Meijers-Heijboer, H. E. J., Gómez-Garcia, E. B., Blok, M. J., Oosterwijk, J. C., van der Hout, H., Mourits, M. J., de Bock, G. H., Peock, S., Frost, D., Ellis, S., Fineberg, E., Platte, R., Miedzybrodzka, Z., Gregory, H., Morrison, P., Jeffers, L., Cole, T., Ong, K. R., Hoffman, J., Donaldson, A., James, M., Tischkowitz, M., Paterson, J., Taylor, A., Murray, A., Rogers, M. T., McCann, E., Kennedy, M. J., Barton, D., Porteous, M., Drummond, S., Brewer, C., Kivuva, E., Searle, A., Goodman, S., Hill, K., Davidson, R., Murday, V., Bradshaw, N., Snadden, L., Longmuir, M., Watt, C., Gibson, S., Haque, E., Tobias, E., Duncan, A., Izatt, L., Jacobs, C., Langman, C., Dorkins, H., Brady, A., Melville, A., Randhawa, K., Barwell, J., Adlard, J., Serra-Feliu, G., Ellis, I., Houghton, C., Lalloo, F., Taylor, J., Side, L., Male, A., Berlin, C., Eason, J., Collier, R., Douglas, F., Claber, O., Jobson, I., Walker, L., McLeod, D., Halliday, D., Durell, S., Stayner, B., Eeles, R. A., Shanley, S., Rahman, N., Houlston, R., Stormorken, A., Bancroft, E., Page, E., Ardern-Jones, A., Kohut, K., Wiggins, J., Castro, E., Killick, E., Martin, S., Rea, G., Kulkarni, A., Cook, J., Quarrell, O., Bardsley, C., Hodgson, S., Goff, S., Brice, G., Winchester, L., Eddy, C., Tripathi, V., Attard, V., Lehmann, A., Eccles, D., Lucassen, A., Crawford, G., McBride, D., Smalley, S., Sinilnikova, O., Mazoyer, S., Damiola, F., Barjhoux, L., Verny-Pierre, C., Giraud, S., Léone, M., Stoppa-Lyonnet, D., Gauthier-Villars, M., Buecher, B., Houdayer, C., Moncoutier, V., Belotti, M., Tirapo, C., de Pauw, A., Bressac-de-Paillerets, B., Caron, O., Bignon, Y. J., Uhrhammer, N., Lasset, C., Bonadona, V., Handallou, S., Hardouin, A., Berthet, P., Sobol, H., Bourdon, V., Noguchi, T., Remenieras, A., Eisinger, F., Coupier, I., Pujol, P., Peyrat, J. P., Fournier, J., Révillion, F., Vennin, P., Adenis, C., Rouleau, E., Lidereau, R., Demange, L., Nogues, C., Muller, D., Fricker, J. P., Barouk-Simonet, E., Bonnet, F., Bubien, V., Sevenet, N., Longy, M., Toulas, C., Guimbaud, R., Gladieff, L., Feillel, V., Leroux, D., Dreyfus, H., Rebischung, C., Peysselon, M., Coron, F., Faivre, L., Prieur, F., Lebrun, M., Kientz, C., Ferrer, S. F., Frénay, M., Vénat-Bouvet, L., Delnatte, C., Mortemousque, I., Coulet, F., Colas, C., Soubrier, F., Sokolowska, J., Bronner, M., Lynch, H. T., Snyder, C. L., Angelakos, M., Maskiell, J. & Dite, G., Jan 1 2013, In : PLoS genetics. 9, 3, e1003212.

Research output: Contribution to journalArticle

173 Scopus citations

Genome-wide discovery of genetic variants affecting tamoxifen sensitivity and their clinical and functional validation

Weng, L., Ziliak, D., Im, H. K., Gamazon, E. R., Philips, S., Nguyen, A. T., Desta, Z., Skaar, T. C., Flockhart, D. A. & Huang, R. S., Jul 1 2013, In : Annals of Oncology. 24, 7, p. 1867-1873 7 p., mdt125.

Research output: Contribution to journalArticle

6 Scopus citations

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations

Wheeler, H. E., Gamazon, E. R., Stark, A. L., O'Donnell, P. H., Gorsic, L. K., Huang, R. S., Cox, N. J. & Dolan, M. E., Feb 1 2013, In : Pharmacogenomics Journal. 13, 1, p. 35-43 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Getting Ready for the Human Phenome Project: The 2012 Forum of the Human Variome Project

Oetting, W. S., Robinson, P. N., Greenblatt, M. S., Cotton, R. G., Beck, T., Carey, J. C., Doelken, S. C., Girdea, M., Groza, T., Hamilton, C. M., Hamosh, A., Kerner, B., Macarthur, J. A. L., Maglott, D. R., Mons, B., Rehm, H. L., Schofield, P. N., Searle, B. A., Smedley, D., Smith, C. L. & 3 others, Bernstein, I. T., Zankl, A. & Zhao, E. Y., Apr 1 2013, In : Human mutation. 34, 4, p. 661-666 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Health-related quality of life in kidney donors from the last five decades: Results from the RELIVE study

Gross, C. R., Messersmith, E. E., Hong, B. A., Jowsey, S. G., Jacobs, C., Gillespie, B. W., Taler, S. J., Matas, A. J., Leichtman, A., Merion, R. M. & Ibrahim, H. N., Nov 1 2013, In : American Journal of Transplantation. 13, 11, p. 2924-2934 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

HIV pre-exposure prophylaxis trials: the road to success

Nicol, M. R., Adams, J. L. & Kashuba, A. DM., Mar 2013, In : Clinical Investigation. 3, p. 295-308

Research output: Contribution to journalArticle

HIV serostatus differs by catechol-O-methyltransferase Val158Met genotype

Sundermann, E. E., Bishop, J. R., Rubin, L. H., Aouizerat, B., Wilson, T. E., Weber, K. M., Cohen, M., Golub, E., Anastos, K., Liu, C., Crystal, H., Pearce, C. L. & Maki, P. M., Jul 17 2013, In : AIDS. 27, 11, p. 1779-1782 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Inflammation in the setting of chronic allograft dysfunction post-kidney transplant: Phenotype and genotype

Israni, A. K., Leduc, R. E., Jacobson, P. A., Wildebush, W., Guan, W., Schladt, D., Matas, A. J. & Oetting, W. S., May 1 2013, In : Clinical Transplantation. 27, 3, p. 348-358 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Integrative genomics: Quantifying significance of phenotype-genotype relationships from multiple sources of high-throughput data

Gamazon, E. R., Stephanie Huang, R., Eileen Dolan, M., Cox, N. J. & Im, H. K., Sep 11 2013, In : Frontiers in Genetics. 4, MAY, Article 202.

Research output: Contribution to journalArticle

5 Scopus citations