Experimental and Clinical Pharmacology

Research Output

2014

Functional Fcgamma Receptor Polymorphisms Are Associated with Human Allergy

Wu, J., Lin, R., Huang, J., Guan, W., Oetting, W. S., Sriramarao, P. & Blumenthal, M. N., Feb 21 2014, In : PloS one. 9, 2, e89196.

Research output: Contribution to journalArticle

13 Scopus citations

Gamma-Aminobutyric Acid System Genes-No Evidence for a Role in Alcohol Use and Abuse in a Community-Based Sample

Irons, D. E., Iacono, W. G., Oetting, W. S., Kirkpatrick, R. M., Vrieze, S. I., Miller, M. B. & Mcgue, M., Apr 2014, In : Alcoholism: Clinical and Experimental Research. 38, 4, p. 938-947 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol

Feitosa, M. F., Wojczynski, M. K., Straka, R., Kammerer, C. M., Lee, J. H., Kraja, A. T., Christensen, K., Newman, A. B., Province, M. A. & Borecki, I. B., Jan 1 2014, In : Frontiers in Genetics. 5, JUN, Article 159.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic biomarkers for fluorouracil toxicity prediction: The long road to clinical utility

Lee, A. M. & Diasio, R. B., Apr 1 2014, In : Journal of Clinical Oncology. 32, 10, p. 989-990 2 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Genetic determinants of selective serotonin reuptake inhibitor related sexual dysfunction

Stevenson, J. M. & Bishop, J. R., Nov 1 2014, In : Pharmacogenomics. 15, 14, p. 1791-1806 16 p.

Research output: Contribution to journalReview article

4 Scopus citations

Genetic predictor of working memory and prefrontal function in women with HIV

Sundermann, E. E., Bishop, J. R., Rubin, L. H., Little, D. M., Meyer, V. J., Martin, E., Weber, K., Cohen, M. & Maki, P. M., Jan 1 2014, In : Journal of neurovirology. 21, 1, p. 81-91 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrate

Frazier-Wood, A. C., Wojczynski, M. K., Borecki, I. B., Hopkins, P. N., Lai, C. Q., Ordovas, J. M., Straka, R. J., Tsai, M. Y., Tiwari, H. K. & Arnett, D. K., Aug 25 2014, In : Biology. 3, 3, p. 536-550 15 p.

Research output: Contribution to journalArticle

1 Scopus citations

Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response

An, P., Straka, R. J., Pollin, T. I., Feitosa, M. F., Wojczynski, M. K., Daw, E. W., O'Connell, J. R., Gibson, Q., Ryan, K. A., Hopkins, P. N., Tsai, M. Y., Lai, C. Q., Province, M. A., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Jul 2014, In : Human Genetics. 133, 7, p. 919-930 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genome-wide interrogation of longitudinal FEV1in children with asthma

Wu, K., Gamazon, E. R., Im, H. K., Geeleher, P., White, S. R., Solway, J., Clemmer, G. L., Weiss, S. T., Tantisira, K. G., Cox, N. J., Ratain, M. J. & Huang, R. S., Sep 15 2014, In : American journal of respiratory and critical care medicine. 190, 6, p. 619-627 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

HDL and cognition in neurodegenerative disorders

Hottman, D. A., Chernick, D., Cheng, S., Wang, Z. & Li, L., Dec 1 2014, In : Neurobiology of Disease. 72, Part A, p. 22-36 15 p.

Research output: Contribution to journalReview article

56 Scopus citations

Healthcare utilization and costs in persons with insomnia in a managed care population

Anderson, L. H., Whitebird, R. R., Schultz, J., McEvoy, C. E., Kreitzer, M. J. & Gross, C. R., May 2014, In : American Journal of Managed Care. 20, 5, p. e157-e165

Research output: Contribution to journalArticle

8 Scopus citations

Heart Failure

Hamza, S. M., Sharma, N., Sung, M. M., Zordoky, B. N., Kantor, P. F. & Dyck, J. R. B., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 971-994 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hexanoic acid and polyethylene glycol double grafted amphiphilic chitosan for enhanced gene delivery: Influence of hydrophobic and hydrophilic substitution degree

Layek, B., Haldar, M. K., Sharma, G., Lipp, L., Mallik, S. & Singh, J., Mar 3 2014, In : Molecular Pharmaceutics. 11, 3, p. 982-994 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

How mindfulness changed my sleep: Focus groups with chronic insomnia patients

Hubbling, A., Reilly-Spong, M., Kreitzer, M. J. & Gross, C. R., Feb 10 2014, In : BMC Complementary and Alternative Medicine. 14, 50.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Identifying and validating a combined mRNA and MicroRNA signature in response to imatinib treatment in a chronic myeloid leukemia cell line

Bhutra, S., Lenkala, D., LaCroix, B., Ye, M. & Huang, R. S., Dec 15 2014, In : PloS one. 9, 12, e115003.

Research output: Contribution to journalArticle

8 Scopus citations

Increased expression of GCNT1 is associated with altered O-glycosylation of PSA, PAP, and MUC1 in human prostate cancers

Chen, Z., Gulzar, Z. G., St. Hill, C. A., Walcheck, B. & Brooks, J. D., Jul 2014, In : Prostate. 74, 10, p. 1059-1067 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

In search of rare variants: Preliminary results from whole genome sequencing of 1,325 individuals with psychophysiological endophenotypes

Vrieze, S. I., Malone, S. M., Vaidyanathan, U., Kwong, A., Kang, H. M., Zhan, X., Flickinger, M., Irons, D., Jun, G., Locke, A. E., Pistis, G., Porcu, E., Levy, S., Myers, R. M., Oetting, W., Mcgue, M., Abecasis, G. & Iacono, W. G., Dec 1 2014, In : Psychophysiology. 51, 12, p. 1309-1320 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity

LaCroix, B., Gamazon, E. R., Lenkala, D., Im, H. K., Geeleher, P., Ziliak, D., Cox, N. J. & Huang, R. S., Apr 16 2014, In : BMC Genomics. 15, 1, 292.

Research output: Contribution to journalArticle

19 Scopus citations

In vitro and in vivo evaluation of water-soluble iminophosphorane ruthenium(II) compounds. A potential chemotherapeutic agent for triple negative breast cancer

Frik, M., Martínez, A., Elie, B. T., Gonzalo, O., Ramírez De Mingo, D., Sanaú, M., Sánchez-Delgado, R., Sadhukha, T., Prabha, S., Ramos, J. W., Marzo, I. & Contel, M., Dec 11 2014, In : Journal of medicinal chemistry. 57, 23, p. 9995-10012 18 p.

Research output: Contribution to journalArticle

49 Scopus citations

Lymphatic dysregulation in intestinal inflammation: New insights into inflammatory bowel disease pathomechanisms

Becker, F., Yi, P., Al-Kofahi, M., Ganta, V. C., Morris, J. & Alexander, J. S., Mar 2014, In : Lymphology. 47, 1, p. 3-27 25 p.

Research output: Contribution to journalReview article

22 Scopus citations

Mindfulness: A Nonpharmacological Approach to Diabetes Management

Gross, C. R. & Reibel, D. K., Mar 21 2014, The Wiley Blackwell Handbook of Mindfulness. Wiley Blackwell, Vol. 1-2. p. 898-912 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Mindfulness: A Non-pharmacological Approach to Diabetes Management

Gross, C. R. & Reibel, D. K., Feb 28 2014, The Wiley Blackwell Handbook of Mindfulness Volume II. Ie, A., Ngnoumen, C. T. & Langer, E. J. (eds.). Chichester, UK: John Wiley & Sons, Ltd

Research output: Chapter in Book/Report/Conference proceedingChapter

Model-based lamotrigine clearance changes during pregnancy: Clinical implication

Polepally, A. R., Pennell, P. B., Brundage, R. C., Stowe, Z. N., Newport, D. J., Viguera, A. C., Ritchie, J. C. & Birnbaum, A. K., Jan 1 2014, In : Annals of Clinical and Translational Neurology. 1, 2, p. 99-106 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Multifunctional polymersomes for cytosolic delivery of gemcitabine and doxorubicin to cancer cells

Nahire, R., Haldar, M. K., Paul, S., Ambre, A. H., Meghnani, V., Layek, B., Katti, K. S., Gange, K. N., Singh, J., Sarkar, K. & Mallik, S., Aug 2014, In : Biomaterials. 35, 24, p. 6482-6497 16 p.

Research output: Contribution to journalArticle

60 Scopus citations

Next-generation sequencing for lung cancer

Wu, K., Huang, R. S., House, L. & Cho, W. C., 2014, In : Chinese Journal of Lung Cancer. 17, 1, p. C1-C12

Research output: Contribution to journalArticle

Nod2 deficiency protects mice from cholestatic liver disease by increasing renal excretion of bile acids

Wang, L., Hartmann, P., Haimerl, M., Bathena, S. P., Sjöwall, C., Almer, S., Alnouti, Y., Hofmann, A. F. & Schnabl, B., Jun 2014, In : Journal of Hepatology. 60, 6, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
41 Scopus citations

Outcome measures of behavioral weight loss programs in perimenopause

Zargarian, N., Lindquist, R., Gross, C. R. & Treat-Jacobson, D., Jan 1 2014, In : Southern Medical Journal. 107, 8, p. 486-496 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Pharmacokinetics and pharmacodynamics of intravenous baclofen in dogs: A preliminary study

Scherkenbach, L. A., Coles, L. D., Patterson, E. E., Cloyd, J. C., Krach, L. E. & Kriel, R. L., Jul 2014, In : Journal of Pharmacy and Pharmacology. 66, 7, p. 935-942 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pharmacometric characterization of efavirenz developmental pharmacokinetics and pharmacogenetics in HIV-Infected children

Salem, A. H., Fletcher, C. V. & Brundage, R. C., Jan 1 2014, In : Antimicrobial agents and chemotherapy. 58, 1, p. 136-143 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Poly-omic prediction of complex traits: OmicKriging

Wheeler, H. E., Aquino-Michaels, K., Gamazon, E. R., Trubetskoy, V. V., Dolan, M. E., Huang, R. S., Cox, N. J. & Im, H. K., Jul 2014, In : Genetic epidemiology. 38, 5, p. 402-415 14 p.

Research output: Contribution to journalArticle

22 Scopus citations
10 Scopus citations

Protein Prenylation and Synaptic Plasticity: Implications for Alzheimer’s Disease

Hottman, D. A. & Li, L., Oct 2 2014, In : Molecular neurobiology. 50, 1, p. 177-185 9 p.

Research output: Contribution to journalReview article

27 Scopus citations

Quality of life in elderly kidney transplant recipients

Weber, M., Faravardeh, A., Jackson, S., Berglund, D., Spong, R., Matas, A. J., Gross, C. R. & Ibrahim, H. N., Oct 1 2014, In : Journal of the American Geriatrics Society. 62, 10, p. 1877-1882 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Reduced levels of vasopressin and reduced behavioral modulation of oxytocin in psychotic disorders

Rubin, L. H., Sue Carter, C., Bishop, J. R., Pournajafi-Nazarloo, H., Drogos, L. L., Kristian Hill, S., Ruocco, A. C., Keedy, S. K., Reilly, J. L., Keshavan, M. S., Pearlson, G. D., Tamminga, C. A., Gershon, E. S. & Sweeney, J. A., Nov 1 2014, In : Schizophrenia bulletin. 40, 6, p. 1374-1384 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Report of the 2013-2014 Academic Affairs Committee

Cain, J., Conway, J. M., DiVall, M. V., Erstad, B. L., Lockman, P. R., Ressler, J. C., Schwartz, A. H., Stolte, S. & Nemire, R. E., Dec 15 2014, In : American Journal of Pharmaceutical Education. 78, 10, p. 1-8 8 p., S23.

Research output: Contribution to journalArticle

16 Scopus citations

Safety of an intravenous formulation of lamotrigine

Conway, J. M., Birnbaum, A. K., Leppik, I. E., Pennell, P. B., White, J. R., Rarick, J. O. & Remmel, R. P., May 2014, In : Seizure. 23, 5, p. 390-392 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Satisfaction with life among living kidney donors: A relive study of long-term donor outcomes

Messersmith, E. E., Gross, C. R., Beil, C. A., Gillespie, B. W., Jacobs, C., Taler, S. J., Merion, R. M., Jowsey, S. G., Leichtman, A. B. & Hong, B. A., Jan 1 2014, In : Transplantation. 98, 12, p. 1294-1300 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Short communication: Cheminformatics analysis to identify predictors of antiviral drug penetration into the female genital tract

Thompson, C. G., Sedykh, A., Nicol, M. R., Muratov, E., Fourches, D., Tropsha, A. & Kashuba, A. D. M., Jan 1 2014, In : AIDS Research and Human Retroviruses. 30, 11, p. 1058-1064 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Simvastatin treatment enhances NMDAR-mediated synaptic transmission by upregulating the surface distribution of the GluN2B subunit

Parent, M. A. L. T., Hottman, D. A., Cheng, S., Zhang, W., McMahon, L. L., Yuan, L. L. & Li, L., Jul 2014, In : Cellular and Molecular Neurobiology. 34, 5, p. 693-705 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours

Khatri, A., Williams, B. W., Fisher, J., Brundage, R. C., Gurvich, V. J., Lis, L. G., Skubitz, K. M., Dudek, A. Z., Greeno, E. W., Kratzke, R. A., Lamba, J. K. & Kirstein, M. N., Jan 21 2014, In : British Journal of Cancer. 110, 2, p. 304-312 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Student-generated, faculty-vetted multiple-choice questions: Value, participant satisfaction, and workload

Schullo-Feulner, A., Janke, K. K., Chapman, S. A., Stanke, L., Undeberg, M. R., Taylor, C., Brown, R. W. & Straka, R. J., Jan 1 2014, In : Currents in Pharmacy Teaching and Learning. 6, 1, p. 15-21 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Surface microbiology of the iPad tablet computer and the potential to serve as a fomite in both inpatient practice settings as well as outside of the hospital environment

Hirsch, E. B., Raux, B. R., Lancaster, J. W., Mann, R. L. & Leonard, S. N., Oct 31 2014, In : PloS one. 9, 10, e111250.

Research output: Contribution to journalArticle

15 Scopus citations

Telomere length of recipients and living kidney donors and chronic graft dysfunction in kidney transplants

Oetting, W. S., Guan, W., Schladt, D. P., Wildebush, W. A., Becker, J., Thyagarajan, B., Jacobson, P. A., Matas, A. J. & Israni, A. K., Feb 15 2014, In : Transplantation. 97, 3, p. 325-329 5 p.

Research output: Contribution to journalArticle

16 Scopus citations
55 Scopus citations

The impact of microRNA expression on cellular proliferation

Lenkala, D., LaCroix, B., Gamazon, E. R., Geeleher, P., Im, H. K. & Huang, R. S., Jul 2014, In : Human Genetics. 133, 7, p. 931-938 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Treating epilepsy in the elderly: More art than science

Leppik, I. E. & Birnbaum, A. K., 2014, In : Cleveland Clinic journal of medicine. 81, 8, p. 499-500 2 p.

Research output: Contribution to journalEditorial

Triptolide preserves cognitive function and reduces neuropathology in a mouse model of Alzheimer's disease

Cheng, S., LeBlanc, K. J. & Li, L., Oct 2 2014, In : PloS one. 9, 10, 108845.

Research output: Contribution to journalArticle

21 Scopus citations

Use of a simplified nomogram to individualize digoxin dosing versus standard dosing practices in patients with heart failure

DiDomenico, R. J., Bress, A. P., Na-Thalang, K., Tsao, Y. Y., Groo, V. L., Deyo, K. L., Patel, S. R., Bishop, J. R. & Bauman, J. L., Nov 1 2014, In : Pharmacotherapy. 34, 11, p. 1121-1131 11 p.

Research output: Contribution to journalArticle

6 Scopus citations